CN1114426C - Powdered 'Yanhouling' medicine and preparing process thereof - Google Patents

Abstract

The present invention relates to traditional Chinese medicine powder, particularly to a powder for treating throat diseases and the preparation method of the powder. The traditional Chinese medicine powder comprises the main components of tinospora sagittata, futokadsura stem and licorice root; the main components are washed cleanly, dried, mixed and ground into powder for sieving, and then, borneol, menthol and auxiliary material are added for uniformly mixing to obtain finished product after the mixed powder is sieved. The traditional Chinese medicine powder has the functions of clearing heat and toxin, removing tumefaction and alleviating pain, and has special curative effects on laryngopharyngitis and tonsillitis; the traditional Chinese medicine powder has the advantages of security, nontoxicity, convenient operation, good application prospect.

Description

A kind of powder for the treatment of laryngopharyngeal diseases and preparation method thereof

The present invention relates to a kind of Chinese powder medicine, particularly a kind of powder that is used for the treatment of laryngopharyngeal diseases and preparation method thereof.

Clinically, laryngopharyngeal diseases is a kind of commonly encountered diseases and frequently-occurring disease, and sickness rate is higher, mainly contains throat hyperemia, swells and ache, symptom such as dysphagia, fever, headache.The medicine of treatment laryngopharyngeal diseases is more on the existing market, has shortcomings such as prescription is unreasonable, curative effect is undesirable.As " SHANGLIAOHOUFENG SAN " that Meizhou, Guangdong Province pharmaceutical factory produces, mainly form by Margarita, Calculus Bovis, Rhizoma Coptidis, borneol, Radix Glycyrrhizae, Radix Sophorae Tonkinensis, spring black pigment used by women in ancient times to paint their eyebrows, laryngopharyngeal diseases there is certain curative effect, curative effect is undesirable, flavour of a drug are bitter, patient is difficult to shortcomings such as adaptation but exist.Chinese patent CN1093914A disclosed a kind of acute throat trouble and loose on October 26th, 1994; mainly by Margarita, Calculus Bovis, borneol, catechu, Borax, white sulfone, Bombyx Batryticatus, Bulbus Fritillariae Cirrhosae, speckled celadon black pigment used by women in ancient times to paint their eyebrows, Cortex Phellodendri, Rhizoma Coptidis, Herba Menthae, Radix Scutellariae, Radix Glycyrrhizae through cleaning, drying; ground and mixed forms one by one; pharyngolaryngitis, tonsillitis there are curative effect preferably, but have prescription complexity, the higher shortcoming of cost.

The purpose of this invention is to provide a kind ofly has the pure Chinese powder medicine of unique curative effect to laryngopharyngeal diseases, and has reasonable recipe, preparation method characteristics simple, with low cost.

The object of the present invention is achieved like this:

Main Ingredients and Appearance of the present invention is: by the mixture that limacia sagittata, FENGSHATENG, Radix Glycyrrhizae are formed, the weight ratio of its each component is 1～4: 3～5: 2～8.

In order to strengthen antiinflammatory, analgesic effect, above-mentioned preparation also contains an amount of borneol, Mentholum and adjuvant.

Through clinical verification, limacia sagittata, FENGSHATENG, Radix Glycyrrhizae three's weight ratio is 1～3: 3～4 in the mixture: 3～6, and borneol, Mentholum and adjuvant, curative effect is preferable.

Through clinical verification, limacia sagittata, FENGSHATENG, Radix Glycyrrhizae three's weight ratio is 2: 3: 4 in the mixture, borneol, Mentholum and adjuvant, curative effect the best.

Preparation method comprises the following steps:

A. get limacia sagittata and clean and to dry, put food steamer steaming 1～2 hour, dry again with wine (in 10: 1 ratios);

B. get FENGSHATENG and clean and to dry, it is wooden to remove root,, dries with rice vinegar (in 10: 1 ratios) stir-fry with pure root bark again;

C. Radix Glycyrrhizae is cleaned, and crosscut fragmentates, and adds strong brine (in 20: 1 ratios) and fries to sallow;

D. above-mentioned three kinds of medicines are mixed in proportion, fine grinding, cross 280 eye mesh screens the taupe powder;

E. in above-mentioned medicamental pulverata, add borneol (oral), Mentholum, right amount of auxiliary materials, after 280 eye mesh screens, make them more than fineness 280 orders behind the mixing, be finished product.

Limacia sagittata: claim Radix Tinosporae, Pseudobulbus Cremastrae Seu Pleiones, Herba Elephantopi scaberis again

Main component: Radix Tinosporae alkali and tinosporine

Pharmacological action: heat-clearing and toxic substances removing, sharp larynx pain relieving

Nature and flavor: bitter, cold

Function: heat-clearing and toxic substances removing, the emaciation due to emotional upset that looses swell

Cure mainly: clear larynx swells and ache, aphtha of the mouth and tongue, external application are swollen bitterly

Clinical practice: control acute pharyngitis, tonsillitis, laryngopharynx swelling and pain with the dysphagia FENGSHATENG: claim main components such as Fructus Schisandrae Sphenantherae, ZIJINTENG again: 6-elemenol and table-6-elemenol, pectin, organic acid, protein etc.Nature and flavor: hot, bitter, temperature function: blood circulation promoting regulates qi, dispelling, collateral-activating, reducing swelling and alleviating pain cure mainly: according to " Fujian traditional herbal medicine " record, FENGSHATENG can be controlled carbuncle, to laryngalgia curative effect the best.Clinical practice: root bark is controlled innominate toxic swelling (Chinese herbal medicine collection of illustrative plates and proved recipe) Radix Glycyrrhizae: claim Radix Glycyrrhizae, Herba Hedyotis cantonensis root main component again: the glycyrrhizin pharmacological action: the detoxifcation antiallergic; Spasmolytic and expelling phlegm for arresting cough; Antiinflammatory; The protection pharyngolaryngeal mucosa; Effect such as adrenocortical hormone borneol (oral): function: causing resuscitation with aromatic drugs, clearing away heat to alleviate pain pharmacological action: stimulating central nervous system system; Antibiotic (staphylococcus aureus, escherichia coli, microsporum lanosum, red hair moss bacterium bacterium etc. are had inhibitory action) clinical practice: heat clearing and inflammation relieving, reducing swelling and alleviating pain, control laryngopharynx swelling and pain, thrush Mentholum evident in efficacy: the effect adjuvant that mainly contains detumescence antiinflammatory, antalgesic-antipruritic, refrigerant throat, blood circulation promoting: solubility is essence or purified starch etc. recklessly.

The mixture that forms after the above-mentioned each component medicament mixed has heat-clearing and toxic substances removing, the detumescence antiinflammatory, and refrigerant sore-throat relieving wets one's whistle, protection pharyngolaryngeal mucosa, elimination mucous hyperemia, edema, analgesic effect.Acute and chronic pharyngitis, tonsillitis, throat abscess, retropharyngeal abscess, larynx cellulitis, stomatitis, glossitis, gingivitis, thrush etc. there is special efficacy.The present invention has following advantage compared to existing technology:

1. this medicine is a powder, can be sprayed directly on to the affected part, particularly throat illness such as acute and chronic pharyngitis, tonsillitis, throat abscess, laryngalgia, stomatitis, glossitis, tooth inflammation is had unique curative effect, and simultaneously, this medicine also can be made into buccal tablet or capsule;

2. owing to gelationus effect in the FENGSHATENG, behind the spray larynx, medicine can adsorb the affected part pharyngolaryngeal mucosa, plays the effect of protection mucosa, and stops the long period.Form concentration medicine, lasting medicine;

3. this medicine reasonable recipe is easy to use, and mouthfeel is good, and is evident in efficacy, short treating period, and recovery from illness in general 2～4 days gets final product pain relieving after the medication, and alleviates symptom such as dysphagia;

4. this medicine is the pure Chinese medicinal preparation safety non-toxic, has no side effect, and manufacture method is simple, and cost is lower.

Embodiment 1 prescription of the present invention is: mix its weight ratio 2: 3: 4, surplus borneol (oral), Mentholum and right amount of auxiliary materials by limacia sagittata, FENGSHATENG, Radix Glycyrrhizae.Preparation method is as follows:

A. get limacia sagittata and clean and to dry, claim dry product 10kg, place in the food steamer, add wine 1kg, steamed 1～2 hour,, dry standby again to there not being vinosity;

B. get FENGSHATENG and clean and to dry, it is wooden to remove root, with its pure root bark, takes by weighing dry product 10kg, adds rice vinegar 1kg, fries to rice vinegar to be sucked by root bark fully, and taking-up is dried standby again;

C. get Radix Glycyrrhizae and clean, crosscut fragmentates, and takes by weighing dry product 10kg, adds strong brine (saturated solution) 0.5kg, fries to sallow standby;

D. get above-mentioned finished limacia sagittata, FENGSHATENG, Radix Glycyrrhizae by 2: 3: 4 mixed, fine grinding is filtered with 280 eye mesh screens;

E. add borneol (oral), Mentholum, and right amount of auxiliary materials such as purified starch again, filter after 280 eye mesh screens behind the mix homogeneously, make its fineness more than 280 orders, i.e. finished product, can divide to install in the plastics spray bottle to become spray, become in also can incapsulating and control the throat capsule.

As finished product medicated powder being added commercially available buccal tablet substrate also can be made into the buccal tablet of treatment laryngopharyngeal diseases.

This medicine is the taupe powder, and sweet in the mouth is sweet, and mouthfeel is good, good effect.

Embodiment 2

Prescription of the present invention is: mixed its weight ratio 4: 5: 2, surplus borneol (oral), Mentholum and right amount of auxiliary materials by limacia sagittata, FENGSHATENG, Radix Glycyrrhizae.

Preparation method is identical with embodiment 1, and the mixture that makes is the taupe powder, heat reliving and toxin-eliminating, and the effect of relieving sore throat and pain is obvious, and the effect of anti-inflammation detumescence is relatively poor, but flavor is bitter partially, and mouthfeel is poor.

Embodiment 3

Prescription of the present invention is: limacia sagittata, FENGSHATENG, Radix Glycyrrhizae, its weight ratio 1: 5: 8, surplus borneol (oral), Mentholum and right amount of auxiliary materials.

Preparation method is identical with embodiment 1, and the mixture that makes is a brown powder, heat reliving and toxin-eliminating, and the effect of anti-inflammation detumescence is obvious, and the effect of relieving sore throat and pain is relatively poor, and it is sweet partially to distinguish the flavor of.

Usage and dosage: be sprayed directly on to the throat affected part, every day 3～5 times.Clinical trial:

I took up a job as a doctor for three more than ten years, treated 800 many cases laryngopharyngeal diseases patients with this medicine, and play refrigerant pain relieving after the medication at once, wet one's whistle, comfortable effect, curative effect is very good.

1. to 420 3～4 treatments routine tonsil patient every day, symptom on the 1st～2 can be alleviated and accounts for 80%, and surplus patient can fully recover in 3～4 days, effective percentage 100%;

2. 300 routine acute pharyngolaryngitis patients are treated, remission on the 1st～2 account for 90%, surplus patient can fully recover on the 3rd～5, effective percentage 100%;

3. 80 routine ulcer type pharyngolaryngitis are treated, 50 examples of 1～2 day produce effects account for 63%, and surplus patient can fully recover in 2～8 days, effective percentage 100%.Control and test:

1. this presses down first Room street, Liu, male, 47 years old, peasant.Generate heat, have a headache, have sore throat, larynx is swollen, dysphagia, after treating, infused, have an injection, take medicine four days in local commune hospital, the state of an illness take a favorable turn, but not obvious.My health station diagnosis and treatment in 13, morning of 73 on JIUYUE are generated heat 39.5 ℃, right side antiadoncus, surface coverage tunica albuginea, throat pain unbearably, dysphagia, sialorrhea, headache, whole body is suffered from pain.Examine and be acute tonsillitis, the traditional Chinese medical science is called single pretty young woman.Because of not gulping down tablet, with the spirit of spray throat, blow larynx repeatedly earlier, blow the back pain relief, can drink water the clothes anti-inflammation that continues, 2 doses in Chinese medicine.Advise and spray larynx repeatedly.Examined in 14 days two, tonsil suppuration diabrosis is suppurated, and symptom subtracts greatly behind the ulceration, can take food, and heat is moved back.Examined in 15 days three, General Symptoms disappears, and advises and sprays larynx again, clothes antibiotic medicine, recovery from illness.

2. this town descends Ke Tang village, chapter, man, 39 years old.Had sore throat 3 days, once obeyed Chinese herbal medicine, Western medicine, antibiotic medicine.Afternoon on February 7th, 93, come my health station diagnosis and treatment through looking into, throat hyperemia, edema, as the red cloth shape, giddy has larynx to hate, no expectorant, hoarseness, larynx is felt burn feeling, desire for cold drinks, but more feel pain after drinking.Examine and be acute pharyngolaryngitis, blow larynx, building, Kingsoft capsule (plan side certainly) with the spirit of spray throat.Further consultation on the 8th, pharyngitis is congested obviously to be reduced, and sound is clear, and no longer desire for cold drinks is had sore throat, and swallows easily.Advise the spirit of spray throat again, clothes building, Kingsoft capsule.Examined in 9 days three, above symptom obviously disappears, and continues and advises the spirit of spray throat, clothes building, Kingsoft capsule, recovery from illness.

3. Zheng, man, 28 years old, the cadre of people's commune generates heat 38.5 ℃ headache, dysphagia, throat tonsil are seen big or small irregular lamellar ulcer surface, surface coverage yellow-white purulence film, halitosis was come my health station diagnosis and treatment on the 20th in 74 years JIUYUE, examined to be acute pharyngolaryngitis (ulcer type), the traditional Chinese medical science is examined and is false membrane in throat disease, the larynx cellulitis is blown larynx with the spirit of spray larynx, three doses of clothes Mulberry Pueraria lobota soup.Examined in 22 days two, heat is not moved back head not bitterly, swallows improvement, and the HUANGBAI(sic) film reduces, and is mouthful smelly, but feel that larynx does.Advise and continue the spirit of spray throat, take Sang Ge Tonga replenishing body fluid and clearing away heat pathogen medicine again.Examined in 25 days three, symptom greatly takes a turn for the better, and tunica albuginea moves back to the greatest extent, leaves a few cloudlet lamellar flesh noodles and advises and spray the larynx spirit again, and every day for several times.Examined in 26th, recovery from illness restores to the original state, and advises and sprays throat again, consolidates curative effect.

4. village, Lee, women, 32 years old, certain employee are closed in this Zhenan County.Giddy, headache is had sore throat, and swallows obstruction, and the following enlargement of the facial ear in right side 5 days once took traditional Chinese medicine, medical herbs, Western medicine, did not feel any better.Come the health station diagnosis and treatment on February 27th, 75.Look into, generate heat 40 ℃, headache, giddy, the following enlargement of the facial ear in right side is had sore throat.Pharyngeal inspection: the both sides tonsil has moderate swelling, and the right side tonsil is other the big lump of Semen Litchi, pharyngeal hyperemia, and swelling has the pus point, and uvula is pushed to offside, touch soft and fluctuation is arranged, lump suppurates.Dysphagia, limitation of mouth opening, mouthful saliva outflow, glossolalia.Examine and be acute suppuration peritonsillar abscess.Belong to moderate laryngalgia, larynx pass pain.Earlier with the spirit of spray larynx, day several.The color sirloin of the moistening and cleaning throat that takes traditional Chinese medicine Tonga subtracts two doses.Further consultation on the 28th behind the spray larynx, is felt all right, and middle afternoon nap larynx has thing infraction, promptly coughs it, coughs back vomiting pus bloody sputum, and a feel throat has been got well a greater part of.29, whole body condition of illness takes a turn for the better, and was comfortable, but the blood streak is arranged when coughing.Advise and spray the throat spirit again, take traditional Chinese medicine, accuse more.

Claims (5)

1. a powder for the treatment of laryngopharyngeal diseases is characterized in that Main Ingredients and Appearance is: limacia sagittata, FENGSHATENG, Radix Glycyrrhizae, the weight ratio 1～4: 3～5: 2～8 of each component.

2. by the described powder of claim 1, it is characterized in that it also contains borneol, Mentholum and adjuvant.

3. by claim 1 or 2 described powders, the weight ratio that it is characterized in that limacia sagittata, FENGSHATENG, Radix Glycyrrhizae three is 1～3: 3～4: 3～6.

4. by claim 1 or 2 described powders, the weight ratio that it is characterized in that limacia sagittata, FENGSHATENG, Radix Glycyrrhizae three is 2: 3: 4.

5. the manufacture method of a powder as claimed in claim 1 or 2 is characterized in that comprising the following steps:

A. get limacia sagittata and clean and to dry, to put food steamer with wine and steamed 1～2 hour, dry again;

B. get FENGSHATENG and clean and to dry, it is wooden to remove root,, dries with the rice vinegar stir-fry with pure root bark again;

C. Radix Glycyrrhizae is cleaned, and crosscut fragmentates, and adds strong brine and fries to sallow;

D. above-mentioned three kinds of medicines are mixed in proportion, fine grinding, cross 280 eye mesh screens the taupe powder;

E. add borneol, Mentholum and adjuvant in the powder, mixing makes them more than fineness 280 orders after 280 eye mesh screens, is finished product.