CN104857260A - Traditional Chinese medicine preparation for treating encephaledema and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating encephaledema and preparation method of traditional Chinese medicine preparation Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating encephaledema. The traditional Chinese medicine preparation is prepared from raw materials in parts by weight as follows: 30-40 parts of thunberg fritillary bulb, 30-40 parts of astragalus membranaceus, 10-20 parts of gentiana rhodantha, 20-30 parts of indian bread, 30-40 parts of Chinese angelica, 10-20 parts of prepared rehmannia roots, 20-30 parts of rhizome of broadleaf common valeriana, 20-30 parts of danshen roots, 5-15 parts of medcinal evodia fruit, 10-20 parts of honeysuckle flowers, 10-20 parts of buerger pipewort flowers and 10-20 parts of heterophylly falsestarwort roots. The traditional Chinese medicine preparation for treating encephaledema has the functions of qi supplement, promotion of blood circulation, meridian dredging, diuresis inducing, improvement of brain microcirculation, promotion of attraction of cerebrospinal fluids, anti-inflammatory effect, swelling elimination, adhesion softening, elimination of cerebrospinal fluid circulatory barriers, protection and recovery of nerve cells and the like and can treat hypertensive intracranial syndromes caused by encephaledema and other reasons. The medicine is taken orally for three times a day when used for treatment, about 10 g of the medicine is taken each time, 15 days is counted as a treatment course, and encephaledema can be cured usually after two treatment courses.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of cerebral edema and preparation method thereof.
Background technology
Cerebral edema refers to the pathological phenomenon that in brain, moisture increases, causes brain volume to increase, and is the reaction of cerebral tissue to various paathogenic factor.Intracranial hypertension can be caused, injured brain tissue, be common in nervous system disease clinically, as craniocerebral trauma, intracranial infection (encephalitis, meningitis etc.), cerebrovascular disease, Intracranial mass lesion (as tumor), epilepsy and systemic disease are as toxic dysentery, severe pneumonia.
Modern medical therapy cerebral edema mainly adopts oral agents to urinate agent, hormone medicine, can only temporary relief of symptoms, and this type of medicine has a lot of side effect to human body, and Clinical practice has objection.Another kind method adopts operation downcomer drainage treatment, and operation downcomer is except easily meeting accident with except complication, and maximum drawback once thoroughly to complete, and needs regular repeat surgery to replace conduit, costly, patient is not easily accepted.Developed country has carried out brain endoscope treatment cerebral edema now in the world, although comparatively effectively advanced, this method is only applicable to the patient beyond communicating cerebral edema.
Theory of Chinese medical science thinks that cerebral edema belongs to the categories such as infantile metopism, headache, dizzy, vomiting, and hydrocephalus, increased intracranial pressure syndrome are identical with the pathogenesis of cerebral edema.Most of cerebral edema patient is except showing except the disease such as the halogen gate-width of deficiency of kidney-QI is split, dull expression, lethargy, dribbling urination, shallow complexion, limbs asthenia clinically; Often simultaneously with qi depression to blood stasis blue veins exposes, feeling of fullness in the head of have a headache, stiff tongue language are held high up, limb is numb paralyses; Or Phlegm to hinder collaterals, hoodwink nose heave dizzy, nausea and vomiting caused by light key; Thus think: mostly hydrocephalic generation, be on the basis of spleen deficiency of kidney-QI, and formation expectorant is turbid, water wet, obstruction of collaterals by blood stasis, makes brain internal organs venation obstructed, and water liquid is stagnated.Therefore, hydrocephalus is that typical deficiency and excess holds miscellaneous diseases time under the arm, its essence is deficiency in origin and excess in superficiality.Still lack the Chinese medicine preparation that therapeutic effect is used for the treatment of cerebral edema significantly at present.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicine preparation for the treatment of cerebral edema, increased intracranial pressure syndrome caused by cerebral edema and a variety of causes can be treated and evident in efficacy, present invention also offers its preparation method.
The present invention is achieved by the following technical solutions:
Treating a Chinese medicine preparation for cerebral edema, is be made up of the crude drug of following weight portion: Bulbus Fritillariae Thunbergii 30 ~ 40 parts, the Radix Astragali 30 ~ 40 parts, red Radix Gentianae 10 ~ 20 parts, 20 ~ 30 parts, Poria, Radix Angelicae Sinensis 30 ~ 40 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 20 ~ 30 parts, Radix Salviae Miltiorrhizae 20 ~ 30 parts, Fructus Evodiae 5 ~ 15 parts, Flos Lonicerae 10 ~ 20 parts, Flos Eriocauli 10 ~ 20 parts, Radix Pseudostellariae 10 ~ 20 parts.
Preferably, be made up of the crude drug of following weight portion: Bulbus Fritillariae Thunbergii 35 parts, the Radix Astragali 35 parts, red Radix Gentianae 15 parts, 25 parts, Poria, Radix Angelicae Sinensis 35 parts, 15 parts, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 25 parts, Radix Salviae Miltiorrhizae 25 parts, Fructus Evodiae 10 parts, Flos Lonicerae 15 parts, Flos Eriocauli 15 parts, Radix Pseudostellariae 15 parts.
The preparation method of the Chinese medicine preparation of described treatment cerebral edema is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates.
The Chinese medicine preparation for the treatment of cerebral edema of the present invention; there is benefiting QI for activating blood circulation, dredging collateral diuretic, improve large brain microcirculation, promote cerebrospinal fluid attraction, anti-inflammation detumescence, softening adhesion; remove the function such as cerebrospinal fluid circulation disorder, protection & restoration neurocyte, the increased intracranial pressure syndrome caused by cerebral edema and a variety of causes can be treated.During treatment, oral, every day three times, each about 10 grams.15 days courses for the treatment of, usual 2 courses for the treatment of can cure.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares the medicine for the treatment of cerebral edema
Formula is: Bulbus Fritillariae Thunbergii 35 grams, the Radix Astragali 35 grams, red Radix Gentianae 15 grams, 25 grams, Poria, Radix Angelicae Sinensis 35 grams, 15 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 25 grams, Radix Salviae Miltiorrhizae 25 grams, Fructus Evodiae 10 grams, Flos Lonicerae 15 grams, Flos Eriocauli 15 grams, Radix Pseudostellariae 15 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 2 prepares the medicine for the treatment of cerebral edema
Formula is: Bulbus Fritillariae Thunbergii 30 grams, the Radix Astragali 30 grams, red Radix Gentianae 20 grams, 30 grams, Poria, Radix Angelicae Sinensis 30 grams, 10 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 30 grams, Radix Salviae Miltiorrhizae 30 grams, Fructus Evodiae 5 grams, Flos Lonicerae 10 grams, Flos Eriocauli 20 grams, Radix Pseudostellariae 20 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 3 prepares the medicine for the treatment of cerebral edema
Formula is: Bulbus Fritillariae Thunbergii 40 grams, the Radix Astragali 40 grams, red Radix Gentianae 10 grams, 20 grams, Poria, Radix Angelicae Sinensis 40 grams, 20 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Fructus Evodiae 15 grams, Flos Lonicerae 20 grams, Flos Eriocauli 10 grams, Radix Pseudostellariae 10 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 4 prepares the medicine for the treatment of cerebral edema
Formula is: Bulbus Fritillariae Thunbergii 32 grams, the Radix Astragali 35 grams, red Radix Gentianae 18 grams, 28 grams, Poria, Radix Angelicae Sinensis 35 grams, 13 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 25 grams, Radix Salviae Miltiorrhizae 23 grams, Fructus Evodiae 11 grams, Flos Lonicerae 14 grams, Flos Eriocauli 17 grams, Radix Pseudostellariae 12 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 5 prepares the medicine for the treatment of cerebral edema
Formula is: Bulbus Fritillariae Thunbergii 37 grams, the Radix Astragali 32 grams, red Radix Gentianae 12 grams, 24 grams, Poria, Radix Angelicae Sinensis 37 grams, 18 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 23 grams, Radix Salviae Miltiorrhizae 26 grams, Fructus Evodiae 8 grams, Flos Lonicerae 18 grams, Flos Eriocauli 12 grams, Radix Pseudostellariae 14 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Clinical data:
Basic document: patient 237 example, is inpatient, all suffers from cerebral edema, all meets nineteen ninety-five the 4th the cerebrovascular academic conference in the whole nation, and existing tentative tcm diagnosis standard, gets rid of by comatose patient and with the patient of serious Organ Failure.Wherein, man 142 example, female 95 example, 43 ~ 78 years old age.
Therapeutic Method: 237 routine patients, are divided into two groups at random: matched group (117 example) and treatment group (120 example), wherein, matched group adopts merely mannitol Drug therapy: first three day every day 500ml, then four day every day 250ml, rear inactive.The medicine that treatment group adopts embodiment 1 to prepare is treated, oral, every day three times, each 10 grams.15 days courses for the treatment of, observe after treating two courses for the treatment of and add up curative effect.
Therapeutic outcome: the routine patient of matched group 117,11 examples of fully recovering (9.4%), effective 29 examples (24.8%), effective 37 examples (31.6%), invalid 40 examples (34.2%), total effective rate 65.8%, (complication refers to the renal failure occurred in therapeutic process, hematuria) 3 that develop complications in treatment is routine.Treatment group 120 example, 44 examples of fully recovering (36.7%), effective 32 examples (26.7%), effective 42 examples (35.0%), invalid 2 examples (1.7%), total effective rate 98.3%, develop complications in treatment 0 example.
Conclusion: prepared by the embodiment of the present invention 1 Drug therapy cerebral edema Be very effective, be obviously better than mannitol.
Case 1: Korea Spro so-and-so, man, 53 years old.Suffer from the cerebral tumor, vomit, be diagnosed as severe cerebral edema after carrying out gamma knife treatment, defeated 3 days mannitol has no improvement, then, takes the medicine prepared by the embodiment of the present invention 1, oral, every day three times, each 10 grams.After 15 days, symptom is obviously improved, and continues to take 15 days consolidate curative effect.Follow up a case by regular visits to after 1 year, all are normal, do not occur any relapse indications.
Case 2: Tan, man, 56 years old.Suffer from the cerebral tumor, occur after gamma knife treatment headache, vomiting, uncomfortable in chest, breathe hard, excited uneasy.Suffer from severe cerebral edema after diagnosing, take the medicine prepared by the embodiment of the present invention 1, oral, every day three times, each 10 grams.After taking medicine two weeks, symptom was improved, and continues to take 15 days, transference cure, recovery from illness.Follow up a case by regular visits to after 1 year, all are normal for this patient.
Claims (7)
1. treat a Chinese medicine preparation for cerebral edema, it is characterized in that: be made up of the crude drug of following weight portion: Bulbus Fritillariae Thunbergii 30 ~ 40 parts, the Radix Astragali 30 ~ 40 parts, red Radix Gentianae 10 ~ 20 parts, 20 ~ 30 parts, Poria, Radix Angelicae Sinensis 30 ~ 40 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 20 ~ 30 parts, Radix Salviae Miltiorrhizae 20 ~ 30 parts, Fructus Evodiae 5 ~ 15 parts, Flos Lonicerae 10 ~ 20 parts, Flos Eriocauli 10 ~ 20 parts, Radix Pseudostellariae 10 ~ 20 parts.
2. the Chinese medicine preparation of the treatment cerebral edema according to claim, is characterized in that: be made up of the crude drug of following weight portion: Bulbus Fritillariae Thunbergii 35 parts, the Radix Astragali 35 parts, red Radix Gentianae 15 parts, 25 parts, Poria, Radix Angelicae Sinensis 35 parts, 15 parts, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 25 parts, Radix Salviae Miltiorrhizae 25 parts, Fructus Evodiae 10 parts, Flos Lonicerae 15 parts, Flos Eriocauli 15 parts, Radix Pseudostellariae 15 parts.
3. the Chinese medicine of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: Bulbus Fritillariae Thunbergii 30 grams, the Radix Astragali 30 grams, red Radix Gentianae 20 grams, 30 grams, Poria, Radix Angelicae Sinensis 30 grams, 10 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 30 grams, Radix Salviae Miltiorrhizae 30 grams, Fructus Evodiae 5 grams, Flos Lonicerae 10 grams, Flos Eriocauli 20 grams, Radix Pseudostellariae 20 grams.
4. the Chinese medicine of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: Bulbus Fritillariae Thunbergii 40 grams, the Radix Astragali 40 grams, red Radix Gentianae 10 grams, 20 grams, Poria, Radix Angelicae Sinensis 40 grams, 20 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 2 grams, Radix Salviae Miltiorrhizae 20 grams, Fructus Evodiae 15 grams, Flos Lonicerae 20 grams, Flos Eriocauli 10 grams, Radix Pseudostellariae 10 grams.
5. the medicine of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: Bulbus Fritillariae Thunbergii 32 grams, the Radix Astragali 35 grams, red Radix Gentianae 18 grams, 28 grams, Poria, Radix Angelicae Sinensis 35 grams, 13 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 25 grams, Radix Salviae Miltiorrhizae 23 grams, Fructus Evodiae 11 grams, Flos Lonicerae 14 grams, Flos Eriocauli 17 grams, Radix Pseudostellariae 12 grams.
6. the medicine of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: Bulbus Fritillariae Thunbergii 37 grams, the Radix Astragali 32 grams, red Radix Gentianae 12 grams, 24 grams, Poria, Radix Angelicae Sinensis 37 grams, 18 grams, Radix Rehmanniae Preparata, Rhizoma valerianae latifoliae 23 grams, Radix Salviae Miltiorrhizae 26 grams, Fructus Evodiae 8 grams, Flos Lonicerae 18 grams, Flos Eriocauli 12 grams, Radix Pseudostellariae 14 grams.
7. the preparation method of the Chinese medicine preparation of the treatment cerebral edema described in claim 1 ~ 6, is characterized in that: get each raw material, dries, grinds as fine powder, and mixing mixing, incapsulates, to obtain final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213750A (en) * | 2015-11-06 | 2016-01-06 | 张新华 | A kind of pharmaceutical composition for the treatment of cerebral edema |
| CN105412759A (en) * | 2015-10-08 | 2016-03-23 | 孟令霞 | Compound preparation for treating hydrocephalus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1212159A (en) * | 1997-09-20 | 1999-03-31 | 谢静 | Asteriscus Pseudosciaenae pill and instant powder |
| CN1634385A (en) * | 2004-11-04 | 2005-07-06 | 谢静 | Chinese traditional medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension |
| CN102441136A (en) * | 2010-10-15 | 2012-05-09 | 李得中 | Traditional Chinese medicine composition for treating encephaledema and preparation method thereof |
-
2015
- 2015-05-25 CN CN201510269998.XA patent/CN104857260A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1212159A (en) * | 1997-09-20 | 1999-03-31 | 谢静 | Asteriscus Pseudosciaenae pill and instant powder |
| CN1634385A (en) * | 2004-11-04 | 2005-07-06 | 谢静 | Chinese traditional medicine composition for treating hydrocephalus, cerebral edema and intracranial hypertension |
| CN102441136A (en) * | 2010-10-15 | 2012-05-09 | 李得中 | Traditional Chinese medicine composition for treating encephaledema and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412759A (en) * | 2015-10-08 | 2016-03-23 | 孟令霞 | Compound preparation for treating hydrocephalus |
| CN105213750A (en) * | 2015-11-06 | 2016-01-06 | 张新华 | A kind of pharmaceutical composition for the treatment of cerebral edema |
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