CN1197667A - Externally used medicine for hepatitis B - Google Patents

Abstract

The said medicine is prepared with Resina Draconis, asafoetida, conceretio silicea bambbusae, Semen brassicae, croton and other Chinese medicinal materials by compounding in certain proprotion, grinding into powder and mixing with breast milk into paste. It is dressed at liver region and has high curative effect on hepatitis B and no toxic side effect.

Description

A kind of medicine for external use for the treatment of hepatitis B

The invention belongs to a kind of medicine for external use that forms by prepared from traditional Chinese medicines, a kind of specifically medicine for external use for the treatment of hepatitis B.

The people that hepatitis B is suffered from by China is a lot, has 1/10th people to have hepatitis B virus approximately.Hepatitis B system is by due to the hepatitis B virus, and main per os, blood transfusion and injecting pathway infect.Motherland's Chinese medicine thinks that the primary disease polyphyly is damp and hot, and due to the irritability stasis of blood was long-pending, primary disease belonged to the category of damp and hot and costalgia.Liver cirrhosis is common and malnutrition, infection (as viral hepatitis, parasitic infection), (as ethanol, drug intoxication) the relevant chronic diffusivity hepatic disease of poisoning, its pathological change is hepatocellular degeneration, necrosis and liver cell regeneration, proliferation of fibrous tissue, the liver structure disturbance, so that portal hypertension and hypofunction of liver take place, even depleted, genus motherland Chinese medicine " is splashed and is risen ", the category of " lump in the abdomen ", and it is dirty relevant with liver,spleen,kidney three that development takes place for it.Medical circle is thought a kind of pertinacious disease that is difficult to effect a radical cure.In treatment the traditional Chinese medical science mainly adopt oral Chinese medicine as: Tarragon Tonga flavor, Artemisia anethoicles Mattf WULING SAN add flavor, Artemisia anethoicles Mattf stomach Siberian cocklebur Tonga subtracts; Or with bupleurum powder for relieving liver-qi plus-minus, XIAOYAO POWDER is closed the decoction of four noble drugs plus-minus, and the Radix Salviae Miltiorrhizae drink closes prescriptions such as Sichuan Chinaberry Powder plus-minus, takes this class decoction, need take for a long time, makes troubles and painful to the patient; Western medical treatment mainly adopts nutrition and supporting treatment, hypertonic glucose, Vc, glucuronolatone, motassium magnessium aspartate etc., or the injection anti-interferon etc., this method effect is not good yet.

The object of the present invention is to provide a kind of medicine for external use of the treatment hepatitis B that forms by prepared from traditional Chinese medicines, be attached to Zhangmen, point lr 14 scope; Duplicating of blocking hepatitis B virus can be repaired hepatocyte and regeneration effect effectively, reaches the purpose of treatment hepatitis B.

Solution of the present invention is based on motherland's medical science to pathogenetic understanding of hepatitis B and Therapeutic Principle, with reference to modern pharmacological research, select blood circulation promoting and blood stasis dispelling, diuretic for use, carry poison in going into, decompose subcutaneous fat, go the swollen pain that disappears, deeply reach class drug development such as table and form, can activate liver cell regeneration, downright bad hepatocyte is brought back to life, reach the purpose of treatment hepatitis B.

The present invention is a medicine for external use, and is formulated by pure Chinese medicine, so without any side effects to human body.

The present invention is made up of the following weight proportion raw material: Sanguis Draxonis 60-90, Resina Ferulae 60-150, Concretio Silicea Bambusae 50-80, Semen Sinapis Albae 50-80, Fructus Crotonis 50-80, Moschus 2-3, Squama Manis 50-80, Scolopendra 50-70, Hirudo 50-60, human milk 400-500.

After the present invention adopted above scheme, the treatment hepatitis B had significant curative effect, effective percentage 92%, and cure rate reaches 77%, and it is rapid to remove hepatitis B symptom, has no side effect, easy to use.

Below in conjunction with embodiment the present invention is described in detail.

Blood-activating stasis-removing kind Chinese medicine is among the present invention: Sanguis Draxonis, Moschus, Squama Manis, Hirudo.

Dewatering class medicine is: Fructus Crotonis.

Carrying malicious class medicine in going into is: Moschus, Resina Ferulae, Concretio Silicea Bambusae.

Decomposing the subcutaneous fat medicine is: Semen Sinapis Albae.

Go the swollen pain class Chinese medicine that disappears to be: Scolopendra, Semen Sinapis Albae, Resina Ferulae, Sanguis Draxonis.

Drug action mechanism of the present invention is as follows:

Sanguis Draxonis: go into conscience warp, clots absorbing pain relieving, arresting bleeding and healing up ulcer granulation promoting (see " simple and clear Chinese medicine dictionary " 320 pages, in March, 1979, the People's Health Publisher published); Clots absorbing pain relieving, promoting tissue regeneration and ulcer healing (see " the Chinese medicine pharmacology of Chinese medical formulae " 804 pages, in February, 1972, Shandong College of Traditional Chinese Medicine's prescription Zhou Feng of teaching and research room realized the chief editor).

Resina Ferulae: hot, tepor; Function cures mainly: removing food stagnancy, parasite killing are used for abdominal mass.Hepatosplenomegaly, gastral cavity abdomen, cold type of pain, malnutrition due to parasitic infestation meat amass, and go into plaster external (see " Pharmacopoea Chinensis " 308 pages, published first one in 1977, Pharmacopoeia of People's Republic of China committee compiles, and the People's Health Publisher publishes) more; Slightly warm in nature, acrid in the mouth, removing food stagnancy, parasite killing, detoxifcation (see " science of identification of Chinese materia medica " 532 pages, Science and Technology of Shanghai publishing house publishes, the Ren Renan chief editor).

Concretio Silicea Bambusae: property: sweet, cold, GUIXIN, liver, gallbladder meridian, the transconversion into heat expectorant that disappears, the arresting convulsion of the cool heart, remove fresh breeze heat, relieving palpitation, make eye bright, control skin ulcer (seeing " simple and clear Chinese medicine dictionary " the 111st page).

Semen Sinapis Albae: Xin Wen, go into lung, stomach warp, promoting the circulation of QI eliminating phlegm, warming stomach for dispelling cold, removing obstruction in the collateral to relieve pain eliminating stagnation, subside a swelling, control the carbuncle of yin nature sucutaneous nodule (seeing " simple and clear Chinese medicine dictionary " 249 pages).

Fructus Crotonis: hot, hot, very toxic, return stomach, large intestine, lung meridian, rushing down cold down long-pendingly by the capable water of expectorant, cure mainly malignant boil and see (seeing " simple and clear Chinese medicine dictionary " 210 pages).

Drastic purgation detumescent, dispelling phlegm and relieving sore-throat, the phagedenoma pain that disappears of amassing, relieve oedema or abdominal distension through diuresis or purgation.

Function cures mainly: the drastic purgation detumescence that stagnates, relieves oedema or abdominal distension through diuresis or purgation.Be used for cold long-pending stagnation, chest and abdomen swelling and pain, edema, acute throat trouble, external treatment skin ulcer tinea, nevus verrucosus (" seeing Pharmacopoea Chinensis " 123 pages).

Warmly rush down long-pending, disappear subsides, detoxifcation of relieving oedema or abdominal distension through diuresis or purgation and treat skin ulcer (seeing " science of prescription " 347 pages).

Moschus: hot, temperature, go into the heart, spleen, Liver Channel; Have one's ideas straightened out, ward off dirty, blood circulation promoting and dispersing pathogen accumulation.Have one's ideas straightened out refresh oneself, promoting blood circulation and detumescence, stimulating the menstrual flow reaches network; Cure mainly the calentura coma, the apoplexy syncope due to accumulation of phlegm, infantile convulsion, attacked by pestiferous factors, trusted subordinate's sudden pain are controlled mass in the abdomen and are gathered, traumatic injury, cellulitis toxic swelling (seeing " simple and clear Chinese medicine dictionary " 1002 pages).

Squama Manis: lightly seasoned, property is flat, gas raw meat and scurrying, and its property of walking to scurry is very careful, leads to internal organs so can declare, and implements meridians, reaches the pass key thoroughly, and all blood clottings, blood gather all can open it.To control the disease pain, use it boldly and with confidence, produce immediate results.The kind lump in the abdomen (see " Records of Tradition Chinese and Western Medicine in Combination ", the new medical university in Hebei in May nineteen fifty-seven learns and publishes Zhang Xichen, salt hill chief editor) of controlling.

Scolopendra: distinguish the flavor of little suffering, slightly warm in nature.Walk the play steepest, interior and internal organs, outer and meridians, all QI and blood cohesion part all can be opened it.The little poison of performance, and change kind detoxifcation, all poison of all skin infection all can disappear it; Its property is kind especially searches wind, and the treatment by oral administration of medicines liver-wind is sprouted, external treatment skin ulcer first (seeing " Records of Tradition Chinese and Western Medicine in Combination ").

Hirudo: salty in the mouth, darkish complexion, gas corruption, property are put down.Be its salty in the mouth, thus be apt to into blood system, for its originally for biting the thing of blood, so kind removing blood stasis, its abnormal smells from the patient is moved and inspired mutually with blood stasis, does not does not move and inspire mutually with fresh blood, but removing blood stasis with potent drugs blood and do not hinder fresh blood, removing blood stasis with potent drugs blood is the intuitive ability of this thing, and blood stasis is write from memory and disappeared in invisible, cures mainly the disease of lump in the abdomen.

Human milk: have effects such as the Fructus Crotonis of elimination, Semen Sinapis Albae, chafe, bonding medicine.

All medicines synthesize blood circulation promoting and blood stasis dispelling, diuretic, carry poison in going into, decompose subcutaneous fat, go swollen sterilization, deeply reach table, can activate liver cell regeneration, and downright bad hepatocyte is brought back to life, and reach the purpose for the treatment of hepatitis B.

For showing therapeutic effect of the present invention, get 70 example ages, sexes, case history, patient that the state of an illness is different, lose money in a business medicine respectively once according to conditions of patients, the observation period is 8 days, stopped for two weeks after, lose money in a business medicine more once, be viewed as 8 days again; And then stop the back subsides of two weeks once, be a course of treatment.Sx, what still need treat is effectively; Transference cure through 5 index inspections of liver function, reaches the serum HBsAg negative patient and is recovery from illness.

Basic condition is illustrated by following table:

Table 1 test group basic condition table:

Table 2 test group therapeutic effect table:

Embodiment 1: get Sanguis Draxonis 60g, Resina Ferulae 70g, Concretio Silicea Bambusae 50g, Semen Sinapis Albae 55g, Fructus Crotonis 50g, Squama Manis 50g, Scolopendra 50g, Hirudo 50g, with above 8 flavor Chinese medicine pulverizations, cross dusting cover, mix thoroughly, get this mixed-powder, with human milk 450g furnishing pasty state, above then Moschus 2.5g evenly being sprinkling upon, be affixed on Zhangmen, point lr 14 scope, take off after 4 hours, 1-5 ℃ of preservation pasted continuously after 8 days and stopped pasting two weeks, use the same method again, renew medicament, pasting twice again is a course of treatment, and the treatment hepatitis B can be fully recovered; Utmost point severe patient was used with two courses of treatment of quadrat method manifold card, reached the purpose of curing hepatitis B.

Example 2: get Sanguis Draxonis 70g, Resina Ferulae 150, Concretio Silicea Bambusae 55g, Semen Sinapis Albae 50g, Fructus Crotonis 52g, Squama Manis 65g, Scolopendra 65g, Hirudo 58g, with above 8 flavor Chinese medicine pulverizations, cross dusting cover, mix thoroughly, get this mix powder, with human milk 500g furnishing pasty state, above then Moschus 3g evenly being sprinkling upon, using method is with example 1, treating hepatocirrhosis ascites.

Claims (3)

1. the medicine for external use of treatment hepatitis B is characterized in that it is the medicine of being made by the following weight proportion raw material, with human milk furnishing pasty state, sprinkle Moschus and be affixed on Zhangmen, point lr 14 scope: Sanguis Draxonis 60-90, Resina Ferulae 60-150, Concretio Silicea Bambusae 50-80, Semen Sinapis Albae 50-80, Fructus Crotonis 50-80, Moschus 2-3, Squama Manis 50-80, Scolopendra 50-70, Hirudo 50-60, human milk 450-500.

2. the medicine for external use of treatment hepatitis B according to claim 1, wherein the weight proportion of each raw material is: Sanguis Draxonis 60, Resina Ferulae 70, Concretio Silicea Bambusae 50, Semen Sinapis Albae 55, Fructus Crotonis 50, Moschus 2.5, Squama Manis 50, Scolopendra 50, Hirudo 50, human milk 450.

3. the medicine for external use of treatment hepatitis B according to claim 1, wherein the weight proportion of each raw material is: Sanguis Draxonis 70, Resina Ferulae 150, Concretio Silicea Bambusae 55, Semen Sinapis Albae 50, Fructus Crotonis 52, Moschus 3, Squama Manis 65, Scolopendra 65, Hirudo 58, human milk 500.