CN1242221A - Active royal jelly sucked tablet and method for preparing same - Google Patents
Active royal jelly sucked tablet and method for preparing same Download PDFInfo
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- CN1242221A CN1242221A CN99108046A CN99108046A CN1242221A CN 1242221 A CN1242221 A CN 1242221A CN 99108046 A CN99108046 A CN 99108046A CN 99108046 A CN99108046 A CN 99108046A CN 1242221 A CN1242221 A CN 1242221A
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- lyophilized powder
- lac regis
- regis apis
- royal jelly
- sugar
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Abstract
The invented product contains freeze-dried rogal jelly powder, freeze-dried ginseng fruit powder, sugar, mannitol, dextrin, glycine and citric acid. The prepn. method is as follows: first prepare the above-mentioned two freeze-dried powders, crush sugar, mannitol, glycine and pass 80-120 mesh sieve, dissolve citric acid in water, mix all the above-mentioned materials and make into tablets. The present invention is a good health-care product for the aged and weak persons after sickness.
Description
The present invention relates to nutrient and healthcare products, particularly a kind of active royal jelly sucked tablet and preparation method thereof.
China's apiculture is with a long history, and among the people also early have application to bee products.The legend of " the honeybee treasured is controlled all kinds of diseases and ailments " is arranged in the Yunnan Province of China ethnic groups, and so-called " honeybee treasured " promptly refers to Lac regis apis.The functional study to Lac regis apis abroad started from for 20th century, nineteen thirty-nine H..L.Heyl etc. has proposed the report of the short gonad effect of royal jelly, be early to set forth the research of royal jelly to the body effect, after, the scientist of various countries has carried out extensive studies to physiology, pharmacology and the clinical effect of Lac regis apis, many reports are come out one after another, and the international community's bee-keeping associating group of raising bees is also set up Apis therapy special interest group specially.The fifties, critically ill when crouching at bed over the Pope Pi Ao 12 of eighty-year-old disease, take after the message of rehabilitation spreads out of miraculously behind the Lac regis apis the from then on fashionable whole world of Lac regis apis.
For a long time, people come from the observation of people to the bee colony living habit to the understanding of Lac regis apis.Queen bee and worker bee all are to be formed by development of fertilized ova, and changing in quality from germ cell is adult, and queen bee only need be with 16 days, and worker bee then needs 21 days.The height of queen bee is longer 1 times than worker bee, and the weight ratio worker bee weighs 2 times, and queen bee around the clock lays eggs, and the ovum quantity of giving birth to every day can reach 2000 pieces, is equivalent to from heavy sensation of the whole body.The queen bee life-span is 3-5, and worker bee can only live 30-40 days, at most only 8 months, all these differences of queen bee and worker bee, all relevant with the food that they are eaten, from the larva to the adult and after the several years, queen bee is a food with royal jelly always, and worker bee can only be a food with pollen, Mel.That is to say, be because this material of Lac regis apis has been determined queen bee " imperiality ", also determined simultaneously the subordinate status of worker bee, this owing to the food difference causes big life difference phenomenon like this between the individuality of the same race, actually rare at biosphere, this is enough to illustrate the physiological function of Lac regis apis and its peculiar part.
See on one's body Apis, royal jelly has powerful life-saving effect, and the someone thinks that royal jelly contains two kinds of globulin, and it is a kind of composition that prevents aging, increases Abwehrkraft des Koepers, the scholar who also has thinks that royal jelly makes people's life-prolonging factor, is pantothenic acid and many pyrroles alcohol (vitamin B
6) in action.The theory that at present understanding of aging is had three aspects: free radical theory, the neuroendocrinology immunological theory of mediating a settlement.According to these three theories; China Military Medical Science Institute carries out the experimentation of slow down aging with the Lac regis apis of dew aquatic foods; the result shows that pure fresh royal jelly has protective effect to superoxide dismutase (SOD), can exempt human body and be subjected to the damage of free radical and can remove free radical.Pure fresh royal jelly can produce inhibitory action to monoamine oxidase-B (MAO-B) in rat and the mice body, can alleviate that youngster's naphthol amine level descends and the infringement that causes the body biochemical process.Dew fresh royal jelly can make Aged Mice spleen antibody form, and cell number is recovered, at external increase vitamin A inducing mouse lymphopoiesis.These three evidence Lac regis apis have tangible many-sided defying age mechanism and effect.
Good health and a long life are for of all times people is yearned for.Eliminate disease and prolong life, attracting countless people making great efforts discussion.Develop into the end of the century science and technology this century and obtained unprecedented great development, the antibiotic appearance in particularly medical aspect, the production of synthetic medicine is for human treating disease, life lengthening have all been obtained huge achievement.But along with being extensive use of of chemical drugs, the side effect and the harm that bring to health of people also are quite serious.Therefore, back to nature, the food of seeking to eliminate disease and prolong life from nature becomes current medical science worker's the starting point.It is found that in long-term practice Lac regis apis is exactly wherein the most valued a kind of senior nutrition and the natural tonic that strengthens body immunity, eliminates disease and prolong life.In the at present commercially available royal jelly goods, in the majority with the oral liquid of royal jelly dosage form, but when daily taking, brought many troubles to people.For example: preservation condition requires high: pure Lac regis apis will be stored in freezer compartment of refrigerator, keeping its activity, and this Lac regis apis mouthfeel bitterness, be difficult to eat; Make the Lac regis apis of oral liquid, wherein almost do not have active ingredient, nutrition content is very little in the finished product after the dilution, and vial cracky and the accident that meets accident, make carry, edible all inconvenience.
The purpose of this invention is to provide a kind of nutritious, biological activity is high, can building body, slow down aging and preservation, carry, edible all active royal jelly sucked tablets easily.
Another object of the present invention provides a kind of preparation method of above-mentioned active royal jelly sucked tablet.
Contain Lac regis apis lyophilized powder, Herba Herminii lyophilized powder, sugar, mannitol, dextrin, glycine and citric acid in the active royal jelly sucked tablet of the present invention, the parts by weight proportioning of wherein said each composition is:
Lac regis apis lyophilized powder 50-200 part Icing Sugar 180-280 part
Mannitol 130-230 part dextrin 80-120 part
Glycine 60-100 part citric acid 15-30 part
Herba Herminii lyophilized powder 10-60 part
Described sugar is preferably used white sugar; Described water can be distilled water, mineral water, pure water, preferably uses distilled water.
Lac regis apis also claims Lac regis apis, Lac regis apis.Lac regis apis is the lingual gland (hypopharyngeal gland) and the common excretory mixture of mandibular gland of children's worker bee head in age, is a kind of milky or light yellow, and sour and astringent, acid, little sweet and have a slurry of special aroma is arranged.The chemical analysis of Lac regis apis is very complicated, contains extremely abundant biological activity nutrition.Contain three classes and the identical highly active protein class material of protein in the blood of human body in the Lac regis apis, that is: para-insulin, active polypeptide and r globulin, they are having crucial effect aspect body metabolism and the raising immunity regulating.Kind of free amino acid surplus also containing 30 in the Lac regis apis wherein has eight kinds of human bodies not synthesize, and must absorb in food.Lac regis apis is the abundantest food of vitamin content, and vitamin B group is particularly abundant, and the human body vitamin of easy shortage, all contains in the Lac regis apis.Particularly acetic acid choline content in Lac regis apis is the hat of all wholefoods, and it has the important physical effect as a kind of transmitter substance.Kind of mineral surplus also containing 10 in the Lac regis apis, wherein ferrum, calcium are the indispensable elements of hemopoietic.
In addition, also contain nucleic acid and nucleotide in the Lac regis apis, biological butterfly wing element, PHOSPHATIDYL ETHANOLAMINE and micro-hormone, and 3% mysterious unknown material, they are elite of high activity composition in the royal jelly.
Because to be the Apis worker bee edible for Lac regis apis through the Mel of brew with through the pollen of natural fermentation, therefrom absorb nourishment and energy and synthetic with the nutrient that absorbs, therefore, in fact the raw material of synthetic royal jelly derives from pollen and nectar.
The biological function of Lac regis apis and higher biological activity make it show magical effect, for its application provides wide prospect.The modern medical service practice shows that Lac regis apis can promote the metabolism of human body, and the cell regeneration ability is strengthened, and has in time filled up old and feeble cell.It can also promote protein synthesis effectively, improves the stress ability of body, as high temperature, high and cold, anoxia, extremely tired, lonizing radiation infringement etc., it can also increase erythrocyte and hematoblastic quantity, blood fat and blood pressure is tending towards normally, and these all are to prevent old and feeble mechanism of action.
Test with Lac regis apis, find that it can make interior lipid oxide (LPO) the myocardial cell fat brown stain of animal body obviously descend, this illustrates that it has the effect of antioxidant, and can delay the formation of free radical, does the fruit bat experiment with it simultaneously, then obviously can prolong fruit bat life.
The preparation method of active royal jelly sucked tablet of the present invention comprises makes lyophilized powder with Lac regis apis, the Herba Herminii extracting juice is made lyophilized powder, sugar, mannitol, glycine were pulverized the 80-120 mesh sieve, be stirred to moltenly entirely with citric acid is soluble in water, all raw material mix homogeneously were made tablet.
Wherein, the process that described Lac regis apis is made lyophilized powder comprises: with adding water in the fresh Lac regis apis, stir, making its concentration is 10-15%, in 40 ￣-50 ℃ temperature range, according to the Lac regis apis freeze-drying curve, carry out 40-50 hour lyophilization, promptly get Lac regis apis lyophilized powder.
Lyophilization is the preferred approach that at present serosity is become the dry thing of powdery, Lac regis apis lyophilized powder is exactly with fresh royal jelly quick freezing at low temperatures, make the hydrone that the freezes process without water from ice, aquation gas then under suitable vacuum condition, directly distillation is the aqueous vapor effusion.Freeze dried royal jelly activity is stable, preserves 3 years mass conservations, and Lac regis apis lyophilized powder has and the new identical color of fresh royal jelly, and has kept the original activity active ingredient well, and the clinical effectiveness proof has consistent curative effect with fresh royal jelly.
The process that described Herba Herminii extracting juice is made lyophilized powder comprises: wear into slurry after fresh Herba Herminii is cleaned, sterilizes, filter, the extracting juice waste, juice is placed freeze dryer, in 38-40 hour, according to freeze-drying curve, under 43 ￣-45 ℃ temperature, 30-35pa pressure, carry out lyophilization, promptly get the Herba Herminii lyophilized powder.
Active royal jelly sucked tablet of the present invention, it is all convenient to preserve, carry, eat, and can slowly dissolve by buccal in mouth, increased the absorption of oral mucosa to its active ingredient, simultaneously mouthfeel is pure, enjoys endless aftertastes, and is the climacteric men and women and the health-care good product of weakling and middle-aged and elderly people slow down aging after being ill.In the prescription except that Lac regis apis lyophilized powder, also contain Icing Sugar, mannitol, dextrin, glycine and citric acid, wherein Icing Sugar, mannitol are as main excipient, have sweet taste, in the buccal fusion process of oral cavity, solution is the refrigerant sense that has low in calories, be applicable to that mid-aged population is edible, the slice, thin piece any surface finish of making, attractive in appearance, flavor is good; Glycine and citric acid also play the effect of reconciling local flavor as antioxidant and antibacterial the time in prescription; Selecting for use of dextrin is in order to increase the hardness of tablet, and the tool adhesive effect.
Further describe the present invention below in conjunction with drawings and Examples
Accompanying drawing 1 is the freeze-drying curve of Lac regis apis.
Accompanying drawing 2 is the freeze-drying curve of Herba Herminii.
Embodiment
Contain Lac regis apis lyophilized powder, Herba Herminii lyophilized powder, white sugar, mannitol, dextrin, glycine and citric acid in the active royal jelly sucked tablet of the present invention, the parts by weight proportioning of wherein said each composition is:
230 parts of 50 portions of white sugars of Lac regis apis lyophilized powder
100 parts in 180 parts of dextrin of mannitol
20 parts of 80 parts of citric acids of glycine
40 parts of Herba Herminii lyophilized powders
The preparation method of above-mentioned active royal jelly sucked tablet is that Lac regis apis is made lyophilized powder, the Herba Herminii extracting juice is made lyophilized powder, sugar, mannitol, glycine were pulverized 100 mesh sieves, citric acid is dissolved in is stirred to moltenly entirely in the distilled water, all raw material mix homogeneously were made tablet.
Wherein, the process that described Lac regis apis is made lyophilized powder comprises: with adding water in the fresh Lac regis apis, stir, making its concentration is 15%, in 40 ￣-50 ℃ temperature range, according to accompanying drawing 1 Lac regis apis freeze-drying curve, carry out 40-50 hour lyophilization, promptly get Lac regis apis lyophilized powder.
The process that described Herba Herminii extracting juice is made lyophilized powder comprises: wear into slurry after fresh Herba Herminii is cleaned, sterilizes, filter, the extracting juice waste, juice is placed freeze dryer, in 38-40 hour, according to accompanying drawing 2 freeze-drying curves, under 43 ￣-45 ℃ temperature, 30-35pa pressure, carry out lyophilization, promptly get the Herba Herminii lyophilized powder.
During preparation, divide following step to carry out:
A, that white sugar, mannitol, glycine were pulverized 100 mesh sieves was standby.
B, pin citric acid be dissolved in be stirred in the distilled water complete molten standby.
C, all raw materials are placed mixer, mix homogeneously adds the above-mentioned aqueous solution for preparing and makes suitable soft material, granulates with 14 order stainless steel meshs.
D, wet granular is placed ebullated dryer low-temperature boiling drying at 32-35 ℃, control moisture content is about 2%.
E, dry good granule add the magnesium stearate granulate.
F, outward appearance, inherent quality requirement tabletting by buccal tablet.
G, qualified buccal tablet are on inspection obturaged by 6 of every plates with two aluminium foil packaging materials, stamp lot number.
H, irradiation cobalt-60 sterilization of packing back, exposure dose is 5.7kgy.
Product behind i, the irradiation is tested by the outgoing standard, puts in storage after the assay was approved, and shady and cool dry place stores.
Claims (7)
1, a kind of active royal jelly sucked tablet is characterized in that containing Lac regis apis lyophilized powder, Herba Herminii lyophilized powder, sugar, mannitol, dextrin, glycine and citric acid.
2, active royal jelly sucked tablet as claimed in claim 1 is characterized in that the parts by weight proportioning of wherein said each composition is:
Lac regis apis lyophilized powder 50-200 part Icing Sugar 180-280 part
Mannitol 130-230 part dextrin 80-120 part
Glycine 60-100 part citric acid 15-30 part
Herba Herminii lyophilized powder 10-60 part
3, active royal jelly sucked tablet as claimed in claim 1 is characterized in that described sugar preferably uses white sugar.
4, active royal jelly sucked tablet as claimed in claim 1 is characterized in that described water is distilled water, mineral water or pure water, preferably uses distilled water.
5, as the preparation method of the described active royal jelly sucked tablet of claim 1-4, it is characterized in that comprising Lac regis apis is made lyophilized powder, the Herba Herminii extracting juice is made lyophilized powder, sugar, mannitol, glycine were pulverized the 80-120 mesh sieve, be stirred to moltenly entirely with citric acid is soluble in water, all raw material mix homogeneously are made tablet.
6, preparation method as claimed in claim 5, it is characterized in that described Lac regis apis makes the process of lyophilized powder and comprise: will add water in the fresh Lac regis apis, stir, making its concentration is 10-15%, in 40 ￣-50 ℃ temperature range, according to the Lac regis apis freeze-drying curve, carry out 40-50 hour lyophilization, promptly get Lac regis apis lyophilized powder.
7, preparation method as claimed in claim 5, it is characterized in that the process that described Herba Herminii extracting juice is made lyophilized powder comprises: wear into slurry after fresh Herba Herminii is cleaned, sterilizes, filter, the extracting juice waste, juice is placed freeze dryer, in 38-40 hour, according to freeze-drying curve, under 43 ￣-45 ℃ temperature, 30-35pa pressure, carry out lyophilization, promptly get the Herba Herminii lyophilized powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99108046A CN1096864C (en) | 1999-06-11 | 1999-06-11 | Active royal jelly sucked tablet and method for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99108046A CN1096864C (en) | 1999-06-11 | 1999-06-11 | Active royal jelly sucked tablet and method for preparing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1242221A true CN1242221A (en) | 2000-01-26 |
| CN1096864C CN1096864C (en) | 2002-12-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99108046A Expired - Fee Related CN1096864C (en) | 1999-06-11 | 1999-06-11 | Active royal jelly sucked tablet and method for preparing same |
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| Country | Link |
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| CN (1) | CN1096864C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104544041A (en) * | 2013-10-24 | 2015-04-29 | 格尔木源鑫堂生物科技有限公司 | Plateau royal jelly berry buccal tablet and preparation method thereof |
| CN104623272A (en) * | 2013-11-12 | 2015-05-20 | 呼和浩特市通瑞科技有限责任公司 | Preparation method of compound traditional Chinese medicine containing royal jelly |
| CN104886430A (en) * | 2015-06-09 | 2015-09-09 | 江苏日高蜂产品有限公司 | Royal jelly freeze-dried buccal tablet and preparation technology thereof |
| CN104957605A (en) * | 2015-06-03 | 2015-10-07 | 通化百泉保健食品有限公司 | Ginseng and Chinese wolfberry fruit compound health-care buccal tablet and preparation method thereof |
| CN105455082A (en) * | 2015-12-15 | 2016-04-06 | 北京农科亿健蜂产品研究院 | Preparation method of three-treasure tablet |
| CN106360542A (en) * | 2016-08-26 | 2017-02-01 | 湖北新阳蜂业有限公司 | Royal jelly buccal tablets and preparation method thereof |
| CN110547420A (en) * | 2018-05-30 | 2019-12-10 | 福州大学 | Royal jelly enzyme buccal tablet and preparation method thereof |
-
1999
- 1999-06-11 CN CN99108046A patent/CN1096864C/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104544041A (en) * | 2013-10-24 | 2015-04-29 | 格尔木源鑫堂生物科技有限公司 | Plateau royal jelly berry buccal tablet and preparation method thereof |
| CN104623272A (en) * | 2013-11-12 | 2015-05-20 | 呼和浩特市通瑞科技有限责任公司 | Preparation method of compound traditional Chinese medicine containing royal jelly |
| CN104957605A (en) * | 2015-06-03 | 2015-10-07 | 通化百泉保健食品有限公司 | Ginseng and Chinese wolfberry fruit compound health-care buccal tablet and preparation method thereof |
| CN104886430A (en) * | 2015-06-09 | 2015-09-09 | 江苏日高蜂产品有限公司 | Royal jelly freeze-dried buccal tablet and preparation technology thereof |
| CN105455082A (en) * | 2015-12-15 | 2016-04-06 | 北京农科亿健蜂产品研究院 | Preparation method of three-treasure tablet |
| CN106360542A (en) * | 2016-08-26 | 2017-02-01 | 湖北新阳蜂业有限公司 | Royal jelly buccal tablets and preparation method thereof |
| CN110547420A (en) * | 2018-05-30 | 2019-12-10 | 福州大学 | Royal jelly enzyme buccal tablet and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1096864C (en) | 2002-12-25 |
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