CN1249188A - Medicine for treating leukemia and its preparing process - Google Patents
Medicine for treating leukemia and its preparing process Download PDFInfo
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- CN1249188A CN1249188A CN98117988A CN98117988A CN1249188A CN 1249188 A CN1249188 A CN 1249188A CN 98117988 A CN98117988 A CN 98117988A CN 98117988 A CN98117988 A CN 98117988A CN 1249188 A CN1249188 A CN 1249188A
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Abstract
A medicine for treating leukemia is prepared from 6 Chinese-medicinal materials including natural ox gallstone, natural musk, realgar, phabitis seed, etc through proportioning, pulverizing and pilling. It is taken along with mint water. Its advantages are distinct curative effect and unique preparing process.
Description
The present invention relates to the leukemic medicine of a kind of treatment, specifically a kind of is the leukemic Chinese patent medicine of treatment that raw material is made with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Leukemia is a kind of difficult diseases of clear and definite its pathogenic factor not as yet at present, and the title of leukemia is arranged.Specifically, leukemia is a kind of disease of blood system, mainly is leukocyte and precursory cell thereof paraplasm in blood tissues, can soak into each tissue and internal organs, produces various symptoms, and the leukocyte of surrounding hemogram also has the change of quality and quantity.Therefore, leukemia is a kind of neoplasm disease of general.It falls ill anxious, changes soon, and mortality rate is high, seriously the harm person people's physical and mental health.So be one of core of present motherland medical research.
Treatment for this disease, the about treatment means in west both at home and abroad more at present adopts " killing and wounding therapy ", " bone marrow transplantation therapy ", " antilepsis " these three kinds of methods to treat, these three kinds of methods all exist a common characteristic to be, intravital good bad cell is killed and wounded simultaneously, weakened the immunocompetence of self greatly, side effect to human body is very big, poor slightly just being difficult to of body constitution born, patient also is very painful in the therapeutic process, moreover the alleviation of symptom is temporary transient usually, and medical expense is very expensive.Use theory of Chinese medical science and method at present and also still do not have comparatively ideal Therapeutic Method.
The object of the present invention is to provide a kind of leukocytic index that reduces, increase erythrocytic numerical value, eliminate the medicine of the treatment acute and chronic leukemia of juvenile cell.This medicine instant effect, toxic and side effects is low, and expense is cheap, taking convenience, patient's misery is little, easily accepts.
Another object of the present invention provides the preparation method of this leukemia treating agent.
Solution of the present invention is based on the understanding of motherland's medical science to leukemic mechanism, filters out from motherland medicine treasure-house that heat-clearing and toxic substances removing, the cool heart are calmed the frightened, eliminated phlegm for resuscitation, the natural drug prescription of spleen invigorating hemopoietic forms.Think that leukemic pathogeny is volt in the evil poison, cloudy smart internal injury, the bone marrow of burning has destroyed hematopoietic function, makes due to its hemopoietic function disorder.
Medicine of the present invention is owing to following component is made: (consumption is a weight portion)
Natural Calculus Bovis 6-15 natural Moschus 6-12 Realgar 5-10
Concretio Silicea Bambusae 12-30 Semen Pharbitidis 12-30 Fagopyrum esculentum Moench 10-20
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
Natural Calculus Bovis 6 natural Moschuss 6 Realgars 6
Concretio Silicea Bambusae 6 Semen Pharbitidiss 3 Fagopyrum esculentum Moenchs 15
Calculus Bovis in the medicine of the present invention, conscience two warps are gone in the cold of acrid-sweet flavor gas, the sharp liver and gall that clear away heart-fire, the will of composing oneself, peace soul are arranged, the merit of the sharp expectorant of heat clearing away." assorted opinion " cloud: " this thing is gone into liver and is controlled disease located in tendon, and all apoplexy are gone into dirty person, must use the agent of Calculus Bovis, Realgar, Moschus, the person that goes into bone marrow, and skin goes out with air inducing thoroughly; If internal organs and blood vessels person among the wind, then anti-air inducing heresy is gone into bone marrow ".And the cloudy just smart internal injury of leukemia, the bone marrow interior-heat.So-called heat in the marrow has destroyed hematopoietic function, so the treatment leukemia must first be used Calculus Bovis, can middle disease be monarch drug.Ambrosiac acrid in the mouth temperature is gone into conscience two warps, and having has one's ideas straightened out keeps away dirtyly, and promoting blood circulation to remove blood stasis expedites the emergence of down the effect of tire, with the Calculus Bovis compatibility, can increase the heat-clearing and toxic substances removing conduct of Calculus Bovis, is ministerial drug.Realgar, acrid in the mouth temperature is gone into liver stomach two warps, separates sore, insecticidal action.According to " herbal classic " cloud: main cold and heat scrofula, the dead flesh of cellulitis hemorrhoid kills hundred insect poison ".Realgar includes arsenic sulfide, use with malicious merit poison, strengthen the antipyretic and antidote functions of its Calculus Bovis.The Concretio Silicea Bambusae sweet in the mouth is cold, goes into conscience two warps, has clear heat and eliminate phlegm, the effect of cool heart arresting convulsion.According to the essentials of Matea Medica cloud: " cool heart channel goes wind heat, sharp key eliminating phlegm, Liang Xin town liver makes eye bright ", the smart internal injury of the leukemic the moon of direct attack, outside not only heat in the marrow, and heat was tending towards, disease was seen the disease of hyperpyrexia coma, got its cool heart arresting convulsion, the effect that heat clearing away is stopped burning.Semen Pharbitidis, bitter in the mouth gas is cold, goes into liver stomach large intestine three warps, has and rushes down down long-pending merit.Fang Zhongyong this and Concretio Silicea Bambusae are compatible, strengthen the wind heat clearing away effect that removes of its Calculus Bovis, and invisible pathogenic heat is gone out from stool, remove its dryness accumulated in the stomach and intestine, are adjuvant drug.
Medicine of the present invention can be made into pill, and concrete grammar is as follows:
With each flavor medicated powder broken after, add Fagopyrum esculentum Moench and suitable quantity of water and mix the back and get final product with the pellet processing machine pill.
Medicine batter of the present invention is nine, gets the property of its essence derived from food, fills its QI of the spleen and stomach, transfers the source of its QI and blood as a means of hemopoietic.
And medicine of the present invention needs to fry in shallow oil the water delivery service pill with Herba Menthae.Record according to " book on Chinese herbal medicine is looked for the truth ": " mint smell is hot cool, and merit is specially gone into liver and lung, so book all carries, suffering can be dispersed, and in the headache wind syndrome of head, fever with chills is then suitable: the heat clearing away of cool energy, and in throat, ability to speak skin ulcer scabies, fever (of children) accompanied by fear hectic fever due to YIN-deficiency epistaxis is then wonderful ".The Zhi Qire with cold, all blood go out and can control, and to go into bone marrow be messenger drug and draw all medicines.
For showing medicine of the present invention to leukemic therapeutic effect, the leukemia case of system of the present invention selection all kinds and all ages and classes, sex uses medicine of the present invention to treat, and be 7 days a course of treatment.
Instructions of taking: every day secondary, each ball, every ball 1 gram with 30 restrains Herba Menthaes when taking at every turn and fries in shallow oil water delivery service.Its therapeutic effect can be added up referring to table 1 clinical data.
Alleviate: 1. outer bucket phenomenon is normal, the no abnormal cell of bone marrow (juvenile cell, germinal cell);
2. recover operate as normal in 3 years, do not recur.
Promptly be eased two courses of treatment.
Part is alleviated: 1. outer bucket phenomenon is eliminated unstable, the time low when high;
2. germinal cell still appears in bone marrow examination, surpasses normal value, and self symptom takes a turn for the better.
Reaching part in 3 years alleviates.
Table 1 clinical data statistics
Type of leukemia | Case load (people) | Alleviate (people) | Part is alleviated (people) | Dead (people) | |
The BM form leukemia | Acute chronic | ????11 ????38 ????26 ????13 | ????5 ????26 ????18 ????5 | ????2 ????7 ????6 ????4 | ????2 ????2 ????4 ????7 |
Lymphocytic leukemia | Acute chronic |
By statistics, what produce effects was arranged is 61%, and effective percentage is 21%, and inefficiency is 18%.
By above-mentioned clinical data as seen, medicine of the present invention can be to a great extent the symptom of palliating leukemia quickly, eliminate outer bucket phenomenon, kill abnormal cell.Taking convenience, patient easily accepts, and side effect is little, and expense is low, instant effect, most of being difficult for recurs.
Embodiment
Take by weighing raw material (kilogram) by following proportioning:
Natural Calculus Bovis 6 natural Moschuss 6 Realgars 6
Concretio Silicea Bambusae 6 Semen Pharbitidiss 3 Fagopyrum esculentum Moenchs 15
Preparation method was for to pulverize 800 mesh sieves with natural Calculus Bovis, natural Moschus, Realgar, Concretio Silicea Bambusae and Semen Pharbitidis, added Fagopyrum esculentum Moench and an amount of distilled water and made ball about 1 gram with pellet processing machine.
Model case:
1. Zheng, man, 44 years old, Liaoning Province's Lingyuan County four cadres of people's commune of pipe battalion.In the spring in 1980,
Because of eyes are fuzzy, vision weakens, and both legs are ached, pain in chest and hypochondrium, and inappetence goes to court
The regional the People's Hospital of sun checks, is reported as every cubic millimeter 370,000 of leukocyte, and erythrocyte is whenever upright
Square millimeter 1,040,000, bone marrow aspiration, juvenile cell are seen more, 9 centimeters of spleen enlargements, whole body
The blood stasis point and the speckle that are dispersed in are arranged, be diagnosed as " chronic BM form leukemia ".Go to immediately Beijing to live
Section treatment in 307 hospitals of PLA, take Western medicine " the new cash in Changchun ", " Maryland ", " Ah
The luxuriant glycosides of sugar " etc. the medicine chemotherapy, symptom respite, but leukocyte is always more than 20,000,
Juvenile cell in the bone marrow fails to disappear always.I institute treat former rice upon somebody's introduction.Take this
The invention medicine, every day twice, each 1 gram is fried in shallow oil water delivery service with Herba Menthae 30 grams.Take medicine two
After the course of treatment (two weeks) positive effect is arranged promptly, body constitution is recovered, 8 jin of weight increase, hemogram and
Bone marrow examination is all within normal range.Continue to take medicine after two courses of treatment, on inspection leukocyte
Every cubic millimeter 8000, every cubic millimeter 4,400,000 of erythrocyte, hematochrome 12.5 grams, bone marrow
Check and do not see juvenile cell and abnormal phenomena.Soon, the patient can go to work work.
2. Pan, man, 46 years old, the workman of Henan Province Anyang Press.In March, 1980, conscious body
The body paralysis is a cup too low, and the right side of body is pain down, and the preceding the People's Hospital, Anyang that goes checks, finds liver
The dirty enlargement side of body is two fingers down, 10 centimeters of spleen enlargements.Hemogram checking is reported as leukocyte 27.5
Ten thousand, the acidophilia 2%, basophilia 8%, and juvenile cell 29% is diagnosed as chronic granulocytic
Leukemia changes Henan institute of traditional Chinese medicine subsequently over to, lives internal medicine No. one, imitates through taking Chinese medicine and chemotherapy
Fruit is all undesirable.After change my institute over to, take medicine of the present invention, every day secondary, each one,
Fry in shallow oil water delivery service with Herba Menthae 30 grams.Conscious spirit takes a turn for the better after taking medicine 10 days, and temperature is burnt and moved back, and the side of body is not
Painful.After be in again took medicine 10 days after, the state of an illness is clearly better, hepatosplenomegaly disappears, diet increases
Add (can obey 4-6 two staple foods for every), body constitution is recovered, and through laboratory report, leukocyte is whenever upright
Square millimeter 8600, every cubic millimeter 5,500,000 of erythrocyte, hematochrome 12.5 grams, juvenile cell
Do not find.Body weight is increased to 128 jin for 100 jin by the less than before taking medicine.The work of having gone to work.
3. Zhu, 9 years old, student, regional peaceful and comfortable people from people's commune of sun that fall of Henan Province.In March, 1979,
Fever, inappetence, myasthenia of limbs burns the back and perspires, night night sweat, at once by with malaria
Treatment is invalid.Go to Luo Yang city the People's Hospital's fluoroscopic examination again, finding has tuberculose focus, takes antituberculosis drugs thing a period of time, and symptom does not disappear.Went to Henan Prov. People's Hospital to do bone marrow examination August 15, be diagnosed as acute lymphatic leukemia, be in hospital after chemotherapy symptom respite.After change the treatment of my institute over to, disease sees that spirit is general, 38.7 ° of body temperature, variable interval in afternoon fever, skelalgia is violent, maximum duration can reach 10 minutes during pain, spontaneous remission, pulse condition is counted accurately, the tongue fur red drop, cervical region oxter, femoribus internus and groin have the lymphadenectasis of Semen Viciae fabae.Though it is through chemotherapy, symptom is alleviated for the moment, does not solve in the pyretic toxicity and accumulates, the principal contradiction of cloudy smart internal injury.Through taking medicine of the present invention after 15 days, all right on inspection, the children drench and lymphoid propagation situation all in normal range, the phenomenon that has a pain in the leg, has a fever, also complete obiteration, lymphadenectasis does not exist.After take again medicine of the present invention 20 big after, all are normal, physically well develop, and get well.
Claims (6)
1. the leukemic medicine of treatment is characterized in that it is the medicament of being made by the following weight proportion raw material
Natural Calculus Bovis 6-15 natural Moschus 6-12 Realgar 5-10
Concretio Silicea Bambusae 12-30 Semen Pharbitidis 12-30 Fagopyrum esculentum Moench 10-20
2. treatment leukemia according to claim 1, wherein the weight proportion of each raw material is
Natural Calculus Bovis 6 natural Moschuss 6 Realgars 6
Concretio Silicea Bambusae 6 Semen Pharbitidiss 3 Fagopyrum esculentum Moenchs 15
3. the leukemic medicine of treatment according to claim 1 and 2 is characterized in that said medicament is a said dosage form on any pharmaceutics.
4. the leukemic medicine of treatment according to claim 3 is characterized in that said medicament is a pill.
5. according to the preparation method of the said treatment leukemia medicament of claim 4, it is characterized in that getting and respectively distinguish the flavor of after raw material pulverizing sieves, make pill after adding Fagopyrum esculentum Moench and water.
6. the preparation method of the leukemic medicine of treatment according to claim 5, the weight that it is characterized in that said pill are 1 gram.
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CN98117988A CN1105567C (en) | 1998-09-29 | 1998-09-29 | Medicine for treating leukemia and its preparing process |
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CN98117988A CN1105567C (en) | 1998-09-29 | 1998-09-29 | Medicine for treating leukemia and its preparing process |
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CN1249188A true CN1249188A (en) | 2000-04-05 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101590103B (en) * | 2008-05-27 | 2012-07-18 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine combination for treating leukemia and preparation method thereof |
CN101590192B (en) * | 2008-05-27 | 2012-08-08 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine combination for treating leukemia and preparation method thereof |
CN101590092B (en) * | 2008-05-27 | 2013-01-30 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine combination for treating leukemia and preparation method thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1048873C (en) * | 1993-04-02 | 2000-02-02 | 包鸿廷 | Traditional herb medicine for treating leukaemia |
CN1118262A (en) * | 1994-09-08 | 1996-03-13 | 刘凤江 | Compounded composition for cancers |
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1998
- 1998-09-29 CN CN98117988A patent/CN1105567C/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101590103B (en) * | 2008-05-27 | 2012-07-18 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine combination for treating leukemia and preparation method thereof |
CN101590192B (en) * | 2008-05-27 | 2012-08-08 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine combination for treating leukemia and preparation method thereof |
CN101590092B (en) * | 2008-05-27 | 2013-01-30 | 北京因科瑞斯医药科技有限公司 | Traditional Chinese medicine combination for treating leukemia and preparation method thereof |
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