CN1213550A

CN1213550A - Medicine for treating diabetes and its prepn. method

Info

Publication number: CN1213550A
Application number: CN 97119105
Authority: CN
Inventors: 何立祥
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-10-07
Filing date: 1997-10-07
Publication date: 1999-04-14

Abstract

A medicine for treating diabetes with unique curative effect is prepared from 24 Chinese-medicinal materials such as plantain seed, white tuckahoe, dogwood fruit, siberian solomonseal rhizome, schisandra fruit, etc.

Description

A kind of medicine for the treatment of diabetes and preparation method thereof

The present invention relates to a kind of medicine for the treatment of diabetes, specifically, is a kind of Chinese medicine composition, relates to the preparation method of this medicine in addition.

The medicine of many treatment diabetes known in the state of the art, the Western medicine great majority of for example treating diabetes often make the patient have dependency for insulin type, can not make the patient set up independently homergy circulation, do not have therapeutical effect in fact at all.And the Chinese medicine of existing treatment diabetes can only improve some symptoms of patient, the not remarkable and poor stability of curative effect.

Purpose of the present invention just provides a kind of medicine of evident in efficacy and stable treatment diabetes of pure Chinese medicine.

Another object of the present invention provides the preparation method of this medicine.

It is the active part that raw material adopts conventional extracting method to make that drug main of the present invention will contain the Chinese crude drug of selecting following weight ratio for use: stone chinaberry 20-30, Herba Dianthi 20-30, Semen Plantaginis 20-30, Poria 15-25, Fructus Corni 1-10, Rhizoma Polygonati 20-30, Rhizoma Atractylodis Macrocephalae 15-25, porcine bladder 40-50, Fructus Schisandrae Chinensis 20-30, Periostracum Cicadae 10-20, Rhizoma Anemarrhenae 20-30, Radix Ophiopogonis 20-30, Rhizoma Dioscoreae 55-65, Radix Rehmanniae 55-65, Radix Trichosanthis 20-30, Radix Scrophulariae 25-35, Radix Astragali 25-35, Rhizoma Atractylodis 10-20, Gypsum Fibrosum 100-150, Cordyceps 20-30, Radix Ginseng 20-30, Radix Polygoni Multiflori 20-30, Radix Puerariae 20-30, Radix Salviae Miltiorrhizae 20-30, Fructus Lycii 10-20; Be preferably: stone chinaberry 24, Herba Dianthi 24, Semen Plantaginis 24, Poria 20, Fructus Corni 6, Rhizoma Polygonati 24, Rhizoma Atractylodis Macrocephalae 20, porcine bladder 44, Fructus Schisandrae Chinensis 24, Periostracum Cicadae 12, the Rhizoma Anemarrhenae 24, Radix Ophiopogonis 24, Rhizoma Dioscoreae 60, the Radix Rehmanniae 60, Radix Trichosanthis 24, Radix Scrophulariae 30, the Radix Astragali 30, Rhizoma Atractylodis 12, Gypsum Fibrosum 120, Cordyceps 24, Radix Ginseng 27, Radix Polygoni Multiflori 27, Radix Puerariae 24, Radix Salviae Miltiorrhizae 24, Fructus Lycii 18; Wherein: porcine bladder is preferably dry powder.

Conventional extracting method of the present invention comprises decocting method, infusion process, percolation, reflux extraction, decoction and alcohol sedimentation technique and ethanol extract from water precipitation etc.The used extraction solvent of the present invention comprises water and Different concentrations of alcohol.Extraction time decides according to diverse ways.General decocting method decocting time is 0.5-1.5 hour; Reflux extraction was generally 1-2 hour.

In addition, medicine of the present invention can also be chosen wantonly and contain pharmaceutically acceptable various additives, and these additives comprise filler, binding agent, wetting agent, disintegrating agent, surfactant, lubricant, diluent etc.

According to the present invention, use the conventional formulation technology of this area to make pharmaceutically various preparations to this medicine, the preferred oral administration, wherein representative dosage forms is oral liquid, tablet, unguentum, powder agent, capsule etc.

Medicine of the present invention is progressively stablized curative effect according to the secular clinical experience of inventor, medicine biggest advantage of the present invention is the various staggered compound type that is applicable to diabetes, be not limited to typing, effect with supplementing QI and nourishing YIN, strengthening spleen, tonifying kidney and blood circulation promoting and blood stasis dispelling, various types of diabetes are all had unique curative effect, and cure rate is 50%, total effective rate 90%, and do not have side effect such as dependency, can help making the patient to erect normal metabolic cycles from health is built-in.

Embodiment 11) respectively by following consumption raw materials weighing (unit kilogram): stone chinaberry 24, Herba Dianthi 24, Semen Plantaginis 24, Poria 20, Fructus Corni 6, Rhizoma Polygonati 24, Rhizoma Atractylodis Macrocephalae 20, porcine bladder 44, Fructus Schisandrae Chinensis 24, Periostracum Cicadae 12, the Rhizoma Anemarrhenae 24, Radix Ophiopogonis 24, Rhizoma Dioscoreae 60, the Radix Rehmanniae 60, Radix Trichosanthis 24, Radix Scrophulariae 30, the Radix Astragali 30, Rhizoma Atractylodis 12, Gypsum Fibrosum 120, Cordyceps 24, Radix Ginseng 27, Radix Polygoni Multiflori 27, Radix Puerariae 24, Radix Salviae Miltiorrhizae 24, Fructus Lycii 18; 2) raw material is mixed, add water logging and cross powder, 100 ℃ decocted 1 hour, filtered, and filtrate for later use adds water logging with filtering residue and crosses powder, and 100 ℃ decocted 0.5 hour, filtered merging filtrate; 3) in the filtrate of above-mentioned gained, slowly add ethanol and make and contain the alcohol amount and reach 80%, filter,, obtain active part of the present invention again with decompression filtrate recycling ethanol.Embodiment 2

With the active part drying that obtains among the embodiment 1, pulverized the 80-100 mesh sieve.Adding dry starch 10% mixing, is that wetting agent system soft material is crossed the granulation of 16 mesh sieves with 95% ethanol, dries, and granulate adds magnesium stearate 1%, and mixing is after the calculating sheet is heavy, with 10mm biconvex punch die tabletting, coating.Embodiment 3

With the active part drying that obtains among the embodiment 1, wear into fine powder, incapsulate.

Claims

1. a medicine for the treatment of diabetes is characterized in that it mainly contains the Chinese crude drug of selecting following weight ratio for use is the active part that raw material adopts conventional method to make: stone chinaberry 20-30, Herba Dianthi 20-30, Semen Plantaginis 20-30, Poria 15-25, Fructus Corni 1-10, Rhizoma Polygonati 20-30, Rhizoma Atractylodis Macrocephalae 15-25, porcine bladder 40-50, Fructus Schisandrae Chinensis 20-30, Periostracum Cicadae 10-20, Rhizoma Anemarrhenae 20-30, Radix Ophiopogonis 20-30, Rhizoma Dioscoreae 55-65, Radix Rehmanniae 55-65, Radix Trichosanthis 20-30, Radix Scrophulariae 25-35, Radix Astragali 25-35, Rhizoma Atractylodis 10-20, Gypsum Fibrosum 100-150, Cordyceps 20-30, Radix Ginseng 20-30, Radix Polygoni Multiflori 20-30, Radix Puerariae 20-30, Radix Salviae Miltiorrhizae 20-30, Fructus Lycii 10-20.

2. according to the medicine of claim 1, it is characterized in that it mainly contains the Chinese crude drug of selecting following weight ratio for use is the active part that raw material adopts conventional method to make: stone chinaberry 24, Herba Dianthi 24, Semen Plantaginis 24, Poria 20, Fructus Corni 6, Rhizoma Polygonati 24, Rhizoma Atractylodis Macrocephalae 20, porcine bladder 44, Fructus Schisandrae Chinensis 24, Periostracum Cicadae 12, the Rhizoma Anemarrhenae 24, Radix Ophiopogonis 24, Rhizoma Dioscoreae 60, the Radix Rehmanniae 60, Radix Trichosanthis 24, Radix Scrophulariae 30, the Radix Astragali 30, Rhizoma Atractylodis 12, Gypsum Fibrosum 120, Cordyceps 24, Radix Ginseng 27, Radix Polygoni Multiflori 27, Radix Puerariae 24, Radix Salviae Miltiorrhizae 24, Fructus Lycii 18.

3. according to the medicine of claim 1 or 2, wherein porcine bladder is a dry powder.