CN1276714C - Skin disinfectant for external use prepn process - Google Patents
Skin disinfectant for external use prepn process Download PDFInfo
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- CN1276714C CN1276714C CNB021114692A CN02111469A CN1276714C CN 1276714 C CN1276714 C CN 1276714C CN B021114692 A CNB021114692 A CN B021114692A CN 02111469 A CN02111469 A CN 02111469A CN 1276714 C CN1276714 C CN 1276714C
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B1/00—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission
- H04B1/69—Spread spectrum techniques
- H04B1/707—Spread spectrum techniques using direct sequence modulation
- H04B1/7097—Interference-related aspects
- H04B1/711—Interference-related aspects the interference being multi-path interference
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B1/00—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission
- H04B1/69—Spread spectrum techniques
- H04B1/707—Spread spectrum techniques using direct sequence modulation
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B2201/00—Indexing scheme relating to details of transmission systems not covered by a single group of H04B3/00 - H04B13/00
- H04B2201/69—Orthogonal indexing scheme relating to spread spectrum techniques in general
- H04B2201/707—Orthogonal indexing scheme relating to spread spectrum techniques in general relating to direct sequence modulation
- H04B2201/70701—Orthogonal indexing scheme relating to spread spectrum techniques in general relating to direct sequence modulation featuring pilot assisted reception
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04J—MULTIPLEX COMMUNICATION
- H04J13/00—Code division multiplex systems
- H04J13/0077—Multicode, e.g. multiple codes assigned to one user
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Abstract
The present invention provides a skin disinfectant for external use and a preparation method thereof. The preparation method is characterized in that the skin disinfectant is prepared from the aromatic essential oil of a plurality of natural vegetables and the ethanol leaching liquor of a plurality of natural Chinese herbal medicines by mixing and purification, wherein the aromatic essential oil is prepared from natural plants, such as wintergreen oil, litsea cubeba oil, fragrant citrus oil, peppermint oil, borneol, camphor, oxybenzoic acid, jasmine essence, menthol and eucalyptus oil, by mixing and purification; the ethanol leaching liquor is prepared from natural Chinese herbal medicines, such as amur corktree bark, dahurian angelica, rhizoma Ligustici Wallichi, manchurian wildginger, densefruit pittany root-bark, cablin patchouli herb, japanese ampelopsis root, honeycomb of paper wasps, Chinese ligusticum rhizome, myrrh, frankincense and lightyellow sophora root, by mixing and purification. The skin disinfectant for external use of the present invention can effectively eliminate the inflammation and swelling caused by mosquito stings and insect bites, can effectively eliminate miliaria or point miliaria, has remarkable effects on the prevention or relief of heatstroke, carsickness, headache, chest distress and spirit ennui, and has no toxic or side effect of allergies on skin.
Description
Technical field
The present invention relates to a kind of biologic product that is used for preventing and treating diseases, relate in particular to a kind of skin disinfectant for external use and preparation method thereof.
Background technology
Along with global climate warms and the deterioration of environmental pollution, particularly the kind of invasive organism and procreation speed are all in continuous rising for various microorganisms, and the incidence of disease of the various disease of skin due to the human body skin that causes thus is infected also increases rapidly thereupon; Human body skin by mosquito bite and insect bite after, swollen itching difficult the taboo, scratch back skin again very easily infection inflammation so that dense swollen; In season in summertime, human body is subjected to the extremely hot attack of high temperature, and resistance against diseases descends, and spirit is burnout very easily, and suffers heatstroke easily, catches a cold, and particularly children easily give birth to prickly heat or point and prickly heat in summer, have a strong impact on their growing up healthy and sound, and also makes many head of a family's headaches endlessly.To this, press on the market a kind of can arousing brain, raising spirit, the analgesic heat of warding off, prevention hot summer weather burnout, cold headache, dermatitis is swollen behind the mosquito bite and insect bite that can stop again very itches, prevents skin infection, and interest rebate of itching, and skin there is not the high-efficiency multi-function skin disinfectant for external use of hypersensitivity toxic and side effect.The external preparation for skin pharmacopoeia class that provides in the market is a lot, but its curative effect often presents unicity, and some of them also have the hypersensitivity toxic and side effect to skin.
Summary of the invention
Purpose of the present invention, be to provide a kind of can arousing brain, raising spirit, analgesic diffusing heat, prevention tired mind, cold headache, the dermatitis that can stop again behind the mosquito bite and insect bite is swollen very itches, prevents skin infection, and the interest rebate prickly heat, and skin there is not the multi-functional skin disinfectant for external use of a kind of efficiency natural of hypersensitivity toxic and side effect.
The object of the present invention is achieved like this: a kind of skin disinfectant for external use, be characterized in: mix refining forming by the volatile oil of some kinds of natural plants and the alcohol extract of some kinds of natural Chinese medicinal herb, the volatile oil of described some kinds of natural plants is made with extra care and is got by aromatic oil, the aromatic mixing of some kinds of natural plants; The alcohol extract of described some kinds of natural Chinese medicinal herb mixes refining by some kinds of natural Chinese medicinal herb and gets.
Above-mentioned a kind of skin disinfectant for external use, wherein: the aromatic oil of described some kinds of natural plants, the composition of aromatic and proportioning (weight portion) are:
Methyl salicylate 0.1～5.0 litsea cubeba oil 5.0～25.0
Petit grain oil 0.5～8.0 peppermint oil 10.0～50.0
Borneol 5.0～25.0 camphors 5.0～20.0
Salicylic acid 0.5～2.5 jasmine flower essence 0.5～5.0
Menthol 5.0～30.0 eucalyptus oils 5.0～25.0
Above-mentioned a kind of skin disinfectant for external use, wherein: the composition of described some kinds of natural Chinese medicinal herb and proportioning (weight portion) are:
Golden cypress 5～40 roots of Dahurain angelica 5～30
Ligusticum wallichii 3～15 roots of Chinese wild ginger 5～40
The root bark of shaggy-fruited dittany 5～40 Pogostemon cablin 5～30
Radix ampelopsis 5～40 nidus vespaes 5～30
Jehol Ligusticum Rhizome 5～30 myrrhs 5～30
Frankincense 5～30 kuh-sengs 5～40
A kind of preparation method of skin disinfectant for external use is characterized in: described preparation method's step is:
The first, aromatic oil, the aromatic of some kinds of natural plants are pressed following proportioning (weight portion):
Methyl salicylate 0.1～5.0 litsea cubeba oil 5.0～25.0
Petit grain oil 0.5～8.0 peppermint oil 10.0～50.0
Borneol 5.0～25.0 camphors 5.0～20.0
Salicylic acid 0.5～2.5 jasmine flower essence 0.5～5.0
Menthol 5.0～30.0 eucalyptus oils 5.0～25.0
Weighing, mixing;
The second, the mixture with the step 1 gained adds saturated liquor natrii hypochloritis in the ratio that per 100 grams add 0.2 milliliter of saturated liquor natrii hypochloritis, shakes up, and leaves standstill under the room temperature 28～32 hours;
Three, with the solution of step 2 gained set by step the ratios that per 100 grams add 1 milliliter of 5% hypo solution that calculate the weight add 5% hypo solution, shake up, left standstill under the room temperature 28～32 minutes;
Four, with the water liquid of the solution sucking-off bottom of step 3 gained, give up, upper oil phase liquid be volatile oil;
Five, some kinds of natural Chinese medicinal herb are pressed following proportioning (weight portion):
Golden cypress 5～40 roots of Dahurain angelica 5～30
Ligusticum wallichii 3～15 roots of Chinese wild ginger 5～40
The root bark of shaggy-fruited dittany 5～40 Pogostemon cablin 5～30
Radix ampelopsis 5～40 nidus vespaes 5～30
Jehol Ligusticum Rhizome 5～30 myrrhs 5～30
Frankincense 5～30 kuh-sengs 5～40
The weighing mixing also breaks into meal;
Six, the meal of step 5 gained is added ethanol by 3～5 times of amounts of its weight and flood, soaked at least 3 days under the room temperature;
Seven, the soak with the step 6 gained filters, and removes the dregs of a decoction, gets the Chinese herbal medicine alcohol extract;
Eight, 1: 1 by volume mixing of Chinese herbal medicine alcohol extract of obtaining of volatile oil that step 4 is obtained and step 7 places that low temperature environment is quiet to be put 24～36 hours;
Nine, the solution that step 8 is obtained takes out fast and filters, and gets yellow clear and bright liquid, is a kind of skin disinfectant for external use.
The preparation method of above-mentioned a kind of skin disinfectant for external use, wherein: in described step 6, described ethanol is 95% medical ethanol.
The preparation method of above-mentioned a kind of skin disinfectant for external use, wherein: in described step 8, described low temperature is 0～4 ℃ of scope.
A kind of skin disinfectant for external use of the present invention is because employing has sterilization anti-inflammatory, expelling wind and clearing away cold, analgesic refining the forming of aromatic, aromatic oil and natural Chinese medicinal herb of warding off the multiple natural plants of heat, sensible inducing resuscitation effect, and it is swollen therefore to use it can eliminate the caused inflammation of mosquito bite and insect bite effectively; Interest rebate prickly heat or point and prickly heat effectively; Spread upon on the skin with it, have comfortable refrigerant no greasy feeling, mosquito dare not bite in smearing around the position tens of centimeters zones, and mosquito bite and insect bite is had tangible repellent action, and the repellent time is more than 3 hours; If the mosquito bite and insect bite place play occurs and itches scorchingly swollen, after smearing with it, itching about half an hour and ending swollen disappearing, calm down as usual; Be applied in the skin district of growing thickly of itching with it, the son even the purulence head is itched, the incrustation that disappears of also can about 2 hours, itching, effect is remarkable; Be applied in head temple district, frons or philtrum zone with it, by it is infiltrated skin or hear its fragrance to prevention or remove heatstroke, carsickness, headache, uncomfortable in chest, tired mind has remarkable result, and skin is not had the hypersensitivity toxic and side effect.
Embodiment
By the description of following some embodiment to a kind of skin disinfectant for external use of the present invention, can further understand purpose of the present invention, characteristics and advantage:
Embodiment one:
Get methyl salicylate 1.0 gram, litsea cubeba oil 30.0 grams, petit grain oil 3.0 grams, peppermint oil 20.0 grams, borneol 10.0 grams, camphor 10.0 grams, salicylic acid 2.0 grams, jasmine flower essence 2.0 grams, menthol 10.0 grams, eucalyptus oil 12.0 grams and be mixed into solidliquid mixture, add 0.2 milliliter of saturated liquor natrii hypochloritis, shake up, left standstill under the room temperature 30 hours, add 1 milliliter of 5% hypo solution then, shake up, the water liquid of sucking-off bottom after 30 minutes, give up, upper oil phase liquid is that volatile oil is standby;
Get golden cypress 35 gram, the root of Dahurain angelica 10 grams, Ligusticum wallichii 10 grams, the root of Chinese wild ginger 15 grams, the root bark of shaggy-fruited dittany 15 grams, Pogostemon cablin 10 grams, radix ampelopsis 20 grams, process nidus vespae 20 grams, Jehol Ligusticum Rhizome 10 grams, myrrh 10 grams, frankincense 10 grams, kuh-seng 15 grams mix and break into meal, add 95% medical ethanol and flood for 500 milliliters, soaked 3 days under the room temperature; It is standby to leach alcohol extract.The dregs of a decoction add 500 milliliter of 95% medical ethanol again and soak, leach ethanol secondary leaching liquor give over to soak next time medicinal.
With volatile oil and 1: 1 by volume mixing of Chinese herbal medicine alcohol extract of above-mentioned gained, place 0～4 ℃ quiet the putting 30 hours of refrigerator; Take out with quick filter paper and filter, filtrate is a kind of skin disinfectant for external use product of the present invention.
Embodiment two:
Get methyl salicylate 0.1 gram, litsea cubeba oil 5.0 grams, petit grain oil 0.5 gram, peppermint oil 10.0 grams, borneol 5.0 grams, camphor 5.0 grams, salicylic acid 0.5 gram, jasmine flower essence 0.5 gram, menthol 5.0 grams, eucalyptus oil 5.0 grams and be mixed into solidliquid mixture, add 0.1 milliliter of saturated liquor natrii hypochloritis, shake up, left standstill under the room temperature 30 hours, add 0.5 milliliter of 5% hypo solution then, shake up, the water liquid of sucking-off bottom after 30 minutes, give up, upper oil phase liquid is that volatile oil is standby;
Get golden cypress 5 gram, the root of Dahurain angelica 5 grams, Ligusticum wallichii 3 grams, the root of Chinese wild ginger 5 grams, the root bark of shaggy-fruited dittany 5 grams, Pogostemon cablin 5 grams, radix ampelopsis 5 grams, process nidus vespae 5 grams, Jehol Ligusticum Rhizome 5 grams, myrrh 5 grams, frankincense 5 grams, kuh-seng 5 grams mix and break into meal, add 95% medical ethanol and flood for 200 milliliters, soaked 3 days under the room temperature; It is standby to leach alcohol extract.The dregs of a decoction add 200 milliliter of 95% medical ethanol again and soak, leach ethanol secondary leaching liquor give over to soak next time medicinal.
With volatile oil and 1: 1 by volume mixing of Chinese herbal medicine alcohol extract of above-mentioned gained, place 0～4 ℃ quiet the putting 30 hours of refrigerator; Take out with quick filter paper and filter, filtrate is a kind of skin disinfectant for external use product of the present invention.
Embodiment three:
Get methyl salicylate 5.0 gram, litsea cubeba oil 25.0 grams, petit grain oil 8.0 grams, Peppermint Oil 50 .0 gram, borneol 25.0 grams, camphor 20.0 grams, salicylic acid 2.5 grams, jasmine flower essence 5.0 grams, menthol 30.0 grams, eucalyptus oil 25.0 grams and be mixed into solidliquid mixture, add 0.5 milliliter of saturated liquor natrii hypochloritis, shake up, left standstill under the room temperature 30 hours, add 2 milliliters of 5% hypo solutions then, shake up, the water liquid of sucking-off bottom after 30 minutes, give up, upper oil phase liquid is that volatile oil is standby;
Get golden cypress 40 gram, the root of Dahurain angelica 30 grams, Ligusticum wallichii 15 grams, the root of Chinese wild ginger 40 grams, the root bark of shaggy-fruited dittany 40 grams, Pogostemon cablin 30 grams, radix ampelopsis 40 grams, process nidus vespae 30 grams, Jehol Ligusticum Rhizome 30 grams, myrrh 30 grams, frankincense 30 grams, kuh-seng 40 grams mix and break into meal, add 95% medical ethanol and flood for 1000 milliliters, soaked 3 days under the room temperature; It is standby to leach alcohol extract.The dregs of a decoction add 1000 milliliter of 95% medical ethanol again and soak, leach ethanol secondary leaching liquor give over to soak next time medicinal.
With volatile oil and 1: 1 by volume mixing of Chinese herbal medicine alcohol extract of above-mentioned gained, place 0～4 ℃ quiet the putting 30 hours of refrigerator; Take out with quick filter paper and filter, filtrate is a kind of skin disinfectant for external use product of the present invention.
A kind of skin disinfectant for external use of the present invention is through relevant department's test and check, and the result is as follows:
1, small white mouse rolling ring exercise test
Small white mouse is put in the rolling ring that automatic counting is housed, and it is 30 liters glass jar that frame linking places volume together, puts 10 milliliter of 45% ethanol liquid in the cylinder, covers the glass lid, calculates 24 hours rolling ring number of small white mouse, in contrast.Normally raised then one day, and in cylinder, added 10 milliliters of a kind of skin disinfectant for external use of the present invention, calculate 24 hours rolling ring number of small white mouse.Result of the test such as the table 1 of 10 small white mouses of statistics:
Table 1 small white mouse rolling ring exercise test result
| Reagent | 45% ethanol | A kind of skin disinfectant for external use of the present invention |
| The number of turns | 11360±6178 | 13527±6644 |
| P＜0.01 |
The result shows that 24 hour the rolling ring number of small white mouse in the environment of a kind of skin disinfectant for external use of the present invention is than increased by 19.1% in 45% ethanol environment.
2, small white mouse anoxia enduring time-to-live test
Get 20 small white mouses, male and female are regardless of, and are divided into two groups at random, and placing volume respectively is 5 liters glass jar.Wherein hang the cotton balls that a usefulness a kind of skin disinfectant for external use of the present invention soaks under the cylinder cap of a cylinder, hang the cotton balls that a usefulness 45% ethanol soaks under the cylinder cap of another cylinder.Seal cover tight (smearing glass cylinder edge) with vaseline.Observe the anoxia enduring time-to-live of small white mouse, the result is listed as table 2:
Table 2 small white mouse anoxia enduring time-to-live result of the test
| Reagent | 45% ethanol | A kind of skin disinfectant for external use of the present invention |
| Time-to-live (hour) | 35.5±6.7 | 54.5±8.9 |
| P＜0.01 |
The result shows that the anoxia enduring time-to-live of small white mouse in the environment of a kind of skin disinfectant for external use of the present invention is than prolonged 53.6% in 45% ethanol environment.
3, eliminate the scorching swollen test of due to mosquito bites
Tried patient's accumulative total 186 examples, wherein infant's 46 examples.The swollen bubble of the inflammation that experimenter's arm and shank occur differing in size after by bite by mosquitos is coated a kind of skin disinfectant for external use of the present invention, massage affected part, a kind of skin disinfectant for external use of the present invention in the overcoating again.End to itch in half an hour swollen disappear serve as significantly effectively, itching in 1 hour to end swollenly disappears for effectively result of the test such as table 3:
Table 3 a kind of skin disinfectant for external use of the present invention is eliminated the scorching swollen result of the test of due to mosquito bites
| Effect | Significantly effectively | Effectively | Invalid * |
| The example number | 148 | 29 | 9 |
| Percentage | 79.6％ | 15.6％ | 4.8％ |
* the nonresponder is because the breath Trane amount of smearing is very few, and only is coated with once.Smear again after the correct using method of announcement effectively.
4, cephalocathartic inducing resuscitation test
Experimenter's number accumulative total 56 examples are tested when summer is hot and are carried out in season.When sleepy phenomenon appears in the experimenter, promptly smear temple, forehead position and upper lip position with a kind of skin disinfectant for external use of the present invention.Observation sleepy disappearance person in half an hour is effective; Halfhour sleepy for the previous period the disappearance, the back segment time is appeared again existing person again for improving; Surpass and still have half an hour sleepy person for invalid.Result of the test such as table 4:
Table 4 a kind of skin disinfectant for external use cephalocathartic inducing resuscitation result of the test of the present invention
| Effect | Effectively | Improve | Invalid |
| The example number | 21 | 17 | 18 |
| Percentage | 37.5％ | 30.4％ | 32.1％ |
5, the repellent action of mosquito is tested
Method of testing ℃ is carried out .T:28.5 ℃, R:68% by SOP351-353 regulation.Test result such as table 5:
Table 5 a kind of skin disinfectant for external use of the present invention is to the repellent action of mosquito
| Group | Test mosquito kind | Test mosquito number (only) | Method of testing (3 * 4 centimetres of arms) | The result (hour) 1234 | Criterion |
| 1 | Aedes albopictus | 1500 | Attack is observed | 0 0 1 5 | Effectively, qualified more than 3 hours |
| 2 | Aedes albopictus | 1500 | Attack is observed | 0 0 1 7 | |
| 3 | Aedes albopictus | 1500 | Attack is observed | 0 0 0 1 1 | |
| Add up to | 4500 | 0 0 2 2 3 |
6, a kind of skin disinfectant for external use stoste of the present invention was to Candida albicans effect 1 minute, and killing rate is 99.98%.
7, a kind of skin disinfectant for external use stoste of the present invention through 54 ℃ deposit 14 days after, to Candida albicans effect 2 minutes, killing rate was 99.96%.
8, a kind of skin disinfectant for external use stoste of the present invention wiping skin effect 1 minute on hand is 99.30% to the killing rate of natural bacteria on hand, and residual bacterium amount meets the requirement of GB15980-1995.
9,1: 1 dilution of a kind of skin disinfectant for external use of the present invention was to colon bacillus effect 1 minute, and killing rate is 99.96%, and to staphylococcus aureus effect 1 minute, killing rate was 99.90%.
10,1: 10 dilution of a kind of skin disinfectant for external use of the present invention was to staphylococcus aureus effect 1 minute, and killing rate is 99.90%, and to Escherichia coli effect 3 minutes, killing rate was 99.94%.
11,1: 8 dilution of a kind of skin disinfectant for external use of the present invention acts on 10 minutes to the staphylococcus aureus that contains 0%, 25%, 50% calf serum, and killing rate is respectively 99.99%, 89.93% and 73.06%.The existence of calf serum has slight effect to the sterilization effect of a kind of skin disinfectant for external use of the present invention.
12, acute oral toxicity test: tried male and female chmice acute per os LD
50Value and 95% doubly limit is 5.01 (3.44～7.30) g/Kgb.wt, the nontoxic level in true border.
13, acute eye irritation test: being tried the acute eye irritation score index peak of rabbit is 6.5, belongs to subexcite.
14, acute skin irritation test: being tried rabbit acute skin irritation reaction integrated value is 0.5, belongs to subexcite.
15, PCEMNR micronucleus test: dosage reaches 2.50g/Kgb.wt, does not detect the male and female PCEMNR is caused the micronucleus effect.
16, mouse cumulative toxicity test: successive administration is after 20 days, the insufficient yet half of animal dead, K＞5, the property accumulated a little less than this is tried thing and is.
In sum, a kind of skin disinfectant for external use of the present invention for prevention and treatment mosquito bite and insect bite, only move back prickly heat, for arousing brain, raising spirit and the analgesic heat of warding off remarkable result is arranged all, and without the anaphylaxis toxic and side effect, therefore very applicable.
Claims (3)
1, a kind of skin disinfectant for external use is characterized in that: mix refining forming by the volatile oil of natural plants and the alcohol extract of natural Chinese medicinal herb, the volatile oil of described natural plants is made with extra care and is got by aromatic oil, the aromatic mixing of natural plants; The alcohol extract of described natural Chinese medicinal herb mixes refining by natural Chinese medicinal herb and gets;
The aromatic oil of described natural plants, the composition of aromatic and proportioning weight portion are:
Methyl salicylate 0.1～5.0 litsea cubeba oil 5.0～25.0
Petit grain oil 0.5～8.0 peppermint oil 10.0～50.0
Borneol 5.0～25.0 camphors 5.0～20.0
Salicylic acid 0.5～2.5 jasmine flower essence 0.5～5.0
Menthol 5.0～30.0 eucalyptus oils 5.0～25.0;
The composition of described natural Chinese medicinal herb and proportioning weight portion are:
Golden cypress 5～40 roots of Dahurain angelica 5～30
Ligusticum wallichii 3～15 roots of Chinese wild ginger 5～40
The root bark of shaggy-fruited dittany 5～40 Pogostemon cablin 5～30
Radix ampelopsis 5～40 nidus vespaes 5～30
Jehol Ligusticum Rhizome 5～30 myrrhs 5～30
Frankincense 5～30 kuh-sengs 5～40.
2, a kind of preparation method of skin disinfectant for external use is characterized in that: described preparation method's step is:
The first, aromatic oil, the aromatic of natural plants are pressed following proportioning weight portion:
Methyl salicylate 0.1～5.0 litsea cubeba oil 5.0～25.0
Petit grain oil 0.5～8.0 peppermint oil 10.0～50.0
Borneol 5.0～25.0 camphors 5.0～20.0
Salicylic acid 0.5～2.5 jasmine flower essence 0.5～5.0
Menthol 5.0～30.0 eucalyptus oils 5.0～25.0
Weighing, mixing;
The second, the mixture with the step 1 gained adds saturated liquor natrii hypochloritis in the ratio that per 100 grams add 0.2 milliliter of saturated liquor natrii hypochloritis, shakes up, and leaves standstill under the room temperature 28～32 hours;
Three, with the solution of step 2 gained set by step the ratios that per 100 grams add 1 milliliter of 5% hypo solution that calculate the weight add 5% hypo solution, shake up, left standstill under the room temperature 28～32 minutes;
Four, with the water liquid of the solution sucking-off bottom of step 3 gained, give up, upper oil phase liquid be volatile oil;
Five, natural Chinese medicinal herb is pressed following proportioning weight portion:
Golden cypress 5～40 roots of Dahurain angelica 5～30
Ligusticum wallichii 3～15 roots of Chinese wild ginger 5～40
The root bark of shaggy-fruited dittany 5～40 Pogostemon cablin 5～30
Radix ampelopsis 5～40 nidus vespaes 5～30
Jehol Ligusticum Rhizome 5～30 myrrhs 5～30
Frankincense 5～30 kuh-sengs 5～40
The weighing mixing also breaks into meal;
Six, the meal of step 5 gained is added ethanol by 3～5 times of amounts of its weight and flood, soaked at least 3 days under the room temperature;
Seven, the soak with the step 6 gained filters, and removes the dregs of a decoction, gets the Chinese herbal medicine alcohol extract;
Eight, 1: 1 by volume mixing of Chinese herbal medicine alcohol extract of obtaining of volatile oil that step 4 is obtained and step 7 places 0～4 ℃ of quiet putting 24～36 hours of environment;
Nine, the solution that step 8 is obtained takes out fast and filters, and gets yellow clear and bright liquid, is a kind of skin disinfectant for external use.
3, the preparation method of a kind of skin disinfectant for external use according to claim 2 is characterized in that: in described step 6, described ethanol is 95% medical ethanol.
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| CNB021114692A CN1276714C (en) | 2002-04-24 | 2002-04-24 | Skin disinfectant for external use prepn process |
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| CNB021114692A CN1276714C (en) | 2002-04-24 | 2002-04-24 | Skin disinfectant for external use prepn process |
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| CN1452868A CN1452868A (en) | 2003-11-05 |
| CN1276714C true CN1276714C (en) | 2006-09-27 |
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| CN100366235C (en) * | 2006-01-25 | 2008-02-06 | 刘晓芸 | Skin physiological maintenance oil for male |
| CN1965945B (en) * | 2006-11-06 | 2010-11-03 | 林育芳 | Tincture having ageratum and mint for treating heat rash |
| CN101473857B (en) * | 2008-12-26 | 2012-10-24 | 黄付兴 | Chinese medicine environmental medical science treating agent first medical preparation |
| CN102349991A (en) * | 2011-05-29 | 2012-02-15 | 王红芳 | Composition for killing virus and preventing influenza and cold prevention plaster prepared by composition |
| CN102578169B (en) * | 2012-01-11 | 2013-09-18 | 蔡葵荣 | Chinese herb biological disinfectant |
| CN102836351B (en) * | 2012-09-03 | 2014-09-24 | 皖南医学院 | Skin care essential balm for relieving itching and diminishing swelling and preparation method thereof |
| CN103948953A (en) * | 2014-03-24 | 2014-07-30 | 李勇 | Air refreshing agent having refreshing effect |
| CN105456808B (en) * | 2016-01-27 | 2016-08-24 | 孙文洁 | Gynaecopathia external prescription |
| CN105561005B (en) * | 2016-01-27 | 2016-08-24 | 孙文洁 | Gynaecopathia external prescription and use in conjunction thereof |
| CN105994449A (en) * | 2016-07-21 | 2016-10-12 | 南通铁人体育设施工程有限公司 | Long-acting disinfectant for paper currency |
| CN108739873A (en) * | 2018-07-13 | 2018-11-06 | 李�杰 | A kind of auxiliary treatment tinea pedis uses insole cleaning solution |
| WO2021217324A1 (en) * | 2020-04-27 | 2021-11-04 | 陕西高源体外诊断试剂有限公司 | Disinfectant composition, preparation method therefor, and use thereof |
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2002
- 2002-04-24 CN CNB021114692A patent/CN1276714C/en not_active Expired - Fee Related
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