CN1256128C - Eye disease treating medicine - Google Patents
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- CN1256128C CN1256128C CN 200310121654 CN200310121654A CN1256128C CN 1256128 C CN1256128 C CN 1256128C CN 200310121654 CN200310121654 CN 200310121654 CN 200310121654 A CN200310121654 A CN 200310121654A CN 1256128 C CN1256128 C CN 1256128C
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Abstract
The present invention relates to a medicine for treating eye diseases, particularly to a 'compound light particle' which can be used for treating ophthalmology diseases, such as central serous chorioretinopathy, vitreous opacity, optic atrophy, etc. The medicine of the present invention comprises fifteen Chinese herbal medicines of Chinese angelica, radix paeoniae alba, tuckahoe, atractylodes macrocephala, red sage roots, radix bupleuri, prepared rhizome of rehmannia, Chinese yam, etc.; after a boiling process, a concentrating process, a granulating process, a drying process, a sterilizing process, a packing process, etc. are carried out for the fifteen Chinese herbal medicines, a finished product of the medicine of the present invention is formed. The medicine of the present invention has the efficiency of nourishing kidneys, nourishing livers, dispersing wind and improving eyesight, and has obvious curative effects on ophthalmology diseases, such as the central serous chorioretinopathy, the vitreous opacity, the optic atrophy, etc.
Description
Technical field: the present invention relates to a kind of medicine for the treatment of disease of eye, " the compound light granule " of ophthalmic diseasess such as a kind of specifically therapeutic community's property serosity venation retinopathy, vitreous opacity, optic atrophy.
Background technology: ophthalmic diseasess such as therapeutic community's property serosity venation retinopathy, vitreous opacity, optic atrophy at present, doctor trained in Western medicine does not still have the good curing method, the concrete method that adopts is western medical treatment central serous chorioretinopathy and the oral lecithin chelated iodine of vitreous opacity, the intramuscular injection prolonium iodide.The treatment optic atrophy adopts vitamins and angiectatic medicine etc., but above-mentioned Therapeutic Method can only play mitigation, cures the symptoms, not the disease, and also there is the problem of the one-sidedness aspect of treatment in other dosage forms of the traditional Chinese medical science.
Summary of the invention: the objective of the invention is in order to overcome the deficiencies in the prior art, provide a kind of can therapeutic community's property serosity venation retinopathy, the Chinese medicine of ophthalmic diseases such as vitreous opacity, optic atrophy.
In order to achieve the above object, technical scheme of the present invention is:
Medicine of the present invention is made (consumption is a weight portion) by following component
Radix Angelicae Sinensis 10-13 part Radix Paeoniae Alba 14-18 part Poria 18-22 part
Rhizoma Atractylodis Macrocephalae 23-27 part Radix Salviae Miltiorrhizae 11-13 part Radix Bupleuri 18-22 part
Radix Rehmanniae Preparata 18-22 part Rhizoma Dioscoreae 14-18 part Radix Rehmanniae 18-22 part
Fructus Lycii 23-27 part Magnetitum 14-18 part Fructus Gardeniae 10-13 part
Rhizoma Cimicifugae 10-12 part Fructus Schisandrae Chinensis 10-13 part Radix Glycyrrhizae 6-10 part
Medicine optimum weight proportioning of the present invention is:
25 parts of 20 parts of Rhizoma Atractylodis Macrocephalaes of 16 parts of Poria of 12 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
16 parts of 20 portions of Rhizoma Dioscoreaes of 20 parts of Radix Rehmanniaes Preparata of 12 parts of Radix Bupleuri of Radix Salviae Miltiorrhizae
12 parts of 16 portions of Fructus Gardeniaes of 25 parts of Magnetitums of 20 parts of Fructus Lycii of the Radix Rehmanniae
8 parts in 12 portions of Radix Glycyrrhizaes of 12 parts of Fructus Schisandrae Chinensis of Rhizoma Cimicifugae
The method of above-mentioned each component being made medicine of the present invention is: above-mentioned ten five tastes Chinese herbal medicine are decocted with water three times; 2 hours for the first time; 2 hours for the second time, one hour for the third time, gradation filtered; merging filtrate; static 24 hours, getting supernatant concentration to relative density was 1.35-1.38, and it is an amount of to add cane sugar powder, purified water, ethanol; make granule by granulator, final drying, sterilization, packing promptly get product of the present invention.
The dosage form of product of the present invention is a granule, and character is a dark brown granule, and it is sweet to distinguish the flavor of, little acid, and packing specification is the 10g/ bag, instructions of taking is that boiled water is taken after mixing it with water, each 1 bag, three times on the one.
The effect that medicine of the present invention has nourishing kidney, nourishing the liver, the wind that looses makes eye bright has notable therapeutic effect to ophthalmic diseasess such as central serous chorioretinopathy, vitreous opacity, optic atrophys.
Clinical therapeutic efficacy:
Oculopathy such as central serous chorioretinopathy (this title abbreviates middle slurry as later on), vitreous opacity, optic atrophy, the category of genus motherland's medical science " blurring of vission ", " chromatopsia ", " optic atrohic blindness ".The cause of disease is because hepatic and renal YIN deficiency, the essence and blood consume, can not on hold, order loses due to the self-restraint.
The inventor through clinical observation in 8 years, through contrasting and statistical procedures with matched group, proves that it is evident in efficacy with above-mentioned sufferer 300 examples of Chinese medicine compound light granule therapy.Now clinical research is reported as follows:
1, clinical data: middle slurry, vitreous opacity, each 100 example (100 eyes) of optic atrophy patient are made a definite diagnosis in outpatient service, the men and women does not have significant difference, age 20---70 year, average 45 years old, every kind of disease is divided into two groups at random, compound light granule therapy group (every kind of each 50 example of disease), matched group (every kind of each 50 example of disease) uses western medicine, middle slurry, the oral lecithin chelated iodine of vitreous opacity, the intramuscular injection prolonium iodide, optic atrophy is with vitamin medicaments, as vitamin B1, vitamin B12, vasodilation treatment.
2, Therapeutic Method: the particulate main component of compound light is 15 flavor Chinese medicines such as Radix Angelicae Sinensis, white peony root, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Radix Bupleuri, Radix Rehmanniae Preparata, Rhizoma Dioscoreae, the Radix Rehmanniae, structure Fructus Lycii, Magnetitum, and above-mentioned 15 flavor Chinese medicines are decocted with water two hours for the first time 3 times, two hours for the second time, one hour for the third time, gradation filtered, merging filtrate, static 24 hours, getting supernatant concentration to relative density was 1.35-1.38, adds cane sugar powder, purified water, ethanol is an amount of, makes particle drying, makes 1500 grams, promptly.Each 10 grams, every day 3 times, oral.10 days was 1 course of treatment, and 1-2 observes therapeutic effect the course of treatment, and the observation period is limited to 3 months.
3, observational technique, index and curative effect judging standard: observe indexs such as suffering from eye symptom, sign weekly, curative effect is divided into recovery from illness, produce effects, effective, invalid level Four.Recovery from illness with effectively add up to effectively, be the raising standard of testing eyesight with standard logarithmic visual acuity chart, middle slurry reverts to recovery from illness to recover original vision central fovea of macula luminous reflectance.Improve 3 row with vision, hydrops obviously is absorbed as produce effects under the nethike embrane, improves 1 row with vision, and hydrops obviously is absorbed as effectively under the nethike embrane, vision and optical fundus do not have change into invalid.Vitreous opacity disappears with subjective symptoms, ophthalmoscopy, the eye ultrasound diagnosis is asymptomatic for fully recovering, with subjective symptoms be clearly better, examination of ocular fundus, all to be clearly better be produce effects in an eye ultrasound diagnosis, take a turn for the better with subjective symptoms, ophthalmoscopy, the eye ultrasound diagnosis slightly transfers to well effectively, is invalid with the subjective symptoms no change.Optic atrophy is looked the nipple color and luster and is reverted to recovery from illness to recover original vision, improves 3 row with vision, looks the nipple color and luster and obviously reverts to produce effects, improves 1 row with vision, looks the nipple color and luster and obviously reverts to effectively, with vision and to look nipple color and luster no change be invalid.
4, result
Curative effect is examined and be the results are shown in Table 1,2,3:
Table 1, middle slurry observed result:
| Group | The eye number | Recovery from illness | Produce effects | Effectively | Invalid | Cure rate | Effective percentage |
| The treatment group | 50 | 48 | 2 | 0 | 0 | 96％ | 100％ |
| Matched group | 50 | 30 | 10 | 5 | 5 | 60％ | 90％ |
Table 2, vitreous opacity observed result:
| Group | The eye number | Recovery from illness | Produce effects | Effectively | Invalid | Cure rate | Effective percentage |
| The treatment group | 50 | 41 | 5 | 4 | 0 | 82％ | 100％ |
| Matched group | 50 | 15 | 4 | 3 | 28 | 30％ | 44％ |
Table 3, optic atrophy observed result:
| Group | The eye number | Recovery from illness | Produce effects | Effectively | Invalid | Cure rate | Effective percentage |
| The treatment group | 50 | 20 | 21 | 5 | 4 | 40％ | 92％ |
| Matched group | 50 | 2 | 8 | 5 | 35 | 4％ | 30％ |
From table 1,2,3 as can be seen, treatment group and matched group exist significant difference, and compound light granule therapy produce effects is fast, curative effect is good, are better than simple western modern medicine treatment.
5, model case
Wang Qingfei, man, 50 years old.Guo Jia people from shop, Lishu County.On March 8th, 1999 examined.Conscious right eye metamorphopsia, diminish, muscae genetic vision, surplus the visual deterioration 10 day.Vision: the right side 4.3, a left side 5.0, the shallow disengaging of the big patelliform slurry retina of the visible 3PD of macular area at the bottom of the right eye has reflective swooning on every side, and the central fovea luminous reflectance disappears, and fluorescence fundus angiography is diagnosed as middle slurry, and the primary disease course of disease was generally 3---6 month.It is oral to give compound granular, each 10 grams, and per 3 times, after 20 days, patient's subjective symptoms disappears, vision restoration 5.0, it is normal that recover on the optical fundus, continues with 10 days, as a means of consolidation.
Zhang Wei, man, 39 years old.Guo Jia people from shop, Lishu County, on January 8th, 2000 examined.Shadow is waved before the conscious left eye, blurring of vision half a year.Vision: the right side 5.0, a left side 4.8, several unsetting canescence dregs in the visible vitreous body in optical fundus, an eye ultrasound diagnosis is diagnosed as vitreous opacity.Give the compound light particulate oral, each 10 grams, every day 3 times, after 2 months, patient's subjective symptoms disappears, vision restoration 5.0, ophthalmoscopy, eye ultrasound diagnosis transference cure continues with 10 days, as a means of consolidation.
Li Guirong, woman, 52 years old.The retired cadre, JIUYUE was examined on the 3rd in 1998.Conscious right eye blurring of vision 2 years.Vision: the right side 4.5, a left side 5.0, it is pale that the examination of ocular fundus right eye is looked nipple temporo side color, and the border is clear, retinal vessel normally gives the compound light particulate oral, each 10 grams, and every day 3 times is after 2 months, look the nipple color and luster and recover substantially, vision restoration 5.0 continues with 10 days, as a means of consolidation.
6, discuss
Oculopathy such as middle slurry, vitreous opacity, optic atrophy, the category of genus motherland's medical science " blurring of vission ", " chromatopsia ", " optic atrohic blindness ".How by hepatic and renal YIN deficiency, the essence and blood consume, can not on hold, order loses self-restraint.Insufficiency of kidney-YANG, decline of the fire from the gate of life, vital essence can not sending nutrient upward to eye.Eating and drinking without temperance or impairment caused by overstrain are excessive, and temper is impaired, can not transport to be skillful in order.Seven emotions pent-up, wood are lost bar and are reached, the heart-nutriment loss, the empty consumption of manner, so that eyes being lustreless and spiritless.
" optic atrohic blindness ", blurring of vission ", " chromatopsia " all belong to chronic disease, with the passing of time back two kinds of card marquis are not healed; become the optic atrohic blindness serious symptom; its common feature is that vision and vision change, but are not had the sign of pupil god's distortion and variable color, the conscious vision of optic atrohic blindness person fades, blind at last.The blurring of vission person, the outer observation of eye do not have his disease, and it is conscious that to look thing dusk vast, uncivilized unclear, and chromatopsia person, pupil manner color are normal, shade a slice but the patient has considered oneself as, even present blue green color of a sheet of viridescent or helvolus at the moment.Though more than three diseases on symptom to some extent the difference, because of pathogenesis identical.So method of treatment is identical.Control suitable enriching yin and nourishing kidney, the gentle wood of nourishing the liver, warming and recuperating the kidney-YANG, tonifying Qi and lifting yang.Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Lycii the kidney invigorating and essence nourishing in the side, the training tonifying kidney-yin.The Fructus Gardeniae clearing away heat-damp and promoting diuresis.Radix Angelicae Sinensis, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae invigorating the spleen and benefiting QI.The Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, yang invigorating, the vital essence sending nutrient upward to eye of act Liver and kidney.Radix Salviae Miltiorrhizae has that diffusing heavily fortified point is invigorated blood circulation, the effect of blood stasis dispelling.The Poria promoting diuresis to eliminate damp pathogen.Radix Rehmanniae nourishing the liver and kidney.The Fructus Schisandrae Chinensis nourishing the liver to improve visual acuity.Rhizoma Cimicifugae detoxifcation yang invigorating.Magnetitum improving inspiration by invigorating kidney-QI YANG hyperactivity suppressing.All medicines share, and Baconic consolidates, strengthening body resistance and dispelling evil.Dispersing the stagnated live-QI to relieve the stagnation of QI is arranged, regulating functional activities of qi, the effect of liver and kidney tonifying.Treating both the principal and secondary aspects of a disease, just middle pathogenesis, all disease spontaneous recovery.
Embodiment:
Take by weighing Radix Angelicae Sinensis 120g by proportion of raw materials; Radix Paeoniae Alba 160g; Poria 200g; Rhizoma Atractylodis Macrocephalae 250g; Radix Salviae Miltiorrhizae 120g; Radix Bupleuri 200g; Radix Rehmanniae Preparata 200g; Rhizoma Dioscoreae 160g; Radix Rehmanniae 200g; Fructus Lycii 250g; Magnetitum 160g; Fructus Gardeniae 120g; Rhizoma Cimicifugae 120g; Fructus Schisandrae Chinensis 120g; Radix Glycyrrhizae 80g; above-mentioned ten five tastes Chinese herbal medicine are added decocting firmly to be boiled three times; 2 hours for the first time; 2 hours for the second time; one hour for the third time; gradation filters; merging filtrate; static 24 hours; getting supernatant concentration to relative density is 1.35-1.38; add cane sugar powder; purified water; ethanol is an amount of; make granule by granulator; final drying; sterilization; make 1500g medicinal granule of the present invention, be packaged into the pouch that specification is the 10g/ bag at last.
Claims (2)
1, a kind of medicine for the treatment of oculopathy is characterized in that: it is the granule of being made by following materials of weight proportions:
Radix Angelicae Sinensis 10-13 part Radix Paeoniae Alba 14-18 part Poria 18-22 part
Rhizoma Atractylodis Macrocephalae 23-27 part Radix Salviae Miltiorrhizae 11-13 part Radix Bupleuri 18-22 part
Radix Rehmanniae Preparata 18-22 part Rhizoma Dioscoreae 14-18 part Radix Rehmanniae 18-22 part
Fructus Lycii 23-27 part Magnetitum 14-18 part Fructus Gardeniae 10-13 part
Rhizoma Cimicifugae 10-12 part Fructus Schisandrae Chinensis 10-13 part Radix Glycyrrhizae 6-10 part
Preparation method is: above-mentioned ten five tastes Chinese herbal medicine are decocted with water three times; 2 hours for the first time; 2 hours for the second time, one hour for the third time, gradation filtered; merging filtrate; static 24 hours, getting supernatant concentration to relative density was 1.35-1.38, and it is an amount of to add cane sugar powder, purified water, ethanol; make granule by granulator, final drying, sterilization, packing are promptly.
2, a kind of medicine for the treatment of oculopathy according to claim 1, it is characterized in that: the weight proportion of each raw material is:
25 parts of 20 parts of Rhizoma Atractylodis Macrocephalaes of 16 parts of Poria of 12 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
16 parts of 20 portions of Rhizoma Dioscoreaes of 20 parts of Radix Rehmanniaes Preparata of 12 parts of Radix Bupleuri of Radix Salviae Miltiorrhizae
12 parts of 16 portions of Fructus Gardeniaes of 25 parts of Magnetitums of 20 parts of Fructus Lycii of the Radix Rehmanniae
8 parts in 12 portions of Radix Glycyrrhizaes of 12 parts of Fructus Schisandrae Chinensis of Rhizoma Cimicifugae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310121654 CN1256128C (en) | 2003-12-30 | 2003-12-30 | Eye disease treating medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310121654 CN1256128C (en) | 2003-12-30 | 2003-12-30 | Eye disease treating medicine |
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| Publication Number | Publication Date |
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| CN1634195A CN1634195A (en) | 2005-07-06 |
| CN1256128C true CN1256128C (en) | 2006-05-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200310121654 Expired - Lifetime CN1256128C (en) | 2003-12-30 | 2003-12-30 | Eye disease treating medicine |
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| CN (1) | CN1256128C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178815B (en) * | 2011-04-10 | 2012-03-21 | 刘永华 | Traditional Chinese medicine for treating ischemic optic neuropathy |
| CN102641431B (en) * | 2012-05-21 | 2013-07-10 | 修方伟 | Medicament for treating vitreous opacity |
| CN103623128B (en) * | 2013-12-12 | 2015-07-08 | 苏振华 | Medicine for treating optic atrophy and preparation method thereof |
| CN103830497A (en) * | 2014-03-12 | 2014-06-04 | 逄增容 | Traditional Chinese medicine for treating vitreous opacity and preparation method thereof |
| CN104043045B (en) * | 2014-06-20 | 2017-06-06 | 张铭连 | Treat the pharmaceutical composition of optic atrophy |
| CN106668237A (en) * | 2016-08-25 | 2017-05-17 | 吴斌 | Medicine for treating optic atrophy |
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2003
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| CN1634195A (en) | 2005-07-06 |
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