CN1251669C - Acne removing and skin rejuvenating cream - Google Patents

Acne removing and skin rejuvenating cream Download PDF

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Publication number
CN1251669C
CN1251669C CNB2004100450692A CN200410045069A CN1251669C CN 1251669 C CN1251669 C CN 1251669C CN B2004100450692 A CNB2004100450692 A CN B2004100450692A CN 200410045069 A CN200410045069 A CN 200410045069A CN 1251669 C CN1251669 C CN 1251669C
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portions
group
acne
ointment base
proportion
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CNB2004100450692A
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CN1593610A (en
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李洲平
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Abstract

The present invention relates to a cosmetic, particularly to an acne-removing and skin-rejuvenating cream for treating comedos and acne, which is characterized in that the acne-removing and skin-rejuvenating cream is prepared from a prescription group, a perfuming agent group and an ointment base group of the proportion by weight: 10 to 40 portions of the prescription group, 1 to 2.5 portions of the perfuming agent group and 57.5 to 89 portions of the ointment base group, wherein the prescription group comprises the components of the proportion by weight: 1.6 to 6.4 portions of honeysuckle flower, 1.2 to 4.8 portions of weeping forsythia capsule, 1.2 to 4.8 portions of wild chrysanthemum, 1.2 to 4.8 portions of dandelion, 0.8 to 3.2 portions of prepared fankincense, 0.8 to 3.2 portions of prepared myrrh, 0.8 to 3.2 portions of philippine violet herb, 0.8 to 3.2 portions of semiaquilegia root, 0.4 to 1.6 portions of saute Chinese honeylocust spine, 0.4 to 1.6 portions of thunberg fritillary bulb, 0.4 to 1.6 portions of liquorice and 0.4 to 1.6 portions of stir-fried pangolin scale; the perfuming agent group comprises the component of the proportion by weight: 1.0 to 2.5 portions of camphor; the ointment base group comprises the component of the proportion by weight: 57.5 to 89 portions of polyethyleneglycol. The acne-removing and skin-rejuvenating cream has the advantages of convenient use, portability and high cure rate.

Description

A kind of ointment for the treatment of acne and acne
Technical field
The present invention relates to a kind of cosmetics, particularly a kind of ointment for the treatment of acne and acne.
Background technology
Acne, acne are the diseases that influence common among the young crowd is improved looks, the sickness rate height.The cosmetics and the medicine of treatment acne, acne are wide in variety at present, but cure rate is undesirable.
Traditional Chinese medical science name one's elder is also dissatisfied according to " Xian fang Huoming Yin " or " wuwei xiaodu drink " in Golden Mirror of Medicine plus-minus oral medication acne, the acne effect of " married woman's good recipe is annotated in the school " lining.
Xian fang Huoming Yin prescription: the Radix Angelicae Dahuricae, Bulbus Fritillariae Uninbracteatae, Radix Saposhnikoviae, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Radix Glycyrrhizae uralensis, stir-fry Spina Gleditsiae, Squama Manis (processed), Radix Trichosanthis, Olibanum, each 1 money of Myrrha, Flos Lonicerae, each 3 money of Pericarpium Citri Reticulatae.
Wuwei xiaodu drink prescription: Flos Lonicerae 3 money, Flos Chrysanthemi Indici, Herba Taraxaci, Herba Violae, each 1 money of Radix Semiaquilegiae 2 minutes.
More than two sides be the name side of the Gu, modern usage all water to take juice oral, every day, potion divided secondary oral.Decocting time is shorter, and general about each about 30 minutes, active ingredient was extracted not exclusively, makes some active ingredient destroyed through the gastrointestinal complex environment again, so therapeutic effect is dissatisfied, and the waste medical material.
Summary of the invention
Purpose of the present invention just provides the high a kind of ointment for the treatment of acne and acne of cure rate, with solve present acne, acne is shown effect repeatedly, the problem that is difficult to cure.
Technical scheme of the present invention realizes that by following approach it is formulated according to a certain ratio by square medicine group, aromatic group and ointment base group, and their weight proportion is:
Side medicine group 10-40 part
Aromatic group 1-2.5 part
Ointment base group 57.5-89 part
Wherein: a) component of square medicine group and weight proportion are: Flos Lonicerae 1.6-6.4 part, Fructus Forsythiae, Flos Chrysanthemi Indici, each 1.2-4.8 part of Herba Taraxaci, Olibanum (processed), Myrrha (processed), Herba Violae, each 0.8-3.2 part of Radix Semiaquilegiae are fried Spina Gleditsiae, gradually Bulbus Fritillariae Uninbracteatae, Radix Glycyrrhizae, each 0.4-1.6 part of Squama Manis (processed); B) component of aromatic group and weight proportion are: Camphora 1.0-2.5 part; C) the ointment base group is a Polyethylene Glycol, and its weight proportion is 57.5-89 part.
The present invention is according to " wuwei xiaodu drink " and " Xian fang Huoming Yin " two sides prescription again, deducted the medicine that obvious warm-dryness syndrome effect is arranged and be not suitable for external, changed its medication ratio, and added the new drug of heat-clearing and toxic substances removing and the medicine of causing resuscitation with aromatic drugs effect, increased the Transdermal absorption ability of medicine.The present invention has also changed extracting method, reduced the loss of active ingredient, changed route of administration, oral decoction has been made externally-applied soft ointment directly act on the affected part, and selected the water-soluble ointment base of no greasy, made pH value and be about 5.5 ointment.The present invention's use, easy to carry, the cure rate height, and saved crude drug, and economical and practical, extraordinary social benefit and economic benefit are arranged.
The present invention treats acne vulgaris 128 examples between year March in March, 2000-2003, matched group is with 1% clindamycin hydrochloride gel external, and 3 times/day, and oral tetracycline tablet 0.25g, 4 times/day, 4 weeks were a course of treatment, observed result after 1-2 course of therapy.
Case is divided into two groups, and 128 examples are organized in treatment: male's 78 examples, women's 50 examples; Age 13-33 year; Course of disease 1-15; Typing: I type 25 examples, II type 40 examples, III type 34 examples, IV29 example.Matched group 125 examples: male's 70 examples, women's 55 examples; Age 12-29 year; Course of disease 1-14; Typing: I type 23 examples, II type 38 examples, III type 32 examples, IV32 example.Learn processing by statistics for two groups, sex, age, the course of disease, typing all do not have significant difference (P>0.05).
Diagnostic criteria: with reference to Japanese plum Lay, Bai Yijie chief editor " cosmetic dermatology " (Jiangxi publishing house of colleges and universities, 1999:127), about the diagnostic criteria of ordinary base sore.
Typing standard: with reference to " acne typing opinion is controlled " (Chinese journal of dermatology, 2002,1: typing standard 67) of Jin Peiying.
Criterion of cure: conscious clinical symptom disappearance, pimple, pustule, acne, tuberosity counting are 0.
The result: treatment group cure rate 93.75%, matched group cure rate 8% is through x 2Check, X 2=27.653, P<0.005, treatment group cure rate significantly is better than matched group.
The specific embodiment
Describe the specific embodiment of the present invention below in detail.
The present invention is formulated according to a certain ratio by square medicine group, aromatic group and ointment base group, and their weight proportion is:
Side medicine group 10-40 part
Aromatic group 1-2.5 part
Ointment base group 57.5-89 part
Wherein, a) component of square medicine group and weight proportion are: Flos Lonicerae 1.6-6.4 part, Fructus Forsythiae, Flos Chrysanthemi Indici, each 1.2-4.8 part of Herba Taraxaci, Olibanum (processed), Myrrha (processed), Herba Violae, each 0.8-3.2 part of Radix Semiaquilegiae are fried Spina Gleditsiae, gradually Bulbus Fritillariae Uninbracteatae, Radix Glycyrrhizae, each 0.4-1.6 part of Squama Manis (processed); B) component of aromatic group and weight proportion are: Camphora 1.0-2.5 part, add a small amount of 99.7% ethanol; C) the ointment base group is a Polyethylene Glycol, and its weight proportion is 57.5-89 part.
A specific embodiment of the present invention is (is example to prepare 1000 gram ointment):
Side's medicine group 350 grams
Aromatic group 10 grams
Ointment base group 640 grams
Wherein, a) component of square medicine group and weight proportion are: Flos Lonicerae 56g, and Fructus Forsythiae, Flos Chrysanthemi Indici, each 42g of Herba Taraxaci, Olibanum (processed), Myrrha (processed), Herba Violae, each 28g of Radix Semiaquilegiae fry Spina Gleditsiae, gradually Bulbus Fritillariae Uninbracteatae, Radix Glycyrrhizae, each 14g of Squama Manis (processed); B) component of aromatic group and weight proportion are: Camphora 10 gram adds a small amount of 99.7% ethanol and wears into smalls (no granular sensation) and get final product; C) PEG (Polyethylene Glycol) 4000, each equivalent of PEG400 are heated to 65 ℃ and stir evenly in water-bath, become ointment base 640g after the condensation.
Manufacture method:
By the above-mentioned consumption side of taking by weighing medicine group medicine 350g, add cold water 3500g merceration 15 minutes, boil after 1 hour and filter with 100 mesh sieves; Medicinal residues add 2800g cold water again and boil after 30 minutes sealing, 80 ℃ of warm macerating of constant temperature after 4 hours with the filtration of 100 mesh sieves (in the process of boiling with warm macerating, will constantly stir); Medicinal residues filter with 100 mesh sieves after squeezing out remaining medicine juice; 3 times filtrate is blended in cryoconcentration to 1 between 60-70 ℃: 1 (mass ratio, be that the 1g concentrated medicine juice is equivalent to the 1g crude drug) after, get concentrated medicine juice 350g, add among the ointment base 640g and stir evenly, add aromatic group Camphora smalls 10g again and stir evenly, promptly make a kind of ointment for the treatment of acne and acne of 1000g light brown.

Claims (1)

1, a kind of ointment for the treatment of acne and acne, it is formulated according to a certain ratio by square medicine group, aromatic group and ointment base group, it is characterized in that their weight proportion is:
Side medicine group 10-40 part
Aromatic group 1-2.5 part
Ointment base group 57.5-89 part
Wherein:
A) component of square medicine group and weight proportion are: Flos Lonicerae 1.6-6.4 part, Fructus Forsythiae, Flos Chrysanthemi Indici, each 1.2-4.8 part of Herba Taraxaci, Olibanum (processed), Myrrha (processed), Herba Violae, each 0.8-3.2 part of Radix Semiaquilegiae are fried Spina Gleditsiae, gradually Bulbus Fritillariae Uninbracteatae, Radix Glycyrrhizae, each 0.4-1.6 part of Squama Manis (processed);
B) component of aromatic group and weight proportion are: Camphora 1.0-2.5 part;
C) the ointment base group is a Polyethylene Glycol, and its weight proportion is 57.5-89 part.
CNB2004100450692A 2004-07-15 2004-07-15 Acne removing and skin rejuvenating cream Expired - Fee Related CN1251669C (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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CN1593610A CN1593610A (en) 2005-03-16
CN1251669C true CN1251669C (en) 2006-04-19

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101301368B (en) * 2008-06-13 2012-01-04 孟承伟 Medicinal liquor for treating comedo

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105250488A (en) * 2015-11-15 2016-01-20 衡阳市金凤牲猪养殖专业合作社 Drug for preventing and treating pig skin disease and preparation method thereof
CN109731053A (en) * 2018-12-29 2019-05-10 广州市紫松贸易有限公司 A kind of Chinese medicine composition that treating dark sore or whelk, paste and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101301368B (en) * 2008-06-13 2012-01-04 孟承伟 Medicinal liquor for treating comedo

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