CN118307422A - 用于递送活性剂的可生物降解脂质 - Google Patents

用于递送活性剂的可生物降解脂质 Download PDF

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Publication number
CN118307422A
CN118307422A CN202410415224.2A CN202410415224A CN118307422A CN 118307422 A CN118307422 A CN 118307422A CN 202410415224 A CN202410415224 A CN 202410415224A CN 118307422 A CN118307422 A CN 118307422A
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lipid
group
alkyl
cationic
alkenyl
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CN202410415224.2A
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Chinese (zh)
Inventor
穆图萨米·贾亚拉曼
何果
马丁·迈尔
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Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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Publication of CN118307422A publication Critical patent/CN118307422A/zh
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    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
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    • C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
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CN202410415224.2A 2018-10-01 2019-09-27 用于递送活性剂的可生物降解脂质 Pending CN118307422A (zh)

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US201862739548P 2018-10-01 2018-10-01
US62/739,548 2018-10-01
CN201980077559.5A CN113164379B (zh) 2018-10-01 2019-09-27 用于递送活性剂的可生物降解脂质
PCT/US2019/053617 WO2020072324A1 (en) 2018-10-01 2019-09-27 Biodegradable lipids for the delivery of active agents

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