CN1181247A - External-use Chinese medicine preparation for treating skin ulcer - Google Patents
External-use Chinese medicine preparation for treating skin ulcer Download PDFInfo
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- CN1181247A CN1181247A CN 96116025 CN96116025A CN1181247A CN 1181247 A CN1181247 A CN 1181247A CN 96116025 CN96116025 CN 96116025 CN 96116025 A CN96116025 A CN 96116025A CN 1181247 A CN1181247 A CN 1181247A
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Abstract
An exterior-used Chinese medicine in the form of liquid or ointment for treating burn, scald, stomatitis, acute or chronic skin ulcer, eczema, foot ringworm infection and pile is prepared through decocting liquorice root, flavescent sophora root, arnebia root ad musk in sesame oil, and features high curative effect (92.^% curative rate and 100% effective rate), no recurrence and no any toxic by-effect.
Description
The present invention relates to a kind of Chinese medicine preparation for the treatment of skin ulcer.
All kinds of acute and chronic skin ulcers occupy bigger ratio in department of dermatologry is clinical, most cases are caused by irritated and other wound, as burn, oral ulcer, acute and chronic skin ulcer, various eczema, tinea pedis infection, external genital ulcer or the like.Burn has the medicine of multiple external to treat, and comprises Chinese prescription.Prescription has nothing in common with each other, and curative effect has nothing in common with each other, and these medicines then do not have significant curative effect to other skin ulcer.Other skin ulcer does not also have with the medicine for external use therapeutic effect can be gratifying.
The purpose of this invention is to provide a kind of Chinese medicine for outer use with treatment skin ulcer that component is few, curative effect is high, therapeutic domain is wide.
The Chinese medicine for outer use of this treatment skin ulcer, the major technique characteristics are to contain following Chinese medicine ingredients: in the raw material parts by weight, 80～100 parts in Radix Glycyrrhizae, 20～30 parts of Radix Sophorae Flavescentiss, 20～30 parts of Radix Arnebiae (Radix Lithospermi)s.
In above-mentioned Chinese medicine ingredients, also can add 0.5～1 part in Moschus.
The selected optimum weight umber of the above Chinese medicine ingredients is: 100 parts in Radix Glycyrrhizae, 30 parts of Radix Sophorae Flavescentiss, 30 parts of Radix Arnebiae (Radix Lithospermi)s, 1 part in Moschus.
The best preparation that the Chinese medicinal ingredients of the above makes is to boil medicinal liquid or the ointment that forms with Oleum sesami, needs Radix Glycyrrhizae 80～100g, Radix Sophorae Flavescentis 20～30g, Radix Arnebiae (Radix Lithospermi) 20～30g, Moschus 0.5～1g in every 500ml Oleum sesami.Optimum weight is Herba vallisneriae Spiralis 100g, Radix Sophorae Flavescentis 30g, Radix Arnebiae (Radix Lithospermi) 30g, Moschus 1g.
Radix Glycyrrhizae is a principal agent, drug study proves, Radix Glycyrrhizae contains Monosodium glycyrrhetin, ammonium glycyrrhizinate, can influence oozing out the phase of subcutaneous granulation capsule inflammation effectively, the intensity of its effect has the effect and the antitoxin antiinflammatory antiallergic action of similar adrenocortical hormone, clinically Radix Glycyrrhizae be mainly used in eliminate the phlegm, disease and all medicine blending effects such as antitussive, spasmolytic, and be mostly for oral administration, seldom use as external and principal agent.Radix Sophorae Flavescentis contains matrine, and the various skin fungus is had good inhibition effect, finds to have again the merit of putrefaction removing and tissue regeneration promoting in this treatment.Radix Arnebiae (Radix Lithospermi) have invigorate blood circulation, the effect of removing heat from blood, detoxifcation.Moschus has the refreshment of having one's ideas straightened out, the meridian dredging, promoting blood circulation and detumescence, impels the effect of ulceration healing.Each medicine is coordinated mutually, has Oleum sesami to infiltrate again and wherein moistens foster skin, convergence wound surface.With heat-clearing and toxic substances removing.The dampness convergence is also executed, and directly acts on ulceration, sterilizing, and it is quick to produce effects.
Manufacture method is: with Oleum sesami the raw material Radix Glycyrrhizae is put into earlier and soaked 24 hours, decoct to Radix Glycyrrhizae with slow fire and to become coke yellow, with putting into Radix Sophorae Flavescentis after the filtered through gauze slagging-off, heated and boiled took advantage of in one minute deep fat add Radix Arnebiae (Radix Lithospermi) boil once more after filter cleaner at once, add an amount of Cera Flava, put into the Moschus packing box that stirs to 50～60 ℃ (or its following times) Deng oil is cool, a little grinds molten reuse afterwards to Moschus with 75% ethanol earlier, is beneficial to and the medicinal liquid mix homogeneously.
Radix Glycyrrhizae was soaked back active ingredient major part and disengages through 24 hours, active ingredient disengages fully after sallow through decocting, and Radix Sophorae Flavescentis is heat-resisting, fries in shallow oil for a long time but the not anti-hyperpyrexia of the active ingredient of Radix Arnebiae (Radix Lithospermi) is difficult.
On the make add Cera Flava, obtain ointment (unguentum), do not add Cera Flava and obtain medicinal liquid (oil preparation).
The present invention cures mainly scald, burn, oral ulcer, acute and chronic skin ulcer (comprising external genital ulcer), various eczema, tinea pedis infection, also can be used for changing dressings behind hemorrhoid and the hemorrhoid operation.Therapeutic domain is wider.Good effect, nothing recurrence, no any poison are paid effect, and component is few, moderate.If ulcer later stage or lighter eczema etc. can make the treatment price lower without Moschus during Chinese medicine is formed like this, the hemorrhoid patients for anemia of pregnant woman and women breast-feeding their children is a kind of good effect, a medicine that does not have the effect of paying especially.Through nearly 2 years the most typical patient's 81 examples of treatment, cure rate 92.6%, effective percentage 100%, with SANHUANG pearl cream, the contrast of moist expose burn ointment observation of curative effect, effect of the present invention is fast, and good effect is listed as follows:
| Grouping | The example number | Recovery from illness % | Produce effects % | Improvement % | Invalid % | Total effective rate % |
| Treatment | ????81 | ??92.6 | ????7.4 | ????0 | ????0 | ??100 |
| Contrast | ????36 | ??58.33 | ????22.2 | ????11.1 | ????8.23 | ??91.62 |
The treatment group is the present invention, and matched group is a moist expose burn ointment, is produced by Changqing, Shandong pharmaceutical factory, cures mainly various burn and scald, chemical burn, wound infections, traumatic infection and all ulcer in body surfaces, hypertrophy cicatrix, hemorrhoid etc.
Treatment group and matched group have significant difference, and the visible detumescence in the 2nd day after medication of treatment group, alleviation of pain, skin ulcer face dope reduce by the incrustation of can drying up in 2～3 days, decrustation in general 4～7 days, detumescence in the 4th day after the matched group medication, alleviation of pain, skin ulcer face pus reduced in 6～7 days, withered incrustation, decrustation in about 10 days.
Using method of the present invention, earlier with ulcer surface with 0.1% ethacridine solution soak reuse 75% alcohol disinfecting wound surface after about 1 hour, then medicinal liquid of the present invention or ointment are applied to ulcer surface, ulcer surface is oozed out the repeatedly medication of heavier position,, wound color fresh place shallow to ulcer surface can select for use medicinal liquid of the present invention to smear or medicinal liquid, ointment are used alternatingly, help ulceration particularly mucosa heal outward, the number of times of changing dressings is decided by ulceration pus secretions, pus once a day for a long time, ooze out after a little while can 2～3 days once.
Model case:
Example 1: * * *, the man, 50 years old is that Zhong Zhen Xin Lu people from village respected in the Linzi District, Zibo City.Drive the motor tricycle overturning in June, 1996 and injure left lower extremity by a crashing object, scalded bilateral buttocks, two lower limb epimeres and perineal position by boiled water in the water tank.Tear left ankle joint dislocation, skin scalds such as perineal position open with the open bone of left tibia and fibula.Live surgical intervention, basicly stable through treatment wound situation, but skin ulcer do not have after with moist expose burn ointment and alleviates and increase the weight of gradually, and patient's sufferings are accompanied each other, and misery is very much.Patient's listlessness, 39 ℃ of body temperature, routine blood test shows leukocyte 15.7 * 109/l, neutrophilic granulocyte 0.94.The department of dermatologry situation: the bilateral buttocks, two lower limb and perineal position diffusivity redness, erosion is overflowed more very, and wound surface is deep mixed, and the surface has a large amount of yellow mucus to cover, and very heavy stink is arranged, and patient limits because of ulcer surface, can only pitch lower limb and lie on the back.Examine the back and use ointment of the present invention behind the routine disinfection, days 2 times, ooze out very heavy position and repeatedly smear at any time, sufferings obviously alleviate after one day, the sleep that patient's readme evening is beautiful one big, body temperature is 37.5 ℃ after 3 days.Shallow wounds is near healing, and having the green meat blastogenesis long, the scrotum glans part oozes out and stops, no stink, diet increases, the more preceding improvement of the 1 week most of ulcer surface in back, the ulcer area obviously dwindles, wound healing after January, only leave two lower limb epimere skin pigments and take off mistake, patient recovers orthobiosis, after February, follows up a case by regular visits to and does not have recurrence.
Example two: * * *, the man, 45 years old is Zhu Tai town, Linzi District, Zibo City Xin Li people from village.Before 6 years during work ankle accidentally collision on a reinforcing bar top, about about 2cm, with at this village's clinic bandaging method for treating.But wound suppurates always in 5 years thereafter, oozes out, and advances over one year that wound enlarges gradually, and pain especially is work unbearably night, and limitation of activity loses work capacity at last, in my section's diagnosis and treatment of in June, 1996.Department of dermatologry situation: the terminal large stretch of rotten to the corn face of left lower extremity, reach about 3cm, ooze out severity, tie yellow crusts on every side, niff is arranged, the anklebone that mays be seen indistinctly behind the debridement, disinfection appears, with the conscious pain relief of patient after behind the ointment of the present invention 1 day, can sleep night, and patient wound pus reduces after 2 days, and ulcer surface obviously dwindles after 5 days, green meat hamartoplasia is arranged, patient can leave the bed free movable, continues medication in per 3 days once, and a month back check wound is closely fully recovered, wound surface is long flat, the calm speckle of brown is seen in the check part after February, and patient can do light farm work by descending, and recurrence is not seen in check after half a year.
Embodiment one:
By manufacture method of the present invention, Oleum sesami 500ml, Radix Glycyrrhizae 100g, Radix Sophorae Flavescentis 25g, Radix Arnebiae (Radix Lithospermi) 20g, Moschus 0.5g, Cera Flava be an amount of, obtain unguentum (ointment), do not add Cera Flava and obtain medicinal liquid.
Embodiment two:
By manufacture method of the present invention, Oleum sesami 500ml, Radix Glycyrrhizae 100g, Radix Sophorae Flavescentis 30g, Radix Arnebiae (Radix Lithospermi) 30g, Moschus 1g, Cera Flava be an amount of, obtain unguentum (ointment), do not add Cera Flava and obtain medicinal liquid.
Embodiment three:
By manufacture method of the present invention, Oleum sesami 500ml, Radix Glycyrrhizae 80g, Radix Sophorae Flavescentis 20g, Radix Arnebiae (Radix Lithospermi) 20g, Cera Flava be an amount of, obtain unguentum (ointment).
Embodiment four:
By manufacture method of the present invention, Oleum sesami 500ml, Radix Glycyrrhizae 90g, Radix Sophorae Flavescentis 30g, Radix Arnebiae (Radix Lithospermi) 28g, obtain medicinal liquid.
Claims (10)
1, a kind of Chinese medicine for outer use for the treatment of skin ulcer is characterized in that containing following Chinese medicine ingredients, in the raw material parts by weight: 80～100 parts in Radix Glycyrrhizae, 20～30 parts of Radix Sophorae Flavescentiss, 20～30 parts of Radix Arnebiae (Radix Lithospermi)s.
2, Chinese medicine for outer use according to claim 1 is characterised in that and also contains 0.5～1 part in Moschus.
3, Chinese medicine for outer use according to claim 1 is characterised in that it is to boil medicinal liquid or the ointment that forms by described Chinese medicinal ingredients and Oleum sesami, needs Radix Glycyrrhizae 80～100g, Radix Sophorae Flavescentis 20～30g, Radix Arnebiae (Radix Lithospermi) 20～30g in every 500ml Oleum sesami.
4, Chinese medicine for outer use according to claim 3 is characterised in that also to comprise Moschus 0.5～1g.
5,, be characterised in that the selected optimum weight umber of each Chinese medicine ingredients is: 100 parts in Radix Glycyrrhizae, 30 parts of Radix Sophorae Flavescentiss, 30 parts of Radix Arnebiae (Radix Lithospermi)s, 1 part in Moschus according to claim 1,2,3,4 described Chinese medicine for outer use.
6, a kind of method for preparing the described Chinese medicine for outer use of claim 1, be characterised in that: Radix Glycyrrhizae is put into Oleum sesami and soaked 24 hours, decoct to Radix Glycyrrhizae with slow fire and to become coke yellow, put into Radix Sophorae Flavescentis behind the filter cleaner, boiled 1 minute, take advantage of deep fat to add Radix Arnebiae (Radix Lithospermi), filter cleaner at once after boiling obtains medicinal liquid.
7, method according to claim 6, being characterised in that needs Radix Glycyrrhizae 80～100g, Radix Sophorae Flavescentis 20～30g, Radix Arnebiae (Radix Lithospermi) 20～30g in every 500ml Oleum sesami.
8, method according to claim 6 is characterised in that adding an amount of Cera Flava behind the last filter cleaner obtains ointment.
9, according to claim 6,7,8 described methods, be characterised in that putting into Moschus in the medicinal liquid that obtains or ointment temperature during at 50～60 ℃ stirs, the parts by weight of Moschus are 0.5～1.
10, method according to claim 7 is characterised in that earlier a little grinds molten reuse afterwards to Moschus with 75% ethanol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96116025A CN1061865C (en) | 1996-10-29 | 1996-10-29 | External-use Chinese medicine preparation for treating skin ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96116025A CN1061865C (en) | 1996-10-29 | 1996-10-29 | External-use Chinese medicine preparation for treating skin ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1181247A true CN1181247A (en) | 1998-05-13 |
| CN1061865C CN1061865C (en) | 2001-02-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96116025A Expired - Fee Related CN1061865C (en) | 1996-10-29 | 1996-10-29 | External-use Chinese medicine preparation for treating skin ulcer |
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| Country | Link |
|---|---|
| CN (1) | CN1061865C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103054969A (en) * | 2013-02-06 | 2013-04-24 | 山东省立医院 | Compound skin disinfectant and preparation method thereof |
| CN109453111A (en) * | 2018-12-27 | 2019-03-12 | 李萍 | A kind of canker sore ointment |
| CN112641831A (en) * | 2020-12-28 | 2021-04-13 | 江苏耐雀生物工程技术有限公司 | Repairing gel for treating infantile eczema and preparation method thereof |
| CN116889585A (en) * | 2023-08-30 | 2023-10-17 | 高敏 | Radix lithospermi sore healing oil, preparation method and application thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078645A (en) * | 1993-04-20 | 1993-11-24 | 谢民福 | Antiphlogistic oil for external use and compound method thereof |
| CN1053820C (en) * | 1994-10-18 | 2000-06-28 | 叶太华 | Medicine for treatment of burn and scald and its preparation |
-
1996
- 1996-10-29 CN CN96116025A patent/CN1061865C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103054969A (en) * | 2013-02-06 | 2013-04-24 | 山东省立医院 | Compound skin disinfectant and preparation method thereof |
| CN103054969B (en) * | 2013-02-06 | 2014-08-13 | 山东省立医院 | Compound skin disinfectant and preparation method thereof |
| CN109453111A (en) * | 2018-12-27 | 2019-03-12 | 李萍 | A kind of canker sore ointment |
| CN112641831A (en) * | 2020-12-28 | 2021-04-13 | 江苏耐雀生物工程技术有限公司 | Repairing gel for treating infantile eczema and preparation method thereof |
| CN112641831B (en) * | 2020-12-28 | 2022-09-27 | 江苏耐雀生物工程技术有限公司 | Repairing gel for treating infantile eczema and preparation method thereof |
| CN116889585A (en) * | 2023-08-30 | 2023-10-17 | 高敏 | Radix lithospermi sore healing oil, preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1061865C (en) | 2001-02-14 |
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