CN1256112C - Chinese traditional medicine preparation for treating cardiac and cerebral vascular diseases and its preparation process - Google Patents
Chinese traditional medicine preparation for treating cardiac and cerebral vascular diseases and its preparation process Download PDFInfo
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- CN1256112C CN1256112C CN 200310105678 CN200310105678A CN1256112C CN 1256112 C CN1256112 C CN 1256112C CN 200310105678 CN200310105678 CN 200310105678 CN 200310105678 A CN200310105678 A CN 200310105678A CN 1256112 C CN1256112 C CN 1256112C
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- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 title claims abstract description 12
- 230000002490 cerebral effect Effects 0.000 title abstract 3
- 230000000747 cardiac effect Effects 0.000 title description 3
- 208000019553 vascular disease Diseases 0.000 title 1
- 241000545744 Hirudinea Species 0.000 claims abstract description 46
- 235000021419 vinegar Nutrition 0.000 claims abstract description 29
- 239000000052 vinegar Substances 0.000 claims abstract description 29
- 235000015099 wheat brans Nutrition 0.000 claims abstract description 23
- 241000219061 Rheum Species 0.000 claims abstract description 22
- 235000009411 Rheum rhabarbarum Nutrition 0.000 claims abstract description 22
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 16
- 235000009566 rice Nutrition 0.000 claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000000203 mixture Substances 0.000 claims abstract description 14
- 239000000843 powder Substances 0.000 claims abstract description 14
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 230000002526 effect on cardiovascular system Effects 0.000 claims abstract description 6
- 208000024172 Cardiovascular disease Diseases 0.000 claims abstract description 5
- 208000026106 cerebrovascular disease Diseases 0.000 claims abstract description 5
- 240000004980 Rheum officinale Species 0.000 claims description 19
- 235000008081 Rheum officinale Nutrition 0.000 claims description 19
- 241000756943 Codonopsis Species 0.000 claims description 18
- 241000209094 Oryza Species 0.000 claims description 14
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- 238000003756 stirring Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 239000000314 lubricant Substances 0.000 claims description 7
- 238000000746 purification Methods 0.000 claims description 7
- 241000237903 Hirudo Species 0.000 claims description 6
- 235000002791 Panax Nutrition 0.000 claims description 2
- 241000208343 Panax Species 0.000 claims description 2
- 235000014101 wine Nutrition 0.000 abstract description 8
- 206010020772 Hypertension Diseases 0.000 abstract description 4
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract description 3
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- 208000029078 coronary artery disease Diseases 0.000 abstract description 3
- 206010047115 Vasculitis Diseases 0.000 abstract description 2
- 201000001421 hyperglycemia Diseases 0.000 abstract description 2
- 208000010125 myocardial infarction Diseases 0.000 abstract description 2
- 231100000915 pathological change Toxicity 0.000 abstract description 2
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- 241000007126 Codonopsis pilosula Species 0.000 abstract 3
- 240000007594 Oryza sativa Species 0.000 abstract 2
- 239000008187 granular material Substances 0.000 abstract 2
- 238000013329 compounding Methods 0.000 abstract 1
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- 201000009925 nephrosclerosis Diseases 0.000 abstract 1
- 238000003672 processing method Methods 0.000 abstract 1
- 239000000779 smoke Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 15
- 210000004369 blood Anatomy 0.000 description 15
- 235000003181 Panax pseudoginseng Nutrition 0.000 description 10
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- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 5
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Abstract
The present invention discloses a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The preparation is basically prepared from codonopsis pilosula, notoginseng, leeches and rhubarb, and more specifically, the preparation contains the following ingredients according to the weight compounding ratio: 39% to 53% of codonopsis pilosula, 17% to 29% of notoginseng, 17% to 27% of leech and 8% to 18% of rhubarb. The preparation method comprises the following steps: the rhubarb is processed according to a processing method with vinegar; clean rhubarb pieces are moistened by rice vinegar; after being taken out, the clean rhubarb pieces are fried by slow fire until a few focal spots occur on the surface; after being taken out, the rhubarb pieces are cooled; 100 grams of rhubarb needs 10 grams of rice vinegar; clean leech threads are adopted and moistened by yellow wine; the leech threads are taken out, and the leech threads and wheat bran peels fried until smoke occurs are fried together; when the leeches are yellow, and special odor escapes, the obtained mixture is taken out; coked bran peels are screened out, and the mixture is cooled; 10 kilograms of leech needs 1 kilogram of yellow wine and 1 kilogram of wheat bran peel; the prepared rhubarb, the prepared leeches, the codonopsis pilosula and the notoginseng are mixed, crushed, pulverized and sieved, pure powder is obtained, the pure powder and 75% of medical ethanol are stirred and mixed, granules are prepared, or a right quantity of lubricating substances is added for controlling the water quantity, and the granules are pressed into tablets. The traditional Chinese medicine preparation is mainly used for treating coronary heart diseases caused by hypertension, hyperlipoidemia and hyperglycemia, myocardial infarction, heart rate malfunction, cerebral apoplexy, cerebral aphrenia, vasculitis, nephrosclerosis, pathological changes of eyeground.
Description
Technical field:
The present invention relates to treat the Chinese medicine preparation and the production method thereof of cardiovascular and cerebrovascular disease.
Background technology:
Treat cardiac cerebral arteriosclerosis in the prior art, hypertension, hyperlipidemia, the blood viscosity height, the prescription drugs of cardiovascular and cerebrovascular disease such as coronary heart disease, the compatibility complexity, recipe quantity is big, exists to take for a long time to cause and be off one's feed drawbacks such as diarrhoea.
Summary of the invention:
The objective of the invention is to overcome above-mentioned the deficiencies in the prior art part, a kind of treatment cardiovascular and cerebrovascular vessel Chinese medicine preparation is provided, it is made up of Radix Codonopsis, Radix Notoginseng, Hirudo, Radix Et Rhizoma Rhei basically, in blood circulation promoting and blood stasis dispelling, emphasizes QI invigorating, simultaneously harmonizing the spleen and stomach.
The objective of the invention is to be achieved through the following technical solutions: be made up of Radix Codonopsis, Radix Notoginseng, Hirudo, Radix Et Rhizoma Rhei basically, weight proportion is a Radix Codonopsis 39%～53%, Radix Notoginseng 17%～29%, Hirudo 17%～27%, Radix Et Rhizoma Rhei 8%～18%.
The preparation method of above-mentioned Chinese medicine preparation is: rheum officinale is pressed the vinegar method for making, and clean rhubarb tablets with the vexed profit of rice vinegar, is taken out rear warm fire and fries to surperficial little band focal spot, cools after the taking-up, and per 100 restrain rheum officinales rice vinegar 10 grams; Get water purification leech silk with yellow rice wine vexed profit, take out with the wheat bran skin of frying when smoldering and stir, take out when leech is yellow and have special odor to overflow, the sieve wheat bran that defocuses cools, and per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; With above-mentioned rhubarb, leech processed, Radix Codonopsis, panax mixed, broken, pulverize, sieve, get clean powder, stir with 75% medicinal alcohol, mix, preparing granular, or add again and be compressed into tablets after the water yield is controlled in the moderate lubrication agent.
The traditional Chinese medical science thinks that hypertension, hyperlipidemia, high blood viscosity, cerebral arteriosclerosis disease reason are worn with age, and it is angry to be worried, and has a liking for food tobacco and wine fat meat and fine grain, savoury, and cause the internal organs imbalance of YIN and YANG, and finally cause QI and blood disorderly contrary, contrary disorderly at brain, be apoplexy.The suitable QI invigorating of Therapeutic Principle is lived the removing blood stasis collateral dredging.Radix Codonopsis is a monarch drug in the side, the QI invigorating blood stasis dispelling, and it is capable to promote blood, impels whole body QI and blood smoothness, brings into play the effect of its nourishing-to-relaxing; Radix Notoginseng is a ministerial drug, blood circulation promoting and blood stasis dispelling, benefiting vital QI and blood; Hirudo is a messenger drug, removing blood stasis, but qualcomm meridian, and assistant is with Radix Et Rhizoma Rhei purging FU-organs intestinal stasis relieving, makes to lose empty healthy energy and replenished, and the blood clots absorbing due to the deficiency of vital energy stagnates, the venation blood stasis, limbs are attached undue importance to one thing to the neglect of the other, and can obtain tonneau and dissipate, and weed out the old and bring forth the new.
Function with cure mainly: young blood, vessel softening, disappear thrombus dissolving and speckle increase brain, cardiac flow, obviously increase the young factor of blood and the arteriosclerosis factor (NO.NOD.SOD), anti-aging effects is remarkable.Cure mainly the coronary heart disease of hypertension, hyperlipidemia, hyperglycemia initiation, myocardial infarction, arrhythmia, apoplexy, brain dementia, vasculitis, renal function sclerosis, optical fundus blood vessel, vessels of internal ear pathological changes, blood high viscosity syndrome, diabetes etc.
Usage and consumption: a 2-4 grain, one day 2-3 time, bfore meals, drink more water.
The specific embodiment:
Embodiment 1
Radix Codonopsis 100 grams, pseudo-ginseng 50 grams, leech 50 grams, rheum officinale 25 grams.Rheum officinale is mixed the clean rhubarb tablets of big or small stepping thoroughly according to the vinegar method for making with rice vinegar, the vexed profit to vinegar exhausted, and puts in the pot, when frying to surperficial little band focal spot by the temperature fire, cools after the taking-up, and per 100 gram rheum officinales are with rice vinegar 10 grams; Get water purification leech silk with yellow rice wine mix thoroughly, vexed profit, the wheat bran skin is sprinkled in the heat pot, pour the leech silk of wine after vexed when to be smoldered into and stir, be yellow to leech silk surface, and take out rapidly when having special odor to overflow, the sieve wheat bran that defocuses cools, per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; Above-mentioned rhubarb, leech processed, pseudo-ginseng, Radix Codonopsis are mixed fragmentation, separating twice, cross 100 mesh sieves, or ultramicro grinding, clean powder got, put in the mixer with 75% ethanol (medicinal), mix above-mentioned clean powder, granulation, in branch is encapsulated, 0.2 gram/grain, or get above-mentioned particle, add the moderate lubrication agent, such as talcum powder (medicinal), dolomol, the control water content is compressed into tablets, every 0.2 gram.
Embodiment 2
Radix Codonopsis 130 grams, pseudo-ginseng 50 grams, leech 50 grams, rheum officinale 25 grams.Rheum officinale is mixed the clean rhubarb tablets of big or small stepping thoroughly according to the vinegar method for making with rice vinegar, the vexed profit to vinegar exhausted, and puts in the pot, when frying to surperficial little band focal spot by the temperature fire, cools after the taking-up, and per 100 gram rheum officinales are with rice vinegar 10 grams; Get water purification leech silk with yellow rice wine mix thoroughly, vexed profit, the wheat bran skin is sprinkled in the heat pot, pour the leech silk of wine after vexed when to be smoldered into and stir, be yellow to leech silk surface, and take out rapidly when having special odor to overflow, the sieve wheat bran that defocuses cools, per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; Above-mentioned rhubarb, leech processed, pseudo-ginseng, Radix Codonopsis are mixed, fragmentation, separating twice is crossed 100 mesh sieves, or ultramicro grinding, get clean powder, put in the mixer with 75% ethanol (medicinal), mix above-mentioned clean powder, granulation, divide encapsulated in, 0.2 gram/grain, or get above-mentioned particle, add the moderate lubrication agent, such as talcum powder (medicinal), dolomol, control water content, be compressed into tablets, count 1000, every 0.2 gram.
Embodiment 3
Radix Codonopsis 100 grams, pseudo-ginseng 65 grams, leech 50 grams, rheum officinale 25 grams.Rheum officinale is mixed the clean rhubarb tablets of big or small stepping thoroughly according to the vinegar method for making with rice vinegar, the vexed profit to vinegar exhausted, and puts in the pot, when frying to surperficial little band focal spot by the temperature fire, cools after the taking-up, and per 100 gram rheum officinales are with rice vinegar 10 grams; Get water purification leech silk with yellow rice wine mix thoroughly, vexed profit, the wheat bran skin is sprinkled in the heat pot, pour the leech silk of wine after vexed when to be smoldered into and stir, be yellow to leech silk surface, and take out rapidly when having special odor to overflow, the sieve wheat bran that defocuses cools, per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; Above-mentioned rhubarb, leech processed, pseudo-ginseng, Radix Codonopsis are mixed fragmentation, separating twice, cross 100 mesh sieves, or ultramicro grinding, clean powder got, put in the mixer with 75% ethanol (medicinal), mix above-mentioned clean powder, granulation, in branch is encapsulated, 0.2 gram/grain, or get above-mentioned particle, add the moderate lubrication agent, such as talcum powder (medicinal), dolomol, the control water content is compressed into tablets, every 0.2 gram.
Embodiment 4
Radix Codonopsis 100 grams, pseudo-ginseng 50 grams, leech 60 grams, rheum officinale 25 grams.Rheum officinale is mixed the clean rhubarb tablets of big or small stepping thoroughly according to the vinegar method for making with rice vinegar, the vexed profit to vinegar exhausted, and puts in the pot, when frying to surperficial little band focal spot by the temperature fire, cools after the taking-up, and per 100 gram rheum officinales are with rice vinegar 10 grams; Get water purification leech silk with yellow rice wine mix thoroughly, vexed profit, the wheat bran skin is sprinkled in the heat pot, pour the leech silk of wine after vexed when to be smoldered into and stir, be yellow to leech silk surface, and take out rapidly when having special odor to overflow, the sieve wheat bran that defocuses cools, per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; Above-mentioned rhubarb, leech processed, pseudo-ginseng, Radix Codonopsis are mixed fragmentation, separating twice, cross 100 mesh sieves, or ultramicro grinding, clean powder got, put in the mixer with 75% ethanol (medicinal), mix above-mentioned clean powder, granulation, in branch is encapsulated, 0.2 gram/grain, or get above-mentioned particle, add the moderate lubrication agent, such as talcum powder (medicinal), dolomol, the control water content is compressed into tablets, every 0.2 gram.
Embodiment 5
Radix Codonopsis 100 grams, pseudo-ginseng 50 grams, leech 50 grams, rheum officinale 37.5 grams.Rheum officinale is mixed the clean rhubarb tablets of big or small stepping thoroughly according to the vinegar method for making with rice vinegar, the vexed profit to vinegar exhausted, and puts in the pot, when frying to surperficial little band focal spot by the temperature fire, cools after the taking-up, and per 100 gram rheum officinales are with rice vinegar 10 grams; Get water purification leech silk with yellow rice wine mix thoroughly, vexed profit, the wheat bran skin is sprinkled in the heat pot, pour the leech silk of wine after vexed when to be smoldered into and stir, be yellow to leech silk surface, and take out rapidly when having special odor to overflow, the sieve wheat bran that defocuses cools, per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; Above-mentioned rhubarb, leech processed, pseudo-ginseng, Radix Codonopsis are mixed fragmentation, separating twice, cross 100 mesh sieves, or ultramicro grinding, clean powder got, put in the mixer with 75% ethanol (medicinal), mix above-mentioned clean powder, granulation, in branch is encapsulated, 0.2 gram/grain, or get above-mentioned particle, add the moderate lubrication agent, such as talcum powder (medicinal), dolomol, the control water content is compressed into tablets, every 0.2 gram.
Claims (2)
1, a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease is characterized in that: be made up of Radix Codonopsis, Radix Notoginseng, Hirudo, Radix Et Rhizoma Rhei basically, weight proportion is: Radix Codonopsis 39%～53%, Radix Notoginseng 17%～29%, Hirudo 17%～27%, Radix Et Rhizoma Rhei 8%～18%.
2, a kind of method for preparing the described Chinese medicine preparation of claim 1, it is characterized in that: rheum officinale is pressed the vinegar method for making, and clean rhubarb tablets with the vexed profit of rice vinegar, is taken out rear warm fire and fries to surperficial little band focal spot, cools after the taking-up, and per 100 restrain rheum officinales rice vinegar 10 grams; Get water purification leech silk with yellow rice wine vexed profit, take out with the wheat bran skin of frying when smoldering and stir, take out when leech is yellow and have special odor to overflow, the sieve wheat bran that defocuses cools, and per 10 kilograms of leech are with 1 kilogram of yellow rice wine, 1 kilogram of wheat bran skin; With above-mentioned rhubarb, leech processed, Radix Codonopsis, panax mixed, broken, pulverize, sieve, get clean powder, stir with 75% medicinal alcohol, mix, preparing granular, or add again and be compressed into tablets after the water yield is controlled in the moderate lubrication agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310105678 CN1256112C (en) | 2003-11-19 | 2003-11-19 | Chinese traditional medicine preparation for treating cardiac and cerebral vascular diseases and its preparation process |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310105678 CN1256112C (en) | 2003-11-19 | 2003-11-19 | Chinese traditional medicine preparation for treating cardiac and cerebral vascular diseases and its preparation process |
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| Publication Number | Publication Date |
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| CN1543999A CN1543999A (en) | 2004-11-10 |
| CN1256112C true CN1256112C (en) | 2006-05-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200310105678 Expired - Fee Related CN1256112C (en) | 2003-11-19 | 2003-11-19 | Chinese traditional medicine preparation for treating cardiac and cerebral vascular diseases and its preparation process |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335241B (en) * | 2011-10-12 | 2013-06-05 | 郭聚忠 | Medicine for treating diabetes mellitus associated with hyperlipemia, and preparation method thereof |
| CN103127268B (en) * | 2013-03-14 | 2014-07-30 | 郭宏刚 | Oral beauty powder |
| CN104208609B (en) * | 2013-05-31 | 2017-11-24 | 朱乃香 | It is peaceful to pacify brain |
| CN103800482B (en) * | 2014-03-06 | 2015-08-12 | 李兵晖 | A kind of pharmaceutical composition for the treatment of myocardial ischemia and its preparation method and application |
| CN107213251B (en) * | 2017-06-08 | 2018-07-31 | 广州得效生物科技有限公司 | A kind of Chinese medicine composition and preparation method thereof prevented and/or treat cardiovascular and cerebrovascular disease |
| CN109481652A (en) * | 2017-09-12 | 2019-03-19 | 郑焕刚 | A kind of Chinese medicine and preparation method thereof for treating palpitation |
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