CN1192369A

CN1192369A - Medicine for treating cirrhosis

Info

Publication number: CN1192369A
Application number: CN98105026A
Authority: CN
Inventors: 孟福厚
Original assignee: Individual
Current assignee: Individual
Priority date: 1998-01-25
Filing date: 1998-01-25
Publication date: 1998-09-09

Abstract

The present invention discloses a kind of traditional Chinese medicine for treating liver cirrhosis, it consists of root of membranousmilk vetch, capillary artemisia, root of red-rooted salvia, unpeeled root of herbaceous peony, arrowhead etc. 19 traditional Chinese medicinal herbs and is made into concentrated pills or capsules or powder etc. Chinese proprietary medicine through the ordinary traditional Chinese medicinal prepn. method. Said medicine can prolong the survival rate of patients of cancer of liver and ascites due to liver cirrhosis about 3-10 years.

Description

A kind of medicine for the treatment of liver cirrhosis

The present invention relates to a kind of Chinese medicine medicine for the treatment of liver cirrhosis.

Cirrhosis is a common frdquently encountered disease clinically after the hepatitis, is to cause the principal element of sending out canceration of hepatic cell.At present, whole world pathogenesis of cirrhosis rate is 2.5～3.5%, there is every year the people more than 400,000 to die from portal hypertension syndrome (upper gastrointestinal hemorrhage and/or ascites), also accounts for more than 4.5% of internal medicine number of hospitalized, and be the trend that increases year by year at the sickness rate of China's liver cirrhosis.Now the treatment of primary disease still there is not breakthrough.Main medicine, as: inosine, glucuronolatone, albumin, cellular energy mixture, compound amino acid supplement etc., still unsatisfactory to the cure rate and the alleviation complication that improve liver cirrhosis, treatment to cirrhotic ascites is corrected measures such as water salt through bed, limit sodium, spironolactone, diuretic, albumin, success rate only is 60%, acts on of short duration.

Reflecting to do has the problem that exists in the Drug therapy liver cirrhosis now, the purpose of this invention is to provide the Chinese medicine medicine of a kind of antiviral and the interior fibrosis of inhibition liver, mediation microcirculation, enhancing body immunity, minimizing alleviation liver cirrhosis.

Chinese medicine medicine of the present invention is made up of 19 flavor Chinese medicines such as the Radix Astragali, ZANGYINCHEN, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, the Rhizoma Atractylodis Macrocephalae, Carapax Trionycis pearl, Rhizoma sagittariae sagittifoliae, OYSTER EXTRACT CAPSULE, Rhizoma Polygoni Cuspidati, Polyporus, long-pending reality, Rhizoma Cyperi, Radix Angelicae Sinensis, Radix Bupleuri, Semen Persicae, Colla Corii Asini, eupolyphaga, stir-fry Semen Pharbitidis, Radix Et Rhizoma Rhei (parched).

Pharmaceutical compositions of the present invention forms (weight ratio) scope: black ugly 1.8～2.7% rhubarb,torrefieds, 0.9～2.7% each the component summation of the Radix Astragali 5.3～16.0% Tibetan oriental wormwoods, 5.3～16.0% reds sage root 5.3～13.3% radix paeoniae rubrathe, 2.7～13.3% bighead atractylodes rhizomes 5.3～10.7% turtle shell pearls, 5.3～10.7% arrowheads 5.3～10.7% OYSTER EXTRACT CAPSULEs, 5.3～10.7% giant knotweeds 5.3～10.7% umbellate pore furgus, 2.7～5.3% long-pending real 2.7～5.3% rhizoma cyperis 2.7～5.3% Radix Angelicae Sinensis, 1.8～5.3% radix bupleuri 1.8～2.7% peach kernels, 1.8～2.7% donkey-hide gelatin 1.8～2.7% soil units, 1.8～2.7% stir-frys is 100%.

The optimal drug composition forms (weight ratio): black 2.0～2.5% rhubarb,torrefieds, 1.5～2.0% each the component summation of the Radix Astragali 8.6～12.6% Tibetan oriental wormwoods, 8.6～12.6% reds sage root 7.0～11.0% radix paeoniae rubrathe, 6.0～9.0% bighead atractylodes rhizomes 6.5～9.5% turtle shell pearls, 6.5～9.5% arrowheads 6.5～9.5% OYSTER EXTRACT CAPSULEs, 6.5～9.5% giant knotweeds 6.5～9.5% umbellate pore furgus, 3.5～4.5% long-pending real 3.5～4.5% rhizoma cyperis 3.5～4.5% Radix Angelicae Sinensis, 3.2～4.0% radix bupleuri 2.0～2.5% peach kernels, 2.0～2.5% donkey-hide gelatin 2.0～2.5% soil units, 2.0～2.5% stir-frys are 100%.

Use the prescription of drug component of the present invention, adopt common Chinese medicine processing method and preparation process, can be made into Chinese patent medicines such as concentrated pill, capsule and electuary.

Use medicine of the present invention to use clinically, give full play to the comprehensive function of each component of Chinese medicine medicine, on effect, demonstrate unique polytropism and indication widely, to improving and adjusting body's immunity and suppress liver inner cellulose hypertrophy, improve the circulation of liver inner blood, prevent hepatic necrosis, promote hepatocellular reparation and regeneration, make the liver and spleen retraction of enlargement, ascites is ended development and is eliminated, and has played good effect.Take through clinical 58 routine cirrhotic ascites patients, effective percentage to liver, splenomegaly is respectively 88.6% and 90.6%, in vain, globulin (A/G) ratio inversion rate is 92.8%, portal hypertension syndrome (upper gastrointestinal hemorrhage and/or ascites) effective percentage is 100%, it is fast to fall enzyme (GPT), can end pathological development effectively, improves General Symptoms, find that through the CT check this medicine has the distinguished service of stronger inhibition hepatoma carcinoma cell disintegrate fragmentation, so can be used for the treatment of hepatocarcinoma.Use this medicine, the survival rate of cirrhotic ascites and liver cancer patient was improved 3～10 years, life quality is obviously improved.

Embodiment: carrying out concentrated pill of the present invention when producing, its compound method is, each component drug is cleaned, and it is qualified all to concoct, and weighs by recipe ingredient and assorts; Crushing screening then; Through liquor (except that Carapax Trionycis pearl and Colla Corii Asini), leaching medicinal liquid; Add Carapax Trionycis pearl fine powder and donkey-hide gelatin fine powder again and mix, be condensed into ball, cold drying, polishing, it is stand-by to bottle.

Claims

1, a kind of by the Radix Astragali, ZANGYINCHEN, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, the Carapax Trionycis pearl, Rhizoma sagittariae sagittifoliae, OYSTER EXTRACT CAPSULE, Rhizoma Polygoni Cuspidati, Polyporus, long-pending real, Rhizoma Cyperi, Radix Angelicae Sinensis, Radix Bupleuri, Semen Persicae, Colla Corii Asini, eupolyphaga, fry the Chinese medicine medicine of the treatment liver cirrhosis of Semen Pharbitidis and Radix Et Rhizoma Rhei (parched) composition, it is characterized in that the component composition (weight ratio) of this medicine is: the summation that the Radix Astragali 5.3～16.0% ZANGYINCHEN 5.3～16.0% Radix Salviae Miltiorrhizaes 5.3～13.3% Radix Paeoniae Rubra 2.7～13.3% Rhizoma Atractylodis Macrocephalaes 5.3～10.7% Carapax Trionycis pearls 5.3～10.7% Rhizoma sagittariae sagittifoliaes 5.3～10.7% OYSTER EXTRACT CAPSULE 5.3～10.7% Rhizoma Polygoni Cuspidati 5.3～10.7% Polyporus 2.7～5.3% long-pending real 2.7～5.3% Rhizoma Cyperis, 2.7～5.3% Radix Angelicae Sinensis, 1.8～5.3% Radix Bupleuri, 1.8～2.7% Semen Persicaes, 1.8～2.7% Colla Corii Asini, 1.8～2.7% eupolyphaga 1.8～2.7% are fried Semen Pharbitidis 1.8～2.7% Radix Et Rhizoma Rhei (parched) 0.9～2.7% each component is 100%.

2, the Chinese medicine for the treatment of cirrhosis according to claim 1 is characterized in that this medicine contains (weight ratio): black ugly 2.0～2.5% rhubarb,torrefieds, 1.5～2.1% each the component summation of the Radix Astragali 8.6～12.6% Tibetan oriental wormwoods, 8.6～12.6% reds sage root 7.0～11.0% radix paeoniae rubrathe, 6.0～9.0% bighead atractylodes rhizomes 6.5～9.5% turtle shell pearls, 6.5～9.5% arrowheads 6.5～9.5% OYSTER EXTRACT CAPSULEs, 6.5～9.5% giant knotweeds 6.5～9.5% umbellate pore furgus, 3.5～4.5% long-pending real 3.5～4.5% rhizoma cyperis 3.5～4.5% Radix Angelicae Sinensis, 3.2～4.0% radix bupleuri 2.0～2.5% peach kernels, 2.0～2.5% donkey-hide gelatin 2.0～2.5% soil units, 2.0～2.5% stir-frys are 100%.