CN1266156C - 抗乙肝病毒药物阿德福韦酯的合成方法 - Google Patents
抗乙肝病毒药物阿德福韦酯的合成方法 Download PDFInfo
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- CN1266156C CN1266156C CN 200410015562 CN200410015562A CN1266156C CN 1266156 C CN1266156 C CN 1266156C CN 200410015562 CN200410015562 CN 200410015562 CN 200410015562 A CN200410015562 A CN 200410015562A CN 1266156 C CN1266156 C CN 1266156C
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- phosphonium mesitoyl
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CN 200410015562 CN1266156C (zh) | 2004-03-05 | 2004-03-05 | 抗乙肝病毒药物阿德福韦酯的合成方法 |
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CN 200410015562 CN1266156C (zh) | 2004-03-05 | 2004-03-05 | 抗乙肝病毒药物阿德福韦酯的合成方法 |
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CN1560059A CN1560059A (zh) | 2005-01-05 |
CN1266156C true CN1266156C (zh) | 2006-07-26 |
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CN 200410015562 Expired - Fee Related CN1266156C (zh) | 2004-03-05 | 2004-03-05 | 抗乙肝病毒药物阿德福韦酯的合成方法 |
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Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100395248C (zh) * | 2006-05-26 | 2008-06-18 | 华东理工大学 | 一种9-(二乙氧基磷酰基甲氧基乙基)-腺嘌啉的制备方法 |
CN101085785B (zh) * | 2006-06-06 | 2011-09-21 | 中国科学院上海药物研究所 | 用于治疗乙型肝炎的嘌呤类化合物及其制备方法和用途,以及包括该化合物的组合物 |
CN101450954B (zh) * | 2007-12-05 | 2013-05-08 | 中国人民解放军第二军医大学 | 核苷酸类似物及其应用,以及含该核苷酸类似物的药物组合物 |
CN101817847B (zh) * | 2009-02-26 | 2012-05-23 | 湖南欧亚生物有限公司 | 一种生产阿德福韦的方法 |
CN101830932B (zh) * | 2009-02-26 | 2012-11-21 | 湖南欧亚生物有限公司 | 一种阿德福韦酯原料药的合成工艺 |
CN101891767B (zh) * | 2010-07-21 | 2012-05-23 | 浙江贝得药业有限公司 | 一种阿德福韦酯的制备方法 |
CN102120748B (zh) * | 2011-01-18 | 2014-01-08 | 浙江山峪染料化工有限公司 | 高纯度9-(2-二乙氧基膦酰甲氧乙基)腺嘌呤的制备方法 |
CN102250146A (zh) * | 2011-05-27 | 2011-11-23 | 扬州三友合成化工有限公司 | 抗乙肝药物阿德福韦的一种合成方法 |
CN106317115A (zh) * | 2015-06-29 | 2017-01-11 | 天津市亨必达化学合成物有限公司 | 一种阿德福韦的制备方法 |
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Owner name: GUANGDONG JING HAO PHARMACEUTICAL TECHNOLOGY DEVE Free format text: FORMER OWNER: HU XIAOXIA Effective date: 20050715 |
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Owner name: ZHEJIANG FUWEI PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: GUANGDONG JINGHAO MEDICAL TECHNOLOGY DEVELOPMENT CO., LTD. Effective date: 20110328 |
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