CN1263770A - Thrombolytic medicine and its preparing process - Google Patents
Thrombolytic medicine and its preparing process Download PDFInfo
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- CN1263770A CN1263770A CN 99122641 CN99122641A CN1263770A CN 1263770 A CN1263770 A CN 1263770A CN 99122641 CN99122641 CN 99122641 CN 99122641 A CN99122641 A CN 99122641A CN 1263770 A CN1263770 A CN 1263770A
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Abstract
A thrombolytic medicine able to prevent the action of thrombase to fibrinogen and to treat cerebral apoplexy is prepared from astragalus root, red sage root, Chuan-xiong rhizome, leech and baked Semen strychni through honeying to obtain pills.
Description
The present invention relates to a kind of deriving from the plant is the technical field of medicine of material, particularly a kind of thrombolytic medicine and preparation method thereof.
At present, the research of apoplexy is the problem that medical profession is paid close attention to most with treatment.The acute stage of apoplexy, generally carried out thrombolytic in morbidity in 6 hours, but many patients have surpassed the thrombolytic time when coming institute to go to a doctor, if adopt other Therapeutic Method effect often not good.On the other hand, the medicine thrombolytic first-selection that adopts be urokinase, but the easiest the causing bleeding of side effect of urokinase also has and adopts multiple Serpentis Ahylysantinfarctase treatment, but want the running check platelet and time of blood coagulation occurs, change, occur clotting time as platelet and shorten and then will discontinue medication.According to the practical situation of present existence, the characteristics and the pathological change of apoplexy morbidity adopt the Chinese medicine thrombolytic medicine to treat the acute stage of apoplexy, and it is very satisfied that curative effect is made us.
The objective of the invention is deficiency at said medicine, pharmacological action in line with Chinese herbal medicine, and provide a kind of thrombolytic medicine and preparation method thereof, stop thrombin to the fibronectin effect, and the excited spinal reflex function of energy, improve the suffering from acute stroke disturbance of cerebral circulation, make the abnormal blood flow state change into state of normal blood flow, blood viscosity lowering prevents the formation again of microthrombus.
Thrombolytic medicine of the present invention and preparation method thereof description is as follows.
A kind of thrombolytic medicine is characterized in that: it is the medicament of being made by the following weight proportion raw material substantially:
Radix Astragali 10-50 part, Radix Salviae Miltiorrhizae 5-20 part, Rhizoma Chuanxiong 5-20 part, Hirudo 1-10 part, Semen Strychni (processed) 0.1-1 part.
1: 1.1 (weight ratio, as follows) of honey during the total weight parts that above-mentioned medical material is made powder adds, closing sticks together makes pill.
Adopt traditional method of Chinese medicinal, that said medicine can also be made is diffusing, cream, pellet, capsule formulation.
Manufacturing method for above mentioned medicine is characterized in that:
Above-mentioned medical material is clean through screening, remove impurity, adopt the infrared drying oven oven dry, temperature is cut into fragment less than 100 ℃ with medicine cutter, the reuse pulverizer becomes medicated powder with the fragment powder, medicated powder is crossed 100 mesh sieves, gets its minus sieve material, and honey closes stick together and makes honeyed pill at 1: 1.1 in adding.
Characteristics of the present invention are to have replenished a kind of apoplexy acute stage medication on the medical market.And overcome the side effect that apoplexy acute stage use urokinase causes bleeding, also overcome and adopted multiple Serpentis Ahylysantinfarctase to produce the side effect of blood coagulation.At apoplexy acute stage blood change, can stop thrombin to the fibronectin effect, and the reflection function of the excited spinal cord of energy, improve the suffering from acute stroke disturbance of cerebral circulation, make the abnormal blood flow state change into state of normal blood flow, blood viscosity lowering, prevent that microthrombus from forming again, thereby improved cerebrovascular elastic force, brain cell is recovered, reduce neural damage, improved the limb function and the aphasis of paralysis.To the acute stage of apoplexy, symptom curative effects such as hemiplegia, dysphonia, distortion of commissure are very satisfied suddenly, and nontoxic pair of effect.
Embodiment 1
Get 10 parts of raw medicinal material (weight portion) Radixs Astragali, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Rhizoma Chuanxiongs, 1 part of Hirudo, 0.1 part of Semen Strychni (processed).
Manufacturing method for above mentioned medicine is, and is medical material is clean through screening, remove impurity, adopt the infrared drying oven oven dry, and temperature is less than 100 ℃, be cut into fragment with medicine cutter, the reuse pulverizer becomes medicated powder with the fragment powder, and medicated powder is crossed 100 mesh sieves, get its minus sieve material, honey closes stick together and makes honeyed pill at 1: 1.1 in adding.
Embodiment 2
Get 30 parts of raw medicinal material (weight portion) Radixs Astragali, 12.5 parts of Radix Salviae Miltiorrhizaes, 12.5 parts of Rhizoma Chuanxiongs, 5.5 parts of Hirudos, 0.5 part of Semen Strychni (processed).All the other are with embodiment 1.
Embodiment 3
Get 50 parts of raw medicinal material (weight portion) Radixs Astragali, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Rhizoma Chuanxiongs, 10 parts of Hirudos, 1 part of Semen Strychni (processed).All the other are with embodiment 1.
Embodiment 4
Adopt the raw medicinal material of embodiment 1,2 or 3, adopt traditional method of Chinese medicinal, can make powder.
Embodiment 4
Adopt the raw medicinal material of embodiment 1,2 or 3, adopt traditional method of Chinese medicinal, can make powder.
Embodiment 5
Adopt the raw medicinal material of embodiment 1,2 or 3, adopt traditional method of Chinese medicinal, can make sublimed preparation.
Embodiment 6
Adopt the raw medicinal material of embodiment 1,2 or 3, adopt traditional method of Chinese medicinal, can make capsule formulation.
Embodiment 7
Adopt the raw medicinal material of embodiment 1,2 or 3, adopt traditional method of Chinese medicinal, can make unguentum.
Claims (4)
1. thrombolytic medicine is characterized in that: it is the medicament of being made by the following weight proportion raw material substantially:
Radix Astragali 10-50 part, Radix Salviae Miltiorrhizae 5-20 part, Rhizoma Chuanxiong 5-20 part, Hirudo 1-10 part, Semen Strychni (processed) 0.1-1 part.
2. a kind of thrombolytic medicine as claimed in claim 1 is characterized in that: honey was 1: 1.1 during the total weight parts that above-mentioned medical material is made powder added, and closing sticks together makes pill.
3. a kind of thrombolytic medicine as claimed in claim 1 is characterized in that: can also make diffusing, cream, pellet, capsule formulation.
4. manufacturing method for above mentioned medicine is characterized in that:
Above-mentioned medical material is clean through screening, remove impurity, adopt the infrared drying oven oven dry, temperature is cut into fragment less than 100 ℃ with medicine cutter, the reuse pulverizer becomes medicated powder with the fragment powder, medicated powder is crossed 100 mesh sieves, gets its minus sieve material, and honey closes stick together and makes honeyed pill at 1: 1.1 in adding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99122641A CN1101220C (en) | 1999-12-17 | 1999-12-17 | Thrombolytic medicine and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99122641A CN1101220C (en) | 1999-12-17 | 1999-12-17 | Thrombolytic medicine and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1263770A true CN1263770A (en) | 2000-08-23 |
| CN1101220C CN1101220C (en) | 2003-02-12 |
Family
ID=5282628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99122641A Expired - Fee Related CN1101220C (en) | 1999-12-17 | 1999-12-17 | Thrombolytic medicine and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1101220C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100339092C (en) * | 2005-07-21 | 2007-09-26 | 南京蓝本科技有限公司 | Chinese medicine composition for treating apoplexy and its prepn process and use |
-
1999
- 1999-12-17 CN CN99122641A patent/CN1101220C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100339092C (en) * | 2005-07-21 | 2007-09-26 | 南京蓝本科技有限公司 | Chinese medicine composition for treating apoplexy and its prepn process and use |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1101220C (en) | 2003-02-12 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |