CN121057821A - 用于生产3-羟基己二酸、α-氢化己二烯二酸和/或己二酸的基因修饰微生物以及该化学品的制造方法 - Google Patents

用于生产3-羟基己二酸、α-氢化己二烯二酸和/或己二酸的基因修饰微生物以及该化学品的制造方法

Info

Publication number
CN121057821A
CN121057821A CN202480030293.XA CN202480030293A CN121057821A CN 121057821 A CN121057821 A CN 121057821A CN 202480030293 A CN202480030293 A CN 202480030293A CN 121057821 A CN121057821 A CN 121057821A
Authority
CN
China
Prior art keywords
gene
strain
acid
plasmid
genetically modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202480030293.XA
Other languages
English (en)
Chinese (zh)
Inventor
中村仁美
矶部匡平
山田胜成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Publication of CN121057821A publication Critical patent/CN121057821A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN202480030293.XA 2023-05-23 2024-05-22 用于生产3-羟基己二酸、α-氢化己二烯二酸和/或己二酸的基因修饰微生物以及该化学品的制造方法 Pending CN121057821A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2023084247 2023-05-23
JP2023-084247 2023-05-23
PCT/JP2024/018765 WO2024242124A1 (ja) 2023-05-23 2024-05-22 ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Publications (1)

Publication Number Publication Date
CN121057821A true CN121057821A (zh) 2025-12-02

Family

ID=93590034

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202480030293.XA Pending CN121057821A (zh) 2023-05-23 2024-05-22 用于生产3-羟基己二酸、α-氢化己二烯二酸和/或己二酸的基因修饰微生物以及该化学品的制造方法

Country Status (3)

Country Link
JP (1) JPWO2024242124A1 (https=)
CN (1) CN121057821A (https=)
WO (1) WO2024242124A1 (https=)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101023178A (zh) * 2004-09-17 2007-08-22 莱斯大学 高琥珀酸产出细菌
JP5644037B2 (ja) * 2008-02-14 2014-12-24 三菱化学株式会社 ポリアミド樹脂組成物
BR112020010328A2 (pt) * 2017-11-30 2020-11-17 Toray Industries, Inc. micro-organismo geneticamente modificado e métodos de produção de ácido 3-hidroxiadípico, ácido a-hidromucônico e ácido adípico
WO2020230718A1 (ja) * 2019-05-10 2020-11-19 東レ株式会社 ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
EP4245844A4 (en) * 2020-11-11 2025-10-01 Toray Industries GENETICALLY MODIFIED MICROORGANISM FOR THE PRODUCTION OF 3-HYDROXYADIPIC ACID AND/OR ?-HYDROMUCONIC ACID, AND METHOD FOR PRODUCING A CHEMICAL PRODUCT

Also Published As

Publication number Publication date
WO2024242124A1 (ja) 2024-11-28
JPWO2024242124A1 (https=) 2024-11-28

Similar Documents

Publication Publication Date Title
JP7331691B2 (ja) ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
US8778656B2 (en) Organic acid production in microorganisms by combined reductive and oxidative tricaboxylic acid cylce pathways
JP7530554B2 (ja) ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
CN102770550A (zh) 尸胺的制备方法
JP7784060B2 (ja) ３－ヒドロキシアジピン酸および／またはα－ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
CN118591634A (zh) 用于生产3-羟基己二酸和/或α-氢化己二烯二酸的基因修饰微生物以及该化学品的制造方法
WO2023182322A1 (ja) ３－ヒドロキシアジピン酸および／または３－オキソアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
JP7646119B2 (ja) ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
WO2022102635A1 (ja) ３－ヒドロキシアジピン酸および／またはα－ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
US9447439B2 (en) Microorganism producing 4-hydroxybutyrate and a method for producing 4-hydroxybutyrate in anaerobic condition using the same
CN121057821A (zh) 用于生产3-羟基己二酸、α-氢化己二烯二酸和/或己二酸的基因修饰微生物以及该化学品的制造方法
CA3055612A1 (en) Methods and microorganisms for making 1,4-butanediol and derivatives thereof from c1 carbons
EP3257945B1 (en) Recombinant microorganism for diol production
JP7769868B2 (ja) 遺伝子改変微生物および有機酸の製造方法
CN116064346A (zh) 一种高效合成乳糖的方法及其应用
WO2025063258A1 (ja) α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
CN118497167B (zh) 一种l-苏氨酸转醛酶突变体及其在l-对甲砜基苯丝氨酸合成中的应用
WO2022181654A1 (ja) 変異型アシル－ＣｏＡヒドロラーゼ
JP2023144366A (ja) ３－ヒドロキシアジピン酸および／またはα－ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
US20150004661A1 (en) Corynebacterium for producing c4 compounds and method of producing c4 chemicals by using the same
JP2024090463A (ja) ３－ヒドロキシアジピン酸および／またはα－ヒドロムコン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
CN116445379A (zh) N-乙酰氨基葡萄糖6-磷酸脱乙酰酶的失活及其在生产谷氨酸中的应用
CN116144564A (zh) 一种谷氨酸生产菌株的构建方法及其在生产谷氨酸中的用途
KR20240147934A (ko) 1,4-부탄디올 생산용 변이 미생물 및 이를 이용한 1,4-부탄디올의 생산 방법
CN121427780A (zh) 一种利用乙二醇合成丁二酸的大肠杆菌工程菌株及其应用

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination