CN1202364A - Oil solutions for remitting angina pectoris - Google Patents
Oil solutions for remitting angina pectoris Download PDFInfo
- Publication number
- CN1202364A CN1202364A CN 97108105 CN97108105A CN1202364A CN 1202364 A CN1202364 A CN 1202364A CN 97108105 CN97108105 CN 97108105 CN 97108105 A CN97108105 A CN 97108105A CN 1202364 A CN1202364 A CN 1202364A
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- China
- Prior art keywords
- remitting
- angina pectoris
- oleum
- oil solutions
- acori graminei
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Abstract
The oil solution is prepared with Acori graminei, Allium chinense, notoginseng, chili and menthol in certain proportion as main components and through the steps of crushing and alcohol extraction of the first mentioned four materials, mixing the extraction liquid with menthol as well as nitrogen ketone, clove oil, cinnamic oil and turpentine, filtration, packing and disinfection. It is developed based on the Chinese medical theory of treating internal disease through external treatment and the modern transdermal technology and has fast curative effect and no side effect.
Description
The present invention relates to a kind of Chinese medicine preparation.
Obstruction of qi in the chest and cardialgia (coronary heart disease, angina pectoris) is one of clinical common, multiple cardiovascular disease, gives the human physical and mental health very harmful.At present to the treatment of this disease still based on nitric acid lipid, calcium antagonist, B-receptor blocking agent, route of administration comprises intravenously administrable, sublingual administration, oral administration etc., though they have therapeutical effect preferably aspect antianginal, but the side effect of varying degree is all arranged, and prolonged application easily produces drug resistance.The transdermal methods administration is a kind of novel medication that development in recent years is got up, but all with slow release, controlled release and suitable long-acting be its characteristics.Have Chinese medicine for outer use such as unguentum, patch etc. now, all be difficult to reach the effect of quick-acting antalgesic again.
The present invention's purpose aims to provide a kind of according to the traditional Chinese medical science " inner disease outer treat " principle, in conjunction with modern transdermal new technique, through a kind of pure Chinese medicine external novel formulation---the oil solutions for remitting angina pectoris of clinical, experimentation repeatedly, be used for the treatment of angina pectoris, evident in efficacy, have no side effect.
Technical scheme of the present invention is: it is main component that this oil solutions for remitting angina pectoris adopts Rhizoma Acori Graminei, Bulbus Allii Macrostemonis, Radix Notoginseng, Mentholum, Fructus Capsici, by certain percentage by weight proportioning, during making earlier with Rhizoma Acori Graminei, Bulbus Allii Macrostemonis, Radix Notoginseng is cataclasm, use alcohol reflux, obtain extracting solution, again that Fructus Capsici is cataclasm, use alcohol reflux, obtain extracting solution, both extracting solution and PUHE brain are melted with putting to grind altogether altogether in the mortar, and add azone and Oleum Caryophylli, Oleum Cinnamomi, Oleum Terebinthinae, mix homogeneously, filtration, fill, sterilization, promptly.
The present invention is according to the traditional Chinese medical science " inner disease outer treat " principle, and in conjunction with modern transdermal new technique, through clinical, experimentation repeatedly, a kind of pure Chinese medicine external novel formulation that develops, medication uniqueness, prescription are rigorous, and dosage form design novelty, curative effect are rapid, and the medicine source is extensive.The side is a principal agent with the hot temperature fragrance of Rhizoma Acori Graminei, Bulbus Allii Macrostemonis, the logical breast sun of a surname, Flos Magnoliae, Flos Caryophylli, Fructus Capsici, Cortex Cinnamomi, the Radix Angelicae Dahuricae, Rhizoma Atractylodis, is all thick products of abnormal smells from the patient, or the big heat of Da Xin, or fragrant warm-dryness syndrome, to help the hot Wen Xuantong of principal agent; Benefit is with Radix Ginseng Rubra, Radix Notoginseng benefiting QI for activating blood circulation, to control the accompanied symptoms of its blood stasis due to qi deficiency; Many product in the side only with hot Wen Dare, probably it is too high strong, and the Borneolum Syntheticum, Mentholum that are assistant hot cold (cold) be with slow its warm-dryness syndrome too, and Borneolum Syntheticum is kind especially has one's ideas straightened out, and also helps its a surname to lead to.Oleum Terebinthinae, the two figuration of azone are strengthened drug osmotic for making, and speed the logical gesture of a surname.We's Wen Tongxuan numbness, benefiting QI for activating blood circulation, heart arteries and veins mechanism of qi one are smooth, and it is made by oneself bitterly.
Dosage form: externally-applied liniment.
Function: fragrance a surname numbness, blood-activating analgetic.
Main disease to be treated: obstruction of qi in the chest and cardialgia, i.e. angina pectoris.
Usage: be coated with this product 0.1-0.2ml at every turn and put on the skin in the about 6 * 6cm of front skin
2, every day 3 times.Immediately embrocate during angina pectoris attacks, and can smell nose.
Its percentage by weight of above-mentioned main component is: Rhizoma Acori Graminei 10-20%, Bulbus Allii Macrostemonis 10-20%, Radix Notoginseng 7.5-15%, Mentholum 30-55%, Fructus Capsici 10-20%.
In above-mentioned main prescription, also can add Flos Magnoliae, Borneolum Syntheticum, Rhizoma Atractylodis, the Radix Angelicae Dahuricae, Radix Ginseng Rubra becomes the production example prescription, and its percentage by weight is: Rhizoma Acori Graminei 7.5-15%, Bulbus Allii Macrostemonis 7.5-15%, Flos Magnoliae 4.5-9%, Borneolum Syntheticum 7.5-15%, Rhizoma Atractylodis 4.5-9%, Radix Angelicae Dahuricae 7-14%, Radix Ginseng Rubra 4.5-9%, Radix Notoginseng 4.5-9%, Mentholum 20-37.4%, Oleum Caryophylli 1-3%, Oleum Cinnamomi 2-5%, Fructus Capsici 7.5-15%, Oleum Terebinthinae 1-3%, azone 2-6%.
Above-mentioned main prescription and embodiment its preparation technology that writes out a prescription is:
With Rhizoma Acori Graminei, Bulbus Allii Macrostemonis, Rhizoma Atractylodis, the Radix Angelicae Dahuricae, Flos Magnoliae, Radix Ginseng Rubra, Radix Notoginseng is cataclasm one-tenth coarse granule, with 95% alcohol reflux twice, each 2 hours, merge extractive liquid, reclaimed ethanol; Fructus Capsici is cataclasm separately, and with 95% alcohol reflux twice, each 2 hours, merge extractive liquid, reclaimed ethanol; Melt with Borneolum Syntheticum, Mentholum and with putting to grind altogether altogether in the mortar, to there not being coarse granule, and while grinding the adding azone, add Oleum Caryophylli, Oleum Cinnamomi, Oleum Terebinthinae again, fully stir, mix homogeneously is with all medicinal liquid mixings, stir, refilter, in the filtrate filling bottle, the gland of jumping a queue, scalding 30 minutes, promptly.
Claims (4)
1, a kind of oil solutions for remitting angina pectoris, it is characterized in that adopting Rhizoma Acori Graminei, Bulbus Allii Macrostemonis, Radix Notoginseng, Mentholum, Fructus Capsici is main component, by certain percentage by weight proportioning, during making earlier with Rhizoma Acori Graminei, Bulbus Allii Macrostemonis, Radix Notoginseng is cataclasm, use alcohol reflux, obtain extracting solution, again that Fructus Capsici is cataclasm, use alcohol reflux, obtain extracting solution, both extracting solution and PUHE brain are melted with putting to grind altogether altogether in the mortar, and add azone and Oleum Caryophylli, Oleum Cinnamomi, Oleum Terebinthinae, mix homogeneously, filtration, fill, sterilization, promptly.
2, oil solutions for remitting angina pectoris according to claim 1 is characterized in that described certain percentage by weight proportioning is: Rhizoma Acori Graminei 10-20%, Bulbus Allii Macrostemonis 10-20%, Radix Notoginseng 7.5-15%, Mentholum 30-55%, Fructus Capsici 10-20%.
3, oil solutions for remitting angina pectoris according to claim 1 is characterized in that also can adding Flos Magnoliae, Borneolum Syntheticum, Rhizoma Atractylodis, the Radix Angelicae Dahuricae, Radix Ginseng Rubra.
4, oil solutions for remitting angina pectoris according to claim 1 is characterized in that the percentage by weight proportioning is: Rhizoma Acori Graminei 7.5-15%, Bulbus Allii Macrostemonis 7.5-15%, Flos Magnoliae 4.5-9%, Borneolum Syntheticum 7.5-15%, Rhizoma Atractylodis 4.5-9%, Radix Angelicae Dahuricae 7-14%, Radix Ginseng Rubra 4.5-9%, Radix Notoginseng 4.5-9%, Mentholum 20-37.4%, Oleum Caryophylli 1-3%, Oleum Cinnamomi 2-5%, Fructus Capsici 7.5-15%, Oleum Terebinthinae 1-3%, azone 2-6%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97108105 CN1202364A (en) | 1997-06-13 | 1997-06-13 | Oil solutions for remitting angina pectoris |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97108105 CN1202364A (en) | 1997-06-13 | 1997-06-13 | Oil solutions for remitting angina pectoris |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1202364A true CN1202364A (en) | 1998-12-23 |
Family
ID=5170133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97108105 Pending CN1202364A (en) | 1997-06-13 | 1997-06-13 | Oil solutions for remitting angina pectoris |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1202364A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1793690A1 (en) * | 2004-06-09 | 2007-06-13 | Purimed Co., Ltd. | Acorus gramineus soland extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same |
| WO2010127411A1 (en) * | 2009-05-08 | 2010-11-11 | Allmedic Pty Ltd | Treatment of pain and/or inflammation and treatment and prevention of a skin or mucosal disease and/or condition |
| CN101843753B (en) * | 2009-12-09 | 2011-07-20 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating angina |
| CN108310314A (en) * | 2018-03-06 | 2018-07-24 | 杭州益寿生物医药科技有限公司 | A kind of composition of plant extracts for analgesic |
-
1997
- 1997-06-13 CN CN 97108105 patent/CN1202364A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1793690A1 (en) * | 2004-06-09 | 2007-06-13 | Purimed Co., Ltd. | Acorus gramineus soland extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same |
| JP2008501788A (en) * | 2004-06-09 | 2008-01-24 | ピュリメド カンパニー リミテッド | Ishizuchi extract for prevention or treatment of ischemic heart disease, pharmaceutical composition containing the same and health food |
| EP1793690A4 (en) * | 2004-06-09 | 2009-07-29 | Purimed Co Ltd | Acorus gramineus soland extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same |
| WO2010127411A1 (en) * | 2009-05-08 | 2010-11-11 | Allmedic Pty Ltd | Treatment of pain and/or inflammation and treatment and prevention of a skin or mucosal disease and/or condition |
| AU2010244983B2 (en) * | 2009-05-08 | 2015-07-16 | Allmedic Pty Ltd | Treatment of pain and/or inflammation and treatment and prevention of a skin or mucosal disease and/or condition |
| CN101843753B (en) * | 2009-12-09 | 2011-07-20 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating angina |
| CN108310314A (en) * | 2018-03-06 | 2018-07-24 | 杭州益寿生物医药科技有限公司 | A kind of composition of plant extracts for analgesic |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |