CN1279967C - Medicine of regional external application for treating petvic inflammatory disease of women and preparing method - Google Patents
Medicine of regional external application for treating petvic inflammatory disease of women and preparing method Download PDFInfo
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- CN1279967C CN1279967C CN 200410092445 CN200410092445A CN1279967C CN 1279967 C CN1279967 C CN 1279967C CN 200410092445 CN200410092445 CN 200410092445 CN 200410092445 A CN200410092445 A CN 200410092445A CN 1279967 C CN1279967 C CN 1279967C
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Abstract
The present invention discloses a local externally applied medicine for treating pelvic inflammation of gynecology. The present invention is characterized in that a conventional paste substrate and substances comprising mongolian dandelion herb, sand caraway seed, mirabilite, bupleurum root, Sichuan rhizoma, mint, pollen, frankincense, myrrh, ginger worm, turmeric, red peony root, baical skullcap root, phellodendron bark, borneol and dahurian angelica root are used as raw material; after the substances are respectively pulverized and concentrated into extracts, the extracts and the paste substrate are mixed and applied; after coated with an ointment adhesive, the ointment is cut into square ointments, and thus, paste ointments are formed. The present invention belongs to a purely natural plant Chinese herbal medicine preparation and has favorable effect on acute and chronic hepatitis pelvic inflammation, adnexitis, enclosed masses, etc. The local externally applied medicine directly acts on local parts, and active ingredients of the medicines are directly induced to diseased parts through skin permeation, acupuncture point stimulation and meridian conduction so as to regress the inflammation of the pelvic cavity and the lower abdomen and improve subjective symptoms of patients; besides, the local externally applied medicine can promote the resolution, absorption and cure of inflammation.
Description
Technical field
The present invention relates to a kind of local external application medicine for the treatment of gynecologic pelvic inflammatory disease, the invention still further relates to the preparation method of these application compress.
Background technology
At present gynaecopathia is the most obscure in the world disease, does not limit the age, so long as the woman all have gynopathic probability, show that according to " about the report of China's WomanHealth situation " statistics 87.59% women suffers from gynaecopathia in various degree.Wherein pelvic inflammatory disease, adnexitis account for gynecological's morbidity 65%, are one of higher disease kinds of gynaecopathia sickness rate.For curing this disease, by its conventional therapy with oral medicine, have an injection, therapies such as operation, coloclysis, though effectively alleviate disease, repeatedly recurrence is easily returned and is answered obstinate.This disease is long-time touching not to heal, and grievous injury women physical and mental health, the women who has due to illness disease seriously and have forever lost work or fertility.40% women does not know oneself to catch an illness, and 50% women is because of being too shy to speak out or psychological causes is refused to say anything about the disease of oneself, and when finding disease and leukorrhagia, gynaecopathia is hidden for a long time on one's body at you, and has shown effect.At this moment, the women just carries on the back heavy psychological burden of cloth-wrapper and psychology slight illness.
Summary of the invention
The purpose of this invention is to provide a kind of local external application medicine for the treatment of pelvic inflammation, stick mode, reach therapeutic effect, have safety, no pain, characteristics easy to use by employing.
Another object of the present invention provides the preparation method of the local external application medicine of this treatment gynecologic pelvic inflammatory disease.
Solution of the present invention is based on body surface and internal organs have special relation, thereby inner disease outer treat is one of Chinese traditional treatment.The reason of external treatment, i.e. the reason of treatment by oral administration of medicines, the medicine of external treatment that is the medicine of treatment by oral administration of medicines, the sticking of different Zhe Faer, part, affected part, acupuncture point, can play the promoting flow of QI and blood of whole body, heat-clearing and toxic substances removing, the effect of dredge the meridian passage, removing the heresy that gets rid of illness, pain relieving eliminating stagnation and reach and cure sick effect.
Application compress of the present invention are to select conventional plaster stroma for use and contain (consumption is a weight portion) that the following weight proportion raw material is made:
Herba Taraxaci 10-20 Folium et Cacumen Artemisiae Halodendri seed 15-20 Radix Trichosanthis 20-50 Radix Et Rhizoma Rhei 30-45
Rhizoma Curcumae Longae 25-45 Bombyx Batryticatus 15-20 Cortex Phellodendri 15-35 Radix Scutellariae 35-40
Radix Bupleuri 10-20 Olibanum 5-15 Myrrha 5-15 Borneolum Syntheticum 5-15
Radix Paeoniae Rubra 15-20 Natrii Sulfas 20-50 Herba Menthae 10-15 Radix Angelicae Dahuricae 10-20
The weight proportion of application compress raw material of the present invention is:
Herba Taraxaci 20 Folium et Cacumen Artemisiae Halodendri seeds 20 Radix Trichosanthis 30 Radix Et Rhizoma Rhei 30
Rhizoma Curcumae Longae 30 Bombyx Batryticatus 20 Cortex Phellodendris 20 Radix Scutellariaes 35
Radix Bupleuri 10 Olibanums 15 Myrrhas 15 Borneolum Syntheticums 15
Radix Paeoniae Rubra 20 Natrii Sulfas 40 Herba Menthaes 15 Radixs Angelicae Dahuricae 15
The preparation method that above-mentioned each raw material is made application compress of the present invention is:
1, at first gets above-mentioned raw material except that Olibanum, Myrrha, Borneolum Syntheticum, soaked 2-4 hour, decoct with water again 2 times, medicinal liquid merges, after being concentrated into 1: 1 concentration, 95% the ethanol that adds 2 times stirs evenly, and room temperature left standstill 48 hours, filter waste, decompression recycling ethanol, the extractum that is concentrated into proportion 1.23-1.28 is standby;
2, it is standby Olibanum, Myrrha, Borneolum Syntheticum powder to be broken into 120 order fine powders;
3, above-mentioned whole extractum and fine powder are mixed after, add and promptly obtain unguentum after medicinal transdermal agent and plaster stroma stir evenly, promptly make the plaster finished product with cutting behind the dressing system cream.
Above-mentioned plaster stroma is to select medical pressure-sensitive adhesive or cataplasma for use.
This method also comprises above-mentioned raw material is added water 1500-2500 milliliter, endure before the heating to 800-1000 milliliter waste, continue decocting on the slow fire to the 550-600 milliliter, be condensed into cream and add 50 milliliters of 2% azones, add the plaster stroma mixing, be finished product with the cutting of dressing system cream.
Treatment mechanism of the present invention is owing to each layer tissue of human body skin surface especially horny layer surface, and very strong semipermeability is arranged, and it is a kind of approach that medicine enters human body that skin has a large amount of pores and sweat duct.Stomach wall is softer, and surface horny is thin tender, and medicine is easy to penetrate and is absorbed.This plaster performance has very strong anti-inflammation detumescence and analgesic effect.
Because pelvic inflammatory disease, adnexitis belong to gathering of Chinese medicine, leukorrhagia lump in the abdomen, dampness and heat stasis or cold-damp stasis of blood knot.It is unclean because of sexual life, does not notice that multiparity takes good care of oneself, and the Personal hygiene custom is bad, makes and invades in the evil poison or the diseases caused by exogenous pathogenic factor cold and heat, and pathogenic heat is lingered on to dash and appointed, and involves uterus and causes.
(1) lower abdomen dull pain and lumbosacral region acid distending pain occurs, sexual intercourse and menstruation or work back pain increase the weight of.
(2) menoxenia, leucorrhea is many.
(3) secondary infertility.
(4) hypogastric region one side pressure pain or both sides pain and distending pain.
(5) bilanual gynecological examination, the adnexa place can touch the lump that differs in size, or hard by it, and what push away is mobile or soft movable, and the capsule sexuality is arranged, with menoxenia, profuse leukorrhea, the clinical adnexitis part enclosed mass that is called.The then easy promoting flow of QI and blood of the effect of Dressed plaster local patholoic change, heat clearing away uncharms, dredge the meridian passage, eliminating stasis to stop pain, thus make patient's rehabilitation.
Plaster of the present invention has following advantage:
1, the herbal raw material selected for use of the present invention, each component meets the pharmaceutical control and administration rules, by partial application therapy, reaches therapeutic purposes, and human body is had no side effect, and is easy to use, economic security.Modest viscosity, permeance property is good, does not pollute skin is non-stimulated, takes off subsides repeatedly and still keeps rendeing a service.
2, plaster of the present invention has the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, circulation of qi promoting intestinal stasis relieving, and treatment pelvic inflammatory disease, adnexitis are had original curative effect.And be suitable for the use, safe and reliable, easy to use of the female patient of various all ages and classes.
For showing that application compress of the present invention are to pelvic inflammatory disease, the therapeutic effect of adnexitis, this pelvic inflammatory disease, the adnexitis patch spreads on the part and can closely contact with skin, be difficult for sliding, form air-tight state at affected area skin, sweat is difficult to evaporation, diffusion, about making Keratoderma layer water content by 5%-15%, increase to 50%, after cuticular layer feedwater cooperation is used, be expandable into porous state, be easy to medicine and penetrate, make the skin permeation rate of medicine can increase 4-5 doubly, simultaneously because skin temperature increases to 37 degree from 30 degree, promote the Transdermal absorption of medicine, directly entered blood circulation, changed pelvic inflammatory disease, central nervous system's function of adnexitis patient, thereby improve the absorption of disappearing that local pathological change promotes inflammation, reach the purpose of healing.
Using method and consumption: this plaster directly is affixed on the patient, changes once in per two days, and it is a course of treatment that logotype 6-16 pastes.
Through 80 routine patients have been done curative effect statistical observation, with local topical gynecological antiinflammatory patch, matched group compares with the Chinese and western medicine conservative treatment treatment group merely, and the result is as follows:
Table 1 compares for curative effect:
| Group number | The example number | Cure rate | Effective percentage | Change other therapies after invalid |
| The treatment group | 80 | 70 examples account for 87.8% | 8 examples account for 97.5% | 2 examples account for 2.5% |
| Matched group | 40 | 30 examples account for 75% | 7 examples account for 92.5% | 3 examples account for 7.5% |
Table 2 compares for healing time:
| Group number | The example number | Acute pelvic inflammatory disease, adnexitis | Chronic pelvic inflammatory disease, adnexitis | Healing time | Recurrence |
| The treatment group | 80 | 6 examples account for % | 74 examples account for % | 6-30 | 2 examples account for 2.5% |
| Matched group | 40 | 10 examples account for % | 30 examples account for % | 1-3 month | 3 examples account for 7.5% |
Observe in detail proof by 80 examples, this plaster is compared with other therapies, has substantial characteristics and significant curative effect, and tool novelty, practicality and engrossment of market have the bright prospects of very strong vitality in medical domain, biology.
The exterior patch treatment, patient's abdomen is painful, tired, soreness of waist pain, leukorrhagia all has clear improvement, and treats acute adnexitis 6 examples, cures 5 examples a course of treatment, cure 1 example two courses of treatment, chronic adnexitis 74 examples, cure 64 examples a course of treatment, and 8 examples take a turn for the better, invalid 2 examples, total effective rate 97.5%, cure rate 87.5%, invalid 2.5%.
This sticks local skin and does not see any allergy and other untoward reaction.Gynecological's Anti-inflammatory plaster is that natural wild plant is refined the analgesic ointment cream that forms, and is safe and simple to department of obstetrics and gynecology inflammation curative effect height, economical without any side effects.More evident in efficacy than conventional anti-inflammatory analgetic oral medicine and enema therapy etc., have and cure the high advantage that does not rebound.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Choose raw material (kilogram) by following proportioning:
Herba Taraxaci 2 Folium et Cacumen Artemisiae Halodendri seeds 2 Radix Trichosanthis 3 Radix Et Rhizoma Rhei 3
Rhizoma Curcumae Longae 3 Bombyx Batryticatus 2 Cortex Phellodendris 2 Radix Scutellariaes 3.5
Radix Bupleuri 1 Olibanum 1.5 Myrrhas 1.5 Borneolum Syntheticums 1.5
Radix Paeoniae Rubra 2 Natrii Sulfas 4 Herba Menthaes 1.5 Radixs Angelicae Dahuricae 1.5
Its preparation methods steps is as follows:
(1) at first getting above-mentioned raw material except that Olibanum, Myrrha, Borneolum Syntheticum soaked 2-4 hour, decoct with water again 2 times, medicinal liquid merge be concentrated into 1: 1 concentration after, 95% the ethanol that adds 2 times stirs evenly, room temperature left standstill 48 hours, filter waste, decompression recycling ethanol, the extractum that is concentrated into proportion 1.23-1.28 is standby;
(2), it is standby Olibanum, Myrrha, Borneolum Syntheticum powder to be broken into 120 order fine powders;
(3), above-mentioned whole extractum and fine powder added promptly obtain unguentum after medicinal transdermal agent and cataplasma plaster stroma stir evenly, be the finished product plaster with cutting behind the dressing system cream.
Above-mentioned plaster stroma also can be selected medical pressure-sensitive adhesive for use.Described cataplasma and medical pressure-sensitive adhesive are buied by market.
Embodiment 2
The raw material of choosing by embodiment 1 proportioning, this method also comprises above-mentioned raw material is added water 1500-2500 milliliter, endure before the heating to 800-1000 milliliter waste, continuation is decocting on the slow fire to the 550-600 milliliter, be condensed into cream and add 50 milliliters of 2% azones, add the plaster stroma mixing, be finished product with the cutting of dressing system cream.
Claims (5)
1, a kind of local external application medicine for the treatment of gynecologic pelvic inflammatory disease is characterized in that it is made up of effective ingredient and conventional plaster stroma, wherein makes raw materials of effective components and consists of:
Herba Taraxaci 10-20 part Folium et Cacumen Artemisiae Halodendri seed 15-20 part Radix Trichosanthis 20-50 part
Radix Et Rhizoma Rhei 30-45 part Rhizoma Curcumae Longae 25-45 part Bombyx Batryticatus 15-20 part Cortex Phellodendri 15-35 part
Radix Scutellariae 35-40 part Radix Bupleuri 10-20 part Olibanum 5-15 part Myrrha 5-15 part
Borneolum Syntheticum 5-15 part Radix Paeoniae Rubra 15-20 part Natrii Sulfas 20-50 part
Herba Menthae 10-15 part Radix Angelicae Dahuricae 10-20 part.
2, by the local external application medicine of the described treatment pelvic inflammation of claim 1, wherein the weight proportion of each raw material is:
30 parts of 30 parts of Radix Et Rhizoma Rhei of 20 parts of Radix Trichosanthis of 20 parts of Folium et Cacumen Artemisiae Halodendri seeds of Herba Taraxaci
35 parts of 20 parts of Radix Scutellariaes of 20 portions of Cortex Phellodendris of 30 parts of Bombyx Batryticatus of Rhizoma Curcumae Longae
15 parts of 15 parts of Borneolum Syntheticums of 15 parts of Myrrhas of 10 parts of Olibanums of Radix Bupleuri
15 parts of 15 parts of Radixs Angelicae Dahuricae of 40 portions of Herba Menthaes of 20 parts of Natrii Sulfas of Radix Paeoniae Rubra.
3, by the local external application medicine of claim 1 or 2 described treatment pelvic inflammations, it is characterized in that described medicament is the external application putty-type.
4, a kind of preparation method that is used for the local external application medicine of claim 3 treatment gynecologic pelvic inflammatory disease, the steps include: that (1) at first get above-mentioned raw material except that Olibanum, Myrrha, Borneolum Syntheticum and soaked 2-4 hour, decoct with water again 2 times, medicinal liquid merge be concentrated into 1: 1 concentration after, 95% the ethanol that adds 2 times stirs evenly, room temperature left standstill 48 hours, filtered waste, decompression recycling ethanol, and the extractum that is concentrated into proportion 1.23-1.28 is standby;
(2) it is standby Olibanum, Myrrha, Borneolum Syntheticum powder to be broken into 120 order fine powders;
(3), above-mentioned whole extractum and fine powder added obtain unguentum after medicinal transdermal agent and plaster stroma stir evenly, be the finished product plaster with cutting behind the dressing system cream.
5, by the described preparation method of claim 4, this method also comprises above-mentioned raw material is added water 1500-2500 milliliter, endure before the heating to 800-1000 milliliter waste, continuation is decocting on the slow fire to the 550-560 milliliter, be condensed into cream and add 50 milliliters of 2% azones, add the plaster stroma mixing, be finished product with the cutting of dressing system cream.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410092445 CN1279967C (en) | 2004-12-23 | 2004-12-23 | Medicine of regional external application for treating petvic inflammatory disease of women and preparing method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410092445 CN1279967C (en) | 2004-12-23 | 2004-12-23 | Medicine of regional external application for treating petvic inflammatory disease of women and preparing method |
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| Publication Number | Publication Date |
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| CN1660293A CN1660293A (en) | 2005-08-31 |
| CN1279967C true CN1279967C (en) | 2006-10-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200410092445 Expired - Fee Related CN1279967C (en) | 2004-12-23 | 2004-12-23 | Medicine of regional external application for treating petvic inflammatory disease of women and preparing method |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579982A (en) * | 2012-03-05 | 2012-07-18 | 杨彦君 | Externally-applied patch of for local point to treat gynecologic pelvic inflammatory disease and preparation method thereof |
| CN104306505A (en) * | 2013-12-05 | 2015-01-28 | 戴东云 | Powder for drawing out toxin |
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Granted publication date: 20061018 Termination date: 20101223 |