CN1300605A - Medicine for treating allergic rhinitis - Google Patents
Medicine for treating allergic rhinitis Download PDFInfo
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- CN1300605A CN1300605A CN 00129396 CN00129396A CN1300605A CN 1300605 A CN1300605 A CN 1300605A CN 00129396 CN00129396 CN 00129396 CN 00129396 A CN00129396 A CN 00129396A CN 1300605 A CN1300605 A CN 1300605A
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Abstract
A medicine in the form of powder, block, honeyed pill or particle for treating allergic rhiritis is prepared from 10 Chinese-medicinal materials including xanthium fruit, ephedra, magnolia flower, dahurian angelica root, etc through freeze drying or drying in air, crushing, solvent extracting, proportioning, heating and sterilizing.
Description
The present invention relates to a kind of medicine for the treatment of of allergic rhinitis, specifically the Chinese patent drug of preparation take Chinese herbal medicine as raw material.
Allergic Rhinitis quantity is along with living standard improves, the factors such as air pollution increases the weight of are increasing, modern medicine thinks that its pathogenesis is actually the type Ⅰ allergy that occurs in schneiderian membrane, allergen enters human body through respiratory tract, process through macrophage, stimulate bone-marrow-derived lymphocyte to become thick liquid cell, the latter produces specificity antibody IgE, the IgE menses flow to and reach schneiderian membrane, be attached to mast cell in the schneiderian membrane with its Fc section, on the basicyte film, make schneiderian membrane be in sensitization, when allergenic substances enters schneiderian membrane again, be combined with the Fab of IgE antibody section, and make adjacent IgE that bridging occur, the result morphs the membrane structure of mast cell and basophil, discharge the number of chemical medium, be mainly histamine, kassinin kinin, leukotrienes, the ECF, prostanoid, platelet activating factor, serotonin etc., these media are by their each comfortable nasal mucosa vessels walls, acceptor on body of gland and the nerve endings, make little blood vessel dilatation, vasopermeability increases, ooze out increase, inflammatory cell infiltration, tissue edema, the nerve endings excitability strengthens, cause corresponding clinical symptoms and sign, clinically nasal drop commonly used, aerosol, histamine H1Receptor antagonist, vasoconstrictor and antibiotic medicine often can only symptomatic treatments, take stopgap measures and do not effect a permanent cure, and the specific immunotherapy curative effect produces slower. Allergic rhinitis in motherland's medical science is allergic rhinitis, and it is because the deficiency syndrome of the lung is defended the gas mistake admittedly, resists outer evil ability and weakens, and due to chill was invaded in an opponent's defence, dialectical executing controlled, and should admittedly show expelling wind and clearing away cold by warm lung.
Solution of the present invention is based on motherland's medical science to allergic rhinitis and the pathogenetic understanding of complication and principle of reatment. With reference to the modern pharmacological research achievement, from motherland's medicine treasure-house, filter out warm lung and admittedly show, expelling wind and clearing away cold, nourishing yin to moisten dryness, the natural plant that moistens the lung and relieve the cough, invigorates the spleen and benefits qi by the theory of traditional Chinese medical science prescription, skim the cream off milk, make its performance anti-allergic effects, regulate the T lymphocyte function, raise the cell factor of Th passage, interleukin 2 and r interferon, thereby suppress the allergic inflammation reaction, suppress inflammatory cell the gathering of rhinitis mucous membrane, reduced mast cell degranulation, reduced tissue edema.
(consumption is weight portion) that medicine of the present invention is made by following component:
Achene of Siberian cocklebur 6-20 part flower bud of lily magnolia 6-20 part root of Dahurain angelica 6-20 part
Chinese ephedra 3-10 part coix seed 6-20 part lily 6-20 part
Radix polygonati officinalis 5-15 part caulis bambusae in taenian 5-15 part cicada slough 6-20 part
Radix Glycyrrhizae 3-10 part
The prescription preferred weight ratio range of preparation medicine of the present invention is:
Achene of Siberian cocklebur 6-15 part flower bud of lily magnolia 6-15 part root of Dahurain angelica 6-15 part
Chinese ephedra 3-9 part coix seed 6-15 part lily 6-15 part
Radix polygonati officinalis 5-10 part caulis bambusae in taenian 5-10 part cicada slough 6-15 part
Radix Glycyrrhizae 3-8 part
The optimum weight proportioning of medicine of the present invention is:
12 parts of 12 parts of roots of Dahurain angelica of 12 parts of flower buds of lily magnolia of the achene of Siberian cocklebur
12 parts of 12 portions of lilies of 6 parts of coix seeds of Chinese ephedra
12 parts of 10 portions of cicada sloughs of 10 parts of caulis bambusae in taenians of radix polygonati officinalis
6 parts in Radix Glycyrrhizae
The medicine of said ratio be can be made into powder, piece agent, honeyed bolus or granule by the processing method of Chinese medicine, directly orally need not special processing.
The present invention forms nature and flavor, character, function and the pharmacological action of flavour of a drug:
| The medicine name | Former plant | Meridian distribution of property and flavor | Chemical analysis | Function with cure mainly | Pharmacological action | Remarks |
| The achene of Siberian cocklebur | Feverfew Siberian cocklebur Xanthium sibiricum P atr fruit medicine | Hot, bitter, temperature, return lung channel | Xanthostrumarin Xanthostrumar i-n alkaloid, resin vitamin C and pigment, dry fruit is fatty oily 9. 2%, and wherein linoleic acid accounts for 64.2%, oleic acid 26.8% | Dispelling cold and removing dampness, clearing the nasal passage is used for anemofrigid headache, nasosinusitis runny nose, rubella itch, arthritis with fixed pain caused by dampness contraction | Antibacterial, staphylococcus aureus there is inhibitory action. | This medicine is at Pharmacopoeia of the People's Republic of China P1 front page 28 pages of in January, 2000, Chemical Industry Press, and Chinese Pharmacopoeia Commission compiles. |
| The root of Dahurain angelica | The plant root of Dahurain angelica Angelic a dahnrica Benth etHo ok of umbellate form section, the f root is used as medicine | Hot, temperature, return stomach, large intestine, lung channel | Byak-angelicin Byak angelicin, Byakangelicol, oxypeucedanin, ammidin and isomeric compound, phellopterin etc. | Loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis is used for cold headache, pain in the supra-orbital bone, nasal obstruction, nasosinusitis, toothache etc. | Antibacterial have inhibitory action to Escherichia coli, typhoid bacillus, paratyphosum Bacterium, shigella dysenteriae, Pseudomonas aeruginosa etc. | This medicine ((Pharmacopoeia of People's Republic of China " 9 pages of P7. In January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P129 page or leaf, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor. |
| Radix Glycyrrhizae | Pulse family Radix Glycyrrhizae Glycyrrhiza uralenms Fisch root is used as medicine | Sweet, the property of distinguishing the flavor of is put down into cardiopulmonary, taste warp | Glycyrrhizic acid Glycyr r-hizin liquiritin, glycyrrhizin, isoliquiritigenin etc. | Tonifying middle-Jiao and Qi, purging intense heat and detonicating, moistening lung is eliminated the phlegm, and relaxes the property of medicine, and the emergency analgesic therapy is used for deficiency of the spleen causing weakness of QI, coughing with a lot of sputum, sore furuncle poison, abscess of throat etc. | The effect of cortex hormone of aadrenaline sample, to the detoxication of digestion systemic effect, on the impact of lipid-metabolism, antitussive effect analgesia anticonvulsant action etc. | This medicine is 5 pages of Pharmacopoeia of the People's Republic of China P6. In January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P233 page or leaf, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor. |
| The flower bud of lily magnolia | Magnoliacea plant hopes spring flower Magnolia biohdiiPamp bud be used as medicine | Hot, temperature, attach to the lung and stomach meridians | Contain volatile oil 2.86 % Main Ingredients and Appearances and be-2-pinene, dipentene, chavicol, methyl ether and citral. | Dispersing wind and cold, clearing the nasal passage are used for anemofrigid headache, nasal obstruction, stagnant, the turbid nasal discharge of nose | This medicine is 43 pages of Pharmacopoeia of the People's Republic of China P1. In January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. | |
| Chinese ephedra | Ephedraceae plant plait Chinese ephedra Ephe dr-asinice S tapf stem is used as medicine | Hot, temperature, return lung, bladder aluminium | Ephedrine, Chinese ephedra wet goods. | Pulvis Diaphoreticus is cold, freeings lung and relieving asthma, and inducing diuresis for removing edema is used for anemofrigid cold, uncomfortable in chestly breathes with cough, the geomantic omen edema, asthma and cough. | Relieving cough and asthma, stimulate sympathetic nerve, alleviate bronchial spasm, infected by influenza has inhibitory action | This medicine is 62 pages of Pharmacopoeia of the People's Republic of China P2, in January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P126, in January, 1980 front page ,-People's Health Publisher Hebei Medical College chief editor |
| Coix seed | The dry mature kernal of Qiao Benke plant Job's tears Coix L ac-ryma_jodi l.Var.ma-yu em Stapf, benevolence is used as medicine | Spleen, stomach, lung channel are returned in the sweet heart of a lotus seed, light, cold | Heart of a lotus seed benevolence ester, carbohydrate 79.17 %, fat 4.65% above protein 16.2%, steroidal compounds, amino acid, suitable octadecylene. | The invigorating the spleen excreting dampness except numbness antidiarrheal, clearing away heat and eliminating pus, is used for oedema, beriberi, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea, lung carbuncle, acute appendicitis etc. | To skeletal muscle and kinesitherapy nerve not the tip low concentration excitation is arranged, high concentration has the paralysis effect, and cancer cell is had inhibitory action. | This medicine is 09 page of Pharmacopoeia of the People's Republic of China P3, in January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P146, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor. |
| Lily | Liliaceous plant tiger lily Lilium Lancifoliam Thund stem is used as medicine | Sweet, cold, the thoughts of returning home, lung channel | Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing is used for deficiency of Yin chronic cough, blood-stained sputum, dysphoria palpitation with fear, and insomnia and dreamful sleep is absent-minded | This medicine is 00 page of Pharmacopoeia of the People's Republic of China P1, in January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P237, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor. | ||
| Cicada slough | The black grasshopper Cryptotympa n-apusfulata Fabrioius shell of cicada is used as medicine | Sweetly tremble with fear, return lung, Liver Channel | Contain a large amount of chitin potassium acetates, potassium chloride. | Loose wind heat extraction, moves back screen, spasmolysis at relieve sore throat, promoting eruption, is used for anemopyretic cold, pharyngalgia, hoarsen, measles without adequate eruption, rubella itch, hot eyes ocular, convulsion, lockjaw. | Contain potassium acetate and potassium chloride, arresting convulsion and diuresis are arranged. | This medicine is 02 page of Pharmacopoeia of the People's Republic of China P3, in January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P133, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor |
| Radix polygonati officinalis | Liliaceous plant radix polygonati officinalis Polygonatum odoratum DruceCr dry rhizome | Sweet, be slightly cold, attach to the lung and stomach meridians | D-Fructose D-MANNOSE D-Glucose galacturonic acid, radix polygonati officinalis levulan, OYJ pyridine--carboxylic acid | Nourishing yin to moisten dryness promotes the production of body fluid to quench thirst, and quenches one's thirst for lung, stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior heat. | Hypoglycemic and cardiotonic. | This medicine is 4 pages of Pharmacopoeia of the People's Republic of China P6, in January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P237, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor. |
| Caulis bambusae in taenian | The cane stem of Qiao Benke plant bambusa breviflora Munro Bambusa tuldoiefes Munro is used as medicine | Sweet, be slightly cold, attach to the lung and stomach meridians | Clearing heat and eliminating phlegm relieves restlessness and prevents vomiting, and holds phlegm, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, apoplexy phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pernicious vomiting fetal irritability under the arm for phlegm-heat cough, courage fire | This medicine is 07 page of Pharmacopoeia of the People's Republic of China P1, in January, 2000 front page, Chemical Industry Press, Chinese Pharmacopoeia Commission compiles. " traditional Chinese medicine " P196, in January, 1980 front page, People's Health Publisher's Hebei Medical College chief editor. |
Clinical drug application result of the present invention shows that following advantage is arranged:
1, to select pure Chinese medicine be raw material in the present invention, and each component meets the pharmaceutical control law regulation. Utilize the comprehensive function treatment of allergic rhinitis of the Chinese medicine of respectively distinguishing the flavor of, be pure Chinese medicinal preparation, nontoxic to human body, taking convenience.
2, the present invention regulates the immunity of body, and result for the treatment of is obvious, and can alleviate significantly or eliminate other complication, such as anaphylaxis pharyngitis, anaphylaxis laryngitis, allergic asthma, catarrhal otitis media etc.
3, the present invention treats both principal and secondary aspect of disease, and can replace all kinds of nasal drop, aerosol, histamine H1Receptor antagonist and vasoconstrictor etc., with desensitization therapy and the operative treatment comparison of modern medicine, the method is comparatively convenient.
Clinical drug observation of curative effect of the present invention:
Western medicines in treatment Comparison of therapeutic table
| Medicament categories | Sneeze | Rhinorrhea | Nasal obstruction | Anodimia | Myxedema | The EC |
| Decongestant | + + + | + | Sun | |||
| Antithistamine | + + + | + + | + | Sun | ||
| Different atropine | + + | Sun | ||||
| The nose cortin | + + + | + + | + + | + | + + | Sun |
| The whole body cortin | + + | + + | + + + | + + | + | Sun |
| Chinese medicine | + + + | + + + | + + + | + + | + + + | Cloudy |
Adopt diagnosis of allergic rhinitis standard and the efficacy assessment standard of national nasology art meeting revision in 1997, carry out at twice efficacy evaluation, short term effect carries out after finishing the course for the treatment of, and late result was carried out in treatment in rear 1 year. Since 1993, this prescription treatment of allergic rhinitis 500 examples have been adopted, after a course of therapy, clinical examination short term effect: produce effects 440 examples, effective 15 examples, invalid 45 examples, there are 420 examples to follow up a case by regular visits to 1 year in total effective rate 91%, 500 example, and again carry out efficacy evaluation, produce effects 256 examples, effective 114 examples, invalid 50 examples, total effective rate 88.14%, eosinophil checks positive 410 examples, negative 90 examples before the treatment, 385 examples transfer feminine gender to by the positive, negative conversion rate 93.92% after the treatment.
Claims (5)
1, a kind of medicine for the treatment of of allergic rhinitis is characterized in that it is the medicament of being made by the raw material of following weight proportioning:
Achene of Siberian cocklebur 6-20 part flower bud of lily magnolia 6-20 part root of Dahurain angelica 6-20 part
Chinese ephedra 3-10 part coix seed 6-20 part lily 6-20 part
Radix polygonati officinalis 5-15 part caulis bambusae in taenian 5-15 part cicada slough 6-20 part
Radix Glycyrrhizae 3-10 part
2, the medicine for the treatment of of allergic rhinitis according to claim 1, wherein the weight proportion of each raw material is:
Achene of Siberian cocklebur 6-15 part flower bud of lily magnolia 6-15 part root of Dahurain angelica 6-15 part
Chinese ephedra 3-9 part coix seed 6-15 part lily 6-15 part
Radix polygonati officinalis 5-10 part caulis bambusae in taenian 5-10 part cicada slough 6-15 part
Radix Glycyrrhizae 3-8 part
3, the medicine of described treatment of allergic rhinitis according to claim 1, wherein the weight proportion of each raw material is:
12 parts of 12 parts of roots of Dahurain angelica of 12 parts of flower buds of lily magnolia of the achene of Siberian cocklebur
12 parts of 12 portions of lilies of 6 parts of coix seeds of Chinese ephedra
12 parts of 10 portions of cicada sloughs of 10 parts of caulis bambusae in taenians of radix polygonati officinalis
6 parts in Radix Glycyrrhizae
4, according to claim 1, the medicine of 2 or 3 described treatment of allergic rhinitis, be characterised in that wherein said medicament is said formulation on any pharmacy.
5, the medicine for the treatment of of allergic rhinitis according to claim 4 is characterized in that said medicament is powder, honey pill agent, piece agent or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00129396 CN1300605A (en) | 2000-12-11 | 2000-12-11 | Medicine for treating allergic rhinitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00129396 CN1300605A (en) | 2000-12-11 | 2000-12-11 | Medicine for treating allergic rhinitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1300605A true CN1300605A (en) | 2001-06-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00129396 Pending CN1300605A (en) | 2000-12-11 | 2000-12-11 | Medicine for treating allergic rhinitis |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204546B (en) * | 2007-12-13 | 2010-12-15 | 骆金根 | Chinese traditional medicine preparation for allergic rhinitis |
| CN102178923A (en) * | 2011-05-05 | 2011-09-14 | 苏士峥 | Preparation method of traditional Chinese medicament for treating swelling tympanitis in external auditory meatus |
| CN102526546A (en) * | 2012-01-04 | 2012-07-04 | 田胜利 | Chinese medicinal composition and preparation and preparation method thereof |
| CN102895429A (en) * | 2012-11-08 | 2013-01-30 | 徐飞 | Chinese herbal medicine composition for treating allergic rhinitis and method for preparing Chinese herbal medicine composition for treating allergic rhinitis |
| CN102908418A (en) * | 2012-09-28 | 2013-02-06 | 陈文中 | Traditional Chinese medicine for treating anaphylactic rhinitis |
| WO2016183784A1 (en) * | 2015-05-18 | 2016-11-24 | 张甘霖 | Traditional chinese medicine for treating allergic rhinitis |
-
2000
- 2000-12-11 CN CN 00129396 patent/CN1300605A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204546B (en) * | 2007-12-13 | 2010-12-15 | 骆金根 | Chinese traditional medicine preparation for allergic rhinitis |
| CN102178923A (en) * | 2011-05-05 | 2011-09-14 | 苏士峥 | Preparation method of traditional Chinese medicament for treating swelling tympanitis in external auditory meatus |
| CN102178923B (en) * | 2011-05-05 | 2012-07-18 | 索贞 | Preparation method of traditional Chinese medicament for treating swelling tympanitis in external auditory meatus |
| CN102526546A (en) * | 2012-01-04 | 2012-07-04 | 田胜利 | Chinese medicinal composition and preparation and preparation method thereof |
| CN102908418A (en) * | 2012-09-28 | 2013-02-06 | 陈文中 | Traditional Chinese medicine for treating anaphylactic rhinitis |
| CN102908418B (en) * | 2012-09-28 | 2015-04-29 | 陈文忠 | Traditional Chinese medicine for treating anaphylactic rhinitis |
| CN102895429A (en) * | 2012-11-08 | 2013-01-30 | 徐飞 | Chinese herbal medicine composition for treating allergic rhinitis and method for preparing Chinese herbal medicine composition for treating allergic rhinitis |
| CN102895429B (en) * | 2012-11-08 | 2014-07-02 | 徐飞 | Chinese herbal medicine composition for treating allergic rhinitis and method for preparing Chinese herbal medicine composition for treating allergic rhinitis |
| WO2016183784A1 (en) * | 2015-05-18 | 2016-11-24 | 张甘霖 | Traditional chinese medicine for treating allergic rhinitis |
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