CN103393909A - Chinese medicinal preparation for treating biliary calculus with cholecystitis - Google Patents
Chinese medicinal preparation for treating biliary calculus with cholecystitis Download PDFInfo
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- CN103393909A CN103393909A CN2013103209353A CN201310320935A CN103393909A CN 103393909 A CN103393909 A CN 103393909A CN 2013103209353 A CN2013103209353 A CN 2013103209353A CN 201310320935 A CN201310320935 A CN 201310320935A CN 103393909 A CN103393909 A CN 103393909A
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- cholecystitis
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 201000001352 cholecystitis Diseases 0.000 title claims abstract description 13
- 239000003814 drug Substances 0.000 claims description 21
- 201000001883 cholelithiasis Diseases 0.000 claims description 12
- 241000903946 Clematidis Species 0.000 claims description 9
- 210000000232 gallbladder Anatomy 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 6
- 210000004185 liver Anatomy 0.000 abstract description 4
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 3
- 210000000941 bile Anatomy 0.000 abstract description 2
- 239000004575 stone Substances 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 241000304531 Allium macrostemon Species 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 241000218158 Clematis Species 0.000 abstract 1
- 241000570861 Mandragora autumnalis Species 0.000 abstract 1
- 240000005859 Orthosiphon aristatus Species 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 241000395057 Swertia yunnanensis Species 0.000 abstract 1
- 241000219873 Vicia Species 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000003950 pathogenic mechanism Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000008828 contractile function Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 206010008616 Cholecystitis and cholelithiasis Diseases 0.000 description 1
- 208000002513 Flank pain Diseases 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000000387 litholytic effect Effects 0.000 description 1
- 238000007449 liver function test Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
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- 231100000614 poison Toxicity 0.000 description 1
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- 230000033764 rhythmic process Effects 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 239000008812 xiaoyanlidan Substances 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese medicinal preparation for treating biliary calculus with cholecystitis. Traditional Chinese doctors believe that the pathogenic mechanisms of the biliary calculus with cholecystitis are liver and gall dysfunction, bile blockage, drainage difficulty, gallbladder blockage and stone accumulation. Thus, traditional Chinese medicines such as swertia yunnanensis burkill, orthosiphon aristatus, vetch, narrowleaf fig root and leaf, whiteflower violet herb with root, root of caulescent mandrake, green tangerine peel, allium macrostemon, henry clematis root and rhubarb are selected and decocted into medicinal broth with water in a preparation room of the hospital; and clinical tests prove that the total effectiveness ratio reaches 98.5 percent and is obviously superior to that of a control group and the Chinese medicinal preparation has a good clinical promotion effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of cholelithiasis and cholecystitis.
Background technology
Cholelithiasis and cholecystitis are common clinical, frequently-occurring disease, Relapse rate outbreak, and protracted course of disease, clinical manifestation is without specificity, commonly right upper quadrant of the abdomen or precordial region dull pain, glutted discomfort after food, belch, can have nauseatingly after the feed greasy food, vomiting is occasionally arranged; The present oral litholytic therapy of Western medicine, be only applicable to the cholesterol calculus of gallbladder, must be after reaching 1～2 year take continuously, and only approximately 20% patient's cholelithiasis disappears.The dissolved stone medicine side effect is large, and after expensive and drug withdrawal, relapse rate is high.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of cholelithiasis and cholecystitis.The traditional Chinese medical science thinks that feelings will is uncomfortable, eating and drinking without temperance, and being invaded by exogenous pathogen, infecting malnutrition due to parasitic infestation is cholelithiasis and cholecystitis main pathogenic.Sick position, mainly at liver, gallbladder, relates to spleen, large intestine.Pathogeny is that the liver and gall mistake is dredged, the bile retardance, and drainage difficulty, the gallbladder internal organs is obstructed, pents up calculogenesis.
The objective of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment cholelithiasis and cholecystitis is made by the Chinese medicine of following weight portion: Herba Swertiae yunnanensis 15-20 part, Herba clerodendranthi spicati 20-30 part, Herba Viviae Sativae 5-10 part, Radix Fici Angustipoliae 14-22 part, Herba violae patrinii 15-25 part, Radix mandragorae caulescentis 1-3 part, Pericarpium Citri Reticulatae Viride 13-17 part, Bulbus Allii Macrostemonis 11-16 part, Radix Clematidis Henryi 9-13 part, Radix Et Rhizoma Rhei 10-15 part.
Preferably, 18 parts of Herba Swertiae yunnanensiss, 25 parts of Herba clerodendranthi spicati, 7 parts of Herba Viviae Sativaes, 19 parts of Radix Fici Angustipoliae, 20 parts of Herba violae patriniis, 1.5 parts of Radix mandragorae caulescentiss, 15 parts, Pericarpium Citri Reticulatae Viride, 14 parts of Bulbus Allii Macrostemonis, 11 parts of Radix Clematidis Henryi, 13 parts of Radix Et Rhizoma Rhei.
Preparation method is made decoction with above-mentioned Chinese medicine decocting.
In side: Herba Swertiae yunnanensis, Herba clerodendranthi spicati, Herba Viviae Sativae liver heat removing function of gallbladder promoting, clearing heat and expelling damp, calculus diuretic, blood circulation promoting and blood stasis dispelling; Radix Fici Angustipoliae, Herba violae patrinii, Radix mandragorae caulescentis heat-clearing and toxic substances removing, expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling, warming spleen and stomach for dispelling cold, resolving depression pain relieving; Pericarpium Citri Reticulatae Viride, Bulbus Allii Macrostemonis, Radix Clematidis Henryi depressed liver-energy dispersing and QI regulating, removing food stagnancyization is stagnant, activating YANG and eliminating stagnation, promoting flow of QI and blood, anti-inflammation; The Radix Et Rhizoma Rhei heat and toxic materials clearing away, clearing away heat-fire, hemostasis detoxifcation.
Clinical data
1, the routine patient of this group of physical data 128 is diagnosed as the cholelithiasis cholecystitis through clinical and iconography, is divided at random treatment group and matched group.Treatment group 68 examples, male 28 examples wherein, female's 40 examples; 35～45 years old age, 36 examples, 45～55 years old 20 example, 55～65 years old 12 example.5 months～1 year 34 examples of the course of disease, 38 examples more than 1 year.Matched group 60 examples, male 20 examples wherein, female's 40 examples; 36～48 years old age, 32 examples, 48～55 years old 16 example, 55～70 years old 12 example, 6 months～1.5 years 24 examples of the course of disease, 36 examples more than 1.5 years.Two groups of patients compare aspect sex, age, the course of disease, no significant difference (P＞0.05), have comparability.
2, diagnostic criteria right side side of body flank pain is radiated to the shoulder back, and uncomfortable in chest, the gastral cavity abdomen is glutted, nausea and vomiting, and poor appetite is weak, bitter taste, yellowish or reddish urine, how above-mentioned symptom recurrence or increase the weight of the emotion irritability after tired, anger or greasy, the cool food of surfeit plumpness.Ultrasound diagnosis: cholelithiasis is many between 0.3～0.5cm, thickening of capsule wall of gallbladder.Crude.Liver function test: normal.
3, the Therapeutic Method treatment group is taken Chinese medicine preparation of the present invention, take Herba Swertiae yunnanensis 18g, Herba clerodendranthi spicati 25g, Herba Viviae Sativae 7g, Radix Fici Angustipoliae 19g, Herba violae patrinii 20g, Radix mandragorae caulescentis 1.5g, Pericarpium Citri Reticulatae Viride 15g, Radix Et Rhizoma Rhei 13g, decocting becomes decoction, and potion, divided sooner or later and took for 2 times every day; Matched group give XIAOYAN LIDAN PIAN (Mt.Luofushan traditional Chinese medicines limited company, the accurate word of traditional Chinese medicines: Z44021442) each 6, every day 3 times, warm water is oral ante cibum, two groups of equal 2 weeks are a course for the treatment of.
4, criterion of therapeutical effect is cured: clinical symptoms, sign disappear fully, discharge calculus or discharge 75% calculus before treatment; Confirm that through B ultrasonic calculus disappears, it is normal that gallbladder wall and contractile function recover, and follows up a case by regular visits to and do not recur half a year.Produce effects: symptom, sign disappear substantially, through B ultrasonic, confirm the discharge section calculus, and gallbladder wall and contractile function obviously improve.Effectively: symptom, sign are obviously improved, without calculus.Invalid: symptom, sign, calculus are without improvement.
5, after two groups of therapeutic outcomes treatment course for the treatment of curative effect relatively, treatment group 68 examples, wherein cure 46 examples (67.6%); Produce effects 13 examples (19.1%), effective 8 examples (11.8%), invalid 1 example (1.5%), total effective rate 98.5%; Matched group 60 examples, wherein cure 26 examples (43.3%); Produce effects 13 examples (21.7%), effective 10 examples (16.7%), invalid 11 examples (18.3%), total effective rate 81.7%.Two groups relatively, and treatment group cure rate, total effective rate obviously are better than matched group, have comparability.P＜0.05。
6, model case patient, man, 50 years old.January 30 nineteen ninety-five, because of precordial region pain, heating fear of cold, jaundice and hospitalize and be admitted to hospital.Original cholecystitis and cholelithiasis 7 years, outbreak repeatedly.Nearly state of an illness aggravation in March.Look into: T39 ℃, BP14.6/9.3kpa, R18 time/minute.Conscious, pale complexion is simple and unadorned, yellow sclera, and heart rate 85 times/minutes, the rhythm of the heart is neat, and without the pathologic noise, lung is examined (-), right upper quadrant of the abdomen tenderness (+), the little jaundice of breast Pericarpium Arecae skin, lower abdomen is soft, without tenderness, nervous system ().B ultrasonic prompting: cholelithiasis cholecystitis, calculus size 2cm * 3cm * 1.5cm.Blood routine examination: leukocyte 21 * 109/L.First with Western medicine transfusion, anti-inflammation, pain management repeatedly.Took Chinese medicine decoction of the present invention to February 1, prescription: Herba Swertiae yunnanensis 18g, Herba clerodendranthi spicati 25g, Herba Viviae Sativae 7g, Radix Fici Angustipoliae 19g, Herba violae patrinii 20g, Radix mandragorae caulescentis 1.5g, Pericarpium Citri Reticulatae Viride 15g, Bulbus Allii Macrostemonis 14g, Radix Clematidis Henryi 11g, Radix Et Rhizoma Rhei 13g.To taking the 5th dose, the patient when defecating, discharges big or small 3cm * 2cm * 1 piece, 1.5cm calculus, and symptom also takes a turn for the better thereupon, 5 years so far, has no recurrence.
The specific embodiment
Embodiment one: take Herba Swertiae yunnanensis 18g, Herba clerodendranthi spicati 25g, Herba Viviae Sativae 7g, Radix Fici Angustipoliae 19g, Herba violae patrinii 20g, Radix mandragorae caulescentis 1.5g, Pericarpium Citri Reticulatae Viride 15g, Bulbus Allii Macrostemonis 14g, Radix Clematidis Henryi 11g, Radix Et Rhizoma Rhei 13g, above-mentioned Chinese medicine decocting is made decoction.
Embodiment two: take Herba Swertiae yunnanensis 20g, Herba clerodendranthi spicati 30g, Herba Viviae Sativae 5g, Radix Fici Angustipoliae 14g, Herba violae patrinii 25g, Radix mandragorae caulescentis 3g, Pericarpium Citri Reticulatae Viride 17g, Bulbus Allii Macrostemonis 16g, Radix Clematidis Henryi 9g, Radix Et Rhizoma Rhei 10g, above-mentioned Chinese medicine decocting is made decoction.
Embodiment three: take Herba Swertiae yunnanensis 15g, Herba clerodendranthi spicati 20g, Herba Viviae Sativae 10, Radix Fici Angustipoliae 22g, Herba violae patrinii 15g, Radix mandragorae caulescentis 1g, Pericarpium Citri Reticulatae Viride 13g, Bulbus Allii Macrostemonis 11g, Radix Clematidis Henryi 13g, Radix Et Rhizoma Rhei 15g makes decoction with above-mentioned Chinese medicine decocting.
Claims (2)
1. Chinese medicine preparation for the treatment of cholelithiasis and cholecystitis, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Herba Swertiae yunnanensis 15-20 part, Herba clerodendranthi spicati 20-30 part, Herba Viviae Sativae 5-10 part, Radix Fici Angustipoliae 14-22 part, Herba violae patrinii 15-25 part, Radix mandragorae caulescentis 1-3 part, Pericarpium Citri Reticulatae Viride 13-17 part, Bulbus Allii Macrostemonis 11-16 part Radix Clematidis Henryi 9-13 part, Radix Et Rhizoma Rhei 10-15 part.
2. require 1 described a kind of Chinese medicine preparation for the treatment of cholelithiasis and cholecystitis according to claim, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 18 parts of Herba Swertiae yunnanensiss, 25 parts of Herba clerodendranthi spicati, 7 parts of Herba Viviae Sativaes, 19 parts of Radix Fici Angustipoliae, 20 parts of Herba violae patriniis, 1.5 parts of Radix mandragorae caulescentiss, 15 parts, Pericarpium Citri Reticulatae Viride, 14 parts of Bulbus Allii Macrostemonis, 11 parts of Radix Clematidis Henryi, 13 parts of Radix Et Rhizoma Rhei.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310320935.3A CN103393909B (en) | 2013-07-20 | 2013-07-20 | Chinese medicinal preparation for treating biliary calculus with cholecystitis |
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| CN201310320935.3A CN103393909B (en) | 2013-07-20 | 2013-07-20 | Chinese medicinal preparation for treating biliary calculus with cholecystitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887963A (en) * | 2015-05-09 | 2015-09-09 | 甄国栋 | Traditional Chinese medicine preparation used for gallbladder postoperative rehabilitation |
| CN105535863A (en) * | 2016-01-30 | 2016-05-04 | 王廷波 | Traditional Chinese medicine composition for treating cholelithiasis |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1295851A (en) * | 1999-11-11 | 2001-05-23 | 中国科学院西北高原生物研究所 | Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof |
| CN1954859A (en) * | 2005-10-26 | 2007-05-02 | 西乌珠穆沁旗蒙医医院 | Mongolia medicine composite for treating chronic cholecystitis, cholecystalgia and its method |
| CN102552798A (en) * | 2010-12-27 | 2012-07-11 | 广西中医学院 | Medicinal composition for treating cholelithiasis |
| CN102940740A (en) * | 2012-11-30 | 2013-02-27 | 宋华清 | Medicament for treating lithiasis and preparation method thereof |
-
2013
- 2013-07-20 CN CN201310320935.3A patent/CN103393909B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1295851A (en) * | 1999-11-11 | 2001-05-23 | 中国科学院西北高原生物研究所 | Medicinal composition for treating cholecystitis and cholecystolithiasis and preparation process thereof |
| CN1954859A (en) * | 2005-10-26 | 2007-05-02 | 西乌珠穆沁旗蒙医医院 | Mongolia medicine composite for treating chronic cholecystitis, cholecystalgia and its method |
| CN102552798A (en) * | 2010-12-27 | 2012-07-11 | 广西中医学院 | Medicinal composition for treating cholelithiasis |
| CN102940740A (en) * | 2012-11-30 | 2013-02-27 | 宋华清 | Medicament for treating lithiasis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 顾宏刚 等: "胆石病中医辨证论治进展", 《湖北中医学院学报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887963A (en) * | 2015-05-09 | 2015-09-09 | 甄国栋 | Traditional Chinese medicine preparation used for gallbladder postoperative rehabilitation |
| CN105535863A (en) * | 2016-01-30 | 2016-05-04 | 王廷波 | Traditional Chinese medicine composition for treating cholelithiasis |
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| CN103393909B (en) | 2014-10-22 |
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