CN1239207C - 一种人工生物套管及其制造方法 - Google Patents
一种人工生物套管及其制造方法 Download PDFInfo
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- CN1239207C CN1239207C CN 01134542 CN01134542A CN1239207C CN 1239207 C CN1239207 C CN 1239207C CN 01134542 CN01134542 CN 01134542 CN 01134542 A CN01134542 A CN 01134542A CN 1239207 C CN1239207 C CN 1239207C
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- chitosan
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- artificial biological
- calcium alginate
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Abstract
Description
实施例4 | 实施例5 | 实施例6 | |
纺丝原液 | |||
海藻酸钠 | |||
分子量(万) | 22 | 39 | 61 |
浓度(%) | 10 | 6 | 3 |
压力(MPa) | 0.3 | 0.8 | 0.5 |
神经生长因子(%) | 1 | 10 | 15 |
(相对于海藻酸纳) | |||
NGF(%) | 1 | 5 | 4 |
bFGF(%) | 5 | 4 | |
复方红芪液(%) | 7 | ||
凝固浴水溶液 | |||
氯化钙(%) | 10 | 5 | 0.7 |
*神经生长因子(%) | NGF 0.1 | 1(复合1∶3∶4) | 6(复合1∶2∶3) |
醋酸处理液(第一次) | |||
*神经生长因子(%) | NGF 0.1 | 1(复合1∶3∶4) | 6(复合1∶2∶3) |
稀醋酸(%) | 1(处理三次) | 5(处理二次) | 1(处理三次) |
甲壳胺处理液(第二次): | |||
脱乙酰度(%) | 70 | 82 | 90 |
分子量(万) | 50 | 30 | 15 |
浓度(%) | 0.5 | 1.5 | 3 |
神经生长因子(%) | NGF 0.1 | 1(复合1∶3∶4) | 6(复合1∶2∶3) |
温度(℃) | 1 | 4 | 10 |
产品 | |||
海藻酸∶甲壳胺∶海藻酸钙∶神经生长因子 | 1∶0.72∶0.62∶0.007 | 1∶0.86∶0.46∶0.07 | 1∶0.91∶0.39∶0.12 |
内径(mm) | 0.7 | 1.2 | 1.5 |
壁厚(mm) | 0.1 | 0.18 | 0.2 |
性能 | |||
强度 | 良好 | 良好 | 良好 |
抗水溶性 | 一般 | 良好 | 良好 |
生物吸收 | 5周 | 7周 | 8周 |
炎症反应 | 无 | 无 | 无 |
展趾反应 | 10周 | 10周 | 9周 |
Claims (16)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 01134542 CN1239207C (zh) | 2001-11-06 | 2001-11-06 | 一种人工生物套管及其制造方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 01134542 CN1239207C (zh) | 2001-11-06 | 2001-11-06 | 一种人工生物套管及其制造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1416914A CN1416914A (zh) | 2003-05-14 |
CN1239207C true CN1239207C (zh) | 2006-02-01 |
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Application Number | Title | Priority Date | Filing Date |
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CN 01134542 Expired - Lifetime CN1239207C (zh) | 2001-11-06 | 2001-11-06 | 一种人工生物套管及其制造方法 |
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CN (1) | CN1239207C (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101322860B (zh) * | 2007-06-12 | 2012-01-11 | 中南大学 | 可降解血管吻合套管及其制备方法 |
CN103371857A (zh) * | 2012-04-12 | 2013-10-30 | 北京汇福康医疗技术有限公司 | 复合型生物套管及其制备方法和应用 |
CN105833342A (zh) * | 2016-03-18 | 2016-08-10 | 南开大学 | 一种内径可控的海藻酸钠水凝胶空管的制备方法 |
CN105688273A (zh) * | 2016-03-18 | 2016-06-22 | 南开大学 | 一种海藻酸钠水凝胶空管的制备方法 |
CN107469144B (zh) * | 2017-07-29 | 2020-10-02 | 青岛慧生惠众生物科技有限公司 | 一种壳聚糖基复合神经导管及其制备方法和应用 |
CN110721345A (zh) * | 2018-07-17 | 2020-01-24 | 中国科学院大连化学物理研究所 | 一种包载细胞的超薄空腔复合微纤维材料的制备方法 |
CN110541209B (zh) * | 2019-09-19 | 2021-08-10 | 东华大学 | 一种基于反应性纺丝的水凝胶光导纤维的连续制备方法 |
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2001
- 2001-11-06 CN CN 01134542 patent/CN1239207C/zh not_active Expired - Lifetime
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Publication number | Publication date |
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CN1416914A (zh) | 2003-05-14 |
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Owner name: BEIJING HUIFUKANG MEDICAL TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: BEIJING YIMIN WEIKANG TECHNOLOGY CO., LTD. Effective date: 20100122 Owner name: BEIJING YIMIN WEIKANG TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: CHINESE TEXTILE ACADEMY Effective date: 20100122 |
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Effective date of registration: 20100122 Address after: Building 20, Kang Sheng Industrial Park, 11 Kangding street, Yizhuang street, Beijing economic and Technological Development Zone, Patentee after: Beijing 3H Medical Technology Co.,Ltd. Address before: Beijing City, Chaoyang District No. 39 East Third Ring Road, SOHO District North office building A block 19 layer 2203 rooms zip code: 100020 Patentee before: Beijing Yimin Wei Kang Technology Co.,Ltd. Effective date of registration: 20100122 Address after: Beijing City, Chaoyang District No. 39 East Third Ring Road, SOHO District North office building A block 19 layer 2203 rooms zip code: 100020 Patentee after: Beijing Yimin Wei Kang Technology Co.,Ltd. Address before: 3 Chaoyang Li Zhong street, Chaoyang Gate, Beijing, zip code: 100025 Co-patentee before: PEKING UNIVERSITY PEOPLE'S Hospital Patentee before: CHINA TEXTILE ACADEMY |
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Address after: In Beijing economic and Technological Development Zone, two street 100176 8 Beijing City Hospital No. 18 building 3 layer, 4 layer, 5 layer 504-520 room Patentee after: BEIJING 3H MEDICAL TECHNOLOGY CO.,LTD. Address before: 100176 Beijing economic and Technological Development Zone, Kangding street, No., Kang Sheng Industrial Park, building 20, building 11 Patentee before: Beijing 3H Medical Technology Co.,Ltd. |
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