CN118019521A - 雷拉地尔的制剂 - Google Patents
雷拉地尔的制剂 Download PDFInfo
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- CN118019521A CN118019521A CN202280060141.5A CN202280060141A CN118019521A CN 118019521 A CN118019521 A CN 118019521A CN 202280060141 A CN202280060141 A CN 202280060141A CN 118019521 A CN118019521 A CN 118019521A
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
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- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
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- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US202163230331P | 2021-08-06 | 2021-08-06 | |
| US63/230,331 | 2021-08-06 | ||
| PCT/US2022/039543 WO2023014956A1 (en) | 2021-08-06 | 2022-08-05 | Formulations of radiprodil |
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| CN118019521A true CN118019521A (zh) | 2024-05-10 |
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| CN202280060141.5A Pending CN118019521A (zh) | 2021-08-06 | 2022-08-05 | 雷拉地尔的制剂 |
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| EP (1) | EP4380547A1 (https=) |
| JP (1) | JP2024529185A (https=) |
| KR (1) | KR20240052765A (https=) |
| CN (1) | CN118019521A (https=) |
| AU (1) | AU2022323381A1 (https=) |
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| CO (1) | CO2024002715A2 (https=) |
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| MX (1) | MX2024001744A (https=) |
| PE (1) | PE20241385A1 (https=) |
| WO (1) | WO2023014956A1 (https=) |
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| WO2025137652A2 (en) * | 2023-12-20 | 2025-06-26 | Grin Therapeutics, Inc. | Methods of using radiprodil in the treatment of disorders |
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| CA2453383C (en) | 2001-07-24 | 2010-04-06 | Richter Gedeon Vegyeszeti Gyar Rt | Piperidine derivatives as nmda receptor antagonists |
| CA2730253A1 (en) * | 2008-07-08 | 2010-01-14 | Alphonso Higuera | Novel crystalline form of 2-[4-(4-fluoro-benzyl)-piperidine-1-yl]-2-oxo-n-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide |
| AU2009282822A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating CNS disorders |
| HUP0900130A3 (en) * | 2009-03-03 | 2012-02-28 | Richter Gedeon Nyrt | Novel crystalline hydrate, amorphous and polymorphic forms of dihydro-benzoxazole-6-yl-acetamide derivative and processes for their preparation |
| US8328687B2 (en) | 2010-07-09 | 2012-12-11 | Ford Global Technologies, Llc | Method for controlling an engine that may be automatically stopped |
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- 2022-08-05 IL IL310652A patent/IL310652A/en unknown
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2025
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Also Published As
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| CO2024002715A2 (es) | 2024-05-20 |
| IL310652A (en) | 2024-04-01 |
| US20250127770A1 (en) | 2025-04-24 |
| WO2023014956A1 (en) | 2023-02-09 |
| AU2022323381A1 (en) | 2024-03-21 |
| JP2024529185A (ja) | 2024-08-01 |
| KR20240052765A (ko) | 2024-04-23 |
| EP4380547A1 (en) | 2024-06-12 |
| US20260053786A1 (en) | 2026-02-26 |
| PE20241385A1 (es) | 2024-07-09 |
| CA3228004A1 (en) | 2023-02-09 |
| WO2023014956A9 (en) | 2023-12-14 |
| MX2024001744A (es) | 2024-04-23 |
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