CN118403113A - Traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation - Google Patents

Traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation Download PDF

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CN118403113A
CN118403113A CN202410537998.2A CN202410537998A CN118403113A CN 118403113 A CN118403113 A CN 118403113A CN 202410537998 A CN202410537998 A CN 202410537998A CN 118403113 A CN118403113 A CN 118403113A
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traditional chinese
chinese medicine
medicine composition
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毛廷丽
蒋宛凌
胡玉琳
王忠全
唐羽
吴孟珊
贺小波
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Chongqing emergency medical center
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Chongqing emergency medical center
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Abstract

The application discloses a traditional Chinese medicine composition for treating swelling after fracture operation and joint movement limitation in the field of traditional Chinese medicines, which comprises the following components in parts by weight: 3-5 parts of raw radix aconiti, 3-5 parts of raw kusnezoff monkshood root, 3-5 parts of raw arisaema tuber, 5-10 parts of raw pollen typhae, 5-10 parts of frankincense, 5-10 parts of myrrh, 3-5 parts of safflower, 3-5 parts of red paeony root, 5-10 parts of raw rhubarb, 5-10 parts of beautiful sweetgum fruit, 5-10 parts of pubescent angelica root, 5-10 parts of drynaria rhizome, 1-3 parts of moxibustion licorice and 1-3 parts of honey. The traditional Chinese medicine composition has obvious effects of detumescence, analgesia, stasis removal and vein relaxing for swelling and joint dysfunction after fracture operation; grinding the above materials (except Mel) into superfine powder at a fixed ratio, heating vaseline, stirring, adding quantitative Mel, and making into ointment for topical application. The traditional Chinese medicine composition is suitable for patients with swelling and limited joint movement after fracture operation.

Description

Traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation.
Background
With the high popularization of vehicles and the development of sports, the incidence of fracture is rising year by year, and in addition, with the aging of population, the incidence of osteoporosis and osteoporotic fracture is steadily rising in recent years. To promote healing of the fracture, reduce the occurrence of sequelae, fracture patients, particularly fractures of the joints of the extremities, often require surgical treatment. For displaced adult limb fractures with surgical indications, incision reduction internal fixation is the most common and preferred treatment for the surgeon. However, the fracture and the operation can generate trauma to the human body, and the vascular and lymphatic vessels are damaged, so that the vascular permeability is changed, the venous and lymphatic reflux is hindered, and simultaneously, the fracture is accompanied with inflammatory reaction which the fracture healing organism must experience, so that the patient still has local swelling after the fracture operation. And the local swelling soft tissue can press the blood vessels and nerves at the position, so that the blood circulation is blocked, the nerve feel and the dominant function are abnormal, skin infection or necrosis and deep vein thrombosis of lower limbs are caused when the blood circulation is severe, even bad results such as osteofascial chamber syndrome and the like occur, if the affected limb swelling and pain is improperly treated, pain of a patient can be aggravated, complications are induced, and fracture healing is affected. If the fracture accumulates on the joints of the limbs, swelling usually lasts for a long time after the fracture, and especially for the fracture postoperative recovery period patients with healed cuts, local soft tissue swelling and pain can further aggravate joint movement disorder, influence the later rehabilitation training of the patients, cause joint movement disorder which is difficult to recover, and bring heavy psychological burden and huge economic burden to the patients and family members. The main treatment modes of the modern medicine aiming at postoperative swelling at present comprise lifting affected limbs, cold therapy, pressurizing and binding, applying an arterial and venous pump device, medical treatment, applying a negative pressure lymphatic drainage system and the like; the treatment method for postoperative pain mainly comprises oral administration, intravenous injection and intramuscular injection of analgesic drugs. However, these treatments are only suitable for short term applications and remain to be improved in terms of reducing swelling after fracture surgery with little effect on the concomitant limitation of joint movement.
Swelling after fracture belongs to the category of fracture complicated with 'muscle injury' in traditional Chinese medicine, and the traditional Chinese medicine considers that fracture and operation can cause local injury of tendons and veins at affected parts to cause blood overflow outside the veins, blood is blood stasis after leaving channels, and the swelling is caused by 'blood tangible' and 'death of illness swelling'. The adverse blood is water, stagnant blood stagnates in the limbs, qi movement is not smooth, water channels are not smooth, and body fluid is not distributed, so that water dampness is caused to stop locally to form swelling. When the limbs are damaged, qi and blood are damaged, nutrient and defensive qi are not completely used, viscera are not completely used, and when various external factors damage the organism, internal dysfunction of viscera can be caused, physiological activities of normal qi and blood circulation in the organism are blocked, so that venation is not smooth, qi stagnates and blood stasis are caused, and local pain is caused. Impaired tendons and vessels, localized stagnant blood, obstruction of qi and blood, and unfavorable qi movement, which leads to joint movement disorder. Accordingly, the present invention aims to provide a Chinese medicinal composition for treating local swelling and pain after fracture and joint movement limitation, so as to solve the above problems.
Disclosure of Invention
The application aims to provide a traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation, which has obvious effects of detumescence and analgesia and removing blood stasis and dredging collaterals for joint dysfunction, and is suitable for patients with swelling and joint movement limitation after fracture operation.
In order to achieve the above object, the technical scheme of the present invention is as follows: a traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation comprises the following components in parts by weight: 3-5 parts of raw radix aconiti, 3-5 parts of raw kusnezoff monkshood root, 3-5 parts of raw arisaema tuber, 5-10 parts of raw pollen typhae, 5-10 parts of frankincense, 5-10 parts of myrrh, 3-5 parts of safflower, 3-5 parts of red paeony root, 5-10 parts of raw rhubarb, 5-10 parts of beautiful sweetgum fruit, 5-10 parts of pubescent angelica root, 5-10 parts of drynaria rhizome, 1-3 parts of moxibustion licorice and 1-3 parts of honey.
Further, the paint comprises the following components in parts by weight: 3 parts of raw radix aconiti, 3 parts of raw radix aconiti kusnezoffii, 3 parts of raw arisaema tuber, 5 parts of raw pollen typhae, 5 parts of frankincense, 5 parts of myrrh, 3 parts of safflower, 3 parts of red paeony root, 5 parts of raw rhubarb, 5 parts of fructus liquidambaris, 5 parts of radix angelicae pubescentis, 5 parts of rhizoma drynariae, 1 part of moxibustion licorice and 1 part of honey.
Further, the paint comprises the following components in parts by weight: 4 parts of raw radix aconiti, 4 parts of raw radix aconiti kusnezoffii, 4 parts of raw arisaema tuber, 8 parts of raw pollen typhae, 7 parts of frankincense, 8 parts of myrrh, 4 parts of safflower, 4 parts of red paeony root, 7 parts of raw rhubarb, 8 parts of beautiful sweetgum fruit, 7 parts of pubescent angelica root, 8 parts of drynaria rhizome, 2 parts of moxibustion licorice and 2 parts of honey.
Further, the paint comprises the following components in parts by weight: 5 parts of raw radix aconiti, 5 parts of raw radix aconiti kusnezoffii, 5 parts of raw arisaema tuber, 10 parts of raw pollen typhae, 10 parts of frankincense, 10 parts of myrrh, 5 parts of safflower, 5 parts of red paeony root, 10 parts of raw rhubarb, 10 parts of beautiful sweetgum fruit, 10 parts of pubescent angelica root, 10 parts of drynaria rhizome, 3 parts of moxibustion licorice and 3 parts of honey.
Further, the preparation method of the traditional Chinese medicine composition for treating swelling after fracture operation and joint movement limitation comprises the following steps:
Step one, raw material pretreatment: weighing radix et rhizoma Rhei, pollen Typhae, olibanum, myrrha, carthami flos, radix Paeoniae Rubra, radix Aconiti Kusnezoffii, rhizoma arisaematis, fructus Lipuidambaris, radix Angelicae Pubescentis, rhizoma Drynariae, and radix Glycyrrhizae Preparata at a certain ratio, and grinding into superfine powder;
Step two: preparation of the composition external ointment: heating vaseline, stirring the above superfine powder, adding Mel, making into ointment, and naturally cooling at normal temperature to obtain the final product.
The action mechanism of the medicine of the invention: the monarch drug raw kusnezoff monkshood root and raw common monkshood mother root are firstly carried in Shennong's herbal channel, are pungent and bitter in taste, have strong toxicity and have the effects of dispelling wind and removing dampness, warming channels and relieving pain, and the effects of dispelling wind and resolving masses and reinforcing detumescence by adding the raw arisaema tuber; the compatibility of the raw pollen typhae, the frankincense, the myrrh, the safflower and the red paeony root has the efficacy of activating blood and dissolving stasis; for blood stasis, qi stagnation is not caused, qi circulation is caused, so that it is advisable to add drugs for expelling wind-damp and dredging channels and collaterals, such as Lipuidambaris, radix Angelicae Pubescentis and rhizoma Drynariae, on the basis of the original prescription; the 'long-term stasis can remove heat' is assisted with the cold-nature blood-activating stasis-removing medicine raw rhubarb so as to warm and disperse cold Wen Deyi and cause heat diarrhea without causing heat accumulation or even toxicity; finally, the honey is matched with the honey and the honey to blend the medicines and reduce toxicity.
After the scheme is adopted, the following beneficial effects are realized:
(1) In the application, the mutual requirements of the raw radix aconiti and the raw radix aconiti are adopted, and the modern pharmacological research shows that a plurality of aconitine alkaloids in the radix aconiti and the radix aconiti have obvious central analgesic effect, and can paralyze peripheral nerve endings when being externally used, and the effects of detumescence and analgesia of the raw arisaema are doubled.
(2) According to the application, the olibanum and the red paeony root are cooperated, so that the effect of treating limb swelling can be achieved; the olibanum has the effects of promoting blood circulation, promoting qi circulation, relieving pain, detumescence and promoting granulation, and can promote venous return and relieve limb swelling; the red paeony root has the effects of clearing heat, cooling blood, removing stasis and relieving pain, and can play the roles of activating blood and dissolving stasis; the olibanum and the red paeony root are cooperated to help relieve the symptoms of joint swelling.
(3) The drynaria rhizome is added in the application, and is used for fracture injury, bone and muscle pain and other symptoms, and has good effect on fracture postoperative recovery; and honey are added, so that the honey and the honey can play a role in reducing toxicity, the traditional Chinese medicines of all the components achieve a synergistic effect, and the local allergy caused by external medicines is reduced.
(4) The traditional Chinese medicine composition has obvious effects of detumescence, analgesia, stasis removal and vein relaxing for postoperative local swelling and joint dysfunction; the ointment-shaped external preparation can exert the drug effect to the maximum extent on the lesion part, and can effectively avoid toxic and side effects caused by toxic drugs.
Detailed Description
The following is a further detailed description of the embodiments:
Example 1
A traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation comprises the following components in parts by weight: 3-5 parts of raw radix aconiti, 3-5 parts of raw kusnezoff monkshood root, 3-5 parts of raw arisaema tuber, 5-10 parts of raw pollen typhae, 5-10 parts of frankincense, 5-10 parts of myrrh, 3-5 parts of safflower, 3-5 parts of red paeony root, 5-10 parts of raw rhubarb, 5-10 parts of beautiful sweetgum fruit, 5-10 parts of pubescent angelica root, 5-10 parts of drynaria rhizome, 1-3 parts of moxibustion licorice and 1-3 parts of honey.
Example two
The difference between this embodiment and the above embodiment is that: comprises the following components in parts by weight: 3 parts of raw radix aconiti, 3 parts of raw radix aconiti kusnezoffii, 3 parts of raw arisaema tuber, 5 parts of raw pollen typhae, 5 parts of frankincense, 5 parts of myrrh, 3 parts of safflower, 3 parts of red paeony root, 5 parts of raw rhubarb, 5 parts of fructus liquidambaris, 5 parts of radix angelicae pubescentis, 5 parts of rhizoma drynariae, 1 part of moxibustion licorice and 1 part of honey.
Example III
The difference between this embodiment and the above embodiment is that: comprises the following components in parts by weight: 4 parts of raw radix aconiti, 4 parts of raw radix aconiti kusnezoffii, 4 parts of raw arisaema tuber, 8 parts of raw pollen typhae, 7 parts of frankincense, 8 parts of myrrh, 4 parts of safflower, 4 parts of red paeony root, 7 parts of raw rhubarb, 8 parts of beautiful sweetgum fruit, 7 parts of pubescent angelica root, 8 parts of drynaria rhizome, 2 parts of moxibustion licorice and 2 parts of honey.
Example IV
The difference between this embodiment and the above embodiment is that: comprises the following components in parts by weight: 5 parts of raw radix aconiti, 5 parts of raw radix aconiti kusnezoffii, 5 parts of raw arisaema tuber, 10 parts of raw pollen typhae, 10 parts of frankincense, 10 parts of myrrh, 5 parts of safflower, 5 parts of red paeony root, 10 parts of raw rhubarb, 10 parts of beautiful sweetgum fruit, 10 parts of pubescent angelica root, 10 parts of drynaria rhizome, 3 parts of moxibustion licorice and 3 parts of honey.
Example five
The difference between this embodiment and the above embodiment is that:
the preparation method of the traditional Chinese medicine composition for treating swelling after fracture operation and joint movement limitation comprises the following steps:
Step one, raw material pretreatment: weighing radix et rhizoma Rhei, pollen Typhae, olibanum, myrrha, carthami flos, radix Paeoniae Rubra, radix Aconiti Kusnezoffii, rhizoma arisaematis, fructus Lipuidambaris, radix Angelicae Pubescentis, rhizoma Drynariae, and radix Glycyrrhizae Preparata at a certain ratio, and grinding into superfine powder;
step two: preparation of composition external paste solution: heating vaseline, stirring the above superfine powder, adding Mel, making into ointment, and naturally cooling at normal temperature to obtain the final product.
Experiment verification
120 Patients with healed incision after limb fracture operation but limited local swelling and joint movement are selected as study subjects, and the patients are divided into a first experimental group (30), a second experimental group (30), a third experimental group (30) and a control group (30) by adopting a random number table method; subjects were between 18 and 70 years of age.
Experiment group one: the raw materials comprise the following components in parts by weight: 3 parts of raw radix aconiti, 3 parts of raw radix aconiti kusnezoffii, 3 parts of raw arisaema tuber, 5 parts of raw pollen typhae, 5 parts of frankincense, 5 parts of myrrh, 3 parts of safflower, 3 parts of red paeony root, 5 parts of raw rhubarb, 5 parts of fructus liquidambaris, 5 parts of radix angelicae pubescentis, 5 parts of rhizoma drynariae, 1 part of moxibustion licorice and 1 part of honey; the preparation method of the formula is prepared by referring to the fifth example.
Experimental group two: comprises the following components in parts by weight: 4 parts of raw radix aconiti, 4 parts of raw radix aconiti kusnezoffii, 4 parts of raw arisaema tuber, 8 parts of raw pollen typhae, 7 parts of frankincense, 8 parts of myrrh, 4 parts of safflower, 4 parts of red paeony root, 7 parts of raw rhubarb, 8 parts of beautiful sweetgum fruit, 7 parts of pubescent angelica root, 8 parts of drynaria rhizome, 2 parts of moxibustion licorice and 2 parts of honey; the preparation method of the formula is prepared by referring to the fifth example.
Experimental group three: comprises the following components in parts by weight: 5 parts of raw radix aconiti, 5 parts of raw radix aconiti kusnezoffii, 5 parts of raw arisaema tuber, 10 parts of raw pollen typhae, 10 parts of frankincense, 10 parts of myrrh, 5 parts of safflower, 5 parts of red paeony root, 10 parts of raw rhubarb, 10 parts of beautiful sweetgum fruit, 10 parts of pubescent angelica root, 10 parts of drynaria rhizome, 3 parts of moxibustion licorice and 3 parts of honey; the preparation method of the formula is prepared by referring to the fifth example.
Control group: comprises the following components in parts by weight: adding edible pigment into vaseline to obtain topical ointment with similar color.
The post-treatment efficacy versus treatment for the 4 groups of patients is shown in table 1:
TABLE 1
Group of Number of examples Healing Has obvious effect Effective and effective Invalidation of
Experiment group one 30 15 10 5 0
Experiment group II 30 11 10 9 0
Experiment group III 30 8 12 10 0
Control group 30 3 5 12 10
As can be seen from table 1, compared with the control group, the first experimental group, the second experimental group and the third experimental group prepared by referring to the composition of the application have more sufficient effects on treating swelling and limited joint movement after fracture operation, and the preparation method can more sufficiently excite the drug property, so that the treatment effect is sufficient; the nutritional composition provided by the application can relieve swelling and limited joint movement after fracture operation to a certain extent, and improve symptoms and signs of the fracture.
The foregoing is merely an embodiment of the present application, and a specific structure and characteristics of common knowledge in the art, which are well known in the scheme, are not described herein, so that a person of ordinary skill in the art knows all the prior art in the application date or before the priority date, can know all the prior art in the field, and has the capability of applying the conventional experimental means before the date, and a person of ordinary skill in the art can complete and implement the present embodiment in combination with his own capability in the light of the present application, and some typical known structures or known methods should not be an obstacle for a person of ordinary skill in the art to implement the present application. It should be noted that modifications and improvements can be made by those skilled in the art without departing from the structure of the present application, and these should also be considered as the scope of the present application, which does not affect the effect of the implementation of the present application and the utility of the patent. The protection scope of the present application is subject to the content of the claims, and the description of the specific embodiments and the like in the specification can be used for explaining the content of the claims.

Claims (5)

1. A traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation is characterized in that: comprises the following components in parts by weight: 3-5 parts of raw radix aconiti, 3-5 parts of raw kusnezoff monkshood root, 3-5 parts of raw arisaema tuber, 5-10 parts of raw pollen typhae, 5-10 parts of frankincense, 5-10 parts of myrrh, 3-5 parts of safflower, 3-5 parts of red paeony root, 5-10 parts of raw rhubarb, 5-10 parts of beautiful sweetgum fruit, 5-10 parts of pubescent angelica root, 5-10 parts of drynaria rhizome, 1-3 parts of moxibustion licorice and 1-3 parts of honey.
2. The traditional Chinese medicine composition for treating swelling and limited joint movement after fracture surgery according to claim 1, wherein the traditional Chinese medicine composition is characterized in that: comprises the following components in parts by weight: 3 parts of raw radix aconiti, 3 parts of raw radix aconiti kusnezoffii, 3 parts of raw arisaema tuber, 5 parts of raw pollen typhae, 5 parts of frankincense, 5 parts of myrrh, 3 parts of safflower, 3 parts of red paeony root, 5 parts of raw rhubarb, 5 parts of fructus liquidambaris, 5 parts of radix angelicae pubescentis, 5 parts of rhizoma drynariae, 1 part of moxibustion licorice and 1 part of honey.
3. The traditional Chinese medicine composition for treating swelling and limited joint movement after fracture surgery according to claim 2, wherein the traditional Chinese medicine composition is characterized in that: comprises the following components in parts by weight: 4 parts of raw radix aconiti, 4 parts of raw radix aconiti kusnezoffii, 4 parts of raw arisaema tuber, 8 parts of raw pollen typhae, 7 parts of frankincense, 8 parts of myrrh, 4 parts of safflower, 4 parts of red paeony root, 7 parts of raw rhubarb, 8 parts of beautiful sweetgum fruit, 7 parts of pubescent angelica root, 8 parts of drynaria rhizome, 2 parts of moxibustion licorice and 2 parts of honey.
4. The traditional Chinese medicine composition for treating swelling after fracture surgery and joint movement limitation according to claim 3, wherein: comprises the following components in parts by weight: 5 parts of raw radix aconiti, 5 parts of raw radix aconiti kusnezoffii, 5 parts of raw arisaema tuber, 10 parts of raw pollen typhae, 10 parts of frankincense, 10 parts of myrrh, 5 parts of safflower, 5 parts of red paeony root, 10 parts of raw rhubarb, 10 parts of beautiful sweetgum fruit, 10 parts of pubescent angelica root, 10 parts of drynaria rhizome, 3 parts of moxibustion licorice and 3 parts of honey.
5. The traditional Chinese medicine composition for treating swelling and limited joint movement after fracture surgery according to claim 4, wherein the traditional Chinese medicine composition is characterized in that: the method for preparing the traditional Chinese medicine composition for treating swelling after fracture surgery and joint movement limitation according to any one of claims 1 to 4, comprising the following steps:
Step one, raw material pretreatment: weighing radix et rhizoma Rhei, pollen Typhae, olibanum, myrrha, carthami flos, radix Paeoniae Rubra, radix Aconiti Kusnezoffii, rhizoma arisaematis, fructus Lipuidambaris, radix Angelicae Pubescentis, rhizoma Drynariae, and radix Glycyrrhizae Preparata at a certain ratio, and grinding into superfine powder;
Step two: preparation of the composition external ointment: heating vaseline, stirring the above superfine powder, adding Mel, making into ointment, and naturally cooling at normal temperature to obtain the final product.
CN202410537998.2A 2024-04-30 2024-04-30 Traditional Chinese medicine composition for treating swelling and joint movement limitation after fracture operation Pending CN118403113A (en)

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