CN1285209A - Medicine for treating peptic ulcer - Google Patents
Medicine for treating peptic ulcer Download PDFInfo
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- CN1285209A CN1285209A CN 99111600 CN99111600A CN1285209A CN 1285209 A CN1285209 A CN 1285209A CN 99111600 CN99111600 CN 99111600 CN 99111600 A CN99111600 A CN 99111600A CN 1285209 A CN1285209 A CN 1285209A
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Abstract
The present invention relates to a kind of medicine for curing peptic ulcer, and is characterized by that (by weight portion) 10-15 portions of astragalus root, 9-20 portions of white peony root, 9-12 portions of bletilla tube, 8-12 portions of prepared licorice, 9-15 portions of tangerine pell, 9-15 portions of cuttlefish bone, 25-30 portions of dandelion, 9-12 portions of cinnamon twig, 6-9 portions of lesser galangal root and 6-9 portions of cyperus root are pulverized to obtain fine powder with 120 meshes, then said obtained fine powder and 15-20 portions of yannan white are mixed to obtain Chinese patent medicine powder or a proper quantity of loney can be added into the above-mentioned powder preparation and made into pill preparation, then the above-onentioned Chinese patent medicine can be combined with 24 tablets of furazolidone for oral medication.
Description
The present invention relates to a kind of Chinese and Western bound drug, relate in particular to a kind of medicine for the treatment of peptic ulcer.
Gastropathy is a kind of clinical common frequently-occurring disease, especially peptic ulcer, belongs to a kind of of frequently-occurring disease in China, also belongs to all over the world and seeing more.Study statistics according to the relevant person: " in people's life course, having the people of 5%-10% can suffer from digestion approximately must ulcer." primary disease can betide the people of any age bracket, wherein see with the person between twenty and fifty and the middle age in 20-50 year especially more.The recurrence easily of primary disease healing back, if state of an illness evolution, then symptom can day by day increase the weight of, and can cause gastrorrhagia or gastric perforation.Therefore, it is the disease of a kind of serious harm health of people and life.
At present, the Drug therapy of peptic ulcer can make this patient more than 95% avoid surgical operation.But the recurrence after the drug withdrawal is still a difficult problem extremely to be solved.Name is called the 131st page of the 3rd phase of in JIUYUE, 1996 Volume Four of " Chinese combination of Chinese and Western medicine taste magazine " and goes up report: " the curative effect of therapy of combining Chinese and Western medicine peptic ulcer; ulcer healing rate is 50%-80%; relapse rate 11%-19% in the relapse rate 6.25%, a year in half a year.The ulcer healing rate 70%-80% in Western medicine 4-8 week, cimetidine 4 all regular treatments, the relapse rate 60%-80% that heals later six months, healing back maintenance dose, relapse rate still has 15%-20% in half a year.”
At present, existing another problem of the Drug therapy of peptic ulcer is that the course of treatment is long, general in, course of treatment of Western medicine is all more than 28 days.
The objective of the invention is to overcome above-mentioned deficiency and a kind of medicine for the treatment of peptic ulcer is provided, this medicine is by the spleen invigorating warming middle-JIAO, assistant with promoting flow of QI and blood to improve the gastric mucosa circumfusion, suppress helicobacter pylori infections, it is synthetic to increase the gastric mucosa prostaglandin, strengthens the gastric mucosal barrier function, thereby reaches rapid healing ulcer, improve the ulcer healing quality, and prevent the purpose of ulcer recurrence.
Technical scheme of the present invention is based on the understanding of the basic demand that peptic ulcer is taken place; promptly stomach, duodenum local mucous membrane damage factor are strengthened; or the understanding that weakens of mucous membrane protection factor; adopt the method treatment peptic ulcer of the combination of Chinese and Western medicine; both emphasized dialectically, set about paying attention to debating disease, both combinations again from the part of ulcer from integral body; the ulcer that both can heal rapidly can prevent its late relapse again.
The medicine of treatment peptic ulcer of the present invention has following two kinds of dosage forms.
First kind of dosage form is a kind ofly to comprise that this 10 flavor Chinese medicine component of 10-15 part Radix Astragali, 9-20 part Radix Paeoniae Alba, 9-12 part Pseudobulbus Bletillae (Rhizoma Bletillae), 8-12 part Radix Glycyrrhizae Preparata, 9-15 part Pericarpium Citri Reticulatae, 9-15 part Os Sepiae, 25-30 part Herba Taraxaci, 9-12 part Ramulus Cinnamomi, 6-9 part Rhizoma Alpiniae Officinarum and 6-9 part Rhizoma Cyperi of meter is ground into 120 purpose fine powders by weight, again the Chinese herbal medicine powder that makes with 15-20 part YUNNAN BAIYAO mix homogeneously and 24 tablets of furazolidone Western medicine combine take in, the bonded medicine of Western medicine.
The ratio of each component is in first kind of described powder of dosage form: 12 parts of the Radixs Astragali, 12 parts of the Radix Paeoniae Albas, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 12 parts of Radix Glycyrrhizae Preparata, 10 parts of Pericarpium Citri Reticulataes, 12 parts of Os Sepiae, 25 parts of Herba Taraxacis, 9 parts of Ramulus Cinnamomi, 6 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Cyperis, 17.5 parts of YUNNAN BAIYAO.
Second kind of dosage form be a kind of Chinese patent medicine pill that powder described in first kind of dosage form is made with the proper honey mix homogeneously again and 24 tablets of furazolidone Western medicine combine take in, the bonded medicine of Western medicine.
The each component proportioning is in second kind of described powder of dosage form: 12 parts of the Radixs Astragali, 12 parts of the Radix Paeoniae Albas, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 12 parts of Radix Glycyrrhizae Preparata, 10 parts of Pericarpium Citri Reticulataes, 12 parts of Os Sepiae, 25 parts of Herba Taraxacis, 9 parts of Ramulus Cinnamomi, 6 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Cyperis, 17.5 parts of YUNNAN BAIYAO, described Mel is counted 131.5 parts by weight.
The pharmacological effect of medicine of the present invention is as follows:
Furazolidone disturbs oxidoreduction enzyme system in the bacterial body by it, makes the bacterial metabolism disorder, thereby suppresses the destruction of helicobacter pylori to gastrointestinal mucosa effectively, to eliminate the damage factor of stomach, duodenum local mucous membrane, reaches " eliminating evil ".
The Radix Astragali can blood vessel dilating, improves blood fortune, and non-viable non-apoptotic cell is brought back to life, and can prevent the generation of gastric ulcer due to the ligation pylorus.Radix Paeoniae is joined Radix Glycyrrhizae can remove the gastrointestinal smooth muscular spasm, and contained enoxolone can promote ulcer healing in the Radix Glycyrrhizae.Pericarpium Citri Reticulatae has antiulcer and antiinflammatory action.Pseudobulbus Bletillae (Rhizoma Bletillae) matter is sticking, makes gastric mucosa surface form protecting film behind the clothes, and has anastalsis.Os Sepiae can prevent acid to reduce the erosion of acidic gastric juice to gastrointestinal mucosa.Herba Taraxaci heat-clearing and toxic substances removing and digestion promoting function is arranged promotes the effectiveness of ulcer surface healing in addition.YUNNAN BAIYAO has the effect of blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting, styptic powder pain, and can significantly strengthen the phagocytic function of macrophage, and the links such as medium release, increased capillary permeability and leukoplania of inflammatory process are had inhibitory action.These all help the growth of wound and promote the healing of ulcer surface.The Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian.The Rhizoma Alpiniae Officinarum warming spleen and stomach for dispelling cold.The Rhizoma Cyperi resolving depression of regulating the flow of vital energy.This group medicine adapted has the defense reaction that strengthens gastrointestinal mucosa, reaches " setting upright ".
The advantage of medicine of the present invention is as follows:
1, prescription is simple, raw material is easy to get, production method is simple, with low cost.
2, dose is little, taking convenience.
3, cure rate height, relapse rate are low.Needn't avoid food after the healing, not occur having a relapse.
4, short treating period can reach ulcer a course of treatment (14 days) and disappear and the effect of rehabilitation.
The instructions of taking of medicine of the present invention:
The clothes furazolidone is 4 days earlier, obeys every day 3 times.Each clothes were 3 in first day; Each clothes were 2 in second day, the 3rd day; Each clothes were 1 in the 4th day, obeyed 24 altogether in 4 days.Connect Chinese herbal medicine powder or pill described in the clothes medicine of the present invention then, obey every day 3 times, obey the 6-9 gram at every turn, 14 days is a course of treatment.
For showing the therapeutic effect of medicine of the present invention to peptic ulcer, the present invention is through 100 routine clinical observations, and selects peptic ulcer patient 36 examples to be matched group at random.All cases are diagnosed as the patient of activeness stomach or duodenal ulcer, wherein male 72 examples, women 64 examples, the course of disease 3 months-20 years through fibergastroscope.
Therapeutic Method: matched group adopts tcm treatment according to syndrome differentiation, takes Zhang Zhongjing ancient prescription Huangqi Jianzhong Tang, one pair of day clothes, and 30 days is a course of treatment.The treatment group is taken medicine of the present invention, and 14 days is a course of treatment.After a course of therapy, the clinical efficacy result is as follows:
About 13.9% 31 86.1% (n=36) of 99 99% 1 1% 0000 100 100% (n=100) matched groups 25 about 69.5% 3 about 8.3% 3 about 83% 5 are organized in the invalid routine number % total effective rate example number % of the effective routine number % of the routine number % produce effects example number % treatment of fully recovering of stomach, duodenal ulcer
Treatment group and matched group patient are selected the follow-up observation that 20 examples have been carried out 2 years respectively, and matched group recurs 4 examples as a result, and relapse rate is 20%, and then no case was recurrence for the treatment group.
Above-mentioned clinical efficacy result shows: have short treating period (14 days), curative effect height, advantage that relapse rate is low with Drug therapy peptic ulcer of the present invention.
Medicine of the present invention also has significant curative effect except that peptic ulcer is had the specially good effect to asthenic cold type gastritis.
Embodiment
Take by weighing raw material by following proportioning:
12 kilograms of the Radixs Astragali, 12 kilograms of the Radix Paeoniae Albas, 10 kilograms of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 12 kilograms of Radix Glycyrrhizae Preparata, 10 kilograms of Pericarpium Citri Reticulataes, 12 kilograms of Os Sepiae, 25 kilograms of Herba Taraxacis, 9 kilograms of Ramulus Cinnamomi, 6 kilograms of Rhizoma Alpiniae Officinarums, 6 kilograms of Rhizoma Cyperis, 17.5 kilograms of YUNNAN BAIYAO.
Above-mentioned preceding 10 flavor Chinese medicine powders are broken into 120 order fine powders,, make the Chinese herbal medicine powder in the medicine of the present invention or with the Mel mf mass pil (honeyed pill) of this Chinese herbal medicine powder and 131.5 kilograms, every ball 10 restrains then with the YUNNAN BAIYAO mix homogeneously.
Claims (4)
1, a kind of medicine for the treatment of peptic ulcer, it is characterized in that: it be a kind of comprise will be by weight this 10 flavor Chinese medicine component of 10-15 part Radix Astragali, 9-20 part Radix Paeoniae Alba, 9-12 part Pseudobulbus Bletillae (Rhizoma Bletillae), 8-12 part Radix Glycyrrhizae Preparata, 9-15 part Pericarpium Citri Reticulatae, 9-15 part Os Sepiae, 25-30 part Herba Taraxaci, 9-12 part Ramulus Cinnamomi, 6-9 part Rhizoma Alpiniae Officinarum and 6-9 part Rhizoma Cyperi of meter be ground into 120 purpose fine powders, again the Chinese herbal medicine powder that makes with 15-20 part YUNNAN BAIYAO mix homogeneously and 24 tablets of furazolidone Western medicine combine take in, the bonded medicine of Western medicine.
2, the medicine of treatment peptic ulcer according to claim 1 is characterized in that: it be a kind of Chinese patent medicine pill that described Chinese herbal medicine powder is made with the proper honey mix homogeneously again and 24 tablets of furazolidone Western medicine combine take in, the bonded medicine of Western medicine.
3, the medicine of treatment peptic ulcer according to claim 1 is characterized in that: the proportioning of each component is in the described Chinese herbal medicine powder:
12 parts of the Radixs Astragali, 12 parts of the Radix Paeoniae Albas, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 12 parts of Radix Glycyrrhizae Preparata, 10 parts of Pericarpium Citri Reticulataes, 12 parts of Os Sepiae, 25 parts of Herba Taraxacis, 9 parts of Ramulus Cinnamomi, 6 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Cyperis, 17.5 parts of YUNNAN BAIYAO.
4, the medicine of treatment peptic ulcer according to claim 2 is characterized in that: the proportioning of each component is in the described Chinese patent medicine pill:
12 parts of the Radixs Astragali, 12 parts of the Radix Paeoniae Albas, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 12 parts of Radix Glycyrrhizae Preparata, 10 parts of Pericarpium Citri Reticulataes, 12 parts of Os Sepiae, 25 parts of Herba Taraxacis, 9 parts of Ramulus Cinnamomi, 6 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Cyperis, 17.5 parts and 131.5 parts Mel of YUNNAN BAIYAO.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99111600A CN1088592C (en) | 1999-08-20 | 1999-08-20 | Medicine for treating peptic ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99111600A CN1088592C (en) | 1999-08-20 | 1999-08-20 | Medicine for treating peptic ulcer |
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| Publication Number | Publication Date |
|---|---|
| CN1285209A true CN1285209A (en) | 2001-02-28 |
| CN1088592C CN1088592C (en) | 2002-08-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99111600A Expired - Fee Related CN1088592C (en) | 1999-08-20 | 1999-08-20 | Medicine for treating peptic ulcer |
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| Country | Link |
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| CN (1) | CN1088592C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793097A (en) * | 2012-09-08 | 2012-11-28 | 云南植物药业有限公司 | Health care food with gastric mucous membrane protecting function |
| CN104435731A (en) * | 2014-12-09 | 2015-03-25 | 卢旭鹏 | Oral medicine for treating stomach illness and preparation method thereof |
| CN104958462A (en) * | 2015-07-25 | 2015-10-07 | 王璐 | Traditional Chinese medicine for treating duodenal ulcer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110924A (en) * | 1994-04-28 | 1995-11-01 | 余慕良 | Effective drug for gastric disease |
| CN1188004A (en) * | 1997-01-17 | 1998-07-22 | 孙兆伟 | Gastrointestinal mucosa nutritive protective agent and its preparing technology |
-
1999
- 1999-08-20 CN CN99111600A patent/CN1088592C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793097A (en) * | 2012-09-08 | 2012-11-28 | 云南植物药业有限公司 | Health care food with gastric mucous membrane protecting function |
| CN104435731A (en) * | 2014-12-09 | 2015-03-25 | 卢旭鹏 | Oral medicine for treating stomach illness and preparation method thereof |
| CN104958462A (en) * | 2015-07-25 | 2015-10-07 | 王璐 | Traditional Chinese medicine for treating duodenal ulcer |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1088592C (en) | 2002-08-07 |
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