CN104940842A - Traditional Chinese medicine combination for treating cerebral edema - Google Patents
Traditional Chinese medicine combination for treating cerebral edema Download PDFInfo
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- CN104940842A CN104940842A CN201510419277.2A CN201510419277A CN104940842A CN 104940842 A CN104940842 A CN 104940842A CN 201510419277 A CN201510419277 A CN 201510419277A CN 104940842 A CN104940842 A CN 104940842A
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Abstract
The invention discloses a traditional Chinese medicine combination for treating cerebral edema. The traditional Chinese medicine combination for treating the cerebral edema is prepared by the following crude drugs of, by weight, 30-40 parts of common anemarrhena rhizome, 30-40 parts of motherwort, 30-40 parts of polygonum cuspidatum, 15-25 parts of elecampane inula roots, 25-35 parts of roots of Chinese thorowax, 5-15 parts of spreading hedyotis herbs, 5-15 parts of coix seeds, 10-20 parts of bighead atractylodes rhizome, 20-30 parts of oriental stephania roots, 20-30 parts of Asiatic pennywort herbs, 20-30 parts of turmeric root tubers, 10-20 parts of alchemilla and 10-20 parts of lightyellow sophora roots. The traditional Chinese medicine combination for treating the cerebral edema achieves the functions of supplementing qi and activating blood circulation, dredging collateral and inducing diuresis, improving brain microcirculation, promoting cerebrospinal fluid attraction, anti-inflammation and detumescence, softening adhesion, reliving cerebrospinal fluid circulatory disturbance, protecting and recovering nerve cells and the like, and the increased intracranial pressure syndrome caused by the cerebral edema and various reasons can be treated. In treatment, the traditional Chinese medicine combination for treating the cerebral edema is taken orally three times a day and about five grams every time. One course of treatment is 15 days, and the cerebral edema can be cured by two courses of the treatment usually.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of cerebral edema.
Background technology
Cerebral edema refers to the pathological phenomenon that in brain, moisture increases, causes brain volume to increase, and is the reaction of cerebral tissue to various paathogenic factor.Intracranial hypertension can be caused, injured brain tissue, be common in nervous system disease clinically, as craniocerebral trauma, intracranial infection (encephalitis, meningitis etc.), cerebrovascular disease, Intracranial mass lesion (as tumor), epilepsy and systemic disease are as toxic dysentery, severe pneumonia.
Modern medical therapy cerebral edema mainly adopts oral agents to urinate agent, hormone medicine, can only temporary relief of symptoms, and this type of medicine has a lot of side effect to human body, and Clinical practice has objection.Another kind method adopts operation downcomer drainage treatment, and operation downcomer is except easily meeting accident with except complication, and maximum drawback once thoroughly to complete, and needs regular repeat surgery to replace conduit, costly, patient is not easily accepted.Developed country has carried out brain endoscope treatment cerebral edema now in the world, although comparatively effectively advanced, this method is only applicable to the patient beyond communicating cerebral edema.
Theory of Chinese medical science thinks that cerebral edema belongs to the categories such as infantile metopism, headache, dizzy, vomiting, and hydrocephalus, increased intracranial pressure syndrome are identical with the pathogenesis of cerebral edema.Most of cerebral edema patient is except showing except the disease such as the halogen gate-width of deficiency of kidney-QI is split, dull expression, lethargy, dribbling urination, shallow complexion, limbs asthenia clinically; Often simultaneously with qi depression to blood stasis blue veins exposes, feeling of fullness in the head of have a headache, stiff tongue language are held high up, limb is numb paralyses; Or Phlegm to hinder collaterals, hoodwink nose heave dizzy, nausea and vomiting caused by light key; Thus think: mostly hydrocephalic generation, be on the basis of spleen deficiency of kidney-QI, and formation expectorant is turbid, water wet, obstruction of collaterals by blood stasis, makes brain internal organs venation obstructed, and water liquid is stagnated.Therefore, hydrocephalus is that typical deficiency and excess holds miscellaneous diseases time under the arm, its essence is deficiency in origin and excess in superficiality.Still lack the medicine that therapeutic effect is used for the treatment of cerebral edema significantly at present.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicine composition for the treatment of cerebral edema, increased intracranial pressure syndrome caused by cerebral edema and a variety of causes can be treated and evident in efficacy, present invention also offers its preparation method.
The present invention is achieved by the following technical solutions:
Treating a Chinese medicine composition for cerebral edema, is be made up of the crude drug of following weight portion: the Rhizoma Anemarrhenae 30 ~ 40 parts, Herba Leonuri 30 ~ 40 parts, Rhizoma Polygoni Cuspidati 30 ~ 40 parts, Radix Inulae 15 ~ 25 parts, Radix Bupleuri 25 ~ 35 parts, Herba Hedyotidis Diffusae 5 ~ 15 parts, Semen Coicis 5 ~ 15 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, Radix Stephaniae Cepharanthae 20 ~ 30 parts, Herba Centellae 20 ~ 30 parts, Radix Curcumae 20 ~ 30 parts, duck's-foot 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts.
Preferably, be made up of the crude drug of following weight portion: the Rhizoma Anemarrhenae 35 parts, Herba Leonuri 35 parts, Rhizoma Polygoni Cuspidati 35 parts, Radix Inulae 20 parts, Radix Bupleuri 30 parts, Herba Hedyotidis Diffusae 10 parts, Semen Coicis 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Stephaniae Cepharanthae 25 parts, Herba Centellae 25 parts, Radix Curcumae 25 parts, duck's-foot 15 parts, Radix Sophorae Flavescentis 15 parts.
The preparation method of the Chinese medicine composition of described treatment cerebral edema is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates.
The Chinese medicine composition for the treatment of cerebral edema of the present invention; there is benefiting QI for activating blood circulation, dredging collateral diuretic, improve large brain microcirculation, promote cerebrospinal fluid attraction, anti-inflammation detumescence, softening adhesion; remove the function such as cerebrospinal fluid circulation disorder, protection & restoration neurocyte, the increased intracranial pressure syndrome caused by cerebral edema and a variety of causes can be treated.During treatment, oral, every day three times, each about 5 grams.15 days courses for the treatment of, usual 2 courses for the treatment of can cure.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares the Chinese medicine composition for the treatment of cerebral edema
Formula is: the Rhizoma Anemarrhenae 35 grams, Herba Leonuri 35 grams, Rhizoma Polygoni Cuspidati 35 grams, the upper Radix Aucklandiae 20 grams, Radix Bupleuri 30 grams, Herba Hedyotidis Diffusae 10 grams, Semen Coicis 10 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Stephaniae Cepharanthae 25 grams, Herba Centellae 25 grams, Radix Curcumae 25 grams, duck's-foot 15 grams, Radix Sophorae Flavescentis 15 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 2 prepares the Chinese medicine composition for the treatment of cerebral edema
Formula is: the Rhizoma Anemarrhenae 30 grams, Herba Leonuri 40 grams, Rhizoma Polygoni Cuspidati 40 grams, Radix Inulae 15 grams, Radix Bupleuri 35 grams, Herba Hedyotidis Diffusae 5 grams, Semen Coicis 5 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Radix Stephaniae Cepharanthae 30 grams, Herba Centellae 20 grams, Radix Curcumae 20 grams, duck's-foot 20 grams, Radix Sophorae Flavescentis 20 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 3 prepares the Chinese medicine composition for the treatment of cerebral edema
Formula is: the Rhizoma Anemarrhenae 40 grams, Herba Leonuri 30 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix Inulae 25 grams, Radix Bupleuri 25 grams, Herba Hedyotidis Diffusae 15 grams, Semen Coicis 15 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Stephaniae Cepharanthae 20 grams, Herba Centellae 30 grams, Radix Curcumae 30 grams, duck's-foot 10 grams, Radix Sophorae Flavescentis 10 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 4 prepares the Chinese medicine composition for the treatment of cerebral edema
Formula is: the Rhizoma Anemarrhenae 33 grams, Herba Leonuri 37 grams, Rhizoma Polygoni Cuspidati 34 grams, Radix Inulae 19 grams, Radix Bupleuri 31 grams, Herba Hedyotidis Diffusae 10 grams, Semen Coicis 7 grams, the Rhizoma Atractylodis Macrocephalae 16 grams, Radix Stephaniae Cepharanthae 23 grams, Herba Centellae 26 grams, Radix Curcumae 25 grams, duck's-foot 12 grams, Radix Sophorae Flavescentis 15 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Embodiment 5 prepares the Chinese medicine composition for the treatment of cerebral edema
Formula is: the Rhizoma Anemarrhenae 38 grams, Herba Leonuri 31 grams, Rhizoma Polygoni Cuspidati 36 grams, Radix Inulae 22 grams, Radix Bupleuri 29 grams, Herba Hedyotidis Diffusae 11 grams, Semen Coicis 13 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Stephaniae Cepharanthae 25 grams, Herba Centellae 22 grams, Radix Curcumae 27 grams, duck's-foot 16 grams, Radix Sophorae Flavescentis 18 grams.
Preparation method is: get each raw material, dries, grinds as fine powder, crosses 120 mesh sieves, and mixing mixing, incapsulates, to obtain final product.
Clinical data:
Basic document: patient 184 example, is inpatient, all suffers from cerebral edema, all meets nineteen ninety-five the 4th the cerebrovascular academic conference in the whole nation, and existing tentative tcm diagnosis standard, gets rid of by comatose patient and with the patient of serious Organ Failure.Wherein, man 103 example, female 81 example, 45 ~ 75 years old age.
Therapeutic Method: 184 routine patients, are divided into two groups at random: matched group (90 example) and treatment group (94 example), wherein, matched group adopts merely mannitol Drug therapy: first three day every day 500ml, then four day every day 250ml, rear inactive.The medicine that treatment group adopts embodiment 1 to prepare is treated, oral, every day three times, each 5 grams.15 days courses for the treatment of, observe after treating two courses for the treatment of and add up curative effect.
Therapeutic outcome: the routine patient of matched group 90,8 examples of fully recovering (8.9%), effective 22 examples (24.4%), effective 29 examples (32.2%), invalid 31 examples (34.4%), total effective rate 65.6%, (complication refers to the renal failure occurred in therapeutic process, hematuria) 3 that develop complications in treatment is routine.
Treatment group 94 example, 34 examples of fully recovering (36.2%), effective 25 examples (26.6%), effective 33 examples (35.1%), invalid 2 examples (2.1%), total effective rate 97.9%, develop complications in treatment 0 example.
Conclusion: the Drug therapy cerebral edema Be very effective prepared by the embodiment of the present invention 1, is obviously better than mannitol.
Case 1: beam, man, 58 years old.Suffer from the cerebral tumor, vomit, be diagnosed as severe cerebral edema after carrying out gamma knife treatment, defeated 3 days mannitol has no improvement.Then, take the medicine prepared by the embodiment of the present invention 1, oral, every day three times, each 5 grams.After 20 days, symptom is obviously improved, and continues to take 10 days consolidate curative effect.Follow up a case by regular visits to after 1 year, all are normal, do not occur any relapse indications.
Case 2: Liu so-and-so, man, 60 years old.Suffer from the cerebral tumor, occur after gamma knife treatment headache, vomiting, uncomfortable in chest, breathe hard, excited uneasy; Suffer from severe cerebral edema after diagnosing.Take the medicine prepared by the embodiment of the present invention 1, oral, every day three times, each 5 grams.Take medicine latter 15 days, symptom is improved, and continues to take 15 days, transference cure, recovery from illness.Follow up a case by regular visits to after 1 year, all are normal for this patient.
Claims (7)
1. treat a Chinese medicine composition for cerebral edema, it is characterized in that: be made up of the crude drug of following weight portion: the Rhizoma Anemarrhenae 30 ~ 40 parts, Herba Leonuri 30 ~ 40 parts, Rhizoma Polygoni Cuspidati 30 ~ 40 parts, Radix Inulae 15 ~ 25 parts, Radix Bupleuri 25 ~ 35 parts, Herba Hedyotidis Diffusae 5 ~ 15 parts, Semen Coicis 5 ~ 15 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, Radix Stephaniae Cepharanthae 20 ~ 30 parts, Herba Centellae 20 ~ 30 parts, Radix Curcumae 20 ~ 30 parts, duck's-foot 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts.
2. the Chinese medicine composition of the treatment cerebral edema according to claim, is characterized in that: be made up of the crude drug of following weight portion: the Rhizoma Anemarrhenae 35 parts, Herba Leonuri 35 parts, Rhizoma Polygoni Cuspidati 35 parts, Radix Inulae 20 parts, Radix Bupleuri 30 parts, Herba Hedyotidis Diffusae 10 parts, Semen Coicis 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Stephaniae Cepharanthae 25 parts, Herba Centellae 25 parts, Radix Curcumae 25 parts, duck's-foot 15 parts, Radix Sophorae Flavescentis 15 parts.
3. the Chinese medicine composition of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: the Rhizoma Anemarrhenae 30 grams, Herba Leonuri 40 grams, Rhizoma Polygoni Cuspidati 40 grams, Radix Inulae 15 grams, Radix Bupleuri 35 grams, Herba Hedyotidis Diffusae 5 grams, Semen Coicis 5 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Radix Stephaniae Cepharanthae 30 grams, Herba Centellae 20 grams, Radix Curcumae 20 grams, duck's-foot 20 grams, Radix Sophorae Flavescentis 20 grams.
4. the Chinese medicine composition of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: the Rhizoma Anemarrhenae 40 grams, Herba Leonuri 30 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix Inulae 25 grams, Radix Bupleuri 25 grams, Herba Hedyotidis Diffusae 15 grams, Semen Coicis 15 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Stephaniae Cepharanthae 20 grams, Herba Centellae 30 grams, Radix Curcumae 30 grams, duck's-foot 10 grams, Radix Sophorae Flavescentis 10 grams.
5. the Chinese medicine composition of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: the Rhizoma Anemarrhenae 33 grams, Herba Leonuri 37 grams, Rhizoma Polygoni Cuspidati 34 grams, Radix Inulae 19 grams, Radix Bupleuri 31 grams, Herba Hedyotidis Diffusae 10 grams, Semen Coicis 7 grams, the Rhizoma Atractylodis Macrocephalae 16 grams, Radix Stephaniae Cepharanthae 23 grams, Herba Centellae 26 grams, Radix Curcumae 25 grams, duck's-foot 2 grams, Radix Sophorae Flavescentis 15 grams.
6. the Chinese medicine composition of the treatment cerebral edema according to claim, is characterized in that: be made up of following crude drug: the Rhizoma Anemarrhenae 38 grams, Herba Leonuri 31 grams, Rhizoma Polygoni Cuspidati 36 grams, Radix Inulae 22 grams, Radix Bupleuri 29 grams, Herba Hedyotidis Diffusae 11 grams, Semen Coicis 13 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Stephaniae Cepharanthae 25 grams, Herba Centellae 22 grams, Radix Curcumae 27 grams, duck's-foot 16 grams, Radix Sophorae Flavescentis 18 grams.
7. the preparation method of the Chinese medicine composition of the treatment cerebral edema described in claim 1 ~ 6, is characterized in that: get each raw material, dries, grinds as fine powder, and mixing mixing, incapsulates, to obtain final product.
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| CN201510419277.2A CN104940842A (en) | 2015-07-16 | 2015-07-16 | Traditional Chinese medicine combination for treating cerebral edema |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213750A (en) * | 2015-11-06 | 2016-01-06 | 张新华 | A kind of pharmaceutical composition for the treatment of cerebral edema |
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| JPH06228009A (en) * | 1993-01-29 | 1994-08-16 | Setsuo Hokogahara | Medicine for preventing kind of human congenital abnormality, containing akabane virus and bordetella bronchiseptica and its use |
| CN1772052A (en) * | 2005-11-02 | 2006-05-17 | 广州中医药大学第二附属医院 | Chinese medicine composition for treating cerebral hemorrhage and its prepn |
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- 2015-07-16 CN CN201510419277.2A patent/CN104940842A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06228009A (en) * | 1993-01-29 | 1994-08-16 | Setsuo Hokogahara | Medicine for preventing kind of human congenital abnormality, containing akabane virus and bordetella bronchiseptica and its use |
| CN1772052A (en) * | 2005-11-02 | 2006-05-17 | 广州中医药大学第二附属医院 | Chinese medicine composition for treating cerebral hemorrhage and its prepn |
Non-Patent Citations (1)
| Title |
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| 宋良鹏等: ""补阳还五汤加味治疗创伤性脑水肿临床观察"", 《山东中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213750A (en) * | 2015-11-06 | 2016-01-06 | 张新华 | A kind of pharmaceutical composition for the treatment of cerebral edema |
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