CN1235023A - Mixed povidone iodine disinfectant and preparing method thereof - Google Patents
Mixed povidone iodine disinfectant and preparing method thereof Download PDFInfo
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- CN1235023A CN1235023A CN 99114144 CN99114144A CN1235023A CN 1235023 A CN1235023 A CN 1235023A CN 99114144 CN99114144 CN 99114144 CN 99114144 A CN99114144 A CN 99114144A CN 1235023 A CN1235023 A CN 1235023A
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- povidone iodine
- distilled water
- disinfectant
- mixed
- spice
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Abstract
A mixed povidone iodine disinfectant for preventing and auxiliarily curing veneral disease is prepared from povidone iodine (1-10%), pherylmethanol (1-2%), polyvinylpyrrolidinone (1-3%) and distilled water (85-97%) through adding povidone iodine to polyvinyl pyrrolidinone, stirring, diluting with distilled water, diluting phenylmethanol with distilled water, mixing said both kinds of solution,and diluting to defined concentration.
Description
The present invention relates to the disinfectant that a kind of skin surface is used, in particular for the disinfectant of prevention and auxiliary treatment sexually transmitted disease (STD).
The disinfectant that is used for skin surface at present has many kinds, and be used to prevent disinfectant also fewer with the auxiliary treatment sexually transmitted disease (STD), at present the widely used in the world disinfectant that is used for prevention of STD is a povidone iodine, and this kind disinfectant solution is considered at present a kind of wide spectrum, low toxicity, efficient, safe disinfectant solution.But at present the povidone iodine disinfectant solution mostly is folk prescription, directly use after promptly directly adding water with solid povidone iodine, because iodine wherein is more active, and highly volatile, so the quality instability of this kind disinfectant solution, the shelf-life is short, the curative effect reduction.
Purpose of the present invention just provides a kind of steady quality, long shelf-life, and the curative effect height, iodine is volatile mixed povidone iodine disinfectant and preparation method thereof not.
The component that mixed povidone iodine disinfectant of the present invention is counted by weight percentage is:
Povidone iodine 1.00～10.00%
Benzyl alcohol 1.00～2.00%
Polyvinylpyrrolidone 1.00～3.00%
Distilled water 97.00～85.00%
In this disinfectant, can also add glycerol, spice, the component after it adds count by weight percentage into:
Povidone iodine 1.00～10.00%
Benzyl alcohol 1.00～2.00%
Polyvinylpyrrolidone 1.00～3.00%
Glycerol 3.00～6.00%
Mentholum (spice 1) 0.01～0.02%
Osmanthus flower fragrance (spice 2) 0.1～0.2%
Distilled water 93.89～78.78%
Its preparation method is:
1. at first povidone iodine is added polyvinylpyrrolidone, adding distil water stirring gradually makes it to dissolve in distilled water fully after stirring.
2. benzyl alcohol is added distilled water diluting.
3. the benzyl alcohol after will diluting adds the povidone iodine and the polyvinylpyrrolidonesolution solution of dissolving fully in distilled water, stirs the concentration requirement that the back adding distil water is diluted to regulation.
The preparation method that adds spice and glycerol in this disinfectant is:
1. at first povidone iodine is added polyvinylpyrrolidone, add distilled water diluting after stirring gradually and stir, make it to dissolve in distilled water fully.
2. in glycerol, add the spice Mentholum earlier, heat, make it to dissolve fully, when treating that temperature is reduced to 25 ℃ of left and right sides, add the spice osmanthus flower fragrance, add benzyl alcohol afterwards again, last adding distil water dilution to 35 ℃～45 ℃.
3. the ready-formed solution of above two parts is mixed, adding distil water is diluted to the concentration requirement of regulation then.
The invention has the advantages that:
1. steady quality owing to added benzyl alcohol in this disinfectant solution, makes available iodine wherein not volatile, therefore can keep the curative effect of this disinfectant solution constant for a long time, and can long preservation.
2. curative effect height.Owing in this disinfectant solution, added polyvinylpyrrolidone, prolong the time of the sterilizing of povidone iodine, make its performance better, can play the effect that heightens the effect of a treatment.Can play the effect that prevents with the auxiliary treatment sexually transmitted disease (STD).
3. after having added essence and glycerol, except that having fragranced, when spreading upon skin surface or irrigation and disinfection position, antipruritic pain relieving, anti-allergic effects are arranged during use, the discomfort when in the past not using other disinfectant solution and can eliminate abnormal flavour.
Embodiments of the invention are as follows:
Example 1: count by weight percentage, get:
Povidone iodine 1.00% i.e. 100 grams
Benzyl alcohol 1.00% i.e. 100 grams
Polyvinylpyrrolidone 1.00% i.e. 100 grams
Distilled water 97.00% i.e. 9700 grams
The operating procedure of its preparation is: at first 100 gram povidone iodine are added and stir in the 100 gram polyvinylpyrrolidones and to add 5000 gram distilled water dilutings standby.And then get 100 the gram benzyl alcohol add therein 4700 the gram distilled water dilutings standby.At last above ready-formed two kinds of solution being mixed stirs promptly can be made into the mixed povidone iodine disinfectant that gross weight is 10000 grams.
Example 2: count by weight percentage, get:
Povidone iodine 2.50% i.e. 250 grams
Benzyl alcohol 1.50% i.e. 150 grams
Polyvinylpyrrolidone 2.00% i.e. 200 grams
Distilled water 94% i.e. 9400 grams
The operating procedure of its preparation is identical with example 1, and making gross weight at last is the mixed povidone iodine disinfectant solution of 10000 grams.
Example 3: count by weight percentage, get:
Povidone iodine 10.00% i.e. 1000 grams
Benzyl alcohol 2.00% i.e. 200 grams
Polyvinylpyrrolidone 3.00% i.e. 300 grams
Distilled water 85% i.e. 8500 grams
The operating procedure of its preparation and example, identical, making gross weight at last is the mixed povidone iodine disinfectant solution of 10000 grams.
Example 4: count by weight percentage, get:
Povidone iodine 2.50% i.e. 250 grams
Benzyl alcohol 1.50% i.e. 150 grams
Polyvinylpyrrolidone 2.00% i.e. 200 grams
Glycerol 5.00% i.e. 500 grams
Mentholum 0.015% i.e. 1.5 grams
Osmanthus flower fragrance 0.15% i.e. 15 grams
Distilled water 88.835% i.e. 8883.5 grams
Its preparation manipulation step is: at first 250 gram povidone iodine are added the polyvinylpyrrolidone of 200 grams, it is standby that the back that stirs adds 5000 gram distilled water dilutings.And then get the Mentholums that 500 gram glycerol add 1.5 grams and heat to 40 ℃, add osmanthus flower fragrance 15 grams when being cooled to 25 ℃ after treating to dissolve fully, add 150 gram benzyl alcohol afterwards again and 3883.5 gram distilled water dilutings are standby.With above two kinds of ready-formed mixed liquor mixing stirrings, promptly being prepared into gross weight is the mixed povidone iodine disinfectant of 10000 grams at last.
Claims (4)
1. a mixed povidone iodine disinfectant is made up of povidone iodine and other solvent, it is characterized in that the component that this disinfectant is counted by weight percentage is:
Povidone iodine 1.00～10.00%
Benzyl alcohol 1.00～2.00%
Polyvinylpyrrolidone 1.00～3.00%
Distilled water 97.00～85.00%
2. mixed povidone iodine disinfectant according to claim 1 is characterized in that can also adding glycerol in this disinfectant, spice, the component after it adds count by weight percentage into:
Povidone iodine 1.00～10.00%
Benzyl alcohol 1.00～2.00%
Polyvinylpyrrolidone 1.00～3.00%
Glycerol 3.00～6.00%
Mentholum (spice 1) 0.01～0.02%
Osmanthus flower fragrance (spice 2) 0.1～0.2%
Distilled water 93.89～78.78%
3. the preparation method of a mixed povidone iodine disinfectant is characterized in that its preparation method is:
1. at first povidone iodine is added polyvinylpyrrolidone, adding distil water stirring gradually makes it to dissolve in distilled water fully after stirring.
2. benzyl alcohol is added distilled water diluting.
3. the benzyl alcohol after will diluting adds the povidone iodine and the polyvinylpyrrolidonesolution solution of dissolving fully in distilled water, stirs the concentration requirement that the back adding distil water is diluted to regulation.
4. the preparation method of mixed povidone iodine disinfectant according to claim 3 is characterized in that the preparation method that adds spice and glycerol in this disinfectant is:
1. at first povidone iodine is added polyvinylpyrrolidone, add distilled water diluting after stirring gradually and stir, make it to dissolve in distilled water fully.
2. in glycerol, add the spice Mentholum earlier, heat, make it to dissolve fully, when treating that temperature is reduced to 25 ℃ of left and right sides, add the spice osmanthus flower fragrance, add benzyl alcohol afterwards again, last adding distil water dilution to 35 ℃～45 ℃.
3. the ready-formed solution of above two parts is mixed, adding distil water is diluted to the concentration requirement of regulation then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99114144A CN1092050C (en) | 1999-04-09 | 1999-04-09 | Mixed povidone iodine disinfectant and preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99114144A CN1092050C (en) | 1999-04-09 | 1999-04-09 | Mixed povidone iodine disinfectant and preparing method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1235023A true CN1235023A (en) | 1999-11-17 |
| CN1092050C CN1092050C (en) | 2002-10-09 |
Family
ID=5277259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99114144A Expired - Fee Related CN1092050C (en) | 1999-04-09 | 1999-04-09 | Mixed povidone iodine disinfectant and preparing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1092050C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102550601A (en) * | 2010-12-22 | 2012-07-11 | 昆明振华制药厂有限公司 | Iodine disinfection liquid and preparation method thereof |
| CN102698358A (en) * | 2012-06-14 | 2012-10-03 | 杭州普瑞美克生物科技有限公司 | Preparation method for disposable compound iodine medical disinfecting large cotton bar |
| CN106236772A (en) * | 2016-08-30 | 2016-12-21 | 北京安洁康生物科技有限公司 | Pasture disinfectant for nipples of dairy cows and its preparation method and application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063598A (en) * | 1991-02-01 | 1992-08-19 | 张慧贤 | The production method of quick-effective iodine disinfectant |
-
1999
- 1999-04-09 CN CN99114144A patent/CN1092050C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102550601A (en) * | 2010-12-22 | 2012-07-11 | 昆明振华制药厂有限公司 | Iodine disinfection liquid and preparation method thereof |
| CN102698358A (en) * | 2012-06-14 | 2012-10-03 | 杭州普瑞美克生物科技有限公司 | Preparation method for disposable compound iodine medical disinfecting large cotton bar |
| CN106236772A (en) * | 2016-08-30 | 2016-12-21 | 北京安洁康生物科技有限公司 | Pasture disinfectant for nipples of dairy cows and its preparation method and application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1092050C (en) | 2002-10-09 |
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