CN118804758A - Serpin肽及其使用方法 - Google Patents

Serpin肽及其使用方法 Download PDF

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Publication number
CN118804758A
CN118804758A CN202280092284.4A CN202280092284A CN118804758A CN 118804758 A CN118804758 A CN 118804758A CN 202280092284 A CN202280092284 A CN 202280092284A CN 118804758 A CN118804758 A CN 118804758A
Authority
CN
China
Prior art keywords
seq
serpin
disease
serpin peptide
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280092284.4A
Other languages
English (en)
Chinese (zh)
Inventor
达纳·奥斯汀
C·格伯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SERPIN PHARMA LLC
Original Assignee
SERPIN PHARMA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SERPIN PHARMA LLC filed Critical SERPIN PHARMA LLC
Publication of CN118804758A publication Critical patent/CN118804758A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN202280092284.4A 2022-01-05 2022-12-30 Serpin肽及其使用方法 Pending CN118804758A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263266444P 2022-01-05 2022-01-05
US63/266,444 2022-01-05
PCT/US2022/082669 WO2023133078A2 (en) 2022-01-05 2022-12-30 Serpin peptides and methods of using the same

Publications (1)

Publication Number Publication Date
CN118804758A true CN118804758A (zh) 2024-10-18

Family

ID=87074167

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280092284.4A Pending CN118804758A (zh) 2022-01-05 2022-12-30 Serpin肽及其使用方法

Country Status (8)

Country Link
US (2) US20250161419A1 (https=)
EP (1) EP4460322A4 (https=)
JP (1) JP2025503607A (https=)
CN (1) CN118804758A (https=)
AU (1) AU2022431253A1 (https=)
CA (1) CA3247129A1 (https=)
IL (1) IL314135A (https=)
WO (1) WO2023133078A2 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017040287A1 (en) * 2015-08-28 2017-03-09 Serpin Pharma, Llc Methods for treatment of diseases
WO2017123401A1 (en) * 2016-01-13 2017-07-20 Children's Hospital Medical Center Compositions and methods for treating allergic inflammatory conditions
EP3773727A4 (en) * 2018-04-09 2022-05-04 Yale University BIFUNCTIONAL SMALL MOLECULES TO TARGETING THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS
KR20220099963A (ko) * 2019-10-10 2022-07-14 예일 유니버시티 세포 수용체를 통한 분자 분해제로서의 조작된 항체
US20210162029A1 (en) * 2019-11-04 2021-06-03 Azitra Inc Compositions and methods for treatment or prevention of skin diseases and disorders with lekti
EP4003391A4 (en) * 2020-07-06 2023-02-22 Serpin Pharma, LLC PEPTIDES AND METHODS OF USE THEREOF
AU2022222778A1 (en) * 2021-02-22 2023-08-31 Yale University Targeted bifunctional degraders and methods using same

Also Published As

Publication number Publication date
US20230406906A1 (en) 2023-12-21
AU2022431253A1 (en) 2024-07-25
WO2023133078A2 (en) 2023-07-13
CA3247129A1 (en) 2023-07-13
EP4460322A2 (en) 2024-11-13
US20250161419A1 (en) 2025-05-22
IL314135A (en) 2024-09-01
JP2025503607A (ja) 2025-02-04
EP4460322A4 (en) 2026-02-25
WO2023133078A3 (en) 2023-08-17

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