CN1092050C - Mixed povidone iodine disinfectant and preparing method thereof - Google Patents
Mixed povidone iodine disinfectant and preparing method thereof Download PDFInfo
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- CN1092050C CN1092050C CN99114144A CN99114144A CN1092050C CN 1092050 C CN1092050 C CN 1092050C CN 99114144 A CN99114144 A CN 99114144A CN 99114144 A CN99114144 A CN 99114144A CN 1092050 C CN1092050 C CN 1092050C
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- povidone iodine
- distilled water
- disinfectant
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Abstract
The present invention relates to a mixed povidone iodine disinfecting agent mainly used for preventing and treating venereal diseases in an auxiliary mode. The present invention contains the following ingredients: 1.00 to 10.00% of povidone iodine, 1.00 to 2.00% of benzyl alcohol, 1.00 to 3.00% of polyethylene pyrrolidone and 97.00 to 85.00% of distilled water. A preparation method comprises the following steps: the povidone iodine is added to the polyethylene pyrrolidone; after the povidone iodine and the polyethylene pyrrolidone are stirred, the distilled water is added for dilution and use; the distilled water is added to the benzyl alcohol to be diluted; finally, the two solutions which are prepared in advance are mixed and diluted until the specified concentration is reached, and the mixed povidone iodine disinfecting agent of the present invention is prepared.
Description
One, technical field
The present invention relates to the disinfectant that each skin surface is used, in particular for the disinfectant of prevention and auxiliary treatment sexually transmitted disease (STD).
Two, background technology
The disinfectant that is used for skin surface at present has many kinds, and be used to prevent disinfectant also fewer with the auxiliary treatment sexually transmitted disease (STD), at present the widely used in the world disinfectant that is used for prevention of STD is a povidone iodine, and this kind disinfectant solution is considered at present a kind of wide spectrum, low toxicity, efficient, safe disinfectant solution.But at present the povidone iodine disinfectant solution mostly is folk prescription, directly use after promptly directly adding water with solid povidone iodine, because iodine wherein is more active, and highly volatile, so the quality instability of this kind disinfectant solution, the shelf-life is short, the curative effect reduction.
Three, technology contents
1, goal of the invention:
Purpose of the present invention just provides a kind of steady quality, long shelf-life, the poly-dimension of the not volatile mixed type of curative effect height, iodine handle iodine disinfectant and preparation method thereof.
2, technical scheme:
Mixed povidone iodine disinfectant of the present invention is made up of povidone iodine and other solvent, and the component that this disinfectant is counted by weight percentage is: povidone iodine 1.00～10.00%, benzyl alcohol 1.00～2.00%, polyvinylpyrrolidone 1.00～3.00, distilled water 97.00～85.00%; In this disinfectant, can also add glycerol, spice, the component after it adds are counted by weight percentage and are povidone iodine 1.00～10.00%, benzyl alcohol 1.00～2.00%, polyvinylpyrrolidone 1.00～3.00%, glycerol 3.00～6.00%, Mentholum (spice 1) 0.01～0.02%, osmanthus flower fragrance (spice 2) 0.1～0.2%, distilled water 93.89～78.78%; Its preparation method is: 1. povidone iodine is added in the polyvinylpyrrolidone, after stirring, add distilled water gradually, stirring makes it to be dissolved in fully in the distilled water; 2. distilled water is added in the benzyl alcohol; 3. the benzyl alcohol adding after will diluting is dissolved in the povidone iodine and polyvinylpyrrolidonesolution solution of distilled water fully, stirs back adding distilled water alkene and releases to the concentration of regulation; Add glycerol in this disinfectant, the preparation method behind the spice is: 1. povidone iodine is added in the polyvinylpyrrolidone, after stirring, add distilled water gradually, stirring makes it to be dissolved in fully in the distilled water water; 2. in glycerol, add the spice Mentholum, be heated to 35～45 ℃, make it to dissolve fully, when treating that temperature is reduced to 25 ℃, add the spice osmanthus flower fragrance, add benzyl alcohol again, add distilled water diluting at last; 3. the ready-formed solution of above two parts is mixed, add the concentration of distilled water diluting then to regulation.。
3, technique effect:
The invention has the advantages that:
1, steady quality owing to added benzyl alcohol in this disinfectant solution, makes available iodine wherein not volatile, therefore can keep the curative effect of this disinfectant solution constant for a long time, and can long preservation.
2, curative effect height.Owing in this disinfectant solution, added polyvinylpyrrolidone, prolong the time of the sterilizing of povidone iodine, make its performance better, can play the effect that prevents with the auxiliary treatment sexually transmitted disease (STD).
3, added essence and glycerol after, except that having fragranced, when spreading upon skin surface or irrigation and disinfection position, antipruritic pain relieving is arranged during use, anti-allergic effects, discomfort and can eliminate abnormal flavour when in the past not using other disinfectant solution.
Four, the specific embodiment
Embodiments of the invention are as follows:
Example 1: count by weight percentage, get:
Povidone iodine 1.0% i.e. 100 grams
Benzyl alcohol 1.0% i.e. 100 grams
Polyvinylpyrrolidone 1.00% i.e. 100 grams
Distilled water 97.00% i.e. 9700 grams
The operating procedure of its preparation is: at first 100 gram povidone iodine are added and stir in the 100 gram polyvinylpyrrolidones and to add 5000 gram distilled water dilutings standby.And then get 100 the gram benzyl alcohol add therein 4700 the gram distilled water dilutings standby.At last above ready-formed two kinds of solution being blended in stirs promptly can be made into the mixed povidone iodine disinfectant that gross weight is 10000 grams.
Example 2: count by weight percentage, get:
Povidone iodine 2.5% i.e. 250 grams
Benzyl alcohol 1.50% i.e. 150 grams
Polyvinylpyrrolidone 2.00% i.e. 200 grams
Distilled water 94.% i.e. 9400 grams
The operating procedure of its preparation is identical with example 1, and making gross weight at last is the mixed povidone iodine disinfectant solution of 10000 grams.
Example 3: count by weight percentage, get:
Povidone iodine 10.0% i.e. 1000 grams
Benzyl alcohol 2.0% i.e. 200 grams
Polyvinylpyrrolidone 3.00% i.e. 300 grams
Distilled water 85% i.e. 8500 grams
The operating procedure of its preparation is identical with example 1, and making gross weight at last is the mixed povidone iodine disinfectant solution of 10000 grams.
Example 4: count by weight percentage, get:
Povidone iodine 2.50% i.e. 250 grams
Benzyl alcohol 1.50% i.e. 150 grams
Polyvinylpyrrolidone 2.00% i.e. 200 grams
Glycerol 5.00% i.e. 500 grams
Mentholum 0.015% i.e. 1.5 grams
Osmanthus flower fragrance 0.15% i.e. 15 grams
Distilled water 88.835% i.e. 8883.5 grams
Its preparation manipulation step is: at first 250 gram povidone iodine are added the polyvinylpyrrolidone of 200 grams, it is standby that the back that stirs adds 5000 gram distilled water dilutings.And then get the Mentholums that 500 gram glycerol add 1.5 grams and heat to 40 ℃, add osmanthus flower fragrance 15 gram benzyl alcohol when being cooled to 25 ℃ after treating to dissolve fully and 3883.5 gram distilled water dilutings are standby.With above two kinds of ready-formed mixed liquor mixing stirrings, promptly being prepared into gross weight is the mixed povidone iodine disinfectant of 10000 grams at last.
Claims (4)
1, a kind of mixed povidone iodine disinfectant is made up of povidone iodine and other solvent, it is characterized in that the component that this disinfectant is counted by weight percentage is:
Povidone iodine 1.00～10.00%
Benzyl alcohol 1.00～2.00%
Polyvinylpyrrolidone 1.00～3.00%
Distilled water 97.00～85.00%.
2, mixed povidone iodine disinfectant according to claim 1 is characterized in that can also adding glycerol in this disinfectant, spice, the component after it adds count by weight percentage into:
Povidone iodine 1.00～10.00%
Benzyl alcohol 1.00～2.00%
Polyvinylpyrrolidone 1.00～3.00%
Glycerol 3.00～6.00%
Mentholum (spice 1) 0.01～0.02%
Osmanthus flower fragrance (spice 2) 0.1～0.2%
Distilled water 93.89～78.78%.
3, a kind of preparation method of povidone iodine disinfectant as claimed in claim 1 is characterized in that its preparation method is:
1. povidone iodine is added in the polyvinylpyrrolidone, after stirring, add distilled water gradually, stirring makes it to be dissolved in fully in the distilled water;
2. distilled water is added in the benzyl alcohol;
3. the benzyl alcohol adding after will diluting is dissolved in the povidone iodine and polyvinylpyrrolidonesolution solution of distilled water fully, stirs back adding distilled water alkene and releases to the concentration of regulation.
4, a kind of preparation method of povidone iodine disinfectant as claimed in claim 2 is characterized in that its preparation method is:
1. povidone iodine is added in the polyvinylpyrrolidone, after stirring, add distilled water gradually, stirring makes it to be dissolved in fully in the distilled water water;
2. in glycerol, add the spice Mentholum, be heated to 35～45 ℃, make it to dissolve fully, when treating that temperature is reduced to 25 ℃, add the spice osmanthus flower fragrance, add benzyl alcohol again, add distilled water diluting at last;
3. the ready-formed solution of above two parts is mixed, add the concentration of distilled water diluting then to regulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99114144A CN1092050C (en) | 1999-04-09 | 1999-04-09 | Mixed povidone iodine disinfectant and preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99114144A CN1092050C (en) | 1999-04-09 | 1999-04-09 | Mixed povidone iodine disinfectant and preparing method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1235023A CN1235023A (en) | 1999-11-17 |
| CN1092050C true CN1092050C (en) | 2002-10-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99114144A Expired - Fee Related CN1092050C (en) | 1999-04-09 | 1999-04-09 | Mixed povidone iodine disinfectant and preparing method thereof |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102550601A (en) * | 2010-12-22 | 2012-07-11 | 昆明振华制药厂有限公司 | Iodine disinfection liquid and preparation method thereof |
| CN102698358A (en) * | 2012-06-14 | 2012-10-03 | 杭州普瑞美克生物科技有限公司 | Preparation method for disposable compound iodine medical disinfecting large cotton bar |
| CN106236772B (en) * | 2016-08-30 | 2018-08-17 | 北京安洁康生物科技有限公司 | Pasture disinfectant for nipples of dairy cows and its preparation method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063598A (en) * | 1991-02-01 | 1992-08-19 | 张慧贤 | The production method of quick-effective iodine disinfectant |
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1999
- 1999-04-09 CN CN99114144A patent/CN1092050C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063598A (en) * | 1991-02-01 | 1992-08-19 | 张慧贤 | The production method of quick-effective iodine disinfectant |
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| CN1235023A (en) | 1999-11-17 |
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