CN1196475C - 异维甲酸的生物可利用剂型 - Google Patents

异维甲酸的生物可利用剂型 Download PDF

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Publication number
CN1196475C
CN1196475C CNB018024173A CN01802417A CN1196475C CN 1196475 C CN1196475 C CN 1196475C CN B018024173 A CNB018024173 A CN B018024173A CN 01802417 A CN01802417 A CN 01802417A CN 1196475 C CN1196475 C CN 1196475C
Authority
CN
China
Prior art keywords
acid
microns
less
particle size
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB018024173A
Other languages
English (en)
Chinese (zh)
Other versions
CN1388757A (zh
Inventor
A·潘特
I·巴蒂亚
S·B·罗伊
R·马立克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CN1388757A publication Critical patent/CN1388757A/zh
Application granted granted Critical
Publication of CN1196475C publication Critical patent/CN1196475C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB018024173A 2000-06-16 2001-04-09 异维甲酸的生物可利用剂型 Expired - Fee Related CN1196475C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN596DE2000 IN192188B (cg-RX-API-DMAC7.html) 2000-06-16 2000-06-16
IN596/DEL/00 2000-06-16

Publications (2)

Publication Number Publication Date
CN1388757A CN1388757A (zh) 2003-01-01
CN1196475C true CN1196475C (zh) 2005-04-13

Family

ID=11097063

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018024173A Expired - Fee Related CN1196475C (zh) 2000-06-16 2001-04-09 异维甲酸的生物可利用剂型

Country Status (25)

Country Link
US (1) US6740337B2 (cg-RX-API-DMAC7.html)
EP (1) EP1294357A1 (cg-RX-API-DMAC7.html)
JP (1) JP2004503493A (cg-RX-API-DMAC7.html)
CN (1) CN1196475C (cg-RX-API-DMAC7.html)
AP (1) AP2002002423A0 (cg-RX-API-DMAC7.html)
AU (1) AU782094B2 (cg-RX-API-DMAC7.html)
BG (1) BG106414A (cg-RX-API-DMAC7.html)
BR (1) BR0106752A (cg-RX-API-DMAC7.html)
CA (1) CA2382065A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ2002694A3 (cg-RX-API-DMAC7.html)
EA (1) EA004808B1 (cg-RX-API-DMAC7.html)
EE (1) EE200200074A (cg-RX-API-DMAC7.html)
HK (1) HK1052302A1 (cg-RX-API-DMAC7.html)
HR (1) HRP20020148A2 (cg-RX-API-DMAC7.html)
HU (1) HUP0203717A3 (cg-RX-API-DMAC7.html)
IL (1) IL148176A0 (cg-RX-API-DMAC7.html)
IN (1) IN192188B (cg-RX-API-DMAC7.html)
MX (1) MXPA02001669A (cg-RX-API-DMAC7.html)
NZ (1) NZ517142A (cg-RX-API-DMAC7.html)
OA (1) OA12008A (cg-RX-API-DMAC7.html)
PL (1) PL352838A1 (cg-RX-API-DMAC7.html)
SK (1) SK2252002A3 (cg-RX-API-DMAC7.html)
UA (1) UA74793C2 (cg-RX-API-DMAC7.html)
WO (1) WO2001095886A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200201240B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001289438A1 (en) * 2000-09-22 2002-04-02 Galephar M/F Pharmaceutical semi-solid composition of isotretinoin
EP1527774A1 (en) 2003-11-03 2005-05-04 Basilea Pharmaceutica AG New formulation for retinoid-containing soft gelatin capsules
BRPI0410646A (pt) * 2003-05-20 2006-07-04 Ranbaxy Lab Ltd composições farmacêuticas de acitretina e processo para sua preparação
US20070254025A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Oral contraceptive and acne medication combination and treatment of acne with reduced side effects
US20070254858A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects
RU2322998C1 (ru) * 2006-11-16 2008-04-27 Общество с ограниченной ответственностью "Березовый мир" Носитель лекарственных и диагностических средств
CN101610754A (zh) * 2007-02-16 2009-12-23 Aska制药株式会社 含有微粒油性混悬液的药物组合物
WO2008102375A2 (en) * 2007-02-20 2008-08-28 Ipca Laboratories Limited A process for preparation of highly pure isotretinoin
US9078925B2 (en) 2012-06-18 2015-07-14 Galephar Pharmaceutical Research, Inc. Pharmaceutical semi-solid composition of isotretinoin
BR112017025427A2 (pt) * 2015-05-25 2018-08-07 Sun Pharmaceutical Ind Ltd composição farmacêutica oral
US10517846B2 (en) 2016-05-26 2019-12-31 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for treating acne

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016254A (en) * 1972-05-19 1977-04-05 Beecham Group Limited Pharmaceutical formulations
CA1282326C (en) * 1984-12-14 1991-04-02 Paul J. Jarosz Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
US4808630A (en) * 1987-01-16 1989-02-28 United States Of America Method of treating psychotic illnesses
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
PE20001227A1 (es) 1998-10-30 2000-11-06 Hoffmann La Roche Procesos para producir una composicion de isotretinoina
US6284283B1 (en) * 1999-10-21 2001-09-04 Alkermes Controlled Therapeutics, Inc. Method of producing sub-micron particles of biologically active agents and uses thereof

Also Published As

Publication number Publication date
EP1294357A1 (en) 2003-03-26
BG106414A (en) 2002-09-30
CA2382065A1 (en) 2001-12-20
EA004808B1 (ru) 2004-08-26
HRP20020148A2 (en) 2003-12-31
US20020025338A1 (en) 2002-02-28
AU4445901A (en) 2001-12-24
HUP0203717A2 (hu) 2003-04-28
MXPA02001669A (es) 2002-08-06
NZ517142A (en) 2003-08-29
CZ2002694A3 (cs) 2002-08-14
BR0106752A (pt) 2002-04-16
IN192188B (cg-RX-API-DMAC7.html) 2004-03-13
JP2004503493A (ja) 2004-02-05
ZA200201240B (en) 2002-09-02
HUP0203717A3 (en) 2003-05-28
UA74793C2 (en) 2006-02-15
CN1388757A (zh) 2003-01-01
EA200200166A1 (ru) 2002-10-31
IL148176A0 (en) 2002-09-12
AP2002002423A0 (en) 2002-03-31
HK1052302A1 (zh) 2003-09-11
PL352838A1 (en) 2003-09-08
US6740337B2 (en) 2004-05-25
SK2252002A3 (en) 2002-08-06
AU782094B2 (en) 2005-06-30
EE200200074A (et) 2003-04-15
WO2001095886A1 (en) 2001-12-20
OA12008A (en) 2006-04-19

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