CN1253808A - Chinese medicine abortifacient - Google Patents
Chinese medicine abortifacient Download PDFInfo
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- CN1253808A CN1253808A CN 99113265 CN99113265A CN1253808A CN 1253808 A CN1253808 A CN 1253808A CN 99113265 CN99113265 CN 99113265 CN 99113265 A CN99113265 A CN 99113265A CN 1253808 A CN1253808 A CN 1253808A
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- ovum
- abortifacient
- sperm
- make
- human
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Abstract
The anticonceptive abortifacient preparation is made up by using the Chinese medicinal materials of bupleurum root, coumarona odorata, unripe bitter orange and polygala root and new geramine according to a certain proportion through a certain preparation process. The pharmacological and pharmacodynamic tests show that said invented product possesses the following action: 1. inactivating human sperm; 2. changing the zona pellucida activity of human ovum to make human sperm do not penetrate to resist combination of sperm with ovum, and 3. resisting implantation of ovum to early inactivate fertilized ovum to make it do not develop into embryon. At the same time it can kill several pathogenic microorganisms of diplococcus gonorrhoeae, etc., so that it can effectively prevent transmission of venereal diseases.
Description
The invention belongs to and a kind ofly be used to practise contraception and the Chinese medicine abortifacient of gynaecopathia such as induced abortion.
No matter traditional miscarriage induced labor way though have multiplely, is the doctor trained in Western medicine method, tcm methods, many pros and cons are respectively arranged, always allow the people have certain scruples, especially for the pregnancy period between 3 to 6 months, it is little that induced labor is disliked, big person is disliked in dilatation and curettage, and what good method is not a blank.Up to now, still there is not a kind of well-content fertility regulation technology that makes us in the worldwide.Since the seventies,, formed the upsurge of research drug induced abortion in the world along with the invention of gestation mifepristone (domestic goods name breath implied or Mifepristone).Because the pharmacology characteristics of this medicine itself are limit, only anti-very early pregnancy (pregnant 49 days with the former) and incomplete abortion often take place, also have five or six kinds of untoward reaction simultaneously, health ministry once hereinafter was used as some regulation to its making at home, WHO is also manufacturing experimently another kind of progesterone antagonist class contragestive agent ZK98.734 and is replacing it, but from formal clinical still far away.
For the shortcoming of improving prior art provides a kind of to the convenient and safe drug inducing labor of miscarrying reliably of equal energy of phase morning, noon and afternoon, simultaneously, be convenient to the especially common medical worker's use of basic unit of each stratum, avoid that tradition induced abortion often occurs do not miscarry, complication such as massive hemorrhage, or make it drop to minimum level, invented the Chinese medicine abortifacient.
The present invention is achieved in that
Adopt following prescription: Radix Bupleuri 20-30g, Herba Lysimachiae foenum-graeci 10-20g, Fructus Aurantii Immaturus 10-50g, Radix Polygalae 20-50g, and bromo geramine 10-20g.
Product pharmacological effect experiment confirm of the present invention has following effect:
1, deactivation human sperm.2, change the human oocyte zona pellucida activity, sperm can't be penetrated and influence smart ovum combination.3, stop implantation of ovum, make the early stage deactivation of cytula and can't develop into the embryo.This contraceptive liquid can kill the pathophorous source of disease microorganisms of diversity such as gonorrhea diplococcus simultaneously, thereby effectively prevents the generation of sexually transmitted disease (STD).Not only contraception also can be had an abortion.It is documented that there is the tens million of person-times of women service of need miscarrying every year in China, so social benefit and economic benefit are huge.
Theoretical and the argumentation of clinical experience according to medical science to writing out a prescription, Fructus Aurantii Immaturus is slightly cold for group's medicine, picric acid, goes into lung, spleen, stomach, liver, the large intestine Five Classics, and dispelling the stagnated QI removes the painful abdominal mass that disappears of amassing, reduce phlegm.Ancients' cloud: Fructus Aurantii Immaturus is specially let out excess of the stomach, convinces hard knot by patient analysis, thus the main middle part of gastric cavity to control blood system, it is full to treat the interventral reality of umbilicus, the expectorant addiction, dispel cut off the water, by dyspepsia, break blocked-up chest, relieving constipation is closed, non-this can not be also.If skin pruritus, because of hematocele stagnate in, can not nutrition flesh table, if diet do not think, can not fortune because of spleen pent-up, all get power that its hot hardship of loosing rushes down also.Gas medicine in this blood system, only this claims.Clearly " this crop smothering profit " cloud its: " removing mass has the gesture of acting speedily and vigorously, and rushing down expectorant has the wall of pushing away to fall the prestige of wall ".The modern Chinese medicine pharmacological research confirms: Fructus Aurantii Immaturus has significant excitation to tame rabbit uterus, makes uterine contraction strong, and tension force increases, and shrinks the rhythm and pace of moving things and strengthens, even straight the contraction occur.Authority thinks rabbit to the reaction of medicine, and is the most approaching with people's uterus in many aspects.The somebody isolates a kind of substance C irantin that stops gestation from the Fructus Aurantii Immaturus peel, it can also suppress the ovary activity of hyaluronidase on every side, and Pericarpium Citri Reticulatae Viride is a ministerial drug, and the toil temperature is returned liver, gallbladder, stomach warp.Soothing the liver dispelling the stagnated QI, the trifoliate orangeization that disappears stagnate, clear " this crop smothering profit " cloud " Pericarpium Citri Reticulatae Viride draws the branch of all medicines to the moon of fainting, and following diet is gone into lunar storehouse and broken the gas that stagnates, and the low more effect that heals is cut hard amassing, and it is good to heal down ".Radix Bupleuri is messenger drug, and bitter flat, resolving depression is soothing the liver, delivers and brings down a fever, and yang invigorating is clear." book on Chinese herbal medicine is looked for the truth " cloud: " Pericarpium Citri Reticulatae Viride, Radix Bupleuri makes for it " etc.All medicines share, and it is soothing the liver to play resolving depression altogether, declare smooth QI and blood, remove the painful abdominal mass blood stasis dispelling, and removing food stagnancy is capable to stagnate, the effect of induced abortion, thus make the uterus discharge embryo and appurtenance.
This medicine has changed the route of administration of Chinese medicine, makes medicine avoid the destruction of first pass effect and gastropore, reduces drug dose.Initiative combines technology such as traditional miscarriage, induced labor together, much month anemia of pregnant woman no matter, in uterine cavity, send into 5-10ml or put into suppository and membrane, just can remove uterine pregnancy at an easy rate, unnecessaryly divide pregnancy period morning, noon and afternoon artificially and take different birth-control measures.
Embodiments of the invention are provided below:
Example 1: get Radix Bupleuri 20g, zero Ling Xiang 10g, Fructus Aurantii Immaturus 10g, Radix Polygalae 10g, 1000ml gets distillate with azeotropic distillation method with water, adds bromo geramine 10ml and make water preparation after concentrating.
Example 2: get Radix Bupleuri 30g, zero Ling Xiang 10g, Fructus Aurantii Immaturus 15g, Radix Polygalae 15g, bromo geramine 12g add water steam boil after, add gelatin 20g after concentrating and make suppository.
Example 3: get Radix Bupleuri 20g, zero Ling Xiang 15g, Fructus Aurantii Immaturus 20g, Radix Polygalae 10g after bromo geramine 15g extracting in water becomes concentrating agents, adds the solubilized absorbing film and makes membrane.
Claims (1)
1, a kind ofly is used to practise contraception and the Chinese medicine abortifacient of gynaecopathia such as induced abortion; It is characterized in that, adopt following prescription: Radix Bupleuri 20-30g, Herba Lysimachiae foenum-graeci 10-20g, Fructus Aurantii Immaturus 10-50g, Radix Polygalae 20-50g, and bromo geramine 10-20g.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 99113265 CN1253808A (en) | 1999-09-29 | 1999-09-29 | Chinese medicine abortifacient |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 99113265 CN1253808A (en) | 1999-09-29 | 1999-09-29 | Chinese medicine abortifacient |
Publications (1)
Publication Number | Publication Date |
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CN1253808A true CN1253808A (en) | 2000-05-24 |
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ID=5276472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN 99113265 Pending CN1253808A (en) | 1999-09-29 | 1999-09-29 | Chinese medicine abortifacient |
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CN (1) | CN1253808A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1965912B (en) * | 2006-11-01 | 2010-09-08 | 山东省计划生育科学技术研究所 | Application of Chinese medicine polygala root as in-vitro spermaticide and method for preparing the medicament thereof |
CN102641401A (en) * | 2012-03-26 | 2012-08-22 | 刘星劼 | Suppository for reducing early pregnancy and reducing sequelae by administration through vagina |
-
1999
- 1999-09-29 CN CN 99113265 patent/CN1253808A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1965912B (en) * | 2006-11-01 | 2010-09-08 | 山东省计划生育科学技术研究所 | Application of Chinese medicine polygala root as in-vitro spermaticide and method for preparing the medicament thereof |
CN102641401A (en) * | 2012-03-26 | 2012-08-22 | 刘星劼 | Suppository for reducing early pregnancy and reducing sequelae by administration through vagina |
CN102641401B (en) * | 2012-03-26 | 2013-12-04 | 刘星劼 | Suppository for reducing early pregnancy and reducing sequelae by administration through vagina |
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