CN1228992A - Antipyretic granular formulation containing ramulus cinnamomi, ephedra and bupleurum root - Google Patents

Abstract

An antipyretic in the form of particles for treating fever caused by cold or unknown reasons is prepared from 12 Chinese-medicinal materials such as cinammont wigs, ephedra, bupleurum root, white peony root, scutellaria root, etc as main medicinal material, anemarrhena root, radix acoxiti praeparatea, angelica root, licorlce, ginger, jujube as auxiliary medicinal material through decocting in water three times, filter, heating to evaporate out water, preparing extract, addition of sugar and corn starch or amylin, mechanical granulating, drying and loading in bags. Its advantages include quickly taking its effect and no recurrence.

Description

Osmanthus fiber crops bavin antipyretic granule agent and production technology

The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine of the usefulness of bringing down a fever.

At present treatment cold, fever and unknown cause hyperpyrexia patient mainly contain two kinds of methods: 1, western medicine: the various antibiotic of clinical practice, antiviral agents but DeGrain or invalid.2, treatment by Chinese herbs: the Chinese traditional treatment fever caused by exogenous pathogens needs dialectical opinion to control, the suitable relieving the exterior syndrome with drugs of pungent in flavor and warm in nature of affection of exogenous wind-cold, affection due to external wind and heat should relieving the exterior syndrome with drugs of pungent in flavor and cool in nature still need in addition the differential diagnosis of diseases heresy the depth and respectively by defend, gas, battalion, blood are lived three sun, three cloudy the six channels opinions are controlled, therefore treatment is comparatively complicated.But cure mainly from the Chinese medicine preparation function of current treatment fever caused by exogenous pathogens, mostly be relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, heat-clearing and toxic substances removing, therefore substantially all be to establish for wind heat disease, be not suitable for affection of exogenous wind-cold disease, therefore indication is very simple, and it is long-term uncured to be not suitable for fever caused by exogenous pathogens, the complicated symptom of heat-transformation in pathogenic factor in the exterior is not separated and is fade-in.

Flu is the common clinical by viral infection (part patient has due to the bacterial infection), frequently-occurring disease, and the general course of disease is shorter, the prognosis bona.But the cureless patient of cold, fever is also arranged, though use various antibiotics, disease-resistant bacterium medicine and symptomatic drugs treatment still continue hyperpyrexia and make the patient feel more painful.Hyperpyrexia is very big to body consumption, and is easy to concurrent other disease and after influencing more.

The present invention seeks to disclose fiber crops bavin antipyretic granule agent of a kind of osmanthus and production technology.The present invention is effective especially to the cureless patient of cold, fever.Solve the cold, fever obstinate, or the persistent difficult problem of unknown cause hyperpyrexia, patient's misery alleviated.It is extensive that this product has indication, and the function of bringing down a fever is rapid, characteristics such as do not recur after more.

Its prescription of the present invention is (by weight):

Ramulus Cinnamomi: 2%-30%, Herba Ephedrae: 2%-30%, Radix Bupleuri: 2%-30%, the Radix Paeoniae Alba: 2%-30%, Radix Scutellariae: 2%-30%, Gypsum Fibrosum: 5%-50%, above be principal agent, and be furnished with the Rhizoma Anemarrhenae: 2%-18%, Radix Aconiti Lateralis Preparata: 2-10%, Radix Codonopsis: 2-18%, Radix Glycyrrhizae: 2-10% Rhizoma Zingiberis Recens: 2-10%, Fructus Jujubae: 2-10%.

Wherein Ramulus Cinnamomi, Herba Ephedrae, Radix Bupleuri, the Radix Paeoniae Alba, Radix Scutellariae, Gypsum Fibrosum play a major role in this side, and the Rhizoma Anemarrhenae, Radix Aconiti Lateralis Preparata, Radix Codonopsis, Radix Glycyrrhizae, Rhizoma Zingiberis Recens, Fructus Jujubae help out.

Process of the present invention is:

A. earlier with Gypsum Fibrosum, Radix Aconiti Lateralis Preparata, Radix Codonopsis, put in the extraction pot, added water boil 25-35 minute that 8-10 doubly measures;

B. adding Herba Ephedrae continued to boil 10-20 minute;

C. remove and go up foam, and then drop into all medicines, boiled 45-50 minute;

D. extract medicinal liquid after filtration;

E. with medicinal liquid heating, transpiring moisture is made the extractum of water content about 30%;

F. above-mentioned extractum is added each equivalent of Icing Sugar corn starch (or dextrin), mix, granule mechanism granule;

G. put 50-65 hothouse drying, granulate, plastic bag packing, every pouch 10 grams contain and are equivalent to crude drug 12 gram extractum.

Embodiment one:

Ramulus Cinnamomi: 20g, Herba Ephedrae: 20g, Radix Bupleuri: 20g, the Radix Paeoniae Alba: 20g,

Radix Scutellariae: 10g, Gypsum Fibrosum: 50g, the Rhizoma Anemarrhenae: 20g, Radix Aconiti Lateralis Preparata: 7.5g,

Radix Codonopsis: 20g, Radix Glycyrrhizae: 15g, Rhizoma Zingiberis Recens: 7.5g, Fructus Jujubae: 7.5g.

Embodiment two:

Ramulus Cinnamomi: 20g, Herba Ephedrae: 20g, the Radix Paeoniae Alba: 20g, Radix Scutellariae: 10g,

Gypsum Fibrosum: 50g, Radix Codonopsis: 20g, Radix Glycyrrhizae: 15g, Rhizoma Zingiberis Recens: 7.5g,

Radix Bupleuri: 20g, Fructus Jujubae: 7.5g.

The invention effect:

It is extensive that this product has indication, and the function of bringing down a fever is rapid, the characteristics such as do not recur after more. Through black dragon The river provincial institute for drug control carries out Viral experiment, and is all effective in cure to all common cold virus, especially to this year No. 7 popular viral curative effect the bests. Cold, fever is that the high heat of common disease frequently-occurring disease is controlled for a long time not move back and faced Very see that present Western medicine Chinese medicine is not good to the result for the treatment of of this disease in the bed, the high heat of unknown cause more Also be common disease, but heating cause can't determine to make especially traditional Chinese medical science doctor trained in Western medicine to feel simply helpless. Inventor's root Set forth the special book that the dialectical opinion of multiple exogenous diseases is controlled---the theory of treatise on Febrile Diseases according to Ancient Times in China, Use for reference the contained how first classical prescription of treatise on Febrile Diseases, through clinical practice for many years, develop this medicine, its The effect of bringing down a fever is fairly obvious, whole therapeutic process order 1-48 hour, and the patient takes this product 1 Body temperature namely begins to descend in hour, and the patient that the state of an illness is lighter can fully recover. The state of an illness heavier patient exist Also can bring down a fever fully in 48 hours. And its dosage form design is graininess, divides little generation by each amount Packing is taken, and carries all very convenient.

This product is carried out acute toxicity test through the institute for drug control, Heilongjiang Province, proves that this medicine is nontoxic The property. Through Heilongjiang Province Academy of Traditional Chinese Medicine Pharmaceutical Manufacturing Plant's 100 routine clinical testings, efficient 98%, cure rate 85%, no case was recurrence after more no any toxicity. The present invention solves cold, fever and controls not for a long time More, or the persistent difficult problem of the high heat of unknown cause this to alleviating patient's misery, to protect mankind Health has great importance.

Claims (2)

1. osmanthus fiber crops bavin antipyretic granule agent, its prescription is (by weight):

Ramulus Cinnamomi: 2%-30%, Herba Ephedrae: 2%-30%, Radix Bupleuri: 2%-30%, the Radix Paeoniae Alba: 2%-30%, Radix Scutellariae: 2%-30%, Gypsum Fibrosum: 5%-50%, above be principal agent, and be furnished with the Rhizoma Anemarrhenae: 2%-18%, Radix Aconiti Lateralis Preparata: 2-10%, Radix Codonopsis: 2-18%, Radix Glycyrrhizae: 2-10% Rhizoma Zingiberis Recens: 2-10%, Fructus Jujubae: 2-10%.

2. the production technology of the described osmanthus of claim 1 fiber crops bavin antipyretic granule agent, its process is:

A. earlier with Gypsum Fibrosum, Radix Aconiti Lateralis Preparata, Radix Codonopsis, put in the extraction pot, added water boil 25-35 minute that 8-10 doubly measures;

B. adding Herba Ephedrae continued to boil 10-20 minute;

C. remove and go up foam, and then drop into all medicines, boiled 45-50 minute;

D. extract medicinal liquid after filtration;

E. with medicinal liquid heating, transpiring moisture is made the extractum of water content about 30%;

F. above-mentioned extractum is added each equivalent of Icing Sugar corn starch (or dextrin), mix, granule mechanism granule;

G. put 50-65 ℃ of hothouse drying, granulate, plastic bag packing, every pouch 10 grams contain and are equivalent to crude drug 12 gram extractum.