CN1274282A - 用噻唑烷二酮和α－葡糖苷酶抑制剂治疗糖尿病 - Google Patents

用噻唑烷二酮和α－葡糖苷酶抑制剂治疗糖尿病 Download PDF

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Publication number
CN1274282A
CN1274282A CN98806319A CN98806319A CN1274282A CN 1274282 A CN1274282 A CN 1274282A CN 98806319 A CN98806319 A CN 98806319A CN 98806319 A CN98806319 A CN 98806319A CN 1274282 A CN1274282 A CN 1274282A
Authority
CN
China
Prior art keywords
chemical compound
administration
alpha
glucosidase inhibitor
blood sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98806319A
Other languages
English (en)
Chinese (zh)
Inventor
S·A·史密斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9712865.6A external-priority patent/GB9712865D0/en
Priority claimed from GBGB9806708.5A external-priority patent/GB9806708D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of CN1274282A publication Critical patent/CN1274282A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
CN98806319A 1997-06-18 1998-06-15 用噻唑烷二酮和α－葡糖苷酶抑制剂治疗糖尿病 Pending CN1274282A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9712865.6 1997-06-18
GBGB9712865.6A GB9712865D0 (en) 1997-06-18 1997-06-18 Novel method of treatment
GBGB9806708.5A GB9806708D0 (en) 1998-03-27 1998-03-27 Novel method
GB9806708.5 1998-03-27

Publications (1)

Publication Number Publication Date
CN1274282A true CN1274282A (zh) 2000-11-22

Family

ID=26311746

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98806319A Pending CN1274282A (zh) 1997-06-18 1998-06-15 用噻唑烷二酮和α－葡糖苷酶抑制剂治疗糖尿病

Country Status (24)

Country Link
EP (1) EP0975343A1 (no)
JP (1) JP2001523271A (no)
KR (1) KR20010013845A (no)
CN (1) CN1274282A (no)
AP (1) AP9901720A0 (no)
AR (2) AR013352A1 (no)
AU (1) AU8799998A (no)
BG (1) BG103966A (no)
BR (1) BR9810186A (no)
CA (1) CA2294134A1 (no)
CO (1) CO4940453A1 (no)
DZ (1) DZ2519A1 (no)
EA (1) EA200000040A1 (no)
IL (1) IL133138A0 (no)
MA (1) MA26510A1 (no)
NO (1) NO996270L (no)
NZ (1) NZ501345A (no)
OA (1) OA11631A (no)
PE (1) PE89199A1 (no)
PL (1) PL337577A1 (no)
SK (1) SK179499A3 (no)
TR (1) TR199903072T2 (no)
UY (1) UY25051A1 (no)
WO (1) WO1998057635A1 (no)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101121004B (zh) * 2006-08-08 2010-07-21 鲁南制药集团股份有限公司 含有胰岛素增敏剂和米格列醇的药物组合物
CN101584705B (zh) * 2008-05-24 2010-10-27 鲁南制药集团股份有限公司 一种治疗糖尿病及其并发症的药物组合物
CN101584688B (zh) * 2008-05-24 2010-11-10 鲁南制药集团股份有限公司 一种治疗糖尿病及其并发症的药物组合物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000064892A2 (en) 1999-04-23 2000-11-02 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
CA2442917C (en) 2001-04-04 2011-02-01 Ortho-Mcneil Pharmaceutical, Inc. Combination therapy comprising glucose reabsorption inhibitors and ppar modulators
DE60233655D1 (de) 2001-04-04 2009-10-22 Ortho Mcneil Janssen Pharm R und retinoid x rezeptorenmodulatoren
FR2832930A1 (fr) * 2001-12-03 2003-06-06 Lipha Composition pharmaceutique comprenant un inhibiteur d'alpha-glucosidase et un derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete
JP2004067575A (ja) * 2002-08-06 2004-03-04 Yaizu Suisankagaku Industry Co Ltd 糖尿病治療薬効果促進剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0601001B1 (en) * 1991-08-26 1997-04-16 PHARMACIA & UPJOHN COMPANY Liquid food product containing 3-guanidinopropionic acid
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101121004B (zh) * 2006-08-08 2010-07-21 鲁南制药集团股份有限公司 含有胰岛素增敏剂和米格列醇的药物组合物
CN101584705B (zh) * 2008-05-24 2010-10-27 鲁南制药集团股份有限公司 一种治疗糖尿病及其并发症的药物组合物
CN101584688B (zh) * 2008-05-24 2010-11-10 鲁南制药集团股份有限公司 一种治疗糖尿病及其并发症的药物组合物

Also Published As

Publication number Publication date
EA200000040A1 (ru) 2000-08-28
JP2001523271A (ja) 2001-11-20
SK179499A3 (en) 2000-11-07
AR013352A1 (es) 2000-12-27
EP0975343A1 (en) 2000-02-02
PL337577A1 (en) 2000-08-28
CO4940453A1 (es) 2000-07-24
AR014881A1 (es) 2001-04-11
MA26510A1 (fr) 2004-12-20
NZ501345A (en) 2001-10-26
NO996270D0 (no) 1999-12-17
WO1998057635A1 (en) 1998-12-23
TR199903072T2 (xx) 2000-07-21
KR20010013845A (ko) 2001-02-26
BR9810186A (pt) 2000-08-08
AU8799998A (en) 1999-01-04
CA2294134A1 (en) 1998-12-23
AP9901720A0 (en) 1999-12-31
PE89199A1 (es) 1999-10-23
OA11631A (en) 2004-11-22
NO996270L (no) 1999-12-17
DZ2519A1 (fr) 2003-02-01
IL133138A0 (en) 2001-03-19
UY25051A1 (es) 2000-09-29
BG103966A (bg) 2000-07-31

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication