CN1272066C - Medicinal composition for relieving itching - Google Patents
Medicinal composition for relieving itching Download PDFInfo
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- CN1272066C CN1272066C CN 200410012128 CN200410012128A CN1272066C CN 1272066 C CN1272066 C CN 1272066C CN 200410012128 CN200410012128 CN 200410012128 CN 200410012128 A CN200410012128 A CN 200410012128A CN 1272066 C CN1272066 C CN 1272066C
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Abstract
The present invention discloses a medicinal composition for relieving itch, which comprises the raw materials of the following proportion by weight: 6 to 9 portions of swordlike atractylodes rhizome, 6 to 9 portions of rhizome, 6 to 9 portions of largetrifoliolious bugbane rhizome, 6 to 9 portions of radix puerariae, 4 to 12 portions of baical skullcap root, 4 to 12 portions of amur cork-tree, 6 to 9 portions of weeping forsythiae capsule, 3 to 9 portions of red peony root, 6 to 12 portions of ledebouriella root and 1 to 4 portions of fresh ginger. The medical composition has the advantages of favorable effect on relieving itch, short curing time, obvious long-time therapeutic effect, short therapeutic period and no adverse reaction through the toxicological tests of animals and clinical application.
Description
Affiliated field
The present invention relates to pharmaceutical product, specifically a kind of antipruritic agent compositions that is applicable to skin pruritus.
Technical background
Skin pruritus is the common skin disease.Its cause of disease complexity is with all multifactor relevant.Chinese medicine thinks that the cause of disease of this disease and damp and hot ailment said due to cold or exposure are strongly fragrant in skin, endogenous cause of ill with insufficiency of the spleen, the wet positive QI-insufficiency of spleen is relevant.It is extra-to be generally shape, and old complaint is in the lining.Clinical application at present is a lot, and as fluocinonide, dexamethasone, chlorphenamine, diphenhydramine, calcium gluconate or the like, but effect is all undesirable, and particularly late result has much room for improvement especially.
Summary of the invention
Purpose of the present invention just provides the good antipruritic agent compositions of a kind of antipruritic effect.
The object of the present invention is achieved like this:
Antipruritic agent compositions provided by the present invention includes the following weight proportion raw material:
6~9 parts of Rhizoma Atractylodis, 6~9 parts of the Rhizoma Atractylodis Macrocephalaes, 6~9 parts of Rhizoma Cimicifugaes, 6~9 parts of Radix Puerariaes, 4~12 parts of Radix Scutellariaes, 4~12 parts of Cortex Phellodendris, 6~9 parts of Fructus Forsythiaes, 3~9 parts of Radix Paeoniae Rubra, 6~12 parts of Radix Saposhnikoviaes, 1~4 part in Rhizoma Zingiberis Recens.
Each component of medicine of the present invention is determined through testing repeatedly, screening, and behind each component compatibility, has produced good synergism.
Among the present invention, the effect of playing yang invigorating altogether, detoxify, inducing sweat is share in Rhizoma Cimicifugae yang invigorating expelling pathogenic factors from the exterior, detoxifcation with Radix Puerariae.Radix Paeoniae Rubra removing pathogenic heat from blood and toxic substance from the body, regulating and activating blood circulation; The Rhizoma Atractylodis Macrocephalae is drying damp and strengthening spleen, the diuretic dampness removing; Radix Scutellariae, Fructus Forsythiae heat-clearing and toxic substances removing; Radix Saposhnikoviae drives the ailment said due to cold or exposure of human body, can send out ailment said due to cold or exposure and go out from the hair key, and Rhizoma Zingiberis Recens can be conciliate all medicines, helps ailment said due to cold or exposure to go out and the effect of conciliating taste is arranged.All medicines share, and have three clear effects, i.e. the poison of a clear fur; Damp and hot poison in the two clear bodies; Three stasis of blood poison in purifying the blood.
Pharmaceutical composition of the present invention is monarch drug with the antipyretic, is ministerial drug with the invigorating spleen to remove dampness medicine, and the wet spleen that goes is strong, and it is adjuvant drug that wind dispelling is searched the network medicine, thereby reaches the purpose for the treatment of both the principal and secondary aspects of a disease.Because of its periphery of itching is wind, cold is arranged in the wind again, so separate in the wind cold with a small amount of guiding drug.
Compatibility of the present invention is precise and appropriate, drug effect obvious, the focus of can going directly, and has the effect of getting instant result.
For strengthening the effect of detoxifcation of the present invention, can in compositions, increase the following weight proportion raw material: 10~12 parts of Flos Loniceraes.
For further strengthening the effect of its dampness removing heat clearing away, can in compositions, increase the following weight proportion raw material: 30~45 parts of Rhizoma Smilacis Glabraes, 6~9 parts of Radix Sophorae Flavescentiss.
Also can in compositions, increase the following weight proportion raw material: 6~9 parts of Radix Angelicae Sinensis, 20~30 parts of the Fructus Kochiae, 6~9 parts of Periostracum Cicadaes.With further enhancing drug effect of the present invention.
Pharmaceutical composition of the present invention can be prepared into capsule, honeyed pill, decoction, oral liquid, also can be prepared into lotion and liniment.
The preparation method of medicament composition capsule of the present invention is:
After each medicine components oven dry of the present invention, take by weighing, sterilize, pulverized 80 mesh sieves by its weight proportion, mixing, in incapsulating, every capsules nearly weighs 0.5 gram.
Other dosage forms of pharmaceutical composition of the present invention all can be prepared by the conventional preparation method in the pharmaceutics.
Pharmaceutical composition of the present invention has that heat-clearing and toxic substances removing, removing heat from blood nourish blood, dampness removing blood stasis dispelling, the antipruritic effect of wind dispelling.
Can be used for treating acute and chronic urticaria, acute and chronic eczema, recurrent eczema, intractable eczema, acute and chronic dermatitis, vulva pruritus, skin itching diseases such as eczema scrotum.
Instructions of taking of the present invention is:
Capsule is taken 4~6 at every turn, every day three times.
Decoction every day three times, take at every turn and be equivalent to crude drug in whole 6~9 grams.
The other drug of can stopping using during the treatment, and can keep original diet and living habit constant.Acute stage,, chronic patients was to take capsule based on decoction or oral liquid.Be seven days a course of treatment, and the general lighter patient of symptom takes a course of treatment and can fully recover, and sick time is grown (more than half a year) and then need be taken 2~4 courses of treatment.
Pharmaceutical composition of the present invention has good antipruritic effect, and its healing time is short, and late result is definite, short treating period, and do not find untoward reaction through animal toxicology test and clinical practice.
Beneficial effect of the present invention is confirmed by following experiment.
Physical data
100 routine skin pruritus patients (age is at 8 years old~60 years old, and year does not wait disease time a few days~10, and the male patient accounts for 42%, and female patient accounts for 58%).All case is a primary symptom with part or whole skin pruritus all, with the red pimple of skin, welt or scratch.Wherein have 52% patient to use chlorphenamine, dexamethasone, calcium gluconate, but all effect is bad or have a relapse.
Therapeutic Method:
The patient of disease time within a few days takes course of treatment of capsule of the present invention (clean skin itching-relieving capsule, the i.e. made capsule of embodiment 1).Disease time is taken 2~4 courses of treatment of capsule of the present invention the patient more than ten days.
Curative effect judging standard:
Recovery from illness: no pruritus; Produce effects: pruritus once in a while, not medication do not influence the work and study life; Invalid: pruritus does not alleviate, and influences work and study.
Therapeutic outcome, recovery from illness accounts for 88%, produce effects 10%, total effective rate 98%, invalid 2%.
In the recovery from illness patient, 33 patients that come to go to a doctor because of having a relapse are arranged.This test has been carried out following up a case by regular visits in 5 years to the patient after fully recovering, and does not see recidivist again.
The specific embodiment
Embodiment 1
Take by weighing Rhizoma Atractylodis 6kg, Rhizoma Atractylodis Macrocephalae 6kg, Rhizoma Cimicifugae 9kg, Radix Puerariae 9kg, Radix Scutellariae 6kg, Cortex Phellodendri 6kg, Fructus Forsythiae 9kg, Radix Paeoniae Rubra 4.5kg, Radix Saposhnikoviae 9kg, Rhizoma Zingiberis Recens 1.5kg.
With above all medicines, oven dry, dry sterilization was pulverized 80 mesh sieves, and mix homogeneously incapsulates.Every capsules weighs 0.5 gram.
Following examples 2~5, its preparation method are with embodiment 1, and just component and proportioning weight are different, but all can realize effect of the present invention.
Claims (4)
1, a kind of antipruritic agent compositions is characterized in that it includes the following weight proportion raw material:
6~9 parts of Rhizoma Atractylodis, 6~9 parts of the Rhizoma Atractylodis Macrocephalaes, 6~9 parts of Rhizoma Cimicifugaes, 6~9 parts of Radix Puerariaes, 4~12 parts of Radix Scutellariaes, 4~12 parts of Cortex Phellodendris, 6~9 parts of Fructus Forsythiaes, 3~9 parts of Radix Paeoniae Rubra, 6~12 parts of Radix Saposhnikoviaes, 1~4 part in Rhizoma Zingiberis Recens.
2, antipruritic agent compositions according to claim 1 is characterized in that it also has the following weight proportion raw material: 10~12 parts of Flos Loniceraes.
3, antipruritic agent compositions according to claim 1 is characterized in that it also includes the following weight proportion raw material: 30~45 parts of Rhizoma Smilacis Glabraes, 6~9 parts of Radix Sophorae Flavescentiss.
4, antipruritic agent compositions according to claim 3 is characterized in that it also has the following weight proportion raw material: 6~9 parts of Radix Angelicae Sinensis, 20~30 parts of the Fructus Kochiae, 6~9 parts of Periostracum Cicadaes.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200410012128 CN1272066C (en) | 2004-01-18 | 2004-01-18 | Medicinal composition for relieving itching |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200410012128 CN1272066C (en) | 2004-01-18 | 2004-01-18 | Medicinal composition for relieving itching |
Publications (2)
Publication Number | Publication Date |
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CN1640451A CN1640451A (en) | 2005-07-20 |
CN1272066C true CN1272066C (en) | 2006-08-30 |
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Application Number | Title | Priority Date | Filing Date |
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CN 200410012128 Expired - Fee Related CN1272066C (en) | 2004-01-18 | 2004-01-18 | Medicinal composition for relieving itching |
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Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101491575B (en) * | 2008-12-18 | 2012-04-25 | 浙江省中医院 | Traditional Chinese medicine extract for treating atopic dermatitis and granules thereof |
CN102488851B (en) * | 2011-12-28 | 2013-08-21 | 张志远 | Drug for treating recurrent genital herpes and preparation method thereof |
CN102973674B (en) * | 2012-11-22 | 2014-08-13 | 张继成 | Eczema eliminating capsule |
CN103202979A (en) * | 2013-03-04 | 2013-07-17 | 余金标 | Powder for treatment of scrotal eczema by using cascara Sagrada |
CN103784588B (en) * | 2014-01-22 | 2016-09-28 | 陈天丽 | A kind of Chinese drugs agentia treating seborrheic dermatitis and preparation method |
CN104208535A (en) * | 2014-09-29 | 2014-12-17 | 张晨 | Externally applied ointment for treating eczema |
CN104857419A (en) * | 2015-05-18 | 2015-08-26 | 黄克会 | Medicine for treating pruritus inside and outside private parts of men and women |
CN105267799A (en) * | 2015-11-16 | 2016-01-27 | 吴斌 | Medicine for treating chronic eczema |
CN105770655A (en) * | 2016-04-24 | 2016-07-20 | 邹洪胜 | Traditional Chinese medicine composition for treating scroti eczema |
CN105878811A (en) * | 2016-06-17 | 2016-08-24 | 杜威 | External-use traditional Chinese medicine for treating rubella itching |
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2004
- 2004-01-18 CN CN 200410012128 patent/CN1272066C/en not_active Expired - Fee Related
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CN1640451A (en) | 2005-07-20 |
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