CN1217695C - Appetizing promoting digestion oral liquid and the preparation thereof - Google Patents
Appetizing promoting digestion oral liquid and the preparation thereof Download PDFInfo
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- CN1217695C CN1217695C CN 03154237 CN03154237A CN1217695C CN 1217695 C CN1217695 C CN 1217695C CN 03154237 CN03154237 CN 03154237 CN 03154237 A CN03154237 A CN 03154237A CN 1217695 C CN1217695 C CN 1217695C
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Abstract
The present invention discloses an oral liquid for promoting digestion and a preparation method thereof. Diseases caused by failure in transformation of the spleen and the stomach as well as dyspepsia, comprising anepithymia, infantile dyspepsia, anorexia, abdominal distention, diarrhea, vomiting, infantile malnutrition, marasmus and the like, are common pediatric diseases and frequently encountered pediatric diseases. Chinese fevervine, hawthorn, malt, medicated leaven, areca seed, dried tangerine peel and weeping forsythia capsule are used for preparing the oral liquid. The oral liquid has the efficacy for promoting digestion, activating the spleen and improving appetite. Clinical tests prove that the oral liquid can treat pediatric dyspeptic diseases and anorexia of the spleen and the stomach and obviously improve patients' clinical symptoms, and can be used for treating pediatric anorexia.
Description
Technical field
The present invention relates to be a kind of be the Chinese patent medicine of feedstock production with Chinese medicine, specifically a kind of oral liquid with appetite-stimulating indigestion-relieving effect.The invention still further relates to the preparation method of above-mentioned oral liquid.
Background technology
The spleen and stomach in children loses fortune, stop caused anorexia, refusing to eat in the food stagnation, be because improper feeding or eating and drinking without temperance, or due to the long-term monophagia, eating cold and uncooked food excessively, feed variable interval, but the also normal fortune function of impairing the spleen and stomach of above-mentioned situation causes that dysfunction of the spleen in transportation, stomach are not thought to receive, incoordination between the spleen and stomach, thereby produce the anorexia syndrome, card sees, diet is depressed, infantile dyspepsia, anorexia, abdominal distention, have loose bowels, vomiting, infantile malnutrition, become thin, and these have also become the commonly encountered diseases and the frequently-occurring disease of children's's illness.Treatment is whetted the appetite with activating the spleen, and dyspepsia and intestinal stasis relieving is main, controls according to dialectical the executing of the state of an illness clinically, and stomach is transferred in spleen invigorating, when improving clinical symptoms, improves micronutrient levels, improves part and general immunity function, strengthens little intestinal absorption and pancreatin secretory function.Chinese patent medicine commonly used the guarantor is arranged and loose, Anisodus carniolicoides C.Y.Wu et C.Chen, lenitive pill, Health pill etc., though these patent medicine are effective, all be solid dosage formss such as pill, powder or tablet, the child administration inconvenience, big, the heavy bitter taste of flavour of a drug, mouthfeel are poor simultaneously, difficulty is taken.In addition, publication number is 1309983 Chinese invention patent, a kind of Appetizing digestive liquid is disclosed, it is made up of bifidus factor, Endothelium Corneum Gigeriae Galli, Fructus Hordei Germinatus (parched), Fructus Crataegi, Semen Raphani (parched), zinc gluconate, EDTA-ferrum etc., during forming, the raw material of this patent application also has chemical raw material except Chinese medicine, Chinese medicine also is not very clear with the principle that cooperates of chemical raw material, thereby still is to be worth further thinking.
Summary of the invention
Purpose of the present invention is a raw material with Chinese medicine exactly, prepares a kind of oral liquid with appetite-stimulating indigestion-relieving function, demonstrate,proves with the anorexia that treatment the spleen and stomach in children loses due to stopping in fortune, the food stagnation.
Another object of the present invention provides the method for this appetite-stimulating indigestion-relieving oral liquid of preparation.
Technical scheme of the present invention is based on such principle: the infantile anorexia refusing to eat, be because taste lose due to stopping in fortune, the food stagnation, must take dyspepsia and intestinal stasis relieving, invigorating the spleen and benefiting QI, the Therapeutic Principle of the stomach function regulating that helps digestion, circulation of qi promoting removing food stagnancy, activating the spleen appetizing, reasonable formula, the science compatibility is to play the effect of dyspepsia and intestinal stasis relieving, activating the spleen appetizing.For achieving the above object, the present invention has taked such measure: a kind of appetite-stimulating indigestion-relieving oral liquid is prepared from by the following weight proportion raw material:
Herba Paederiae 15-50 part Fructus Crataegi 5-25 part Fructus Hordei Germinatus 5-25 part
Massa Medicata Fermentata 2-10 part Semen Arecae 2-10 part Pericarpium Citri Reticulatae 2-10 part
Fructus Forsythiae 1-5 part;
The preferred weight proportioning of raw material of the present invention is:
Herba Paederiae 20-40 part Fructus Crataegi 5-15 part Fructus Hordei Germinatus 5-15 part
Massa Medicata Fermentata 3-7 part Semen Arecae 5-7 part Pericarpium Citri Reticulatae 3-7 part
Fructus Forsythiae 2-4 part;
The optimum weight proportioning of raw material of the present invention is:
10 parts in 10 parts of Fructus Hordei Germinatus of 25 portions of Fructus Crataegis of Herba Paederiae
5 parts of 5 parts of Pericarpium Citri Reticulataes of 5 portions of Semen Arecaes of Massa Medicata Fermentata
3 parts of Fructus Forsythiaes;
Massa Medicata Fermentata of the present invention records in Guangxi Zhuang Autonomous Region drug standard version in 1993,
Herba Paederiae (Herba Paederiae) records in Chinese Pharmacopoeia version in 1997, and all the other raw materials record on each edition of Chinese Pharmacopoeia.
Preparation method of the present invention comprises the steps:
1, get Massa Medicata Fermentata and soak, heating extraction is collected extracting solution then, filter, filtrate concentrates, and obtaining detecting relative density in the time of 70 ℃ is the concentrated solution of 1.02-1.15, cold after, adding ethanol makes the alcohol amount that contains of concentrated solution be 40-60%, leave standstill, filter filtrate recycling ethanol, and concentrate, the clear paste 1 that obtains detecting relative density and be 1.02-1.15 in the time of 70 ℃ is standby;
2, above-mentioned all the other raw materials are soaked, heating extraction is collected extracting liquid filtering, obtains filtrate, filtrate concentrates, obtaining in the time of 70 ℃ detecting relative density is the concentrated solution of 1.02-1.15, cold after, add ethanol and make the alcohol amount that contains of concentrated solution be 40-60%, leave standstill, filter, filtrate recycling ethanol also concentrates, and the clear paste 2 that obtains detecting relative density and be 1.02-1.15 in the time of 70 ℃ is standby;
3, merge clear paste 1 and clear paste 2, leave standstill, filter, filtrate and simple syrup are mixed with oral liquid, and packing gets final product.
Taking the present invention of above-mentioned measure, is monarch drug with the Herba Paederiae, gets the merit of its dyspepsia and intestinal stasis relieving, invigorating the spleen and benefiting QI; Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata are ministerial drug, get its long-pending effect of stomach function regulating relieving dyspepsia that helps digestion; Because of burnt in the dyspepsia, block mechanism of qi, it is smooth to cause the capable mistake of gas, and Gu Zuo is with Semen Arecae circulation of qi promoting removing food stagnancy; During Pericarpium Citri Reticulatae is regulated the flow of vital energy and is transferred, to help relieving dyspepsia; The easy heat-transformation of food stagnation is so help again with Fructus Forsythiae heat clearing away eliminating stagnation.Above-mentioned all medicines share, and play dyspepsia and intestinal stasis relieving altogether, the effect of activating the spleen appetizing.Show, the effect that promotes mice, rat stomach emptying and mouse small intestine ahead running is arranged with intramuscular administration of the present invention through results of pharmacodynamic test; The effect that promotes mouse small intestine xylose absorption function is arranged; The rat gastric juice of raising and the active effect of pepsin are arranged; Radix Et Rhizoma Rhei is caused " insufficiency of the spleen " young mice, the effect that prolongs its normal pressure hypoxia endurance time and improve its peritoneal macrophage function is arranged; To going on a diet property " deficiency of vital energy " young mice, the effect that promotes its body weight gain and prolong its swimming time is arranged.Clinical test results of the present invention proves, the present invention treats the stagnant card of the spleen and stomach in children apositia clinical efficacy preferably, can obviously improve patient's main clinic symptoms, and has certain promotion infant growth promoter effect, can be used for infantile anorexia, and differential diagnosis in tcm belongs to the stagnant card of taste, and clinical condition is good at the clinical treatment of symptoms such as phase inappetence, anorexia or refusing to eat, food are then glutted, epigastric distension and distress or abdominal distention discomfort, lustreless complexion, body is thin partially, stool acid is smelly.The present invention is an oral liquid formulation, after preparation method preparation of the present invention, has removed the bad smell in the raw material substantially, and mouthfeel is better, has accomplished that good medicine is not bitter to the taste, is fit to child administration more.
The specific embodiment
Embodiment 1
Prescription:
Herba Paederiae 150 Keshan short, bristly hair or beards 50 gram Fructus Hordei Germinatus 50 grams
Massa Medicata Fermentata 20 gram Semen Arecaes 20 gram Pericarpium Citri Reticulataes 20 grams
Fructus Forsythiae 10 grams
Preparation method:
1, get Massa Medicata Fermentata and soaked 10-30 minute, heating extraction twice then, each 1-2 hour, collect extracted twice liquid, filter, filtrate concentrates, obtaining detecting relative density in the time of 70 ℃ is the concentrated solution of 1.02-1.15, after cold, add ethanol make concentrated solution to contain the alcohol amount be 50%, leave standstill, filter, filtrate recycling ethanol, and concentrate, the clear paste 1 that obtains detecting relative density and be 1.02-1.07 in the time of 70 ℃ is standby;
2, above-mentioned all the other raw materials were soaked 1-2 hour, heating extraction twice, each 1-2 hour, collecting extracted twice liquid filters, obtain filtrate, filtrate concentrates, and obtaining detecting relative density in the time of 70 ℃ is the concentrated solution of 1.02-1.07, after cold, add ethanol make concentrated solution to contain the alcohol amount be 50%, leave standstill, filter, filtrate recycling ethanol also concentrates, and the clear paste 2 that obtains detecting relative density and be 1.02-1.15 in the time of 70 ℃ is standby;
3, merge clear paste 1 and clear paste 2, leave standstill, filter, filtrate and simple syrup are mixed with every milliliter and contain the oral liquid that the crude drug amount is the 0.5-0.8 gram, and packing gets final product.
Embodiment 2
Prescription:
Herba Paederiae 500 Keshan short, bristly hair or beards 250 gram Fructus Hordei Germinatus 250 grams
Massa Medicata Fermentata 100 gram Semen Arecaes 100 gram Pericarpium Citri Reticulataes 100 grams
Fructus Forsythiae 50 grams
Preparation method:
Identical with the preparation method of embodiment 1.
Embodiment 3
Prescription:
Herba Paederiae 250 Keshan short, bristly hair or beards 100 gram Fructus Hordei Germinatus 100 grams
Massa Medicata Fermentata 50 gram Semen Arecaes 50 gram Pericarpium Citri Reticulataes 50 grams
Fructus Forsythiae 30 grams
Preparation method:
Identical with embodiment 1 preparation method.
Claims (4)
1, a kind of appetite-stimulating indigestion-relieving oral liquid is characterized in that described oral liquid is prepared from by the following weight proportion raw material:
Herba Paederiae 15-50 part Fructus Crataegi 5-25 part Fructus Hordei Germinatus 5-25 part
Massa Medicata Fermentata 2-10 part Semen Arecae 2-10 part Pericarpium Citri Reticulatae 2-10 part
Fructus Forsythiae 1-5 part.
2, oral liquid according to claim 1 is characterized in that the weight proportion of raw material is:
Herba Paederiae 20-40 part Fructus Crataegi 5-15 part Fructus Hordei Germinatus 5-15 part
Massa Medicata Fermentata 3-7 part Semen Arecae 5-7 part Pericarpium Citri Reticulatae 3-7 part
Fructus Forsythiae 2-4 part.
3, oral liquid according to claim 1 is characterized in that the weight proportion of raw material is:
10 parts in 10 parts of Fructus Hordei Germinatus of 25 portions of Fructus Crataegis of Herba Paederiae
5 parts of 5 parts of Pericarpium Citri Reticulataes of 5 portions of Semen Arecaes of Massa Medicata Fermentata
3 parts of Fructus Forsythiaes.
4, a kind of preparation method of appetite-stimulating indigestion-relieving oral liquid is characterized in that described method comprises the steps:
(1) get Massa Medicata Fermentata and soak, heating extraction is collected extracting solution then, filter, filtrate concentrates, and obtaining detecting relative density in the time of 70 ℃ is the concentrated solution of 1.02-1.15, cold after, adding ethanol makes the alcohol amount that contains of concentrated solution be 40-60%, leave standstill, filter filtrate recycling ethanol, and concentrate, the clear paste 1 that obtains detecting relative density and be 1.02-1.15 in the time of 70 ℃ is standby;
(2) above-mentioned all the other raw materials are soaked, heating extraction is collected extracting liquid filtering, obtains filtrate, filtrate concentrates, obtaining in the time of 70 ℃ detecting relative density is the concentrated solution of 1.02-1.15, cold after, add ethanol and make the alcohol amount that contains of concentrated solution be 40-60%, leave standstill, filter, filtrate recycling ethanol also concentrates, and the clear paste 2 that obtains detecting relative density and be 1.02-1.15 in the time of 70 ℃ is standby;
(3) merge clear paste 1 and clear paste 2, leave standstill, filter, filtrate and simple syrup are mixed with oral liquid, and packing gets final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03154237 CN1217695C (en) | 2003-08-18 | 2003-08-18 | Appetizing promoting digestion oral liquid and the preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03154237 CN1217695C (en) | 2003-08-18 | 2003-08-18 | Appetizing promoting digestion oral liquid and the preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1485085A CN1485085A (en) | 2004-03-31 |
| CN1217695C true CN1217695C (en) | 2005-09-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03154237 Expired - Fee Related CN1217695C (en) | 2003-08-18 | 2003-08-18 | Appetizing promoting digestion oral liquid and the preparation thereof |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893628B (en) * | 2014-03-05 | 2016-08-31 | 青岛农业大学 | A kind of pharmaceutical composition with food digesting action and preparation method thereof |
| CN104256808B (en) * | 2014-08-29 | 2016-01-20 | 广东岭南职业技术学院 | A kind of integration of drinking and medicinal herbs beverage and preparation method thereof |
| CN104367742A (en) * | 2014-11-13 | 2015-02-25 | 成都医路康医学技术服务有限公司 | Traditional Chinese medicine composition containing fructus crataegi and used for treating dyspepsia |
| CN106377709A (en) * | 2016-11-24 | 2017-02-08 | 广西葛洪堂药业有限公司 | Pharmaceutical composition for treating infantile anorexia and malnutrition |
| CN108815425A (en) * | 2018-09-13 | 2018-11-16 | 河南护理职业学院 | A kind of Chinese herbal medicine decoction made from powder agent promoting upgrowth and development of children |
| CN112219992A (en) * | 2019-11-20 | 2021-01-15 | 王秀平 | Stomach-nourishing medicated diet and preparation method thereof |
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2003
- 2003-08-18 CN CN 03154237 patent/CN1217695C/en not_active Expired - Fee Related
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