CN1234349C - Fragrance chewing gum for preventing from tooth-decay - Google Patents
Fragrance chewing gum for preventing from tooth-decay Download PDFInfo
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- CN1234349C CN1234349C CN 02119462 CN02119462A CN1234349C CN 1234349 C CN1234349 C CN 1234349C CN 02119462 CN02119462 CN 02119462 CN 02119462 A CN02119462 A CN 02119462A CN 1234349 C CN1234349 C CN 1234349C
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- chewing gum
- mentholum
- tooth
- flos lonicerae
- tea polyphenols
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Abstract
The present invention discloses fragrant chewing gum for preventing decayed teeth, which uses honeysuckle, tea polyphenol, menthol, amomum cardamomum, xylitol, sorbitol, aspartame, gum and a gum base as raw materials to make block agents by grinding, mixing stirring, tableting and slicing according to different characteristics of the raw materials. The present invention has the advantages of unique formulas and preparation methods, and has the obvious effects of elimination of decayed tooth causing factors, maintenance of the ecological balance of a mouth cavity and decayed tooth prevention.
Description
Technical field
The present invention relates to a kind of dental care product, relate to a kind of tooth fragrance chewing gum for preventing from tooth-decay specifically, the invention still further relates to the preparation method of this chewing gum.
Background technology
Claiming that medically " dental caries " is dental caries, is human commonly encountered diseases, frequently-occurring disease.Dental caries not only destroys tooth, influences masticatory function, overslaugh digestion, and the whole body that more influences the child is grown, and particularly jaw is facial grows.Because potential hazard is serious, World Health Organization (WHO) has been listed as dental caries, tumor and cardiovascular diseases three big keypoint control diseases.
At present, sell chewing gum on the market with preventing decayed tooth, as " the daring and resolution sugar-free chewing gum " of Guangzhou " benefit reaches sugar-free chewing gum ", Beijing Hua Aikang company " fragrant mouthful of sugar of Hua Aikang sugar-free ", jiangsu wuxi Ji Bao company, Fujian for a long time princes and dukes department " arrow king chewing gum " its mainly prepare burden and be Pyrusussuriensis ferment, gum base, xylitol, lecithin, aspartame, acesulfame potassium, antioxidant (BHT).This chewing gum mainly uses does not have the sugar substitute of fermentation to reach anticaries action by the absorption of restricted fermentation carbohydrate and by chewing of tooth.From the stomatology angle analysis, prescription has all been paid attention to sugar-free, has been adopted nothing to cause the sugar alcohols sweeting agent of dental caries effect, replaces being utilized the sucrose that causes dental caries by antibacterial easily, and this can only illustrate this little factor of sucrose of having eliminated soluble nutrient in the dental caries food factor.And utilize sugar alcohols sweeting agent and the secretion of Chewing gum nurse saliva stimulating to increase the saliva of buccal cavity amount, by the friction effect that the mechanical flushing action and the chewing gum of saliva are chewed, remove the food detritus that stores in dental surface.But really can not kill or suppress the initiation factor-antibacterial of dental caries.Thus, the origin cause of formation of dental caries is relevant with time tetrad factor with microorganism, food, host, the Anticarious tooth chewing gum that non-above-mentioned raw materials makes can be intervened control from basic each stage that dental caries is taken place, and therefore, needs Anticarious tooth chewing gum is done further improvement and perfect.
Summary of the invention
The object of the present invention is to provide a kind of chewing gum with antiseptic caries-preventing effect.
Another object of the present invention also provides the preparation method of this chewing gum.
Solution of the present invention is to be guiding theory with the oral cavity ecological theory, understanding for modern cariology tetrad factor etiology, with reference to the principle of modern pharmacological research, from the Chinese medicine and pharmacy treasure-house, choose pure natural plant medical herbs, extract its elite with anti-dental caries, periodontal disease unique effects.Adopting glue nurse base is carrier, makes the effective efficiency composition slowly discharge, bring into play lastingly effect in the process of chewing, and realizes intervening the occurrence condition of control dental caries, periodontal disease, causes the dental caries factor and safeguards the oral cavity ecological balance and play to eliminate.The generation of caries prevention, periodontal disease.
Chewing gum of the present invention is made (consumption is a weight portion) by following component:
Flos Lonicerae 12.5-25 part tea polyphenols 0.4-0.5 part Mentholum 0.15-0.2 part
Fructus Amomi Rotundus 1.5-2 part xylitol 30-40 part sorbitol 65-75 part
Glue nurse 10-12 part gum base 8-10 part aspartame 2-3 part
Preferred weight part of chewing gum of the present invention is:
Flos Lonicerae 8-12.5 part tea polyphenols 0.3-0.4 part Mentholum 0.1-0.15 part
Fructus Amomi Rotundus 1-1.5 part xylitol 25-30 part sorbitol 55-65 part
Glue nurse 8-10 part gum base 7-9 part aspartame 1-2 part
Optimum weight part of chewing gum of the present invention is:
2 parts of 0.2 portion of Fructus Amomi Rotunduss of 0.3 part of Mentholum of 8 parts of tea polyphenols of Flos Lonicerae
1 part of 8 parts of aspartame of 10 parts of gum base of 55 parts of glue nurses of 25 parts of sorbitol of xylitol
The preparation method of above-mentioned each component being made chewing gum is:
1, choosing Flos Lonicerae, tea polyphenols, Mentholum quenches and gets thing;
2, get the Fructus Amomi Rotundus peeling, the Semen Vignae Cylindricae KOUREN is crushed to 120 order fine powders;
3, it is standby to get the Mentholum heat fused;
4, Flos Lonicerae, tea polyphenols are quenched got thing and stir into solution for standby with an amount of 70 ℃ of warm distilled water;
5, xylitol, sorbitol, aspartame being added an amount of 80 ℃ of left and right sides dissolved in distilled water, to stir into syrup standby;
6, glue nurse, gum base being made glue nurse base and syrup is heated to and carries out stirring and evenly mixing under 85-100 ℃, transfer to pH value 6.5-7, be cooled to and slowly add Flos Lonicerae, tea polyphenols under 70-85 ℃ while stirring and quench and get thing solution, add Fructus Amomi Rotundus fine powder, Mentholum respectively again, be cooled to solid, promptly obtain the piece goods through tabletting, section.
For showing that fragrance chewing gum for preventing from tooth-decay of the present invention is to intervening and preventing preventive effect, characteristics and the mechanism of dental caries, periodontal disease to be expressed as follows:
Flos Lonicerae: be the caprifoliaceae plant alabastrum.Cold in nature, sweet in the mouth is traditional Chinese medical science heat and toxic materials clearing away medicine, is one of main medicine of treatment oral cavity and throat diseases.It is the medicine-food two-purpose natural Chinese medicine treasure of health authorization.Modern study proves, mainly contains luteolin, inositol Saponin, and compositions such as chlorogenic acid, isochlorogenic acid have antibiotic, the antivirus action of broad-spectrum, effects such as enhancing body defensive enginery.Wherein chlorogenic acid and isochlorogenic acid are main antibiotic compositions.And dental caries and periodontal disease pathogenic bacterium there is very strong bacteriostasis.
Tea polyphenols: be effective bioactive ingredients of from Folium Camelliae sinensis, quenching and getting.Folium Camelliae sinensis, cool in nature, sweet in the mouth, hardship, main purine-containing Alkaloid, tea polyphenols, vitamin and trace element.Confirm that after deliberation tea polyphenols has resisting fatigue, defying age, antitumor, broad-spectrum antibacterial action.Cariogenic bacteria (Streptococcus mutans) growth, product acid, adhesion had specific inhibitory effect.
Mentholum: be the thing of from the natural plant Herba Menthae, purifying.Herba Menthae, cool in nature, acrid in the mouth.It is one of Chinese traditional treatment oral cavity and throat diseases principal agent.Modern study, volatile oil such as menthol, menthone are Main Ingredients and Appearances.Mentholum has very strong bactericidal action.The essential oil of this plant extract can reduce dental plaque and form, and stops bacterial plaque growth effect.
Herba Menthae, Fructus Amomi Rotundus, fragrant odour, Xin Liang integrate antibiotic, are good for the stomach, help digestion, the effect in flavoring, pure and fresh oral cavity.
Xylitol, sorbitol are good to microbial stability, and main cariogenic bacteria Streptococcus mutans is had certain inhibitory action.And can be utilized by the minority antibacterial, play the inhibition cariogenic bacteria, help probiotics, safeguard oral cavity micropopulation balanced action.
Xylitol, sorbitol, aspartame are as sugar substitute, and restriction sugar is taken in, and eliminate glycolysis and produce acid, safeguard that ph value of oral cavity is relatively stable, eliminate nutrition and the energy source of antibacterial, and needed sour environment.
Glue nurse base: be the base starting material of making chewing gum, bubble gum, have very strong elasticity and adhesive capacity.The function of its carrier is to be a kind of medicament slow release technology and method of uniqueness in the chewing gum network structure with the filling of antiseptic caries-preventing composition, can slowly discharge at the process Chinese medicine of chewing, be distributed in corona interlock cake crack ditch split with outmoded cavity in, and mechanical friction in the masticatory movement, adhesion, bring into play effect lastingly.
The characteristics of this fragrance chewing gum for preventing from tooth-decay are: by chewing fragrance chewing gum for preventing from tooth-decay after meal, can in time remove the food detritus that stores at the non-self-cleaning area in oral cavity, make it lose zymolysis and produce sour chance, prevent from that hyper acid to make ph value of oral cavity low excessively, safeguard the balance of little ecology.Also eliminated simultaneously nutrition and the energy source of antibacterial, the non-self-cleaning area of antiseptic caries-preventing medicine belt entrance cavity is killed or suppressed antibacterial by chewing biting pressure from root; Mechanical friction by chewing gum, sticking removing and the flushing of saliva, buffering, a series of effect such as antibiotic, make bacterial growth, produce acid, adhesion, dental plaque cause the tooth dental caries to decrease each stage destructions that is interfered, and the condition of elimination dental caries generation, safeguards the oral cavity ecological balance.
The selected Chinese medicine of chewing gum prescription is the traditional medicine-food two-purpose natural Chinese medicine treasure of the traditional Chinese medical science of Ministry of Public Health authorization, its food additive is that the nutritional food additive with anticaries action, full side's raw material not only have unique antiseptic caries-preventing effect, and have protect the liver, blood fat reducing, be good for the stomach, pharmacological action such as resisting fatigue, mutation, slow down aging, without any side effects, suitable prevention and health care is edible for a long time.
This fragrance chewing gum for preventing from tooth-decay is through having carried out the test of fragrance chewing gum for preventing from tooth-decay prevention dental caries, method: 120 people are divided into experimental group and matched group, every group 60 people to 120 8-16 year students in middle and primary schools.Carry out the Buccodental inspection record before the experiment, experimental group every day, everyone early after meal, p.prand respectively gave the 1 anti-caries chewing gum of determining, and chewed more than 30 minutes; Commercially available sugar-free chewing gum is carefully selected in contrast for use.6 days weekly, 6 months by a definite date.
Test preceding oral cavity tooth detection
Oral cavity, experiment back tooth detection
Experimental result shows:
1, experimental group dental caries trouble number and sickness rate are starkly lower than matched group.
2, the experimental group sickness rate reduces by 47.59% before the experiment, checks before the experiment that 60 philtrums, 33 people suffer from dental caries, and sickness rate is 55%, and only 2 people morbidity of dental health 27 people is checked in the experiment back, and sickness rate is 7.41%.
3, two groups of sickness rate experiment back rising indexes: experimental group rising (58.33-55) is 3.33%, and matched group rising (65-53.33) is 11.67%, and experimental group is than matched group low 8.34%.
4, test front and back number of patients and sickness rate contrast for two groups: experimental group is than few 6 people of matched group number of the infected, and sickness rate hangs down 6.67%.
5, dental caries damage degree contrast: in the matched group, dark dental caries all increase than experimental group.
6, dental caries trouble crowd's sickness rate and dental caries decrease degree all than healthy population height, illustrate in healthy population and the dental caries trouble crowd oral cavity there be than big-difference ecological factors such as cariogenic bacteria group, caries susceptiblit, defense function and external environment, and dental caries patient susceptibility is strong.
7, this experiment is 6 months by a definite date, and anti-caries effect is more obvious.Under the not enough situation of present China dental prevention man power and material, and prevention of caries do not had any special measures, do not have under the method and measure situation simple, reliable for effect, utilize that to have the medicine food dual purpose plant medicine that unique antiseptic caries-preventing has no side effect be the effective means of prevention dental caries.Motherland's medicine disease preventing and treating precious resources that is richly stored with also is described, remains that we excavate exploitation, bring benefit to the mankind.
The specific embodiment
Take by weighing raw material by following proportioning:
Flos Lonicerae 6g tea polyphenols 0.25g Mentholum 0.05g Fructus Amomi Rotundus 1g xylitol 20g
Sorbitol 45g glue nurse 70g gum base 6g aspartame 0.5g
Preparation method is as follows:
Choose earlier the Flos Lonicerae crude drug in proportion, put and decoct in the device, add water and surpass powder 5-10cm, decoct 2 times, it is 1 hour for the first time, for the second time be twice medicinal liquid of merging in 45 minutes, be evaporated to 1: 2.5 (being that the 1kg crude drug makes the 2.5kg concentrated solution), be cooled to 45-60 ℃, add 20% lime cream suspension and transfer to about PH10, filter or centrifugal minute taking precipitate, precipitate is added 2 times of 95% ethanol grind pulping, under agitation slow Dropwise 5 0% sulphuric acid transfers to solution about PH3, fully stirring, centrifugal removal solids.Filtrate transfers to PH6.5-7.0 with alkali, reclaims ethanol, and concentrating under reduced pressure is drying to obtain the effective biotic component chlorogenic acid of Flos Lonicerae powder and quenches and get thing, chooses tea polyphenols again, Mentholum is quenched and got thing; Get the Fructus Amomi Rotundus peeling, the Semen Vignae Cylindricae KOUREN is crushed to 120 order fine powders; Getting the Mentholum heating again dissolves; Flos Lonicerae, tea polyphenols quenched get thing and stir into solution with an amount of 70 ℃ of warm distilled water; Getting xylitol, sorbitol, aspartame adds an amount of 80 ℃ of left and right sides dissolved in distilled water and stirs into syrup; Glue nurse, gum base are made glue nurse base and syrup to be heated to and to carry out stirring and evenly mixing under 85-100 ℃, transferring to pH value is 6.5-7, be cooled to slowly add Flos Lonicerae under 70-85 ℃ while stirring, tea polyphenols is quenched and is got thing solution, add Fructus Amomi Rotundus fine powder, Mentholum more respectively, be cooled to solid, through tabletting, section, promptly obtain piece agent goods, pack.
Above-mentioned Flos Lonicerae is quenched and gets thing chlorogenic acid powder.In the time of also can being repeated to the concentrating under reduced pressure step, needn't carry out dry run, gold silver medicine extract is evaporated to contains Flos Lonicerae crude drug 100% concentration and can direct matching come into operation by its above-mentioned steps.
Flos Lonicerae in above-mentioned produces to well with Linyi, Shandong.Tea polyphenols, Mentholum are that quenching of selling on the market got the thing finished product.
The source of tea polyphenols can be institute of Chinese section Folium Camelliae sinensis institute, and Shanghai intelligence reaches scientific and technological industrial corporation, Tianjin, Tianjin dragon health-care products company limited, east, Zhejiang Tea Industry Science and Technology Co., Ltd..
Mentholum is sold by food additive operating unit.Must select natural Herba Menthae purification product for use.
Above-mentioned Flos Lonicerae, tea polyphenols relate to the utensil of splendid attire, comprise that stirring rod all must not use ironwork.
Claims (3)
1, a kind of fragrance chewing gum for preventing from tooth-decay is characterized in that it is to be made by the following weight proportion raw material:
Flos Lonicerae 12.5-25 part tea polyphenols 0.4-0.5 part Mentholum 0.15-0.2 part
Fructus Amomi Rotundus 1.5-2 part xylitol 30-40 part sorbitol 65-75 part
Glue nurse 10-12 part gum base 8-10 part aspartame 2-3 part
2, by the described fragrance chewing gum for preventing from tooth-decay of claim 1, it is characterized in that described chewing gum is the piece agent.
3, a kind of method that is used to prepare claim 1 chewing gum is: choose Flos Lonicerae, tea polyphenols, Mentholum and quench and get thing; Get the Fructus Amomi Rotundus peeling, the Semen Vignae Cylindricae KOUREN is crushed to 120 order fine powders; It is standby to get the Mentholum heat fused; Flos Lonicerae, tea polyphenols quenched get thing and stir into solution for standby with an amount of 70 ℃ of warm distilled water; Xylitol, sorbitol, aspartame are added an amount of 80 ℃ of left and right sides dissolved in distilled water, and to stir into syrup standby; Glue nurse, gum base are made glue nurse base and syrup to be heated to and to carry out stirring and evenly mixing under 85-100 ℃, transfer to pH value 6.5-7, be cooled to and slowly add Flos Lonicerae, tea polyphenols under 70-85 ℃ while stirring and quench and get thing solution, add Fructus Amomi Rotundus fine powder, Mentholum respectively again, be cooled to solid, promptly obtain piece agent goods through tabletting, section.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02119462 CN1234349C (en) | 2002-05-24 | 2002-05-24 | Fragrance chewing gum for preventing from tooth-decay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02119462 CN1234349C (en) | 2002-05-24 | 2002-05-24 | Fragrance chewing gum for preventing from tooth-decay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1459307A CN1459307A (en) | 2003-12-03 |
| CN1234349C true CN1234349C (en) | 2006-01-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02119462 Expired - Fee Related CN1234349C (en) | 2002-05-24 | 2002-05-24 | Fragrance chewing gum for preventing from tooth-decay |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008045579A1 (en) * | 2006-10-11 | 2008-04-17 | Wm. Wrigley Jr. Company | Oral delivery vehicles containing a traditional chinese medicine of extract thereof |
| CN102356804A (en) * | 2011-05-10 | 2012-02-22 | 游润江 | Sugar-free chewing gum |
| CN110279025A (en) * | 2019-07-15 | 2019-09-27 | 天水师范学院 | A kind of apple polyphenol health chewing gum and preparation method thereof |
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2002
- 2002-05-24 CN CN 02119462 patent/CN1234349C/en not_active Expired - Fee Related
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| CN1459307A (en) | 2003-12-03 |
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