CN119256073A - 细胞移动装置 - Google Patents
细胞移动装置 Download PDFInfo
- Publication number
- CN119256073A CN119256073A CN202280096390.XA CN202280096390A CN119256073A CN 119256073 A CN119256073 A CN 119256073A CN 202280096390 A CN202280096390 A CN 202280096390A CN 119256073 A CN119256073 A CN 119256073A
- Authority
- CN
- China
- Prior art keywords
- container
- suction
- cells
- cell
- head
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000012292 cell migration Effects 0.000 title claims 9
- 230000007246 mechanism Effects 0.000 claims abstract description 27
- 230000009471 action Effects 0.000 claims abstract description 9
- 230000005859 cell recognition Effects 0.000 claims abstract description 4
- 230000033001 locomotion Effects 0.000 claims description 31
- 238000007599 discharging Methods 0.000 claims description 22
- 238000011156 evaluation Methods 0.000 claims description 8
- 238000002347 injection Methods 0.000 claims description 8
- 239000007924 injection Substances 0.000 claims description 8
- 230000009087 cell motility Effects 0.000 abstract description 18
- 210000004027 cell Anatomy 0.000 description 356
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical group OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 23
- 238000012545 processing Methods 0.000 description 18
- 238000012546 transfer Methods 0.000 description 18
- 239000002609 medium Substances 0.000 description 16
- 239000007788 liquid Substances 0.000 description 15
- 238000003384 imaging method Methods 0.000 description 11
- 238000010586 diagram Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 230000004308 accommodation Effects 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 238000004113 cell culture Methods 0.000 description 5
- 238000012790 confirmation Methods 0.000 description 5
- 239000011159 matrix material Substances 0.000 description 5
- 244000181917 Rubus leucodermis Species 0.000 description 4
- 235000011036 Rubus leucodermis Nutrition 0.000 description 4
- 235000003942 Rubus occidentalis Nutrition 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 230000002093 peripheral effect Effects 0.000 description 4
- 238000004891 communication Methods 0.000 description 3
- 238000005286 illumination Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000002203 pretreatment Methods 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 241000252212 Danio rerio Species 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000006143 cell culture medium Substances 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 239000011796 hollow space material Substances 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000010801 machine learning Methods 0.000 description 1
- 210000002220 organoid Anatomy 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
- C12M33/06—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles for multiple inoculation or multiple collection of samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2022/021920 WO2023233464A1 (ja) | 2022-05-30 | 2022-05-30 | 細胞移動装置 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN119256073A true CN119256073A (zh) | 2025-01-03 |
Family
ID=89025922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280096390.XA Pending CN119256073A (zh) | 2022-05-30 | 2022-05-30 | 细胞移动装置 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP4512884A1 (https=) |
| JP (1) | JP7780009B2 (https=) |
| CN (1) | CN119256073A (https=) |
| WO (1) | WO2023233464A1 (https=) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2933625A4 (en) | 2012-12-13 | 2015-12-02 | Yamaha Motor Co Ltd | SUCTION TIP, OBJECT OBSERVATION DEVICE WITH THE SAID TIP AND METHOD FOR OBSERVING AN OBJECT |
| JP6450476B2 (ja) | 2015-12-25 | 2019-01-09 | ヤマハ発動機株式会社 | 対象物移動方法及び装置 |
| US11572537B2 (en) * | 2017-04-20 | 2023-02-07 | Yamaha Hatsudoki Kabushiki Kaisha | Cell handling device |
| JP6841903B2 (ja) * | 2017-04-20 | 2021-03-10 | ヤマハ発動機株式会社 | 細胞移動装置及び細胞移動方法 |
| CN114127255B (zh) * | 2019-07-26 | 2024-12-13 | 株式会社岛津制作所 | 细胞拾取装置 |
-
2022
- 2022-05-30 WO PCT/JP2022/021920 patent/WO2023233464A1/ja not_active Ceased
- 2022-05-30 EP EP22944051.6A patent/EP4512884A1/en active Pending
- 2022-05-30 JP JP2024524527A patent/JP7780009B2/ja active Active
- 2022-05-30 CN CN202280096390.XA patent/CN119256073A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4512884A1 (en) | 2025-02-26 |
| WO2023233464A1 (ja) | 2023-12-07 |
| JPWO2023233464A1 (https=) | 2023-12-07 |
| JP7780009B2 (ja) | 2025-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |