CN1277552C - Five ingredients kaladana containing capsule and preparation technique thereof - Google Patents
Five ingredients kaladana containing capsule and preparation technique thereof Download PDFInfo
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- CN1277552C CN1277552C CNB200410073299XA CN200410073299A CN1277552C CN 1277552 C CN1277552 C CN 1277552C CN B200410073299X A CNB200410073299X A CN B200410073299XA CN 200410073299 A CN200410073299 A CN 200410073299A CN 1277552 C CN1277552 C CN 1277552C
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Abstract
The present invention relates to a five-component morning glory seed capsule which is a Chinese patent medicine preparation prepared from five Chinese medicinal plants of morning glory seed, pangolin scale, etc. for treating prostate hyperplasia and chronic prostatitis. The preparation method of the present invention is composed of processes of preparing powder by the pangolin scale., extracting volatile oil from fennel, packing the volatile oil, decocting the rest of Chinese herbal medicines, concentrating the Chinese herbal medicines to obtain clear paste, mixing soft materials, sieving the mixture to granulate, drying the granules for capsuling, etc. The present invention has the advantages of low production cost, simple preparation processes, stable quality, no toxic or side effect, convenient administration and significant curative effect.
Description
Affiliated technical field
Five ingredients kaladana containing capsule of the present invention and preparation technology thereof belong to pure compound Chinese medicinal preparation, relate in particular to treatment hyperplasia of prostate and chronic prostatitis pure Chinese medicinal preparation and preparation technology thereof.
Background technology
Hyperplasia of prostate and chronic prostatitis are the diseases of modal threat men's health.Hyperplasia of prostate claims prostate hyperplasia again, is male's senile disease, and prostatic hyperplasia was in various degree all arranged on man's pathology more than 40 years old, just engenders symptom later in 50 years old, and sickness rate increased gradually with the age.Along with the gentle healthy level of Chinese people people's livelihood running water improves constantly, the continuous improvement of medical condition, the corresponding prolongation of resident's average life, the sickness rate of primary disease significantly raises.According to domestic statistics, the old people 36~38% more than 50 years old has prostatic hyperplasia.Because prostatic hyperplasia causes urinary tract obstruction, urination disorder, wherein 60% acute urinary retention can occur, directly threatens renal function, and patient's life and health are brought serious harm.Hyperplasia of prostate accounts for Urology Surgery inpatient's 8~11%, is only second to lithangiuria and occupies second.Chronic prostatitis then is more common and multiple andropathy, accounts for Urology Surgery male patient's 35~40%, is mainly in 20~40 years old person between twenty and fifty.Be called by World Health Organization (WHO) " 21 century disease ".Generally chronic prostatitis is divided into bacillary at present and aseptic two classes, but no matter bacillary and aseptic both have the sings and symptoms of chronic prostatitis, prostate all has certain abnormal change, and morbidity slowly, symptom is various, clinical efficacy is not good enough, so that course of disease delay, prolonged difficulty are more, even cause sexual impotence, many secondary diseases such as sterile, cause very big stress even pessimism to the patient.
Hyperplasia of prostate and chronic prostatitis are as chronic disease, difficult disease, many families that cure have all carried out theoretical and clinical exploration, but, clear and definite hyperplasia of prostate and chronic prostatitis belong to deficiency in origin and mark reality, but it is real to mark, and it is stagnant with damp-heat in lower-JIAO, the resistance of the Liver Channel mental disorder stasis of blood, be jammed and do not see as yet for the report of main pathogenesis in the born of the same parents, because the patient age of hyperplasia of prostate is bigger than normal, and often with diseases such as the heart, brain, kidneys, so patient's treatment that can not undergo surgery is arranged greatly.Expectant treatment has effects such as estrin treatment, α adrenergic receptor blocker therapy (as Phenoxybenzamine) and local injection therapy all difficult fully up to expectations, for stagnant at damp-heat in lower-JIAO, the resistance of the Liver Channel mental disorder stasis of blood, the born of the same parents of being jammed are interior for mainly the hyperplasia of prostate of pathogenesis and the novel Chinese patent medicine of chronic prostatitis provide the very big market.
Summary of the invention
The objective of the invention is: select for use five kinds of Chinese crude drugs to form prescription, production and processing becomes to have the herbal mixture capsule that rushes down damp and hot, the stasis of blood of reducing phlegm, regulating the flow of QI to relieve constipation function, be used for oral, treatment hyperplasia of prostate and chronic prostatitis property inflammation, and reach safety, effectively, low production cost, have no side effect.
To achieve these goals, the technical scheme taked of five ingredients kaladana containing capsule of the present invention and preparation technology thereof is: five ingredients kaladana containing capsule prescription medicine is made up of 27.6% Semen Pharbitidis, 13.8% Squama Manis, 13.8% Fructus Toosendan, 27.6% Radix Astragali, 13.8% Fructus Foeniculi and 3.4% beta-schardinger dextrin-adjuvant; The preparation technology of five ingredients kaladana containing capsule is first Squama Manis crushing screening after 60 ℃ of oven dry, and it is standby to get 1/2 recipe quantity fine powder; Fructus Foeniculi adds the water distillation, collects volatile oil, and is standby with beta-cyclodextrin inclusion compound; With the Radix Astragali, Semen Pharbitidis, Fructus Toosendan, residue Squama Manis and Fructus Foeniculi medicinal residues, decoct with water 3 times, residual filtrate after merging 3 filtrates and collecting volatile oil, being evaporated to relative density is the clear paste of 1.28~1.30 (60 ℃), adds the Squama Manis fine powder, with the Benexate Hydrochloride mixing, granulate, the capsule of packing into No. 0 is made 1000, promptly get patent medicine, oral for the patient.According to the Chinese medicine theory, in this prescription, the relieving constipation of Semen Pharbitidis diuretic is eliminated the phlegm by drink, and the deficiency of vital energy that dewaters is swollen, and controlling the mass beside the umbilicus air parcel is monarch drug; The Squama Manis blood circulation promoting and dispersing pathogen accumulation, eliminating carbuncle is burst hard, and qualcomm meridian, subduing inflammation are ministerial drug; Fructus Toosendan is soothing the liver to expel the heat-evil, and promoting the circulation of QI to relieve pain are controlled the hernia abdominal mass, removes pain gas, diuresis, and logical large intestine is controlled the kidney irritability and is hindered, Radix Astragali benefiting qi and raising yang, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening helps the gas strengthening bone and muscle, puts on flesh and enriches blood, and kidney tonifying gas goes flesh heat, and two medicines are adjuvant drug altogether; The Fructus Foeniculi the kidney warming warms up liver, promoting the circulation of QI to relieve pain, remove hernia, warm public region, strengthening bone and muscle is a messenger drug, and all medicines are collaborative plays the function of rushing down damp and hot, the stasis of blood of reducing phlegm, regulating the flow of QI to relieve constipation altogether, and the verification subordinate is burnt damp and hot stagnant, the resistance of the Liver Channel mental disorder stasis of blood has long-pending hyperplasia of prostate of thick fur and patients with chronic prostatitis that significant curative effect is arranged.According to modernization of Chinese medicine theory, various trace elements and 16 kinds of free amino acids and the multiple ethereal oil and four in the Fructus Foeniculi are distinguished the flavor of in the poly-Squama Manis in this preparation, and water-soluble substances is an one in the Chinese herbal medicine, promote the body enterokinesia, antiulcer, inhibiting bacteria and diminishing inflammation promotes the swollen protein of liver to upgrade, effectively treat hyperplasia of prostate and chronic prostatitis, contain ethereal oil compositions such as antimicrobial myrcene, limonene in the preparation, impel the quality of the pharmaceutical preparations stable, long shelf-life.
Five ingredients kaladana containing capsule of the present invention and preparation technology's thereof beneficial effect is: five kinds of raw material of Chinese medicine wide material sources in the prescription, and cheap, all have no side effect, processing technique is easy, low production cost, steady quality, convenient oral, treatment hyperplasia of prostate and chronic prostatitis have outstanding curative effect.
The specific embodiment
1. best effectively prescription amount, degree such as following table of each prescription in the five ingredients kaladana containing capsule:
The Chinese crude drug title | Semen Pharbitidis | Squama Manis | Fructus Toosendan | The Radix Astragali | Fructus Foeniculi | Beta-schardinger dextrin- | Add up to |
Formula ratio (gram) | 276 | 138 | 138 | 276 | 138 | 34 | 1000 |
Content (%) | 27.6 | 13.8 | 13.8 | 27.6 | 13.8 | 3.4 | 100 |
2. five ingredients kaladana containing capsule preparation technology:
1. get after the remove impurity of five kinds of Chinese crude drug well sifteds standby by the prescription weighing;
2. Squama Manis was pulverized 80 mesh sieves after 60 ℃ of oven dry, got behind half recipe quantity fine powder standby respectively with second half coarse powder;
3. Fructus Foeniculi is added 5 times of water distillations, collect volatile oil and filter, filtrate and beta-schardinger dextrin-are adopted the electronic paddling process enclose of saturated aqueous solution, it is standby respectively to get bag and thing and residual filter thing;
4. the Radix Astragali, Semen Pharbitidis, Fructus Toosendan and remaining Squama Manis and Fructus Foeniculi medicinal residues are added 5 times of decoctings and boil 3 times, each 1 hour, merge 3 times filtrate, add the residual filter thing of Fructus Foeniculi in one, the clear paste that is evaporated to relative density and is 1.28~1.30 (60 ℃) is standby;
5. at last standby Squama Manis powder, standby beta-schardinger dextrin-bag and thing are added and puddle in the standby clear paste evenly, make soft material, and cross 16 mesh sieves and granulate, through 60 ℃ of oven dry, No. 0 capsule of packing into gets patent medicine.
3. usage and consumption: oral, 3 times on the one, each 4.
Claims (2)
1, a kind of five ingredients kaladana containing capsule is characterized in that raw material consists of 27.6% Semen Pharbitidis, 13.8% Squama Manis, 13.8% Fructus Toosendan, 27.6% Radix Astragali, 13.8% Fructus Foeniculi and 3.4% beta-schardinger dextrin-.
2, the preparation technology of five ingredients kaladana containing capsule according to claim 1 is characterized in that: earlier Squama Manis crushing screening after 60 ℃ of oven dry, it is standby to get 1/2 recipe quantity fine powder; Fructus Foeniculi adds the water distillation, collects volatile oil, and is standby with beta-cyclodextrin inclusion compound; With the Radix Astragali, Semen Pharbitidis, Fructus Toosendan, residue Squama Manis and Fructus Foeniculi medicinal residues, decoct with water 3 times, residual filtrate after merging 3 filtrates and collecting volatile oil, relative density is 1.28~1.30 clear paste when being evaporated to 60 ℃, add the Squama Manis fine powder,, granulate with the Benexate Hydrochloride mixing, the capsule of packing into No. 0 promptly gets patent medicine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB200410073299XA CN1277552C (en) | 2004-11-22 | 2004-11-22 | Five ingredients kaladana containing capsule and preparation technique thereof |
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CNB200410073299XA CN1277552C (en) | 2004-11-22 | 2004-11-22 | Five ingredients kaladana containing capsule and preparation technique thereof |
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CN1634363A CN1634363A (en) | 2005-07-06 |
CN1277552C true CN1277552C (en) | 2006-10-04 |
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CNB200410073299XA Expired - Fee Related CN1277552C (en) | 2004-11-22 | 2004-11-22 | Five ingredients kaladana containing capsule and preparation technique thereof |
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Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100372546C (en) * | 2005-12-31 | 2008-03-05 | 张强 | Chinese medicinal preparation for treating prostatitis and its preparation method |
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Granted publication date: 20061004 Termination date: 20091222 |