CN119072326A - 用于预防和/或治疗由SARS-CoV-2引起的感染的化合物 - Google Patents

用于预防和/或治疗由SARS-CoV-2引起的感染的化合物 Download PDF

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Publication number
CN119072326A
CN119072326A CN202380017328.1A CN202380017328A CN119072326A CN 119072326 A CN119072326 A CN 119072326A CN 202380017328 A CN202380017328 A CN 202380017328A CN 119072326 A CN119072326 A CN 119072326A
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CN
China
Prior art keywords
cov
sars
oph
viral
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380017328.1A
Other languages
English (en)
Chinese (zh)
Inventor
M·拉福吉
P·格雷森斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Western Dais Paris, University of
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Western Dais Paris, University of
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Western Dais Paris, University of, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Western Dais Paris, University of
Publication of CN119072326A publication Critical patent/CN119072326A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
CN202380017328.1A 2022-01-24 2023-01-19 用于预防和/或治疗由SARS-CoV-2引起的感染的化合物 Pending CN119072326A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22305072.5 2022-01-24
EP22305072 2022-01-24
PCT/EP2023/051296 WO2023139182A1 (en) 2022-01-24 2023-01-19 Compound for use in preventing and/or treating an infection caused by sars-cov-2

Publications (1)

Publication Number Publication Date
CN119072326A true CN119072326A (zh) 2024-12-03

Family

ID=80446266

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380017328.1A Pending CN119072326A (zh) 2022-01-24 2023-01-19 用于预防和/或治疗由SARS-CoV-2引起的感染的化合物

Country Status (6)

Country Link
US (1) US20250099530A1 (https=)
EP (1) EP4469073A1 (https=)
JP (1) JP2025504519A (https=)
KR (1) KR20240139056A (https=)
CN (1) CN119072326A (https=)
WO (1) WO2023139182A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2923160B1 (fr) 2007-11-02 2013-07-26 Pasteur Institut Composes destines a prevenir ou traiter une infection virale.
WO2021228846A1 (en) 2020-05-11 2021-11-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) Compound for preventing or treating a viral infection
WO2022008597A1 (en) * 2020-07-08 2022-01-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical composition for the treatment of infectious diseases
WO2022123062A1 (en) * 2020-12-11 2022-06-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Blocking caspase and/or fasl for preventing fatal outcome in covid-19 patients

Also Published As

Publication number Publication date
EP4469073A1 (en) 2024-12-04
WO2023139182A1 (en) 2023-07-27
JP2025504519A (ja) 2025-02-12
US20250099530A1 (en) 2025-03-27
KR20240139056A (ko) 2024-09-20

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