CN1180545A - Compound bitter gourd preparation - Google Patents
Compound bitter gourd preparation Download PDFInfo
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- CN1180545A CN1180545A CN 96120242 CN96120242A CN1180545A CN 1180545 A CN1180545 A CN 1180545A CN 96120242 CN96120242 CN 96120242 CN 96120242 A CN96120242 A CN 96120242A CN 1180545 A CN1180545 A CN 1180545A
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- pharmaceutical composition
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- fructus momordicae
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Abstract
A compound medicine for curing diabetes with 92.5% of effective rate is prepared from balsom pear as main raw material, bootle gourd and common guava bark.
Description
The present invention relates to a kind of crude vegetable Fructus Momordicae charantiae with integration of edible and medicinal herbs, inferior waist calabash is the Chinese medicine preparation that primary raw material is made, said preparation can be used for treating diabetes, belongs to field of traditional Chinese.
One of at present the most common clinically and disease that sickness rate is the highest is a non-insulin-dependent diabetes mellitus, shows that according to interrelated data there are about 1.2 hundred million people of diabetics in the whole world, in China 21,000,000 people is arranged approximately.According to another the computerized information news messages of nineteen ninety-five, in 10 kinds of the highest diseases of Asia mortality rate, the sickness rate of diabetes has reached so serious level, so that the threat that will bring above the infectious disease that comprises acquired immune deficiency syndrome (AIDS).Relevant expert's prediction, in from now on 15 years, the popularity degree of area, Asia diabetes will be present 3 times, will influence 1.4 hundred million population by 2010.Quick senescence in China along with population is suffered from the number of diabetes and will be brought up to 14% rapidly from accounting for 2% of population, and these cases will cause the complication of vascular nervous system, so that blind, renal failure and acra two serious consequence of waiting indefinitely occurs.The main cause that the onset diabetes rate increases year by year is that in the country that these economy develop rapidly, people have abandoned traditional pattern of life, turn to the unsound Western lifestyle of taking in Hi CHO, high heat.Many Asian countries have difficulty in taking a step aspect the basic health medical treatment providing, and the cost of treatment diabetes comprises that expenses such as rehabilitation and kidney dialysis more make these countries make the matter worse.
The main method of treatment diabetes has three kinds at present, first oral therapeutic drug, and as sulphanylureas glyburide and even second filial generation medicine gliquidone etc., main effect is to stimulate the beta Cell of islet excreting insulin.Thereby blood sugar lowering concentration, the islet cells of suffering from diabetes then has been among the morbid state, and secreted insulin is in relative deficiency or exists " quality " problem.If the mode that adopt to stimulate produces insulin, beta Cell of islet can only be in the chronic fatigue state so, like this will vicious cycle, it is a kind of short-term effect, be unfavorable for islet cells recuperation and rehabilitation in the morbid state, and this class drug use is improper also hypoglycemia can to take place.Oral medicine commonly used at present also has biguanides, and this class drug side effect is big, and the possibility that lactic acidosis takes place is arranged, and takes for a long time and can cause hepatorenal damage, has not advocated use now.It two is insulin substitution therapies, though curative effect certainly, because injection inconvenience, the medicine high price is expensive, and except that type i diabetes was forced in order to earn a bare living use, most of type ii diabetes was difficult to accept or adhere to for a long time.Therefore people thirst for having a kind ofly can orally have the Chinese patent medicine of ILA to appear on the market again.It three is tcm therapies, and medicine typing is adopted in Chinese traditional treatment mostly.With the principle of disease plus-minus,,, also there is not a kind of ideal Chinese patent medicine to be approved by medical circle and vast diabetics except adopting Chinese medicine and western medicine in conjunction with the diabetes pill that adds with western medicine composition glyburide although many kinds of Chinese patent medicines are also arranged in the market.
The objective of the invention is according to theory of Chinese medical science,, develop a kind of effective treatment diabetes and the pharmaceutical preparation of nontoxic pair of effect in conjunction with modern science and technology and process.
Pharmaceutical composition of the present invention composed as follows:
Fructus Momordicae charantiae 70-85 weight portion
Inferior waist calabash 10-30 weight portion
Cortex psidii guajavae 5-20 weight portion
The preferred weight proportioning of aforementioned pharmaceutical compositions is as follows:
Fructus Momordicae charantiae 75-85
Inferior waist calabash 15-20
Cortex psidii guajavae 5-10
Pharmaceutical composition of the present invention can be prepared into various pharmaceutical dosage forms according to the preparation process of routine, for example tablet, pill, capsule, oral liquid, powder etc.
The preparation method of medicine capsule of the present invention:
Get bright Fructus Momordicae charantiae, inferior waist calabash by said ratio, clean, remove seed, squeeze the juice, gained juice is centrifugal, discard precipitation, get supernatant, technology lyophilization routinely obtains lyophilized powder.
Get Cortex psidii guajavae again, clean, oven dry is pulverized, and the water extracting method adds decocting in water and carries routinely, leach cooking liquid is filtered, and the concentrated extractum that obtains, after drying, the pulverizing, mix with above-mentioned lyophilized powder, pulverize once more, cross 100 mesh sieves, encapsulated, every contains quite living medication amount is the 0.25-0.5 gram.
The preparation method of medicinal tablet of the present invention:
Get bright Fructus Momordicae charantiae, inferior waist calabash by described proportioning, clean, remove seed, squeeze the juice, gained juice is centrifugal, discard precipitation, get supernatant, technology lyophilization routinely obtains lyophilized powder.
Get Cortex psidii guajavae again, clean, oven dry, pulverize, the water extracting method adds decocting in water and carries routinely, and leach cooking liquid is filtered, and the concentrated extractum that obtains, after drying, the pulverizing, with above-mentioned lyophilized powder mix homogeneously, in 1: the ratio of 1-3 adds starch, guiding humid medium, pelletize, granulate is gone into tablet machine, tabletting, make tablet, it is the 0.25-0.5 gram that every content of dispersion quite contains the crude drug amount.
Compared with the prior art medicine of the present invention has outstanding advantage, and compatibility of drugs of the present invention is reasonable, wherein contains the biological activity bitter gourd polypeptide, utilize the pharmacological property of vegetable active protein to have complementary advantages, complement each other, improved the unit active ingredient, and improved clinical efficacy than single preparations of ephedrine.Medicine of the present invention can obviously reduce the blood sugar level of glucose tolerance test owing to the reasonable compatibility of prescription, and the treatment non-insulin-dependent diabetes mellitus is had significant curative effect, simultaneously insulin dependent diabetes mellitus (IDDM) is also had tangible blood sugar lowering effect.Through clinical observation, effective percentage reaches more than 92.5%, and hypoglycemic effect is very remarkable.
Embodiment 1
Get 80 kilograms in Fructus Momordicae charantiae, 15 kilograms in inferior waist calabash is cleaned, and removes seed, squeezes the juice, and centrifugalize discards precipitation, gets supernatant, and lyophilization gets 10 kilograms of lyophilized powders, and is standby.Get 6 kilograms of Cortex psidii guajavaes again, clean, oven dry is pulverized, add 3 times of amounts of water, decocted 1.5 hours, medical filtration is standby, medicinal residues add 2 times of amounts of water again, decoct medical filtration 1 hour, merge medicinal liquid twice, be condensed into extractum, drying, pulverize, mix, pulverize again with above-mentioned lyophilized powder, cross 100 mesh sieves, encapsulated, every 0.25 gram.
The instructions of taking of medicine capsule of the present invention is oral every day three times, each 2-3 grain.
Claims (5)
1, a kind of compound balsom pear pharmaceutical composition is characterized in that: it is made up of the component of following weight parts:
Fructus Momordicae charantiae 70-85
Inferior waist calabash 10-30
Cortex psidii guajavae 5-20.
2, Fructus Momordicae charantiae pharmaceutical composition as claimed in claim 1 is characterized in that it is made up of the component of following weight parts:
Fructus Momordicae charantiae 75-85
Inferior waist calabash 15-20
Cortex psidii guajavae 5-10.
3, as the pharmaceutical composition of claim 1 or 2, it is characterized in that: it is any pharmaceutical dosage form that is suitable for clinically.
4, pharmaceutical composition as claimed in claim 3 is characterized in that it is a capsule.
5, pharmaceutical composition as claimed in claim 4 is characterized in that it is a tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96120242 CN1180545A (en) | 1996-10-24 | 1996-10-24 | Compound bitter gourd preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96120242 CN1180545A (en) | 1996-10-24 | 1996-10-24 | Compound bitter gourd preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1180545A true CN1180545A (en) | 1998-05-06 |
Family
ID=5126212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96120242 Pending CN1180545A (en) | 1996-10-24 | 1996-10-24 | Compound bitter gourd preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1180545A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011123995A1 (en) * | 2010-04-09 | 2011-10-13 | 铜陵市维新投资咨询有限公司 | Traditional chinese medicine composition for treating diabetes and preparation method thereof |
| CN102552469A (en) * | 2011-12-28 | 2012-07-11 | 林健 | Health-care product with assistant treatment effect on diabetes, hyperlipidemia and hypertension |
| US9034400B2 (en) | 2011-01-28 | 2015-05-19 | Piramal Enterprises Limited | Process for preparation of a herbal extract |
-
1996
- 1996-10-24 CN CN 96120242 patent/CN1180545A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011123995A1 (en) * | 2010-04-09 | 2011-10-13 | 铜陵市维新投资咨询有限公司 | Traditional chinese medicine composition for treating diabetes and preparation method thereof |
| US9034400B2 (en) | 2011-01-28 | 2015-05-19 | Piramal Enterprises Limited | Process for preparation of a herbal extract |
| CN102552469A (en) * | 2011-12-28 | 2012-07-11 | 林健 | Health-care product with assistant treatment effect on diabetes, hyperlipidemia and hypertension |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |