CN1295851A - Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof - Google Patents
Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof Download PDFInfo
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- CN1295851A CN1295851A CN 99115914 CN99115914A CN1295851A CN 1295851 A CN1295851 A CN 1295851A CN 99115914 CN99115914 CN 99115914 CN 99115914 A CN99115914 A CN 99115914A CN 1295851 A CN1295851 A CN 1295851A
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Abstract
A medicinal composition for curing cholecystitis and cholecystolithiasis is made up by using the following raw materials of artemisia stricta and/or dracocephalum tanguticum, moneywort, curcuma tuber, rheum tanguticum, gardenia fruit, inula racemosa, scutellaria root, lygodium spore and licorice according to the conventional preparation method. Said invention possesses the functions of coursing liver, disinhibiting gallbladder, loosening chest, rectifying qi, resolving tetany, relieving pain and dispelling stasis and discharging stone. Its effective rate can be up to 100%, and its cure rate can be up to above 90%.
Description
The present invention relates to a kind of serves as the main treatment cholecystitis of making and pharmaceutical composition of calculus and preparation method thereof with natural Tibetan medicine and Chinese herbal medicine.
Cholecystitis and calculosis are one of high morbidity and clinical common acute abdomen, it is generally acknowledged that cholestasis, biliary tract infection and cholesterol metabolism imbalance are the main causes of morbidity.Chronic cholecystitis can be brought out cholelithiasis, and cholelithiasis can bring out cholecystitis again, and there is reciprocal causation simultaneously in both.Its pathological symptom shows as: gallbladder-distention, costalgia mostly are that smooth, the cold temperature of emotion is uncomfortable, unhygienic diet or malnutrition due to parasitic infestation and cause QI stagnation of the liver and galibladder, damp and hot silt resistance.At present, be that the compound preparation of main treatment cholecystitis is more with the Chinese herbal medicine, but great majority are main compatibility agent with Radix Curcumae, Fructus Gardeniae or its rhizome, the Radix Aucklandiae, Radix Scutellariae, Spora Lygodii.Its curative effect is not ideal.
To the objective of the invention is that a kind of tool 'Shugan Lidan ', the chest stuffiness relieving are regulated the flow of vital energy in order providing, relieving spasm to stop pain, to separate silt calculus function, cure rate and can reach the treatment cholecystitis more than 90% and the pharmaceutical composition of calculus.
The present invention also aims to provide a kind of preparation of drug combination method for the treatment of cholecystitis and calculus.
Purpose of the present invention can realize by following measure:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: hide because of old and/or Herba Dracocephali tangutici 1-99%, Herba Lysimachiae and/or Rheum tanguticum 1-99%, Radix Curcumae 0-20%, Fructus Gardeniae 0-20%, Radix Inulae 0-20%, Radix Scutellariae 0-20%, Spora Lygodii 0-20%, Radix Glycyrrhizae 0-10%.Described ZANGYINCHEN is west, river Herba Swertiae bimaculatae, newspaper stem Herba Swertiae bimaculatae.
Purpose of the present invention also can realize by following measure:
A kind of preparation of drug combination method for the treatment of cholecystitis and calculus comprises the steps: 1. will hide and adopts conventional alcohol extraction process because of old, Herba Dracocephali tangutici, Herba Lysimachiae, Radix Curcumae, Rheum tanguticum, Fructus Gardeniae, Radix Inulae, Radix Scutellariae, Spora Lygodii, Radix Glycyrrhizae and extract; 2. extracting solution being transferred pH value is 5-7, again alcohol extract is crossed macroporous adsorbent resin; With the eluent recovered alcohol after conventional formulation technology is made medicament; 3. also can directly press after the alcohol extract slagging-off of the 1st step, routinely the preparation process preparation.
A kind of preparation of drug combination method for the treatment of cholecystitis and calculus comprises the steps: 1. will hide and adopts conventional extraction process by water because of old, Herba Dracocephali tangutici, Herba Lysimachiae, Radix Curcumae, Rheum tanguticum, Fructus Gardeniae, Radix Inulae, Radix Scutellariae, Spora Lygodii, Radix Glycyrrhizae and extract; 2. extracting solution being transferred pH value is 5-7, again the water extract is crossed the macroporous adsorbent resin bed; Discard the water of flushing then behind the water rinse resin bed of doubly measuring with the 2-5 of resin volume; 3. the adsorbate on the ethanol eluting macroporous adsorbent resin bed of the 60-80% that doubly measures of the 2-3 of reuse resin volume, with the eluent recovered alcohol after conventional formulation technology is made medicament; 4. also can be directly with after the water extract slagging-off of the 1st step, preparation process preparation routinely.
The present invention has following advantage compared to existing technology:
1, the present invention utilizes its active ingredient oleanolic acid and Mengiferin to reach functions such as clearing heat secreting bile, pain relieving calculus to hide because of old and/or Herba Dracocephali tangutici, Herba Lysimachiae and/or Rheum tanguticum.
2, also can add Radix Curcumae, Fructus Gardeniae, Radix Inulae, Radix Scutellariae, Spora Lygodii, Radix Glycyrrhizae etc. in the compatibility of the present invention; Make that the present invention has that 'Shugan Lidan ', the chest stuffiness relieving are regulated the flow of vital energy, relieving spasm to stop pain, the effect of separating the silt calculus, confirm that through clinical nearly hundred example tests effective percentage of the present invention can reach 100%, cure rate reaches more than 90%.
The present invention also will be described in further detail in conjunction with the embodiments:
Embodiment one:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: west, river Herba Swertiae bimaculatae 99%, Herba Lysimachiae 1%.
A kind of preparation of drug combination method for the treatment of cholecystitis and calculus comprises the steps: 1. to adopt conventional alcohol extraction process to extract west, river Herba Swertiae bimaculatae, Herba Lysimachiae; 2. extracting solution being transferred pH value is 6, again alcohol extract is crossed macroporous adsorbent resin; With the eluent recovered alcohol after conventional formulation technology is made medicament; 3. also can be directly with after the alcohol extract slagging-off of the 1st step, preparation process preparation routinely; Preparation is quality control standard with the oleanolic acid.
Embodiment two:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: newspaper stem Herba Swertiae bimaculatae 50%, Herba Lysimachiae 50%.
A kind of preparation of drug combination method for the treatment of cholecystitis and calculus comprises the steps: 1. will report stem Herba Swertiae bimaculatae, Herba Lysimachiae to adopt conventional extraction process by water to extract; 2. extracting solution being transferred pH value is 7, again the water extract is crossed the macroporous adsorbent resin bed; Discard the water of flushing then behind the water rinse resin bed with 4 times of amounts of resin volume; 3. the adsorbate on 70% of 2 of reuse resin volume times of amounts the ethanol eluting macroporous adsorbent resin bed, with the eluent recovered alcohol after conventional formulation technology is made medicament; 4. also can be directly with after the water extract slagging-off of the 1st step, preparation process preparation routinely; Preparation is quality control standard with the oleanolic acid.
Embodiment three:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: newspaper stem Herba Swertiae bimaculatae 40%, Herba Dracocephali tangutici 40%, Rheum tanguticum 20%.
Its preparation method and example one, two are together.
Embodiment four:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: west, river Herba Swertiae bimaculatae 10%, Herba Dracocephali tangutici 50%, Herba Lysimachiae 40%.
Its preparation method and example one, two are together.
Embodiment five:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: west, river Herba Swertiae bimaculatae 1%, Herba Dracocephali tangutici 1%, Herba Lysimachiae 78%, Radix Curcumae 10%, Rheum tanguticum 10%.
Its preparation method and example one, two are together.
Embodiment six:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: newspaper stem Herba Swertiae bimaculatae 12%, Herba Dracocephali tangutici 12%, Herba Lysimachiae 10%, Radix Curcumae 5%, Rheum tanguticum 15%, Fructus Gardeniae 20%, Radix Inulae 20%, Radix Scutellariae 6%.
Its preparation method and example one, two are together.
Embodiment seven:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: newspaper stem Herba Swertiae bimaculatae 70%, Herba Lysimachiae 5%, Fructus Gardeniae 5%, Radix Inulae 1%, Radix Scutellariae 5%, Spora Lygodii 7%, Radix Glycyrrhizae 7%.
Its preparation method and example one, two are together.
Embodiment eight:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: west, river Herba Swertiae bimaculatae 20%, Herba Dracocephali tangutici 20%, Herba Lysimachiae 15%, Radix Curcumae 1%, Rheum tanguticum 15%, Fructus Gardeniae 10%, Radix Inulae 5%, Radix Scutellariae 1%, Spora Lygodii 12%, Radix Glycyrrhizae 1%.
Its preparation method and example one, two are together.
Embodiment nine:
A kind of pharmaceutical composition for the treatment of cholecystitis and calculus by comprise following raw materials in percentage by weight routinely formulation method make: Herba Dracocephali tangutici 30%, Herba Lysimachiae 5%, Radix Curcumae 20%, Rheum tanguticum 15%, Fructus Gardeniae 10%, Radix Inulae 5%, Radix Scutellariae 10%, Spora Lygodii 5%.
Its preparation method and example one, two are together.
Claims (4)
1, a kind of pharmaceutical composition for the treatment of cholecystitis and calculus, it is characterized in that by comprise following raw materials in percentage by weight routinely formulation method make: hide because of old and/or Herba Dracocephali tangutici 1-99%, Herba Lysimachiae and/or Rheum tanguticum 1-99%, Radix Curcumae 0-20%, Fructus Gardeniae 0-20%, Radix Inulae 0-20%, Radix Scutellariae 0-20%, Spora Lygodii 0-20%, Radix Glycyrrhizae 0-10%.
2, the pharmaceutical composition of treatment cholecystitis as claimed in claim 1 and calculus, it is characterized in that described medicament be any pharmaceutics the above dosage form.
3, a kind of preparation of drug combination method for the treatment of cholecystitis and calculus is characterized in that comprising the steps: 1. will hiding and adopts conventional alcohol extraction process because of old, Herba Dracocephali tangutici, Herba Lysimachiae, Radix Curcumae, Rheum tanguticum, Fructus Gardeniae, Radix Inulae, Radix Scutellariae, Spora Lygodii, Radix Glycyrrhizae and extract; 2. extracting solution being transferred pH value is 5-7, again alcohol extract is crossed macroporous adsorbent resin; With the eluent recovered alcohol after conventional formulation technology is made medicament; 3. also can be directly with after the alcohol extract slagging-off of the 1st step, preparation process preparation routinely.
4, a kind of preparation of drug combination method for the treatment of cholecystitis and calculus is characterized in that comprising the steps: 1. will hiding and adopts conventional extraction process by water because of old, Herba Dracocephali tangutici, Herba Lysimachiae, Radix Curcumae, Rheum tanguticum, Fructus Gardeniae, Radix Inulae, Radix Scutellariae, Spora Lygodii, Radix Glycyrrhizae and extract; 2. extracting solution being transferred pH value is 5-7, again the water extract is crossed the macroporous adsorbent resin bed; Discard the water of flushing then behind the water rinse resin bed of doubly measuring with the 2-5 of resin volume; 3. the adsorbate on the ethanol eluting macroporous adsorbent resin bed of the 60-80% that doubly measures of the 2-3 of reuse resin volume, with the eluent recovered alcohol after conventional formulation technology is made medicament; 4. also can be directly with after the water extract slagging-off of the 1st step, preparation process preparation routinely.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99115914 CN1295851A (en) | 1999-11-11 | 1999-11-11 | Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99115914 CN1295851A (en) | 1999-11-11 | 1999-11-11 | Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof |
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| CN1295851A true CN1295851A (en) | 2001-05-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 99115914 Pending CN1295851A (en) | 1999-11-11 | 1999-11-11 | Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045116B (en) * | 2007-04-18 | 2010-05-26 | 孙晓波 | Traditional Chinese medicine for treating cholecystitis |
| CN103393909A (en) * | 2013-07-20 | 2013-11-20 | 李兴达 | Chinese medicinal preparation for treating biliary calculus with cholecystitis |
| CN104887963A (en) * | 2015-05-09 | 2015-09-09 | 甄国栋 | Traditional Chinese medicine preparation used for gallbladder postoperative rehabilitation |
| CN108186725A (en) * | 2018-02-07 | 2018-06-22 | 西藏月王藏药科技有限公司 | A kind of Herba Dracocephali Tangutici Tibetan medicine medicine materical crude slice and its concocting method |
-
1999
- 1999-11-11 CN CN 99115914 patent/CN1295851A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045116B (en) * | 2007-04-18 | 2010-05-26 | 孙晓波 | Traditional Chinese medicine for treating cholecystitis |
| CN103393909A (en) * | 2013-07-20 | 2013-11-20 | 李兴达 | Chinese medicinal preparation for treating biliary calculus with cholecystitis |
| CN104887963A (en) * | 2015-05-09 | 2015-09-09 | 甄国栋 | Traditional Chinese medicine preparation used for gallbladder postoperative rehabilitation |
| CN108186725A (en) * | 2018-02-07 | 2018-06-22 | 西藏月王藏药科技有限公司 | A kind of Herba Dracocephali Tangutici Tibetan medicine medicine materical crude slice and its concocting method |
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