CN119968460A - 用于在不存在细胞外基质的条件下培养类器官的药物 - Google Patents

用于在不存在细胞外基质的条件下培养类器官的药物 Download PDF

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Publication number
CN119968460A
CN119968460A CN202380068690.1A CN202380068690A CN119968460A CN 119968460 A CN119968460 A CN 119968460A CN 202380068690 A CN202380068690 A CN 202380068690A CN 119968460 A CN119968460 A CN 119968460A
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organoid
organoids
absence
extracellular matrix
matrigel
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Chinese (zh)
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佐藤俊朗
矢野智树
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Keio School
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Keio School
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • A—HUMAN NECESSITIES
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    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N9/10—Transferases (2.)
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11001—Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase

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CN202380068690.1A 2022-09-27 2023-09-27 用于在不存在细胞外基质的条件下培养类器官的药物 Pending CN119968460A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2022153698 2022-09-27
JP2022-153698 2022-09-27
JP2023-090460 2023-05-31
JP2023090460 2023-05-31
PCT/JP2023/035181 WO2024071212A1 (ja) 2022-09-27 2023-09-27 細胞外基質の非存在下でオルガノイドを培養するための薬剤

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CN119968460A true CN119968460A (zh) 2025-05-09

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CN202380068690.1A Pending CN119968460A (zh) 2022-09-27 2023-09-27 用于在不存在细胞外基质的条件下培养类器官的药物

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US (1) US20250283049A1 (https=)
EP (1) EP4596677A1 (https=)
JP (1) JPWO2024071212A1 (https=)
CN (1) CN119968460A (https=)
WO (1) WO2024071212A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025211257A1 (ja) * 2024-04-01 2025-10-09 慶應義塾 オルガノイド製造用培地及びその使用
CN118697877A (zh) * 2024-05-27 2024-09-27 复旦大学 Yap通路激活剂在制备抗嗜肝病毒药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6662518B2 (ja) 2015-04-09 2020-03-11 国立大学法人 東京医科歯科大学 腸上皮間リンパ球をインビトロで維持・増殖させる方法
EP3350313B1 (en) * 2015-09-15 2025-11-26 Agency For Science, Technology And Research (A*star) Derivation of liver organoids from human pluripotent stem cells
GB201819224D0 (en) * 2018-11-26 2019-01-09 Koninklijke Nederlandse Akademie Van Wetenschappen Hepatocyte expansion methods
CN113348017A (zh) * 2019-01-30 2021-09-03 日产化学株式会社 酰肼化合物及激酶抑制剂
JP7676361B2 (ja) * 2019-08-13 2025-05-14 チルドレンズ ホスピタル メディカル センター オルガノイド組成物を作製するための改良された方法
JP7594960B2 (ja) 2021-03-30 2024-12-05 ＪＤＩ Ｄｅｓｉｇｎ ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ 合同会社 半導体装置、表示装置、及び半導体装置の製造方法
JP7769973B2 (ja) 2021-12-17 2025-11-14 パナソニックＩｐマネジメント株式会社 配線器具

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JPWO2024071212A1 (https=) 2024-04-04
EP4596677A1 (en) 2025-08-06
WO2024071212A1 (ja) 2024-04-04
US20250283049A1 (en) 2025-09-11

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