CN1183931C - Medicine for treating kidney disease - Google Patents

Abstract

The present invention relates to a medicine for treating nephrosis, which uses caulis lonicerae, milk vetch, fleece-flower root, Chinese yam rhizome, pseudostellaria root, liquorice, human placenta powder and rhubarb as raw materials to make watered pills. The medicine is suitable for treating chronic nephritis and nephrotic syndrome, and has especially good curative effect on the side effect caused by using hormone and relapse phenomena when hormone is reduced or stopped to be taken. The total effective rate reaches more than 95%, and the present invention provides the medicine for treating nephrosis, which has the advantages of reliable curative effect, no toxic or side effect and good clinic popularization value.

Description

A kind of medicine for the treatment of nephropathy

Technical field

The present invention relates to a kind of medicine for the treatment of nephropathy, more specifically saying so with the Chinese herbal medicine is the Chinese medicine preparation that raw material is made.

Background technology

At present, if the drug main of treatment chronic nephropathy is gone up gland 17-hydroxy-11-dehydrocorticosterone (abbreviation hormone) and some Chinese medicine preparation.Though they can make a part of patients clinical cure, the course of disease is longer, and hormone can have side effects, and the rebound phenomenon behind the inactive hormone is still the still unsolved difficult problem of current medical circle.

Summary of the invention

The purpose of this invention is to provide and a kind ofly can alleviate or eliminate the side effect that hormone causes and can solve a kind of effective Chinese medicine preparation that hormone is relied on.

Realize the main technical schemes of the object of the invention: based on understanding and the Therapeutic Principle of motherland's medical science to nephropathy mechanism, from motherland medicine treasure-house, filter out have nourishing kidney, spleen reinforcing, should the lung effect Caulis Lonicerae, the Radix Astragali, Radix Polygoni Multiflori, Rhizoma dioscoreae, Radix Pseudostellariae, Radix Glycyrrhizae, Placenta Hominis powder, Radix Et Rhizoma Rhei Chinese herbal medicine, make the watered pill according to a conventional method after crushed.

Medicine of the present invention is made (consumption is parts by weight) by following component:

Caulis Lonicerae 15-30 part, Radix Astragali 20-40 part, Radix Polygoni Multiflori 15-25 part,

Rhizoma dioscoreae 20-40 part, Radix Pseudostellariae 15-30 part, Radix Glycyrrhizae 5-15 part,

Placenta Hominis powder 5-10 part, Radix Et Rhizoma Rhei 5-15 part.

Medicine optimum formula of the present invention (parts by weight }:

25 parts of Caulis Loniceraes, 30 parts of the Radixs Astragali, 20 parts of Radix Polygoni Multiflori,

30 parts of Rhizoma dioscoreaes, 20 parts of Radix Pseudostellariaes, 10 parts in Radix Glycyrrhizae,

9 parts in Placenta Hominis powder, 9 parts of Radix Et Rhizoma Rhei.

Above-mentioned each component Chinese herbal medicine is made the watered pill according to a conventional method.

Medicine advantage of the present invention and effect:

The traditional Chinese medical science is thought: chronic nephropathy relates to spleen, lung, kidney three dirty losss, with the kidney loss the most very, and damp and hot through the course of disease all the time, because the life-time service hormone often brings deficiency of both YIN and YANG, accompanies damp and hot principal contradiction, and the present invention selects the Radix Astragali, Radix Pseudostellariae, Radix Polygoni Multiflori, Rhizoma dioscoreae, purple what car powder, gas, cloudy giving young employees remedial-courses in general knowledge and vocational skills for use, negative and positive two turn round and look at, and have diuretic concurrently, and it is dirty to take spleen, lung, kidney three into account; Caulis Lonicerae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei heat-clearing and toxic substances removing, the clear meridians apoplexy of energy, wet, pathogenic heat, Radix Et Rhizoma Rhei again can activating blood and promoting diuresis, therefore Chinese medicine preparation of the present invention has QI invigorating the moon and does not hinder wet, heat-clearing and toxic substances removing not hinder positive satisfactory to both parties effect, particularly use Caulis Lonicerae and Placenta Hominis powder two flavors in the Chinese medicine preparation, the former is meridians apoplexy, wet, pathogenic heat clearly, and latter's benefiting qi and nourishing blood, negative and positive tool are mended, the both has immunoregulation effect, and effect has positive effect at the antagonism hormone side effect with to hormone replacement.

Drug usage of the present invention: each 2 gram watered pills, every day three times, three months one courses of treatment.Pharmic function of the present invention with cure mainly: fill blood, regulate yin-yang, detoxifying, removing dampness, inducing diuresis to remove edema; Be applicable to treatment chronic nephritis, the nephrotic syndrome, especially to using the rebound phenomenon that occurs after side effect that hormone causes and hormone decrement or the drug withdrawal to have excellent curative.

Drug therapy hormonal dependent nephropathy 46 routine clinical observation result of the present invention:

1. clinical data: male 19 examples, women 27 examples in 46 examples, in age 14-46 year, average 28 years old: the course of disease was the shortest 9 months, and is the longest 2 years.

The hormone therapy history is all arranged before the prescription on individual diagnosis, and drug withdrawal or reduce to the minimum dose seasonal disease repeatedly.In 46 examples, oliguria 24 examples, edema 41 examples, ascites 6 examples, hypertension 43 examples, hematuria 40 examples, albuminuria 26 examples, hypercholesterolemia 22 examples.

2. Therapeutic Method: take the watered pill 3 grams that the present invention makes, day clothes 3 times serve on 1-3 the course of treatment 3 months courses of treatment at every turn, and the obvious person of ascites or edema suitably strengthens the Radix Et Rhizoma Rhei consumption, during the treatment decrescence hormone dosage up to drug withdrawal.

3. therapeutic effect

(1) criterion of therapeutical effect

A. recovery from illness: symptom and sign disappears, and lab testing is normal, does not recur behind the hormone of stopping using;

B. produce effects: symptom and sign disappears substantially, and lab testing significantly improves, and recurrence is than the lighter after the drug withdrawal;

C. invalid: treating did not have the improver with clinical symptoms and laboratory examination in three months.

(2) result: 30 examples of fully recovering (accounting for 65.2%), produce effects 14 examples (accounting for 30.4%), invalid 2 examples (accounting for 4.4%), total effective rate 95.9%.

4. model case

Lee *, the woman, 21 years old, the peasant, edema 2 years, oliguria, weak 2 months, be admitted to hospital on November 14th, 1993, come before the institute successively at certain county hospital with nephrotic syndrome hospitalization, curative effect is not good enough, question closely medical history, the each state of an illness of patient is all relevant with the oral decrement of prednisone repeatedly, and when reducing to every day during a slice left and right sides, the state of an illness often increases the weight of suddenly.

Have a medical check-up: puffiness of face, the eyes blepharoptosis, palpebral fissure narrows down, two lower limb are pitting edema, cardiopulmonary (-), urine protein (+++), erythrocyte (+++), granular cast a little, plasma cholesterol 10.3mmol/L.

Diagnosis: the nephrotic syndrome, through the doctor trained in Western medicine diuresis, increase hormone dosage after, transference cure, only the urine chemical examination takes a turn for the better not remarkable, use medicine of the present invention, each 2 grams, every day three times, and hormone dosage decrescence, withdraw from after January, further consultation after three months, all diseases all disappear, and the urine chemical examination is normal, advised continuous clothes three months, and followed up a case by regular visits to and do not have recurrence in 2 years.

The specific embodiment

Further specify characteristics of the present invention below by specific embodiment.

Embodiment 1

Take by weighing raw material by following proportioning:

2.5 kilograms of Caulis Loniceraes, 3 kilograms of the Radixs Astragali, 2 kilograms of Radix Polygoni Multiflori, 3 kilograms of Rhizoma dioscoreaes, 2 kilograms of Radix Pseudostellariaes, 1 kilogram in Radix Glycyrrhizae, 0.9 kilogram in Placenta Hominis powder, each 0.9 kilogram of Radix Et Rhizoma Rhei.

To make the watered pill by known method after the above-mentioned raw materials drying and crushing.

Claims (3)

1. medicine for the treatment of nephropathy is characterized in that it being the medicament that the raw material of following parts by weight is made:

Caulis Lonicerae 15-30 part, Radix Astragali 20-40 part, Radix Polygoni Multiflori 15-15 part,

Rhizoma dioscoreae 20-40 part, Radix Pseudostellariae 15-30 part, Radix Glycyrrhizae 5-15 part,

Placenta Hominis powder 5-10 part, Radix Et Rhizoma Rhei 5-15 part.

2. by the described medicine of claim 1, it is characterized in that it being the medicament that the raw material of following parts by weight is made:

25 parts of Caulis Loniceraes, 30 parts of the Radixs Astragali, 20 parts of Radix Polygoni Multiflori,

30 parts of Rhizoma dioscoreaes, 20 parts of Radix Pseudostellariaes, 10 parts in Radix Glycyrrhizae,

9 parts in Placenta Hominis powder, 9 parts of Radix Et Rhizoma Rhei.

3. according to the medicine of claim 1 or 2 described treatment nephropathy, wherein said preparation is the watered pill.