CN1221542C - 从含有母育酚的混合物中分离母育酚的方法 - Google Patents

从含有母育酚的混合物中分离母育酚的方法 Download PDF

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Publication number
CN1221542C
CN1221542C CNB998024449A CN99802444A CN1221542C CN 1221542 C CN1221542 C CN 1221542C CN B998024449 A CNB998024449 A CN B998024449A CN 99802444 A CN99802444 A CN 99802444A CN 1221542 C CN1221542 C CN 1221542C
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China
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aqueous
tocol
extraction solvent
phase
pure
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Expired - Fee Related
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CNB998024449A
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English (en)
Chinese (zh)
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CN1314901A (zh
Inventor
小C·E·苏姆纳
J·D·蒙西尔
J·S·卡尼尔
M·K·福斯特
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Eastman Chemical Co
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Eastman Chemical Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
CNB998024449A 1998-01-29 1999-01-26 从含有母育酚的混合物中分离母育酚的方法 Expired - Fee Related CN1221542C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7296298P 1998-01-29 1998-01-29
US7296398P 1998-01-29 1998-01-29
US60/072,962 1998-01-29
US60/072,963 1998-01-29

Publications (2)

Publication Number Publication Date
CN1314901A CN1314901A (zh) 2001-09-26
CN1221542C true CN1221542C (zh) 2005-10-05

Family

ID=26753962

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB998024449A Expired - Fee Related CN1221542C (zh) 1998-01-29 1999-01-26 从含有母育酚的混合物中分离母育酚的方法
CN99802443A Pending CN1295568A (zh) 1998-01-29 1999-01-26 从含有母育酚的混合物中分离生育三烯酚的方法及其组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN99802443A Pending CN1295568A (zh) 1998-01-29 1999-01-26 从含有母育酚的混合物中分离生育三烯酚的方法及其组合物

Country Status (8)

Country Link
US (2) US6224717B1 (https=)
EP (2) EP1051411B1 (https=)
JP (2) JP2002501915A (https=)
CN (2) CN1221542C (https=)
BR (2) BR9907278A (https=)
ES (2) ES2207931T3 (https=)
MY (1) MY124273A (https=)
WO (2) WO1999038859A1 (https=)

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US6350453B1 (en) 1999-05-24 2002-02-26 American River Nutrition, Inc. Tocotrienols and geranylgeraniol from Bixa orellana byproducts
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US6706474B1 (en) * 2000-06-27 2004-03-16 Board Of Trustees Of The University Of Illinois Nucleic acid enzyme biosensors for ions
US6838104B2 (en) * 2000-12-20 2005-01-04 Archer Daniels Midland Company Process for the production of tocotrienols
US6867308B2 (en) 2001-09-19 2005-03-15 Archer-Daniels-Midland Company Process for separation of tocopherols
US6890719B2 (en) * 2002-05-10 2005-05-10 The Board Of Trustess Of The University Of Illinois Fluorescence based biosensor
US7461048B2 (en) * 2003-07-21 2008-12-02 Aureon Laboratories, Inc. Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US7416756B2 (en) * 2003-09-10 2008-08-26 Eastman Chemical Company Process for the recovery of a phytolipid composition
CA2534961C (en) * 2003-09-10 2009-06-16 Eastman Chemical Company Process for the recovery of a phytolipid composition
WO2005035490A2 (en) * 2003-10-10 2005-04-21 Yasoo Health, Inc. PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS
MY173044A (en) 2003-11-19 2019-12-20 Carotech Bhd Recovery of phytonutriens from oils
EP2471530B1 (en) 2005-06-01 2017-01-11 Edison Pharmaceuticals, Inc. Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US7892734B2 (en) * 2005-08-11 2011-02-22 The Board Of Trustees Of The University Of Illinois Aptamer based colorimetric sensor systems
US9278085B2 (en) 2006-02-22 2016-03-08 Edison Pharmaceuticals, Inc. Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US7799554B2 (en) * 2006-03-16 2010-09-21 The Board Of Trustees Of The University Of Illinois Lateral flow devices
US8415461B2 (en) * 2007-01-19 2013-04-09 The Board Of Trustees Of The University Of Illinois Amphiphilic substances and functionalized lipid vesicles including the same
US8058415B2 (en) * 2007-04-24 2011-11-15 The Board Of Trustees Of The University Of Illinois Aptamer- and nucleic acid enzyme-based systems for simultaneous detection of multiple analytes
WO2008142433A1 (en) * 2007-05-24 2008-11-27 Loders Croklaan B.V. Process for producing compositions comprising tocoherols and tocotrienols
US8409800B2 (en) * 2007-07-16 2013-04-02 The Board Of Trustees Of The University Of Illinois Nucleic acid based fluorescent sensor for copper detection
US8568690B2 (en) * 2007-07-31 2013-10-29 The Board Of Trustees Of The University Of Illinois MRI contrast agents and high-throughput screening by MRI
US8367416B2 (en) 2007-08-10 2013-02-05 The Board Of Trustees Of The University Of Illinois Nucleic acid based fluorescent sensor for mercury detection
US20090090894A1 (en) * 2007-10-05 2009-04-09 Bin Wang Separation and extraction system
US20100105039A1 (en) * 2008-06-03 2010-04-29 Yi Lu Label-free colorimetric detection
EP2344142B1 (en) 2008-09-10 2024-06-26 PTC Therapeutics, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
US8062893B2 (en) 2008-10-10 2011-11-22 The Board Of Trustees Of The University Of Illinois Fluorescent sensor for mercury
CA2741767C (en) 2008-10-28 2017-09-12 Ptc Therapeutics, Inc. Process for the production of alpha-tocotrienol and derivatives
PL2424495T3 (pl) 2009-04-28 2018-06-29 Bioelectron Technology Corporation Leczenie dziedzicznej neuropatii nerwów wzrokowych lebera i dominującego zaniku nerwu wzrokowego chinonami tokotrienolu
EP2609921A1 (en) 2009-06-25 2013-07-03 Ampere Life Sciences, Inc. Treatment of pervasive developmental disorders with tocotrienols or tocotrienol enriched extracts
US8815156B2 (en) 2010-07-19 2014-08-26 Andalyze, Inc. Sensor housing and reagent chemistry
JP2014520894A (ja) 2011-07-19 2014-08-25 エジソン ファーマシューティカルズ， インコーポレイテッド 非アルファトコトリエノールの存在下でのアルファトコトリエノールの選択的酸化のための方法
SG2013017017A (en) 2012-01-25 2014-09-26 Asahi Kasei Chemicals Corp A method of separation
EP2810940A1 (en) * 2013-06-06 2014-12-10 Sulzer Chemtech AG A Process to Prepare A Tocopherol Concentrate
US9512098B1 (en) 2014-02-03 2016-12-06 Board Of Trustees Of The University Of Arkansas Process of producing purified gamma- and delta-tocotrienols from tocol-rich oils or distillates
MY171445A (en) 2014-02-11 2019-10-15 Evonik Degussa Gmbh Method for producing vitamine e-enriched, especially tocotrienol-enriched, compositions from natural oils
EP3390377B1 (en) 2015-12-16 2026-03-25 PTC Therapeutics, Inc. Improved methods for enriching alpha-tocotrienol from mixed tocol compositions
WO2017106803A1 (en) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
MY184673A (en) * 2018-03-16 2021-04-15 Palm Nutraceuticals Sdn Bhd A process of preparing vitamin e concentrate
CN110251980B (zh) * 2019-04-22 2021-03-23 中建安装集团有限公司 一种二恶烷水溶液中提纯优品级二恶烷的装置及方法

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US2866797A (en) 1954-11-01 1958-12-30 Gen Mills Inc Improved process of isolating sterols
US3153055A (en) * 1962-03-20 1964-10-13 Eastman Kodak Co Process for separating tocopherols and sterols from deodorizer sludge and the like
US3335154A (en) 1963-06-04 1967-08-08 Eastman Kodak Co Separation of tocopherols and sterols from deodorizer sludge and the like
US4454329A (en) * 1980-07-04 1984-06-12 The Nisshin Oil Mills, Ltd. Process for preparation of tocopherol concentrates
US4480108A (en) * 1983-08-01 1984-10-30 Eastman Kodak Company Process for separation of tocopherol homologues
JPS6048981A (ja) * 1983-08-29 1985-03-16 Showa Denko Kk 高純度トコフェロ−ルの製造方法
JPS60149582A (ja) * 1984-01-14 1985-08-07 Mitsui Petrochem Ind Ltd トコフエロ−ルの精製方法
JPS60185776A (ja) * 1984-03-05 1985-09-21 Riken Vitamin Co Ltd トコフエロ−ルの精製濃縮法
US4550183A (en) 1984-08-02 1985-10-29 Henkel Corporation Purification of tocopherols
EP0171009B1 (en) * 1984-08-02 1991-05-22 HENKEL CORPORATION (a Delaware corp.) Purification of tocopherols by extraction
JPS6160619A (ja) * 1984-08-31 1986-03-28 Eisai Co Ltd 分散性粉末
JPS6193178A (ja) * 1984-10-12 1986-05-12 Agency Of Ind Science & Technol トコトリエノ−ル類の分離方法
JPS61151186A (ja) * 1984-12-24 1986-07-09 Nisshin Oil Mills Ltd:The トコトリエノ−ル類およびトコフエロ−ル類の濃縮法
DE3615029A1 (de) * 1985-05-06 1986-11-06 Henkel Corp., Minneapolis, Minn. Methanol-extraktion von tocopherol
EP0333472B1 (en) * 1988-03-16 1997-10-08 PALM OIL RESEARCH & DEVELOPMENT BOARD Production of high concentration tocopherols and tocotrienols from palm oil by-products
JPH03127730A (ja) * 1989-10-11 1991-05-30 Kikaku Nijiyuuichi:Kk ビタミンｅの製造方法
MY108071A (en) * 1990-05-23 1996-08-15 Pentad Foods Int Stabilization and recovery method for tocotrienol and tocopherol products.
US5487817A (en) * 1993-02-11 1996-01-30 Hoffmann-La Roche Inc. Process for tocopherols and sterols from natural sources
ATE289301T1 (de) * 1993-08-06 2005-03-15 Cognis Corp Wiedergewinnung von tocopherolen
US5512691A (en) * 1994-11-07 1996-04-30 Eastman Chemical Company Process for the production of tocopherol concentrates
US5660691A (en) * 1995-11-13 1997-08-26 Eastman Chemical Company Process for the production of tocotrienol/tocopherol blend concentrates
US5703252A (en) * 1995-12-13 1997-12-30 Henkel Corporation Recovery of Tocopherols

Also Published As

Publication number Publication date
JP2002501916A (ja) 2002-01-22
EP1051412A1 (en) 2000-11-15
WO1999038859A1 (en) 1999-08-05
BR9907278A (pt) 2000-10-24
CN1314901A (zh) 2001-09-26
BR9908141A (pt) 2000-11-28
ES2178384T3 (es) 2002-12-16
EP1051411A1 (en) 2000-11-15
JP2002501915A (ja) 2002-01-22
ES2207931T3 (es) 2004-06-01
WO1999038860A1 (en) 1999-08-05
US6224717B1 (en) 2001-05-01
MY124273A (en) 2006-06-30
EP1051411B1 (en) 2002-08-28
US6159347A (en) 2000-12-12
EP1051412B1 (en) 2003-09-24
CN1295568A (zh) 2001-05-16

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Owner name: EASTMAN CHEMICAL COMPANY

Free format text: FORMER NAME OR ADDRESS: YISIMAN CHEMICAL COMPANY

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Address after: Tennessee

Patentee after: EASTMAN CHEMICAL Co.

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Granted publication date: 20051005

Termination date: 20100228