CN1279992A - Medicine for curing and preventing upper respiratory infection and its preparing method - Google Patents

Medicine for curing and preventing upper respiratory infection and its preparing method Download PDF

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CN1279992A
CN1279992A CN 99109553 CN99109553A CN1279992A CN 1279992 A CN1279992 A CN 1279992A CN 99109553 CN99109553 CN 99109553 CN 99109553 A CN99109553 A CN 99109553A CN 1279992 A CN1279992 A CN 1279992A
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leaf
medicine
folium
herba
medicated cigarette
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CN1088591C (en
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蔡祺源
蔡迎春
蔡维军
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蔡祺源
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Abstract

A medicine for treating upper respiratory disease is prepared with 19 kinds of Chinese medicinal materials including Flos Chrysanthemi Indici, common perilla, Folium isatidis, Radix zanthoxyli, Herba Schizonepetae, etc. It is prepared into cigarette-like inhalatant, spray preparation and nose drop for use alone or synergetically to treat acute and chronic rhinitis, pharyngitis, trachitis and other upper respiratory diseases.

Description

Medicine of treatment and prevention upper respiratory tract infection and preparation method thereof
The present invention relates to be used for the treatment of and prevent Chinese medicine medicine of upper respiratory tract infection and preparation method thereof.
Upper respiratory tract infection such as acute and chronic rhinitis, pharyngitis, tracheitis are-class commonly encountered diseases, frequently-occurring disease.Itself normal protracted course of disease not only, and can cause multiple complications, harm humans health.Along with the development of industrial society, the air quilt is ground contamination in various degree, makes the sickness rate of upper respiratory tract infection one class diseases such as rhinitis, pharyngitis increase.Effectively prevention and treatment upper respiratory tract infection become an important topic medically.Being used for the treatment of upper respiratory tract infection at present, is the Chinese and western drugs of representative with the antibiotic, perhaps aspect cure rate, perhaps aspect side effect, perhaps aspect degree easy to use, perhaps in expense, in price, exist allly can not make the satisfied part of people.Therefore need seek more effective, medicine and method more easily.The square medicine of excavating prevention and treatment upper respiratory tract infection from Chinese traditional medicine then is a feasible approach.The inventor is according to tcm theory, in conjunction with modern science knowledge, through exploring for many years, test, improving, having finished with the Chinese medicine natural drug is the research creation of main preparation treatment and the pharmaceutical preparation of prevention upper respiratory tract infection, compare exclusive characteristics with existent technique.
The object of the present invention is to provide a kind of Chinese medicine preparation and formulation method, its crude drug is chosen easily, and formulation method is easy, economical, and medicine is easy to use, can treat and prevent upper respiratory tract infection effectively.
The present invention seeks to choose by the following method Chinese medicine, manufacture and burn and suck agent or aerosol, nasal drop is realized.
Medicine is formed: comprise following 19 kinds of components.The wild chrysanthemum leaf willow is pressed leaf Folium Perillae Folium Isatidis shinyleaf pricklyash leaf balm leaf mentha leave Folium Taraxacum houttuynia curdatu leaf Folium Andrographis Herba Violae leaf hedyotis leaf Rhizoma Et Radix Notopterygii Rhizoma Cimicifugae Herba Xanthii Flos Magnoliae Herba Ephedrae Radix Angelicae Dahuricae Radix Saposhnikoviae
Above crude drug generally uses it in product, but also available its bright product.Each survival dose can carry out the combination of different proportion according to factors such as the taste custom of different regions, different sexes, different age people, tolerance degrees in a big way, also can adjust at different disease kind, the more common usage ratio of the state of an illness. is: (dry product percentage by weight) wild chrysanthemum leaf 5-15% willow is pressed the windproof 4-6% of leaf 2-6% perilla leaf 5-10% folium isatidis 5-10% shinyleaf pricklyash leaf 2-5% balm leaf 6-12% dried peppermint leaf 2-6% Folium Taraxacum 2-6% houttuynia curdatu leaf 5-10% Folium Andrographis 2-6% Herba Violae leaf 1-3% hedyotis leaf 1-3% notopterygium root 4-6% rattletop 4-6% Siberian cocklebur 4-6% flower bud of lily magnolia 1-4% Chinese ephedra 1-4% root of Dahurain angelica 15-25%
Use above medicine can make multiple dosage form, preferably the Medicated cigarette type burns and sucks agent, is aerosol and nasal drop secondly.Below narrate their preparation method respectively.
One. make the Medicated cigarette type and burn and suck agent
1. preceding 12 kinds of each medicines with leaf should be that the fresh product of cleaning dry or dry in the above prescription, and not mould not poor, pulverize separately becomes the corase meal of the about 0.2-0.3cm of length (or diameter).
2. Rhizoma Et Radix Notopterygii, Rhizoma Cimicifugae, Herba Xanthii, all medicines of Flos Magnoliae are dried after 4-6 hour or are dried with the wine parch or with the steeping in wine bubble respectively.This several drugs of process processed with wine and Herba Ephedrae, the Radix Angelicae Dahuricae, Radix Saposhnikoviae three medicine pulverize separately are crossed the above dusting cover of 100 orders, get fine powder.
3. get borneol by the weight of prescription drug total amount 1-3%, add and add a little peppermint essence, essence again after 3-5 boiling water doubly dissolves it, shake up borneol liquid.Borneol liquid evenly is sprayed on the drug powder, and all thickness powder mixes are even, adopt the process of making medicated cigarette that drug powder is made the Medicated cigarette type and burn and suck agent.
Two. make aerosol
Burn and suck with making that agent is the same selects medicine, the process of preparing Chinese medicine, pulverizing,, soaked 4-6 hour with clear water with gained thickness drug powder mix homogeneously.Place afterwards to decoct distillation 3-4 time in the sand jar, decocted about 2 hours at every turn, add water after the separation decoction liquor and boil again.Will boil during decoction, container seals, and draws steam and gets distillate simultaneously.Each time decoction liquor is mixed the back with macromolecular material filter paper filtering 2-3 time, remove slag capable again decocting and concentrating medicinal liquid.Medicinal liquid after concentrating is mixed with distillate.
Weight by prescription drug total amount 1-3% is got borneol, adds 3-5 boiling water doubly it is dissolved, shake up " borneol liquid ", join in the above-mentioned medicinal liquid.If too dense being unsuitable for of medicinal liquid sprayed, can add an amount of aquae destillata dilution.The packing aerosol bottle is sealed up for safekeeping after 7 days and is used then.
In the technology of above making aerosol, can save the crude drug pulverizing process, directly crude drug is soaked the back and decoct.
Three. make nasal drop
The processing technology of nasal drop is identical substantially with the making aerosol, just without the aerosol bottle packing, but the finished product medicinal liquid is poured into drop with in the little plastic bottle, is nasal drop.
The invention will be further described by the following examples.
Embodiment 1 produces the Medicated cigarette type and burns and sucks agent
Take by weighing following each medicine dry product: wild chrysanthemum leaf 100g willow is pressed leaf 40g Folium Perillae 70g Folium Isatidis 70g shinyleaf pricklyash leaf 30g balm leaf 80g mentha leave 40g Folium Taraxacum 40g houttuynia curdatu leaf 70g Folium Andrographis 50g Herba Violae leaf 20g hedyotis leaf 20g Rhizoma Et Radix Notopterygii 50g Rhizoma Cimicifugae 50g Herba Xanthii 50g Flos Magnoliae 30g Herba Ephedrae 30g Radix Angelicae Dahuricae 200g Radix Saposhnikoviae 50g
Above medicine total amount is 1090 grams.
Preparation method:
1. wild chrysanthemum leaf, willow are pressed leaf, Folium Perillae, Folium Isatidis, shinyleaf pricklyash leaf, balm leaf, mentha leave, Folium Taraxacum, houttuynia curdatu leaf, Folium Andrographis, Herba Violae leaf, hedyotis leaf etc. and use the leaf medicine for 12 kinds, get it and clean the fresh product person of drying, pulverize separately, cross 50 mesh sieves, it is standby to get the corase meal mix homogeneously.
With Rhizoma Et Radix Notopterygii, Rhizoma Cimicifugae, Herba Xanthii, all medicines of Flos Magnoliae respectively with the wine parch, pulverize oven dry back, crosses 120 mesh sieves, the fine powder mix homogeneously is standby.
3. with Herba Ephedrae, the Radix Angelicae Dahuricae, Radix Saposhnikoviae pulverize separately, cross 120 mesh sieves, it is standby to get the fine powder mix homogeneously.
Above processing step 1,2,3 gained thickness powder mixes are evenly standby 4..
5. get borneol 20g, add 100ml boiling water, add peppermint essence 5g, essence 3g after waiting to dissolve again, shake up and evenly be sprayed in the aerosol apparatus of packing on the drug powder, immediately medicine is sealed 2-3 days with plastic bag or canister.
6. by the process of making medicated cigarette drug powder is made Medicated cigarette, every nearly weighs the 0.4-0.5 gram.Add the rearmounted roasted room baking of outer package 3-4 days, be the finished cigarettes type and burn and suck agent, claim " Folium Nicotianae preparatum spirit ".
By about 18 months of " Folium Nicotianae preparatum spirit " shelf-life of this explained hereafter.
Embodiment 2 produces the Medicated cigarette type and burns and sucks agent (only using 19 kinds of base stock medicines)
Take by weighing following each medicine dry product: wild chrysanthemum leaf 100g willow is pressed leaf 40g Folium Perillae 70g Folium Isatidis 70g shinyleaf pricklyash leaf 30g balm leaf 80g mentha leave 40g Folium Taraxacum 40g houttuynia curdatu leaf 70g Folium Andrographis 50g Herba Violae leaf 20g hedyotis leaf 20g Rhizoma Et Radix Notopterygii 50g Rhizoma Cimicifugae 50g Herba Xanthii 50g Flos Magnoliae 30g Herba Ephedrae 30g Radix Angelicae Dahuricae 200g Radix Saposhnikoviae 50g
Above medicine total amount is 1090 grams.
Preparation method:
1. wild chrysanthemum leaf, willow are pressed leaf, Folium Perillae, Folium Isatidis, shinyleaf pricklyash leaf, balm leaf, mentha leave, Folium Taraxacum, houttuynia curdatu leaf, Folium Andrographis, Herba Violae leaf, hedyotis leaf etc. and use the leaf medicine for 12 kinds, get it and clean the fresh product person of drying, pulverize separately, cross 50 mesh sieves, it is standby to get the corase meal mix homogeneously.
With Rhizoma Et Radix Notopterygii, Rhizoma Cimicifugae, Herba Xanthii, all medicines of Flos Magnoliae respectively with the wine parch, pulverize oven dry back, crosses 120 mesh sieves, the fine powder mix homogeneously is standby.
3. with Herba Ephedrae, the Radix Angelicae Dahuricae, Radix Saposhnikoviae pulverize separately, cross 120 mesh sieves, it is standby to get the fine powder mix homogeneously.
Above processing step 1,2,3 gained thickness powder mixes are even 4., by the process of making medicated cigarette drug powder is made Medicated cigarette, add the rearmounted roasted room baking of outer package 3-4 days, be the finished cigarettes type and burn and suck agent.
Embodiment 3 produces aerosol
Take by weighing following each medicine dry product: wild chrysanthemum leaf 100g willow is pressed leaf 40g Folium Perillae 70g Folium Isatidis 70g shinyleaf pricklyash leaf 30g balm leaf 80g mentha leave 40g Folium Taraxacum 40g houttuynia curdatu leaf 70g Folium Andrographis 50g Herba Violae leaf 20g hedyotis leaf 20g Rhizoma Et Radix Notopterygii 50g Rhizoma Cimicifugae 50g Herba Xanthii 50g Flos Magnoliae 30g Herba Ephedrae 30g Radix Angelicae Dahuricae 200g Radix Saposhnikoviae 50g
Above medicine total amount is 1090 grams.
Preparation method:
Rhizoma Et Radix Notopterygii, Rhizoma Cimicifugae, Herba Xanthii, all medicines of Flos Magnoliae respectively with the wine parch, are mixed with other each medicine in the prescription, soaked 6 hours with clear water.Place afterwards to decoct distillation 3 times in the sand jar, decocted about 2 hours at every turn, add water after the separation decoction liquor and boil again.Remove medicinal residues after decocting 3 times.Container seals during decoction, draws steam and gets distillate simultaneously.Each time decoction liquor is mixed the back with macromolecular material filter paper filtering 2 times, again with the medicinal liquid decocting and concentrating to 1000ml, with medicinal liquid and distillate mixing for standby use.
Get borneol 10g, add 100ml boiling water, treat to shake up after borneol dissolves and make " borneol liquid ".Borneol liquid is joined in the above-mentioned standby medicinal liquid, and the packing aerosol bottle is sealed up for safekeeping after 7 days and is used.
The using method that Medicated cigarette type of the present invention burns and sucks agent is as burning and sucking medicated cigarette, and to suck medicated cigarette hobby person more suitable for have.Smoke 4-6 and prop up general every day.Notice when burning and sucking that the smog suction contains in the mouth, slowly breathe out, do not suck in the lung as far as possible from nasal cavity.When side nasal obstruction is right, available hands is covered strong side, allows smog flow out from sick side nasal cavity as far as possible.After burning and sucking Folium Nicotianae preparatum spirit Medicated cigarette, mouth and nose have cooling feeling and slight hardship, picotement to feel, are the effects that flavour of a drug distribute.
Aerosol and nasal drop are more suitable for using in not sucking medicated cigarette person and child.
Burning and sucking agent, aerosol and three kinds of dosage forms of nasal drop and can using separately of medicine of the present invention also can be united use.
Clinical practice the present invention burns and sucks upper respiratory tract infection patients such as agent and treatment by aerosol 102 routine acute and chronic rhinitis, pharyngitis, tracheitis, smokes 3-4 every day and props up the Medicated cigarette type and burn and suck agent, or use aerosol spray every day to inhale 3-4 time, treats effective percentage and reaches 98%.Most patients took effect after medication 20-30 minute, and subjective symptomss such as nasal obstruction, pharyngalgia, headache alleviate.
Often smoke the present invention when anosis and burn and suck agent or spray suction aerosol of the present invention, drip and use nasal drop, can play the effect of prevention upper respiratory tract infection.Pharmaceutical preparation of the present invention also can be used for treating stomatitis.The people who sucks the medicated cigarette addiction burns and sucks after agent or spray inhale aerosol of the present invention smoking the present invention, and craving for tobacco obviously weakens, so pharmaceutical preparation of the present invention also can be used for giving up (Nicotiana tabacum L. that contains nicotine) craving for tobacco.

Claims (7)

1. medicine that is used for the treatment of and prevents upper respiratory tract infection, it is characterized in that, its component comprises that the wild chrysanthemum leaf willow is pressed leaf Folium Perillae Folium Isatidis shinyleaf pricklyash leaf balm leaf mentha leave dandelion leaf houttuynia curdatu leaf Folium Andrographis Herba Violae leaf hedyotis leaf Rhizoma Et Radix Notopterygii Rhizoma Cimicifugae Herba Xanthii Flos Magnoliae Herba Ephedrae Radix Angelicae Dahuricae Radix Saposhnikoviae
2. medicine according to claim 1, it is characterized in that, its each weight percentages of components is that wild chrysanthemum leaf 5-15% willow is pressed leaf 2-6% Folium Perillae 5-10% Folium Isatidis 5-10% shinyleaf pricklyash leaf 2-5% balm leaf 6-12% mentha leave 2-6% Folium Taraxacum 2-6% houttuynia curdatu leaf 5-10% Folium Andrographis 2-6% Herba Violae leaf 1-3% hedyotis leaf 1-3% Rhizoma Et Radix Notopterygii 4-6% Rhizoma Cimicifugae 4-6% Herba Xanthii 4-6% Flos Magnoliae 1-4% Herba Ephedrae 1-4% Radix Angelicae Dahuricae 15-25% Radix Saposhnikoviae 4-6%
3. medicine according to claim 1 is characterized in that, crude drug is manufactured the Medicated cigarette type burn and suck agent.
4. medicine according to claim 1 is characterized in that, crude drug is manufactured aerosol.
5. medicine according to claim 1 is characterized in that, crude drug is manufactured nasal drop.
6. according to claim 1 and 3 described medicines, it is characterized in that, the process that making Medicated cigarette type burns and sucks agent is, 12 kinds of corase meals that become the about 0.2-0.3cm of length (or diameter) with leaf medicine pulverize separately, all the other each medicated powder are broken into smalls, " the borneol liquid " that sprinkling is prepared with borneol, peppermint essence, essence is made the Medicated cigarette type by the process of making medicated cigarette and is burnt and sucked agent.
7. according to claim 1 and 4 described medicines, it is characterized in that the process of making aerosol is with sealing decoction behind the drug immersion, to get filtrate and distillate mixing packing aerosol bottle.
CN99109553A 1999-07-12 1999-07-12 Medicine for curing and preventing upper respiratory infection and its preparing method Expired - Fee Related CN1088591C (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100377670C (en) * 2004-09-24 2008-04-02 江西本草天工科技有限责任公司 Health-care food contg. Chinese herb medicine and its soft capsule for improving immunity of anti respiratory tract infection, and its prepn.
CN102631583A (en) * 2012-05-07 2012-08-15 王珂 External nasal delivery preparation for preventing and treating influenza
CN104225412A (en) * 2014-09-18 2014-12-24 时新杰 Traditional Chinese medicine for treating upper respiratory infection
CN105560533A (en) * 2014-10-16 2016-05-11 周述谷 Traditional Chinese medicine composition for treating throat disease and preparation method thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100355451C (en) * 2006-01-17 2007-12-19 何天乐 Cold-treating influenza-preventing medicine
CN102526222A (en) * 2012-02-03 2012-07-04 上海现代制药股份有限公司 Traditional Chinese medicine complex prescription for preventing or treating cold and influenza as well as preparation method and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1093590A (en) * 1993-04-16 1994-10-19 毛怡 Brain-clearing spraying medicament for curing common cold
CN1123694A (en) * 1995-09-04 1996-06-05 付耀华 Health-care cigarette made from fig-leaves and its manufacture
CN1199621A (en) * 1996-12-18 1998-11-25 虎发光 Chinese patent drug for rhinitis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100377670C (en) * 2004-09-24 2008-04-02 江西本草天工科技有限责任公司 Health-care food contg. Chinese herb medicine and its soft capsule for improving immunity of anti respiratory tract infection, and its prepn.
CN102631583A (en) * 2012-05-07 2012-08-15 王珂 External nasal delivery preparation for preventing and treating influenza
CN102631583B (en) * 2012-05-07 2014-04-16 王珂 External nasal delivery preparation for preventing and treating influenza
CN104225412A (en) * 2014-09-18 2014-12-24 时新杰 Traditional Chinese medicine for treating upper respiratory infection
CN105560533A (en) * 2014-10-16 2016-05-11 周述谷 Traditional Chinese medicine composition for treating throat disease and preparation method thereof

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