CN102579982A - Externally-applied patch of for local point to treat gynecologic pelvic inflammatory disease and preparation method thereof - Google Patents

Externally-applied patch of for local point to treat gynecologic pelvic inflammatory disease and preparation method thereof Download PDF

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Publication number
CN102579982A
CN102579982A CN2012100546492A CN201210054649A CN102579982A CN 102579982 A CN102579982 A CN 102579982A CN 2012100546492 A CN2012100546492 A CN 2012100546492A CN 201210054649 A CN201210054649 A CN 201210054649A CN 102579982 A CN102579982 A CN 102579982A
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parts
powder
radix
far infrared
infrared ceramic
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杨彦君
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Abstract

The invention discloses an externally-applied patch of for local points to treat gynecologic pelvic inflammatory diseases. A conventional plaster matrix and traditional Chinese herbs are used as raw materials, the applied traditional Chinese herbs include dandelion, artemis sphaerocephala krasch, radices trichosanthis, rheum officinale, turmeric, bombyx batryticatus, cortex phellodendri, radix scutellariae, radix bupleuri, olibanum, myrrh, borneol, radix paeoniae rubra, mirabilite, mentha haplocalyx, radix angelicae and oldenlandia diffusa. The raw materials are crushed, concentrated and extracted to prepare extract, far infrared ceramic powder, magnetic powder and nano silver powder are added and mixed with the plaster matrix in a coating way, and thus cream paste is prepared. Since the patch is prepared with natural traditional Chinese herbs, far infrared ceramic powder, magnetic powder and nano silver powder, the patch has good effects of activating main and collateral channels, promoting blood circulation, removing stasis, eliminating inflammation, swelling and pains, and treating gynecological acute and chronic pelvic inflammatory diseases, masses, dysmenorrheal and cervical erosion. Due to the mechanical stimulation of points and direct leading of the pharmaceutical ingredients into focuses by the far infrared ceramic powder, the magnetic powder and the nano silver powder through the main and collateral channels, the inflammation dissipation and absorption can be promoted to achieve curing effects. The plaster also has good effects on treatment of cervical spondylosis, lumbar spine and other surgical inflammation.

Description

Local acupuncture points external application patch of treatment gynecologic pelvic inflammatory disease and method for preparing
Technical field
The present invention relates to local acupuncture points external application patch of a kind of treatment gynecologic pelvic inflammatory disease and method for preparing, be used to treat gynaecopathia, and all effective in cure to cervical spondylosis, lumbal vertebra and other surgery inflammation.
Background technology
Gynaecopathia is the most obscure in the world disease, does not limit the age, so long as the woman all have gynopathic probability.Show that according to " about the report of China's WomanHealth situation " statistics 87.59% women suffers from gynaecopathia in various degree.Wherein pelvic inflammatory disease, cervical erosion account for gynecological's morbidity 65%, are one of higher disease kinds of gynaecopathia sickness rate.For curing this disease, by its conventional therapy with oral medicine, have an injection, therapies such as operation, coloclysis.Though effectively alleviate disease, repeatedly recurrence easily, obstinate.Grievous injury the women physically and mentally healthy, the women who has due to illness disease seriously and has forever lost work or fertility.Have 40% women not know oneself to catch an illness according to investigations, 50% women is because of being too shy to speak out or psychological causes is refused to say anything about its disease, and when finding this disease and leukorrhagia, health has been suffered from gynaecopathia in various degree, and has hidden for a long time.The outbreak of this disease can make the women carry on the back heavy psychological burden of cloth-wrapper and psychology slight illness.
Summary of the invention
The purpose of this invention is to provide the local acupuncture points external application patch of a kind of treatment pelvic inflammation, stick mode, reach therapeutic effect, have safety, no pain, characteristics easy to use through employing.
Another object of the present invention provides the method for preparing of the local acupuncture points external application patch of this treatment gynecologic pelvic inflammatory disease.
Solution of the present invention is based on body surface and internal organs have special relation, thereby inner disease outer treat is one of Chinese traditional treatment.The reason of external treatment, i.e. the reason of treatment by oral administration of medicines, the medicine of external treatment that is the medicine of treatment by oral administration of medicines, the sticking of local, the acupuncture point of different Zhe Faer, affected part, can play the promoting flow of QI and blood of whole body, heat-clearing and toxic substances removing, the effect of dredge the meridian passage, removing the heresy that gets rid of illness, pain relieving eliminating stagnation and reach and cure sick effect.
Acupuncture points external application patch of the present invention is to select conventional plaster stroma for use and contain (consumption is a weight portion) that the following weight proportion raw material is processed:
Herba Taraxaci 10-20, Folium et Cacumen Artemisiae Halodendri seed 15-20, Radix Trichosanthis 20-50, Radix Et Rhizoma Rhei 30-45
Rhizoma Curcumae Longae 25-45, Bombyx Batryticatus 15-20, Cortex Phellodendri 15-35, Radix Scutellariae 35-40,
Radix Bupleuri 10-20, Olibanum 5-15, Myrrha 5-15, Borneolum Syntheticum 5-15,
Radix Paeoniae Rubra 15-20, Natrii Sulfas 20-50, Herba Menthae 10-15, Radix Angelicae Dahuricae 10-20,
Herba Hedyotidis Diffusae 10-20, far infrared ceramic powder 0.5-2, magnetic powder 0.5-2, nanometer silver powder 0.5-2.
The weight proportion of external plaster application agent raw material of the present invention is:
Herba Taraxaci 20, Folium et Cacumen Artemisiae Halodendri seed 20, Radix Trichosanthis 30, Radix Et Rhizoma Rhei 30,
Rhizoma Curcumae Longae 30, Bombyx Batryticatus 20, Cortex Phellodendri 20, Radix Scutellariae 35,
Radix Bupleuri 10, Olibanum 15, Myrrha 15, Borneolum Syntheticum 15,
Radix Paeoniae Rubra 20, Natrii Sulfas 40, Herba Menthae 15, the Radix Angelicae Dahuricae 15,
Herba Hedyotidis Diffusae 10, far infrared ceramic powder 1, magnetic powder 1, nanometer silver powder 1.
The method for preparing that above-mentioned each raw material is processed acupuncture points external application patch of the present invention is:
1, at first gets above-mentioned Olibanum, Myrrha, Borneolum Syntheticum, far infrared ceramic powder, magnetic powder, the raw material outside the nanometer silver powder of removing; Soaked 2-4 hour, decocte with water is 2 times again, combining medicine; After being concentrated into 1:1 concentration, 95% the ethanol that adds 2 times stirs, and room temperature left standstill 48 hours; Filter waste, decompression recycling ethanol, the extractum that is concentrated into proportion 1.23-1.28 is subsequent use;
2, get Olibanum, Myrrha, that Borneolum Syntheticum powder is broken into 130 order fine powders is subsequent use;
3, add Olibanum, Myrrha, Borneolum Syntheticum fine powder, far infrared ceramic powder, magnetic powder, nanometer silver powder in the extractum with step 1 and mix after, add and promptly obtain unguentum after medicinal transdermal agent and plaster stroma stir, promptly make the plaster finished product with cutting behind the dressing system cream.
The plaster stroma of indication is to select medical pressure-sensitive adhesive for use in above-mentioned, or cataplasma.
In the method, also can above-mentioned raw materials be added water 1500-2500 milliliter, endure before the heating to 800-1000 milliliter waste; Continuation is decocting on the slow fire to the 550-600 milliliter; Be condensed into cream and add the Chinese medicine transdermal agent, add the plaster stroma mixing, be finished product with cutting behind the dressing system cream.
The far infrared ceramic powder of indication of the present invention is to be made by inorganic mineral, nonmetal oxide and metallic oxide.This powder can concentrate emission length to be the far infrared of 8-15um; Its normal spectral emissivity is more than 80%, the absorption that human body can be good, and far infrared has good transdermal effect; It can transdermal infiltration 1-5mm, far infrared has preferably that heat effect can cause a series of physiological effect:
1, balance the body's pH; 2, purify the blood and improve skin quality; 3, in different parts of the body to promote blood circulation and the body's microcirculation; 4, enhance immunity and the body's ability Pao thin the blood; 5, activation of Creatures molecular activity, activation of fine Pao; 6, metabolic waste can be rapidly excreted; 7, with inflammation, swelling, analgesic effect; 8, dredge the meridians, promoting blood circulation and analgesic effects.
The magnetic powder of indication of the present invention has blood circulation is strengthened, and neuro humor plays good regulating action, is accompanied by enzymatic activity and strengthens to play jointly and enhance metabolism, and makes vitality more vigorous.Also to the adjustment effect that interacts of human acupoint and bio electricity, the operation of gas is called electromagnetic transmission in the meridians.Also can reduce the irritability of teleneuron and the transmission of the pain sensation, expansible blood vessel, blood circulation promoting quickens the dissipation of inflammatory exudation.
The nanometer silver powder of indication of the present invention has more bigger serface, antibacterial ability is strong, and common anti-Hypomycin can only kill 6-7 kind pathogen, and nanometer silver can kill 650 kinds of microorganisms, and does not have drug resistance.Nanometer silver antimicrobial is general wide, can not produce drug resistance, not limited by antibacterial, and is as safe as a house.
Treatment mechanism of the present invention is: owing to each layer tissue of human body skin surface especially horny layer surface, very strong semipermeability is arranged, it is a kind of approach that medicine gets into human body that skin has a large amount of pores and sweat duct.Stomach wall is softer, and surface horny is thin tender, and medicine is easy to penetrate and is absorbed.This plaster performance has very strong anti-inflammation detumescence and analgesic effect.In addition; Owing to added far infrared ceramic powder, magnetic powder, nanometer silver powder; Have high strength transdermal and strong disinfecting antiinflammation, make common patch stick 6-12 hour of powerful time of the human acupoint promptly visible effect that is reduced to 2 hours, and curative effect increases substantially.
In addition, owing to pelvic inflammatory disease, adnexitis belong to gathering of Chinese medicine, leukorrhagia lump in the abdomen, dampness and heat stasis or cold-damp stasis of blood knot.It is unclean because of sexual life, do not note taking good care of oneself in menstrual period or term, and Personal hygiene custom is bad, causes invading in the evil poison or the diseases caused by exogenous pathogenic factor cold and heat, and pathogenic heat is lingered on to dash and appointed, and involves uterus and causes.As: 1, lower abdomen dull pain and lumbosacral region acid distending pain occurs, sexual intercourse and menstruation or work back pain increase the weight of; 2, menoxenia, leucorrhea is many; 3, secondary infertility; 4, hypogastric region one side pressure pain or both sides pain and distending pain; 5, bilanual gynecological examination, the adnexa place can touch the lump that differs in size, or hard by it, and what push away is mobile or soft movable, has capsule sexy, with menoxenia, profuse leukorrhea, the clinical adnexitis part enclosed mass that is called.
In addition, the effect of applying the plaster local patholoic change then is prone to promoting flow of QI and blood, and heat clearing away uncharms, dredge the meridian passage, eliminating stasis to stop pain, thus make patient's rehabilitation.
Acupuncture points external application patch of the present invention has following advantage:
1, the herbal raw material selected for use of the present invention, each component meets the pharmaceutical control and administration rules, through partial application therapy, reaches therapeutic purposes, and is easy to use to the human non-toxic side effect, economic security.Modest viscosity, permeance property is good, does not pollute skin is non-stimulated, takes off subsides repeatedly and still keeps rendeing a service.
2, acupuncture points external application patch has the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, circulation of qi promoting intestinal stasis relieving, and treatment pelvic inflammatory disease, adnexitis, cervical erosion are had original curative effect.And the female patient that is suitable for various all ages and classes use, safe and reliable and easy to use.
For showing the therapeutic effect of acupuncture points external application patch of the present invention to pelvic inflammatory disease, adnexitis, this pelvic inflammatory disease, adnexitis patch spread on local acupuncture point and can closely contact with skin, are difficult for sliding; Form air-tight state at affected area skin, sweat is difficult to evaporation, diffusion, make Keratoderma layer water content by 5%-15% about; Increase to 50%, after cuticular layer feedwater cooperation is used, be expandable into porous state; Be easy to medicine and penetrate, make the skin permeation rate of medicine can increase 4-5 doubly, simultaneously because skin temperature increases to 37 degree from 30 degree; The heat effect function that in addition is aided with far infrared ceramic powder, magnetic powder, nanometer silver powder has promoted the Transdermal absorption of medicine directly to get into blood circulation; Change central nervous system's function of pelvic inflammatory disease, adnexitis patient, thereby improve the absorption of disappearing that local pathological change promotes inflammation, reach the purpose of healing.
Method for using and consumption: this acupuncture points external application patch directly is affixed on the patient, changes once in per two days, and it is a course of treatment that logotype 6-16 pastes.
Through 100 routine patients have been done curative effect statistical observation, with local topical gynecological antiinflammatory patch, matched group compares with the Chinese and western medicine conservative treatment treatment group merely, and the result is following:
Table 1 compares for curative effect:
Group number The example number Cure rate Effective percentage Change other therapies after invalid
The treatment group 100 89 examples account for 89% 9 examples account for 98% 2 examples account for 2%
Matched group 80 70 examples account for 87.8% 8 examples account for 97.5% 2 examples account for 2.5%
Table 2 compared for treatment time:
Group number The example number The treatment pelvic inflammation The treatment dysmenorrhea The treatment uterine erosion Recurrence
The treatment group 100 6 hours % that come into effect of 60 examples 30 examples came into effect in 2 hours 6-30 days 2 example recurrences
Matched group 80 Came into effect in 24 hours Came into effect in 4 hours Came into effect in 24 hours 2 example recurrences
Prove that through 100 routine observed in detail this acupuncture points external application patch is compared with other therapies, and substantial characteristics and significant curative effect are arranged, and has the exclusivity in novelty, practicality and market, and the bright prospects of very strong vitality were arranged in medical domain, biology.
Use the treatment of acupuncture points external application patch, patient's abdomen is painful, tired, soreness of waist pain, and leukorrhagia all has clear improvement.Cure 64 examples one course of treatment, 8 examples that take a turn for the better, invalid 2 examples, total effective rate 98%, cure rate 89%, invalid 2%.
This acupuncture points external application patch local skin is not seen any allergy and other untoward reaction.Gynecological's Anti-inflammatory plaster is that natural wild plant is refined the analgesic ointment cream that forms, and is high to department of obstetrics and gynecology inflammation curative effect, safe and simple, without any side effects.More evident in efficacy than conventional anti-inflammatory analgetic oral medicine and enema therapy etc., have and cure the high advantage that does not rebound.
The specific embodiment
To combine embodiment that the present invention is described further below.
Embodiment 1
Choose raw material (gram) by following proportioning:
Herba Taraxaci 2 Folium et Cacumen Artemisiae Halodendri seeds 2 Radix Trichosanthis 3 Radix Et Rhizoma Rhei 3
Rhizoma Curcumae Longae 3 Bombyx Batryticatus 2 Cortex Phellodendris 2 Radix Scutellariaes 3.5
Radix Bupleuri 1 Olibanum 1.5 Myrrhas 1.5 Borneolum Syntheticums 1.5
Radix Paeoniae Rubra 2 Natrii Sulfas 4 Herba Menthaes 1.5 Radixs Angelicae Dahuricae 1.5
Herba Hedyotidis Diffusae 1, far infrared ceramic powder 0.1, magnetic powder 0.1, nanometer silver powder 0.1.
Its preparation method is following:
(1) at first get above-mentioned except that Olibanum, Myrrha, Borneolum Syntheticum, far infrared ceramic powder, magnetic powder, raw material the nanometer silver powder; Soaked 2-4 hour, decocte with water is 2 times again, after combining medicine is concentrated into 1:1 concentration; 95% the ethanol that adds 2 times stirs; Room temperature left standstill 48 hours, filtered waste, decompression recycling ethanol, and it is subsequent use to be concentrated into proportion and to be 1.23 extractum;
(2), it is subsequent use Olibanum, Myrrha, Borneolum Syntheticum powder to be broken into 130 order fine powders;
(3), with adding Olibanum, Myrrha, Borneolum Syntheticum fine powder, far infrared ceramic powder, magnetic powder, nanometer silver powder in the above-mentioned extractum that obtains, add and promptly obtain unguentum after medicinal transdermal agent and cataplasma plaster stroma stir, be the finished product plaster with cutting behind the dressing system cream.
Above-mentioned plaster stroma also can be selected medical pressure-sensitive adhesive for use.Described cataplasma and medical pressure-sensitive adhesive are buied by market.
Embodiment 2
The raw material of choosing by embodiment 1 proportioning; This method also comprises above-mentioned raw material is added water 1500-2500 milliliter; Endure before the heating to 800-1000 milliliter waste, continue decocting on the slow fire to the 550-600 milliliter, be condensed into cream and add the Chinese medicine transdermal agent; Add the plaster stroma mixing, be finished product with the cutting of dressing system cream.

Claims (5)

1. local acupuncture points external application patch of treatment gynecologic pelvic inflammatory disease is characterized in that it is made up of effective ingredient and conventional plaster stroma, wherein processes raw materials of effective components and consists of:
Herba Taraxaci 10-20 part, Folium et Cacumen Artemisiae Halodendri seed 15-20 part, Radix Trichosanthis 20-50 part,
Radix Et Rhizoma Rhei 30-45 part, Rhizoma Curcumae Longae 25-45 part, Bombyx Batryticatus 15-20 part,
Cortex Phellodendri 15-35 part, Radix Scutellariae 35-40 part, Radix Bupleuri 10-20 part,
Olibanum 5-15 part, Myrrha 5-15 part, Borneolum Syntheticum 5-15 part,
Radix Paeoniae Rubra 15-20 part, Natrii Sulfas 20-50 part, Herba Menthae 10-15 part,
Radix Angelicae Dahuricae 10-20 part, Herba Hedyotidis Diffusae 10-20 part, far infrared ceramic powder 0.5-2 part, magnetic powder 0.5-2 part, nanometer silver powder 0.5-2 part.
2. by the local acupuncture points external application patch of the described treatment pelvic inflammation of claim 1, wherein the weight proportion of each raw material is:
20 parts of Herba Taraxacis, 20 parts of Folium et Cacumen Artemisiae Halodendri seeds, 30 parts of Radix Trichosanthis, 30 parts of Radix Et Rhizoma Rhei,
30 parts in Rhizoma Curcumae Longae, 20 parts of Bombyx Batryticatus, 20 parts of Cortex Phellodendris, 35 parts of Radix Scutellariaes,
10 parts of Radix Bupleuri, 15 parts of Olibanums, 15 parts of Myrrhas, 15 parts of Borneolum Syntheticums,
20 parts of Radix Paeoniae Rubra, 40 parts in Natrii Sulfas, 15 parts of Herba Menthaes, 15 parts of the Radixs Angelicae Dahuricae,
10 parts of Herba Hedyotidis Diffusaes, 1 part of far infrared ceramic powder, 1 part of magnetic powder, 1 part of nanometer silver powder.
3. by claim 1 or the local acupuncture points external application patch of 2 described treatment pelvic inflammations, it is characterized in that described medicament is the external application putty-type.
4. a method for preparing that is used for the local acupuncture points external application patch of claim 3 treatment gynecologic pelvic inflammatory disease the steps include:
(1) at first gets above-mentioned raw material except that Olibanum, Myrrha, Borneolum Syntheticum, far infrared ceramic powder, magnetic powder, nanometer silver powder; Soaked 2-4 hour, decocte with water is 2 times again, after combining medicine is concentrated into 1:1 concentration; 95% the ethanol that adds 2 times stirs; Room temperature left standstill 48 hours, filtered waste, decompression recycling ethanol, and the extractum that is concentrated into proportion 1.23-1.28 is subsequent use;
(2) get Olibanum, Myrrha, that Borneolum Syntheticum powder is broken into 130 order fine powders is subsequent use;
(3) extractum with step 1 adds Olibanum, Myrrha, Borneolum Syntheticum fine powder, far infrared ceramic powder, magnetic powder, nanometer silver powder, adds to obtain unguentum after medicinal transdermal agent and plaster stroma stir, and is the finished product plaster with cutting behind the dressing system cream.
5. by the described method for preparing of claim 4; This method also comprises: above-mentioned raw material is added water 1500-2500 milliliter; Endure before the heating to 800-1000 milliliter waste, continue decocting on the slow fire to the 550-560 milliliter, be condensed into cream and add the Chinese medicine transdermal agent; Add the plaster stroma mixing, be finished product with the cutting of dressing system cream.
CN2012100546492A 2012-03-05 2012-03-05 Externally-applied patch of for local point to treat gynecologic pelvic inflammatory disease and preparation method thereof Pending CN102579982A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895325A (en) * 2012-09-28 2013-01-30 南昌大学 Traditional Chinese medicine bacteriostatic composition
CN104922570A (en) * 2015-06-07 2015-09-23 武文丽 Chinese medicine preparation and nursing method for treating cervical ectopy
CN106039200A (en) * 2016-05-24 2016-10-26 杨彦君 Local external application plaster for treating appendicitis and preparation method of plaster
CN109276669A (en) * 2018-09-17 2019-01-29 左耀武 A kind of intelligence system emplastrum and preparation method thereof for treating disease
CN109276689A (en) * 2018-12-10 2019-01-29 陕西太白山天然植物开发有限公司 A kind of external use plaster and preparation method thereof for treating dysmenorrhea

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CN1073876A (en) * 1992-12-18 1993-07-07 杨彦君 Typhlitic local external application medicine of a kind of treatment and manufacture method
CN1476884A (en) * 2003-07-09 2004-02-25 大连鸿宇药业有限公司 Inflammation-relieving plaster and its production method
CN1660293A (en) * 2004-12-23 2005-08-31 杨彦君 Medicine of regional external application for treating petvic inflammatory disease of women and preparing method
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CN101129899A (en) * 2007-09-24 2008-02-27 北京艺信堂医药研究所 Proprietary Chinese medicine for treating pelvic inflammatory disease
CN101301339A (en) * 2008-06-20 2008-11-12 牛天卓 Babu far infrared medicinal plaster for treating arthralgia and myalgia, and wind-cold syndrome and numbness
CN101336983A (en) * 2007-07-02 2009-01-07 广西壮族自治区花红药业股份有限公司 Oldenlandia and quality control method of preparation containing oldenlandia
CN101703668A (en) * 2009-10-23 2010-05-12 成莉 Nano-silver infrared antibacterial aloe fabric umbilical cord for preventing pelvic inflammation

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CN1073876A (en) * 1992-12-18 1993-07-07 杨彦君 Typhlitic local external application medicine of a kind of treatment and manufacture method
CN1476884A (en) * 2003-07-09 2004-02-25 大连鸿宇药业有限公司 Inflammation-relieving plaster and its production method
CN1660293A (en) * 2004-12-23 2005-08-31 杨彦君 Medicine of regional external application for treating petvic inflammatory disease of women and preparing method
CN101057959A (en) * 2007-03-16 2007-10-24 四川大学华西医院 Medicinal composition for treating derangement syndrome of small joints in lumbar spine and waist support
CN101336983A (en) * 2007-07-02 2009-01-07 广西壮族自治区花红药业股份有限公司 Oldenlandia and quality control method of preparation containing oldenlandia
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CN101301339A (en) * 2008-06-20 2008-11-12 牛天卓 Babu far infrared medicinal plaster for treating arthralgia and myalgia, and wind-cold syndrome and numbness
CN101703668A (en) * 2009-10-23 2010-05-12 成莉 Nano-silver infrared antibacterial aloe fabric umbilical cord for preventing pelvic inflammation

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895325A (en) * 2012-09-28 2013-01-30 南昌大学 Traditional Chinese medicine bacteriostatic composition
CN102895325B (en) * 2012-09-28 2014-07-09 南昌大学 Traditional Chinese medicine bacteriostatic composition
CN104013682A (en) * 2012-09-28 2014-09-03 南昌大学 Traditional Chinese medicine antibacteria composition for inhibiting micrococcus luteus
CN104013682B (en) * 2012-09-28 2015-11-25 南昌大学 A kind of Traditional Chinese medicine bacteriostatic composition suppressing micrococcus luteus
CN104922570A (en) * 2015-06-07 2015-09-23 武文丽 Chinese medicine preparation and nursing method for treating cervical ectopy
CN106039200A (en) * 2016-05-24 2016-10-26 杨彦君 Local external application plaster for treating appendicitis and preparation method of plaster
CN109276669A (en) * 2018-09-17 2019-01-29 左耀武 A kind of intelligence system emplastrum and preparation method thereof for treating disease
CN109276689A (en) * 2018-12-10 2019-01-29 陕西太白山天然植物开发有限公司 A kind of external use plaster and preparation method thereof for treating dysmenorrhea

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Application publication date: 20120718