CN1259946C - Chinese traditional medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension - Google Patents

Chinese traditional medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension Download PDF

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CN1259946C
CN1259946C CN 200410082747 CN200410082747A CN1259946C CN 1259946 C CN1259946 C CN 1259946C CN 200410082747 CN200410082747 CN 200410082747 CN 200410082747 A CN200410082747 A CN 200410082747A CN 1259946 C CN1259946 C CN 1259946C
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cerebral edema
intracranial hypertension
medicine composition
hydrocephalus
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CN1634385A (en
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谢静
贾文发
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Abstract

The present invention relates to a Chinese medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension, which is composed of 10 to 30g of otolithum sciaenae, 15 to 100 g of raw milkvetch root, 5 to 25 g of raw rhizoma alismatis, 10 to 50g of tuckahoe, 10 to 30g of plantain seed, 10 to 40g of notoginseng, 10 to 100g of red sage root, 10 to 30g of fructus liquidambaris, 10 to 30g of grassleaf sweetflag rhizome, 5 to 25g of medicinal evodia fruit, 10 to 50g of achyranthes. The present invention has the advantages of obvious diuretic effect, little side effect, obvious effect on anticonvulsant, sedation, spasmolysis and analgesia, and has the functions of benefiting qi for activating blood circulation, dredging collaterals for diuresis, improving cerebrum microcirculatory, promoting attraction of cerebrospinal fluid, resisting inflammation, eliminating swelling, softening adhesion, relieving obstruction of cerebrospinal fluid circulation, protecting and restoring neurocyte function; besides, the present invention can treat hydrocephalus, cerebral edema and intracranial hypertension syndromes caused by various reasons with conspicuous curative effects, short course of treatment and obvious effects.

Description

The Chinese medicine composition of treatment hydrocephalus, cerebral edema and intracranial hypertension
Technical field
The invention belongs to a kind of Chinese medicine preparation, particularly a kind of Chinese medicine composition for the treatment of hydrocephalus, cerebral edema and intracranial hypertension.
Background technology
Modern medicine treatment hydrocephalus mainly adopts the agent of oral agents urine, hormone medicine, can only the respite symptom, and this type of medicine has a lot of side effect to human body, and clinical use has objection.Another kind method adopts operation downcomer drainage treatment, the operation downcomer except meet accident easily and complication, maximum drawback is once thoroughly to finish, and needs regular repeat surgery displacement conduit, expense is higher, makes the patient be difficult for accepting.Developed country has now carried out brain endoscope treatment hydrocephalus in the world, though comparatively effectively advanced, this method only is applicable to the patient beyond the communicating hydrocephalus.Theory of Chinese medical science thinks that hydrocephalus belongs to categories such as infantile metopism, headache, dizzy, vomiting, and cerebral edema, intracranial hypertension syndrome are identical with hydrocephalic pathogenesis.Most of clinically hydrocephalic is except syndromes such as the halogen gate-width of performance deficiency of kidney-QI is split, dull expression, listlessness, dribbling urination, shallow complexion, limbs asthenia; Often simultaneously with the blue veins of qi depression to blood stasis expose, headache feeling of fullness in the head, stiff tongue language are held high up, the paralysis of limb fiber crops; Or the turbid resistance network of expectorant, hoodwink nose heave dizzy, the nausea and vomiting due to the key clearly; Thereby think: hydrocephalic generation, be mostly that on the basis of spleen deficiency of kidney-QI formation expectorant is turbid, water wet, obstruction of collaterals by blood stasis, makes brain internal organs venation obstructed, water liquid is stagnated.Therefore, hydrocephalus is that typical deficiency and excess is held the miscellaneous diseases time under the arm, its essence is deficiency in origin and excess in superficiality.So, suitable treating both the principal and secondary aspects of a disease in the treatment.When being the kidney invigorating, spleen invigorating, QI invigorating, in addition diuretic, invigorate blood circulation, eliminate the phlegm, collateral dredging, have one's ideas straightened out.For this reason; in the patent No. is that " 97118736.3 ", name are called in the patent of invention of " the hydrocephalic Chinese medicine preparation of a kind of treatment "; I have proposed a kind of Chinese medicine composition; it is logical 10~30% by Radix Astragali 20~50%, Radix Notoginseng 10~30%, road, Asteriscus Pseudosciaenae 10~30% and Semen Plantaginis are formed medicated powder, this Chinese medicine preparation has benefiting QI for activating blood circulation, collateral dredging diuretic, improves big brain microcirculation, promotes the cerebrospinal fluid absorption, anti-inflammation detumescence, softening adhesion, releasing cerebrospinal fluid circulation disorder, protection and recovery neurocyte function and evident in efficacy, have no side effect.But there are the following problems in clinical practice for this Chinese medicine preparation: 1, diuresis is not obvious, has certain side effect, the therapeutic effect of the whole medicine of influence; 2, anti-frightened, analgesic activity is not obvious.3, can only be based on the treatment hydrocephalus, the cerebral edema that cerebral infarction, cerebral hemorrhage are caused, the therapeutic effect of intracranial hypertension syndrome are not obvious, and the course of treatment is long, takes effect slowly.
Summary of the invention
The objective of the invention is to solve the problems referred to above that prior art exists; provide a kind of diuresis remarkable; anti-frightened; calm; spasmolytic; analgesic activity is obvious; side effect is little; curative effect is short; instant effect; has benefiting QI for activating blood circulation; the collateral dredging diuretic; improve big brain microcirculation; promote cerebrospinal fluid to attract; anti-inflammation detumescence; softening adhesion; remove cerebrospinal fluid circulation disorder; protection and recovery neurocyte function can be treated hydrocephalus; intracranial hypertension syndrome due to cerebral edema and a variety of causes and treatment hydrocephalus evident in efficacy; the Chinese medicine composition of cerebral edema and intracranial hypertension.
The Chinese medicine composition of this treatment hydrocephalus, cerebral edema and intracranial hypertension is made up of Asteriscus Pseudosciaenae 10~30 grams, Radix Astragali 15~100 grams, living Rhizoma Alismatis 5~25 grams, Poria 10~50 grams, Semen Plantaginis 10~30 grams, Radix Notoginseng 10~40 grams, Radix Salviae Miltiorrhizae 10~100 grams, Fructus Liquidambaris 10~30 grams, Rhizoma Acori Graminei 10~30 grams, Fructus Evodiae 5~25 grams and Radix Achyranthis Bidentatae 10~50 grams.
Advantage of the present invention is:
1, diuresis is remarkable, employing has the Radix Astragali, Radix Notoginseng, Semen Plantaginis, Poria, living Rhizoma Alismatis, Asteriscus Pseudosciaenae, the Radix Achyranthis Bidentatae of diuresis, particularly having row's sodium protects the potassium effect, can prevent to lose the Rhizoma Acori Graminei that potassium causes ion imbalances, the diuresis of this Chinese medicine composition is obviously strengthened, strengthened the overall therapeutic effect of whole medicine, reduce the generation of side effect, can directly reduce cerebrospinal fluid, reduce cerebral edema, the more important thing is by reducing intracranial pressure, pressure differential between subarachnoid space and the venous sinus is increased, and the quick volume that promotes cerebrospinal fluid to be extruded absorbs.
2, increase the cerebral circulation blood flow, select the Radix Astragali of heart tonifying, blood vessel dilating and crown tremulous pulse effect for use, and can promote brain blood supply, increase the Chinese medicine of cerebral tissue blood flowing filling: Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Achyranthis Bidentatae, can promote brain blood supply, the cerebral blood flow increasing amount, and then cerebrospinal fluid is extruded cranial cavity, reduces the volume of cerebrospinal fluid at intracranial.
3, promote cerebrospinal fluid to increase the foundation of partial circulating, Radix Salviae Miltiorrhizae is the key medicine of microcirculation improvement, and microcirculation blood flow is accelerated, the open number showed increased of capillary network, promote microcirculatory blood flow perfusion of local organization and side to prop up circulation and set up, make the local partial circulating that forms numerous cerebrospinal fluid.
4, anti-inflammation detumescence, the effect that Poria, the Radix Astragali have antiviral, improve body immunity, Asteriscus Pseudosciaenae, living Rhizoma Alismatis, Radix Achyranthis Bidentatae, Rhizoma Acori Graminei also have anti-inflammation detumescence, minimizing to ooze out function, Radix Achyranthis Bidentatae also has the effect that significantly inflammatory disorders is absorbed, and Poria and Radix Salviae Miltiorrhizae can also suppress the effect of capillary permeability.
5, anti-cerebral anoxia, Radix Astragali anti-hypoxia significantly resists cerebral anoxia, and the function that promotes that cranial nerve cell recovers is arranged.Radix Salviae Miltiorrhizae can improve hypoxia-bearing capability, can promote the healing of wound, and damage has obvious protective effect to Radix Notoginseng to the cerebral anoxia perfusion.
6, anti-frightened calm, the Radix Astragali, Radix Notoginseng, Poria, Radix Salviae Miltiorrhizae have the anti-frightened effect of tranquillizing and allaying excitement, particularly owing to increased Rhizoma Acori Graminei, Fructus Evodiae two flavor Chinese medicines, and Rhizoma Acori Graminei have eliminate phlegm for resuscitation, the brain-care effect, calm, spasmolysis is obvious; Fructus Evodiae has the sending down the abnormal ascending QI dehumidifying, draws the descending effect of expectorant, and Fructus Evodiae and Radix Achyranthis Bidentatae compatibility have significant analgesia role, and have promoting blood circulation to restore menstrual flow, conducting blood to flow downwards effect, are all the tying-in messenger drug.Therefore, the adding of Rhizoma Acori Graminei, Fructus Evodiae can be strengthened the calmness of this Chinese medicine composition, anti-frightened, spasmolytic and analgesic activity.
In sum; this treats hydrocephalus; behind all medicine compatibilities of the Chinese medicine composition of cerebral edema and intracranial hypertension; diuresis is remarkable and side effect is little; anti-frightened; calm; spasmolytic; analgesic activity is obvious; can increase the cerebral circulation blood flow; promote the cerebrospinal fluid partial circulating; anti-inflammation detumescence; the antioxygen anoxia; has benefiting QI for activating blood circulation; the collateral dredging diuretic; improve big brain microcirculation; promote cerebrospinal fluid to attract; anti-inflammation detumescence; softening adhesion; remove cerebrospinal fluid circulation disorder; protection and recovery neurocyte function; and have quiet; anti-frightened; spasmolytic; analgesic activity; can treat hydrocephalus; intracranial hypertension syndrome due to cerebral edema and a variety of causes and evident in efficacy; short treating period; instant effect can be made into honeyed pill; the watered pill; capsule; tablet; electuary; oral liquid.
The specific embodiment
Embodiment 1:
Get Asteriscus Pseudosciaenae 10 grams, Radix Astragali 100 grams, living Rhizoma Alismatis 5 grams, Poria 50 grams, Semen Plantaginis 10 grams, Radix Notoginseng 40 grams, Radix Salviae Miltiorrhizae 10 grams, Fructus Liquidambaris 30 grams, Rhizoma Acori Graminei 10 grams, Fructus Evodiae 25 grams and Radix Achyranthis Bidentatae 10 grams.Roll respectively and be fine powder, make this Chinese medicine composition.In powder can directly be made or incapsulating, make capsule; Or through the sterilization of sieving, making pellets by mixing medical powder with honey, every ball weigh 9 grams, and the adult takes each ball, and every day three times is oral; Each half ball of child, every day three times is oral.
Embodiment 2:
Get Asteriscus Pseudosciaenae 30 gram, Radix Astragali 15 grams, livings Rhizoma Alismatis 25 grams, Poria 10 grams, Semen Plantaginis 30 grams, Radix Notoginseng 10 grams, Radix Salviae Miltiorrhizae 100 grams, Fructus Liquidambaris 10 grams, Rhizoma Acori Graminei 30 grams, Fructus Evodiae 5 grams and Radix Achyranthis Bidentatae 50 and restrain, roll respectively and be fine powder, make this Chinese medicine composition.In powder can directly be produced or incapsulating, make capsule; Or through the sterilization of sieving, making pellets by mixing medical powder with honey, every ball weigh 9 grams, and the adult takes each ball, and every day three times is oral; Each half ball of child, every day three times is oral.
Embodiment 3:
Get Asteriscus Pseudosciaenae 20 grams, Radix Astragali 52 grams, living Rhizoma Alismatis 15 grams, Poria 30 grams, Semen Plantaginis 20 grams, Radix Notoginseng 25 grams, Radix Salviae Miltiorrhizae 53 grams, Fructus Liquidambaris 20 grams, Rhizoma Acori Graminei 20 grams, Fructus Evodiae 15 grams and Radix Achyranthis Bidentatae 30 grams.Roll respectively and be fine powder, make this Chinese medicine composition.In powder can directly be produced or incapsulating, make capsule; Or through the sterilization of sieving, making pellets by mixing medical powder with honey, every ball weigh 9 grams, and the adult takes each ball, and every day three times is oral; Each half ball of child, every day three times is oral.

Claims (1)

1, a kind of Chinese medicine composition for the treatment of hydrocephalus, cerebral edema and intracranial hypertension is characterized in that: be made up of Asteriscus Pseudosciaenae 10~30 grams, Radix Astragali 15~100 grams, living Rhizoma Alismatis 5~25 grams, Poria 10~50 grams, Semen Plantaginis 10~30 grams, Radix Notoginseng 10~40 grams, Radix Salviae Miltiorrhizae 10~100 grams, Fructus Liquidambaris 10~30 grams, Rhizoma Acori Graminei 10~30 grams, Fructus Evodiae 5~25 grams and Radix Achyranthis Bidentatae 10~50 grams.
CN 200410082747 2004-11-04 2004-11-04 Chinese traditional medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension Expired - Fee Related CN1259946C (en)

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Application Number Priority Date Filing Date Title
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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100431593C (en) * 2006-11-15 2008-11-12 北京万寿通医药科技有限公司 Chinese medicinal formulation for treating hydrocephalus
CN101337034B (en) * 2008-03-18 2011-04-13 林昱 Oral traditional Chinese preparation for treating craniocerebral injury syndrome and preparation method thereof
CN101559152B (en) * 2009-05-19 2011-09-07 李桂华 Chinese materia medica preparation for treating hydrocephalus and preparation method thereof
CN103721003B (en) * 2013-12-29 2016-06-01 高本安 One treats the hydrocephalic Chinese medicine preparation of kidney-essence deficiency children's
CN104288613A (en) * 2014-11-06 2015-01-21 张传强 Traditional Chinese medicinal preparation for treating cerebrospinal fluid leakage after brain tumor operation and preparation method thereof
CN104510936B (en) * 2014-12-17 2017-10-31 蒋树侠 A kind of medicine for treating encephaledema
CN104857260A (en) * 2015-05-25 2015-08-26 刘伟 Traditional Chinese medicine preparation for treating encephaledema and preparation method of traditional Chinese medicine preparation
CN108434380A (en) * 2018-05-02 2018-08-24 湖南汉方博后医疗科技有限公司 It is a kind of to treat hydrocephalic Chinese medicine composition and preparation method thereof

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