CN119523986A - 伊马替尼在治疗中风中的用途 - Google Patents

伊马替尼在治疗中风中的用途 Download PDF

Info

Publication number
CN119523986A
CN119523986A CN202411509669.3A CN202411509669A CN119523986A CN 119523986 A CN119523986 A CN 119523986A CN 202411509669 A CN202411509669 A CN 202411509669A CN 119523986 A CN119523986 A CN 119523986A
Authority
CN
China
Prior art keywords
imatinib
day
administered
dose
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202411509669.3A
Other languages
English (en)
Chinese (zh)
Inventor
乌尔夫·埃里克森
尼尔斯·贡纳尔·瓦尔格伦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brain Consultant Nils Gunnar Wahlgren AB
Hamra Invest AB
Original Assignee
Brain Consultant Nils Gunnar Wahlgren AB
Hamra Invest AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brain Consultant Nils Gunnar Wahlgren AB, Hamra Invest AB filed Critical Brain Consultant Nils Gunnar Wahlgren AB
Publication of CN119523986A publication Critical patent/CN119523986A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN202411509669.3A 2016-02-29 2017-02-27 伊马替尼在治疗中风中的用途 Pending CN119523986A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE1650260A SE539450C2 (en) 2016-02-29 2016-02-29 Imatinib for use in the treatment of stroke
SE1650260-1 2016-02-29
CN201780013732.6A CN108697711A (zh) 2016-02-29 2017-02-27 伊马替尼在治疗中风中的用途
PCT/SE2017/050183 WO2017151043A1 (en) 2016-02-29 2017-02-27 Imatinib for use in the treatment of stroke

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780013732.6A Division CN108697711A (zh) 2016-02-29 2017-02-27 伊马替尼在治疗中风中的用途

Publications (1)

Publication Number Publication Date
CN119523986A true CN119523986A (zh) 2025-02-28

Family

ID=59744327

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202411509669.3A Pending CN119523986A (zh) 2016-02-29 2017-02-27 伊马替尼在治疗中风中的用途
CN201780013732.6A Pending CN108697711A (zh) 2016-02-29 2017-02-27 伊马替尼在治疗中风中的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201780013732.6A Pending CN108697711A (zh) 2016-02-29 2017-02-27 伊马替尼在治疗中风中的用途

Country Status (17)

Country Link
US (2) US10953010B2 (enExample)
EP (1) EP3423060B1 (enExample)
JP (1) JP6914957B2 (enExample)
CN (2) CN119523986A (enExample)
AU (1) AU2017227515B2 (enExample)
DK (1) DK3423060T3 (enExample)
ES (1) ES2895432T3 (enExample)
HR (1) HRP20211621T1 (enExample)
HU (1) HUE056798T2 (enExample)
LT (1) LT3423060T (enExample)
PL (1) PL3423060T3 (enExample)
PT (1) PT3423060T (enExample)
RS (1) RS62465B1 (enExample)
RU (1) RU2739382C1 (enExample)
SE (1) SE539450C2 (enExample)
SI (1) SI3423060T1 (enExample)
WO (1) WO2017151043A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10617756B2 (en) * 2017-01-05 2020-04-14 Shimojani, LLC Drug regimen for treatment of cerebral ischemia
CN114306342B (zh) * 2020-09-30 2024-06-28 江苏先声药业有限公司 一种注射用伊马替尼盐的药物组合物及其制备方法
CN118524852A (zh) * 2021-11-09 2024-08-20 真和制药有限公司 治疗或抑制心血管疾病的方法
EP4311539A1 (en) 2022-07-29 2024-01-31 Artorange Ltd. Imatinib formulation for parenteral administration
US20250000934A1 (en) 2023-06-28 2025-01-02 Pharmazz, Inc. Lyophilized sovateltide-based injectable formulation and method for preparation thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148074A (en) * 2005-05-10 2013-02-28 Novartis Ag Pharmaceutical compositions comprising imatinib and a release retardant
EP2021028A2 (en) 2006-04-17 2009-02-11 Ludwig Institute For Cancer Research Methods and compositions for modulation of blood-neural barrier
US7977348B2 (en) * 2006-04-27 2011-07-12 Sicor Inc. Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form α
EP2076507A2 (en) * 2006-10-26 2009-07-08 Sicor, Inc. Imatinib base, and imatinib mesylate and processes for preparation thereof
US20100136094A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for modulating inflammation
TR201911199T4 (tr) * 2009-03-27 2019-08-21 Moleac Pte Ltd Hücre büyümesini arttırmak için tedavi.

Also Published As

Publication number Publication date
PT3423060T (pt) 2021-10-20
RS62465B1 (sr) 2021-11-30
AU2017227515B2 (en) 2022-03-24
ES2895432T3 (es) 2022-02-21
JP2019507165A (ja) 2019-03-14
SE539450C2 (en) 2017-09-26
LT3423060T (lt) 2021-11-10
CN108697711A (zh) 2018-10-23
RU2739382C1 (ru) 2020-12-23
JP6914957B2 (ja) 2021-08-04
EP3423060B1 (en) 2021-07-21
US10953010B2 (en) 2021-03-23
DK3423060T3 (da) 2021-10-25
SE1650260A1 (en) 2017-08-30
WO2017151043A1 (en) 2017-09-08
AU2017227515A1 (en) 2018-08-30
EP3423060A1 (en) 2019-01-09
SI3423060T1 (sl) 2021-11-30
US20210236488A1 (en) 2021-08-05
HUE056798T2 (hu) 2022-03-28
EP3423060A4 (en) 2020-01-01
US20190030030A1 (en) 2019-01-31
PL3423060T3 (pl) 2022-01-10
HRP20211621T1 (hr) 2022-02-04

Similar Documents

Publication Publication Date Title
US20210236488A1 (en) Imatinib for use in the treatment of stroke
Diringer et al. Aneurysmal subarachnoid hemorrhage: strategies for preventing vasospasm in the intensive care unit
JP6208235B2 (ja) 多発性硬化症治療のためのビオチンの使用
US20220133629A1 (en) Formulations for treatment of dry eye disease
US20210186990A1 (en) Methods and compositions for treating various disorders
US20110319384A1 (en) Pharmaceutical Compositions
KR20240162094A (ko) 미르다메티닙 치료
Awad et al. Dabigatran, intracranial hemorrhage, and the neurosurgeon
WO2019210836A1 (zh) 一种联合用药物及其在制备治疗术后复发标准治疗无效的高级别脑瘤的药物中的用途
JP2020511535A (ja) 中枢神経系(cns)がんを治療するためのプロテアソーム阻害剤の利用
US20190224208A1 (en) Pharmaceutical composition for treating premature ejaculation and method for treating premature ejaculation
Jiyanboyevich et al. The Comparison between management versus percutaneous coronary intervention (PCI) patients with coronary artery disease (CAD)
Bello et al. Central nervous system stimulants and drugs that suppress appetite
TW202342049A (zh) 治療患有腦損傷的患者的方法以及增加患有腦損傷的患者的擴展版格拉斯哥結局量表的值的方法
KR20250114057A (ko) 맥관 기형용 의약 조성물 및 맥관 기형의 치료 방법
WO2022147318A1 (en) Methods of treatment
DiGiulio Kidney Cancer: Study Sheds Light on Partial vs. Full Nephrectomy Debate
Kramer et al. Status epilepticus
Wang et al. Sublingual Cilostazol and Dexborneol for the Treatment of Acute Ischaemic Stroke: A Phase 2, Randomised, Double-Blind, Double-Dummy, Placebo-Controlled, Multicentre Trial

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination