CN1225254C - Medicinal composition, its preparation process and use in treating psoriasis - Google Patents
Medicinal composition, its preparation process and use in treating psoriasis Download PDFInfo
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- CN1225254C CN1225254C CN 02110385 CN02110385A CN1225254C CN 1225254 C CN1225254 C CN 1225254C CN 02110385 CN02110385 CN 02110385 CN 02110385 A CN02110385 A CN 02110385A CN 1225254 C CN1225254 C CN 1225254C
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Abstract
The present invention belongs to a medicinal composition with curative activity and relates to a medicinal composition, a preparation method and the application in medicines for treating psoriasis thereof. The medicinal composition is prepared from medicinal materials as the main medicines according to the following weights: 25 to 35 portions of coptis or dandelion, 25 to 35 portions of garlic or baical skullcap root, 25 to 35 portions of yellow-corktree bark or purslane herb, 25 to 35 portions of great burdock achene or kuhseng, 25 to 35 portions of hemlock parsley or red sage root, 25 to 35 portions of olibanum or myrrh, 25 to 35 portions of salicylic acid or golden larch bark, 90 to 110 portions of natural indigo or dictamni cortex and 40 to 60 portions of realgar or sulphur. The medicines are respectively pulverized and are sieved by 100 to 200 meshes of screens; the medicines are added to a hydrophilic oleaginous base, a water containing oleaginous base or an oleaginous base with ordinary amount to be uniformly mixed. Thereby, an external ointment is manufactured. The present invention has the advantages that the combination principle is based on clearing away heat and toxic material, promoting blood circulation and alleviating itch; the medicinal composition has no toxin or stimulation and has stable therapeutic effect. The medicinal composition develops a new method, namely that the medicinal composition uses large dose of medicines for clearing away heat and toxic material as the main components and a proper amount of medicines for promoting blood circulation and alleviating itch is taken as the auxiliary medicines. Therefore, the medicinal composition has no hormone absolutely.
Description
Technical field
The invention belongs to Pharmaceutical composition category, relate in particular to the psoriatic externally-applied soft ointment of a kind of treatment with therapeutic activity.
Background technology
Psoriasis is a kind of chronic inflammatory disease dermatoses, and its erythra shows as red macule, pimple or speckle, and surface coverage the silvery white squama of multilamellar.The cause of disease is not made clear so far as yet fully, may be relevant with heredity, immunologic function disorder, infection and dysbolismus.Usually doctor trained in Western medicine is taken stopgap measures, antipruritic, antiinflammatory, and based on hormonotherapy, drawback is a lot of.
The traditional Chinese medical science is thought, psoriatic formation, to belong to noxious heat in the blood system flourishing more, the nutrient blood loss, give birth to dry humorously, due to the failure of skin and muscle to be nourished.The generation of its heat in blood is that multiple factor causes, as internal injury caused by excess of seven emotions, and obstruction of QI, strongly fragrant fire-transformation of a specified duration is so that hyperactivity of heart-fire.Heart governing blood and vessels, hyperactivity of heart-fire be the nutrient blood of heat volt then; Or improper diet, have a liking for tobacco and wine and pungent thing, the product of delicious food wind symptom usually, so that insufficiency of the spleen leading to overabundance of dampness, strongly fragrant heat-transformation of a specified duration, flesh heat is worked as wind in addition, is subjected to the heresy invasion and attack of six climate exopathogens outward, and interior foreign minister fights and falls ill.Though the traditional Chinese medical science cures mainly this, right oral drugs need to absorb conversion through digestive tract, and are slow and faint when passing on disease institute.
2001,10, the 03 disclosed patent No. be ZL00110973.1's " treating psoriatic ointment ", adopt the skin dispenser, curative effect improves; Yet principle of medication has been used for example hypertoxic medicine of Calomelas and so on based on antibacterial counteracting toxic substances, and still be unable to do without hormone (dexamethasone) in the prescription and cutaneous permeable agent (dimethyl sulfoxide) has zest.
Summary of the invention
Purpose of the present invention is to overcome above-mentioned defective, and according to heat-clearing and toxic substances removing, the antipruritic principle of invigorating blood circulation is selected no hormone, nontoxic pharmaceutical composition compatibility for use.
Technical scheme of the present invention is: develop the psoriatic Pharmaceutical composition of a kind of treatment, it is characterized in that the externally-applied soft ointment made from the medical material of following weight:
40～60 parts of 25～35 parts of Rhizoma Coptidis or Herba Taraxacis, Bulbus Allii or 25～35 parts of Radix Scutellariaes, Cortex Phellodendri or 25～35 parts of Herba Portulacaes, Fructus Arctii or 25～35 parts of Radix Sophorae Flavescentiss, Rhizoma Chuanxiong or 25～35 parts of Radix Salviae Miltiorrhizaes, Olibanum or 25～35 parts of Myrrhas, salicylic acid or 25～35 parts of Cortex Pseudolaricis, Indigo Naturalis or 90～110 parts of Cortex Dictamnis and Realgar or sulfurs.
The preparation method of the psoriatic Pharmaceutical composition of above-mentioned treatment, with Rhizoma Coptidis or Herba Taraxaci, Bulbus Allii or Radix Scutellariae, Cortex Phellodendri or Herba Portulacae, Fructus Arctii or Radix Sophorae Flavescentis, Rhizoma Chuanxiong or Radix Salviae Miltiorrhizae, Olibanum or Myrrha, salicylic acid or Cortex Pseudolaricis, Indigo Naturalis or Cortex Dictamni and Realgar or sulfur, pulverize separately becomes fine powder, cross 100～200 mesh sieves, be incorporated in the hydrophilic of convention amount, the moisture oil or greasing base, stir evenly, make externally-applied soft ointment, packing gets final product.
The application of the psoriatic Pharmaceutical composition of above-mentioned treatment in preparation treatment psoriasis medicine.
On probation through the court's outpatient service, treat hundreds of person-times, make the psoriasis herb medicinal paste for external application, total effective rate 95.38%; Clinical cure rate 85.66%; Obvious effective rate 9.72%; Inefficiency 4.62%.
Advantage of the present invention is:
1. the principle of drug regimen is a heat-clearing and toxic substances removing, and it is antipruritic to invigorate blood circulation, nontoxic, non-stimulated, and stable curative effect;
2. look for another way, it is main adopting heavy dose of heat-clearing and toxic substances removing medicine, be aided with in right amount invigorate blood circulation, sterilization, antipruritic agent; Contain hormone anything but, do not have hypertoxic medicine.
The specific embodiment
Embodiment 1
40 parts of 25 parts of Rhizoma Coptidis, 35 parts in Bulbus Allii, 25 parts of Cortex Phellodendris, 35 parts of Radix Sophorae Flavescentiss, 25 parts of Rhizoma Chuanxiongs, 35 parts of Olibanums, 25 parts of salicylic acid, 110 parts of Cortex Dictamnis and Realgars.More than all medicines be ground into fine powder after the purified treatment respectively, cross 200 mesh sieves, be incorporated in the hydrophilic ointment substrate that sorbitol, 1, ammediol, polyoxyethylene glycol class and ethyl nipalgin substrate makes and stir evenly, make externally-applied soft ointment, packing.42～50 ℃ of softening points are made the psoriasis herb medicinal paste for external application.
Embodiment 2
60 parts of 35 parts of Herba Taraxacis, 25 parts of Radix Scutellariaes, 35 parts of Herba Portulacaes, 25 parts of Fructus Arctiis, 35 parts of Radix Salviae Miltiorrhizaes, 25 parts of Myrrhas, 35 parts of Cortex Pseudolaricis, 90 parts of Indigo Naturaliss and sulfurs.Cross 100 mesh sieves, be incorporated in the moisture greasing base of sodium lauryl sulfate, Cetyl Alcohol, vaseline, liquid paraffin, water, propylene glycol and methyl Ni Bo composition, surplus with example 1.
Embodiment 3
50 parts of 30 parts of Rhizoma Coptidis, 30 parts in Bulbus Allii, 30 parts of Cortex Phellodendris, 30 parts of Radix Sophorae Flavescentiss, 305 parts of Rhizoma Chuanxiongs, 30 parts of Myrrhas, 30 parts of Cortex Pseudolaricis, 100 parts of Indigo Naturaliss and Realgars.Cross 120 mesh sieves, be incorporated in the greasing base of sodium lauryl sulfate, Cetyl Alcohol, vaseline, liquid paraffin and propylene glycol composition, surplus with example 1.
Embodiment 4
50 parts of 28 parts of Rhizoma Coptidis, 28 parts of Radix Scutellariaes, 285 parts of Cortex Phellodendris, 28 parts of Radix Sophorae Flavescentiss, 28 parts of Radix Salviae Miltiorrhizaes, 28 parts of Olibanums, 28 parts of salicylic acid, 100 parts of Indigo Naturaliss and sulfurs.Cross 120 mesh sieves, be incorporated in the hydrophilic ointment substrate of sorbitol, glycerol, polyoxyethylene glycol-400 and propyl group Ni Bo composition, surplus with example 1.
Embodiment 5
55 parts of 32 parts of Herba Taraxacis, 30 parts of Radix Scutellariaes, 28 parts of Herba Portulacaes, 30 parts of Radix Sophorae Flavescentiss, 28 parts of Rhizoma Chuanxiongs, 32 parts of Olibanums, 30 parts of salicylic acid, 105 parts of Indigo Naturaliss and sulfurs.Cross 100 mesh sieves, be incorporated in the moisture greasing base of sodium lauryl sulfate, Cetyl Alcohol, vaseline, liquid paraffin, water, propylene glycol and methyl Ni Bo composition, surplus with example 1.
Embodiment 6
40 parts of 305 parts of Rhizoma Coptidis, 28 parts of Radix Scutellariaes, 30 parts of Cortex Phellodendris, 32 parts of Radix Sophorae Flavescentiss, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts of Olibanums, 30 parts of salicylic acid, 110 parts of Indigo Naturaliss and Realgars.Cross 120 mesh sieves, be incorporated in the greasing base of sodium lauryl sulfate, Cetyl Alcohol, lanoline, vaseline, liquid paraffin and propylene glycol composition, surplus with example 1.
Embodiment 7
50 parts of 30 parts of Rhizoma Coptidis, 28 parts in Bulbus Allii, 32 parts of Cortex Phellodendris, 32 parts of Fructus Arctiis, 30 parts of Rhizoma Chuanxiongs, 35 parts of Olibanums, 35 parts of Cortex Pseudolaricis, 95 parts of Cortex Dictamnis and Realgars.Cross 100 mesh sieves, be incorporated in the moisture greasing base of sodium lauryl sulfate, Cetyl Alcohol, vaseline, liquid paraffin, water, propylene glycol and methyl Ni Bo composition, surplus with example 1.
Embodiment 8
60 parts of 35 parts of Rhizoma Coptidis, 35 parts of Radix Scutellariaes, 30 parts of Cortex Phellodendris, 28 parts of Radix Sophorae Flavescentiss, 28 parts of Radix Salviae Miltiorrhizaes, 35 parts of Olibanums, salicylic acid～35 part, 110 parts of Indigo Naturaliss and sulfurs.Cross 120 mesh sieves, be incorporated in the greasing base of sodium lauryl sulfate, Cetyl Alcohol, vaseline, liquid paraffin and propylene glycol composition, surplus with example 1.
Embodiment 9
60 parts of 35 parts of Herba Taraxacis, 25 parts in Bulbus Allii, 35 parts of Herba Portulacaes, 35 parts of Fructus Arctiis, 35 parts of Rhizoma Chuanxiongs, 25 parts of Myrrhas, 35 parts of Cortex Pseudolaricis, 100 parts of Indigo Naturaliss and sulfurs.Cross 120 mesh sieves, be incorporated in the hydrophilic ointment substrate of sorbitol, glycerol, polyoxyethylene glycol-400 and propyl group Ni Bo composition, surplus with example 1.
60 parts of 32 parts of embodiment 10 Rhizoma Coptidis, 35 parts in Bulbus Allii, 25 parts of Cortex Phellodendris, 35 parts of Radix Sophorae Flavescentiss, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts of Olibanums, 35 parts of Cortex Pseudolaricis, 110 parts of Indigo Naturaliss and Realgars.Cross 120 mesh sieves, be incorporated in the greasing base of sodium lauryl sulfate, Cetyl Alcohol, lanoline, vaseline, liquid paraffin and propylene glycol composition, surplus with example 1.
Claims (3)
1. treat psoriatic Pharmaceutical composition for one kind, it is characterized in that the externally-applied soft ointment made from the medical material of following weight:
40～60 parts of 25～35 parts of Rhizoma Coptidis or Herba Taraxacis, Bulbus Allii or 25～35 parts of Radix Scutellariaes, Cortex Phellodendri or 25～35 parts of Herba Portulacaes, Fructus Arctii or 25～35 parts of Radix Sophorae Flavescentiss, Rhizoma Chuanxiong or 25～35 parts of Radix Salviae Miltiorrhizaes, Olibanum or 25～35 parts of Myrrhas, salicylic acid or 25～35 parts of Cortex Pseudolaricis, Indigo Naturalis or 90～110 parts of Cortex Dictamnis and Realgar or sulfurs.
2. according to the preparation method of the psoriatic Pharmaceutical composition of the described treatment of claim 1, it is characterized in that Rhizoma Coptidis or Herba Taraxaci, Bulbus Allii or Radix Scutellariae, Cortex Phellodendri or Herba Portulacae, Fructus Arctii or Radix Sophorae Flavescentis, Rhizoma Chuanxiong or Radix Salviae Miltiorrhizae, Olibanum or Myrrha, salicylic acid or Cortex Pseudolaricis, Indigo Naturalis or Cortex Dictamni and Realgar or sulfur, pulverize separately becomes fine powder, cross 100～200 mesh sieves, be incorporated in the hydrophilic of convention amount, the moisture oil or greasing base, stir evenly, make externally-applied soft ointment, packing gets final product.
3. according to the application of the psoriatic Pharmaceutical composition of the described treatment of claim 1 in preparation treatment psoriasis medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02110385 CN1225254C (en) | 2002-05-09 | 2002-05-09 | Medicinal composition, its preparation process and use in treating psoriasis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02110385 CN1225254C (en) | 2002-05-09 | 2002-05-09 | Medicinal composition, its preparation process and use in treating psoriasis |
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| Publication Number | Publication Date |
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| CN1385187A CN1385187A (en) | 2002-12-18 |
| CN1225254C true CN1225254C (en) | 2005-11-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 02110385 Expired - Fee Related CN1225254C (en) | 2002-05-09 | 2002-05-09 | Medicinal composition, its preparation process and use in treating psoriasis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100551394C (en) * | 2007-01-19 | 2009-10-21 | 马学荣 | Medicine for treating psoriasis |
| CN102755502A (en) * | 2012-08-06 | 2012-10-31 | 廖丽萍 | External use washing liquor for relieving psoriasis |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005094861A1 (en) * | 2004-04-02 | 2005-10-13 | Sung-Bae Park | Composition for treating psoriasis-associated diseases |
| CN100350930C (en) * | 2005-11-22 | 2007-11-28 | 张�浩 | External-application Chinese medicine for treating psoriasis |
| CN100394956C (en) * | 2006-05-31 | 2008-06-18 | 高文勇 | Externally-applied medicinef or treating psoriasis |
| CN102579976A (en) * | 2012-02-27 | 2012-07-18 | 汪世龙 | External medicine for treating psoriasis |
| CN107569593A (en) * | 2017-08-30 | 2018-01-12 | 云南宏绿辣素有限公司 | One kind treats psoriasic ointment and preparation method thereof |
| CN115105550B (en) * | 2022-08-02 | 2023-06-13 | 新疆医科大学第四附属医院 | Traditional Chinese medicine composition for treating psoriasis and lotion |
-
2002
- 2002-05-09 CN CN 02110385 patent/CN1225254C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100551394C (en) * | 2007-01-19 | 2009-10-21 | 马学荣 | Medicine for treating psoriasis |
| CN102755502A (en) * | 2012-08-06 | 2012-10-31 | 廖丽萍 | External use washing liquor for relieving psoriasis |
| CN102755502B (en) * | 2012-08-06 | 2013-12-25 | 廖丽萍 | External use washing liquor for relieving psoriasis |
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| Publication number | Publication date |
|---|---|
| CN1385187A (en) | 2002-12-18 |
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