CO2024002715A2 - Formulaciones de radiprodil - Google Patents
Formulaciones de radiprodilInfo
- Publication number
- CO2024002715A2 CO2024002715A2 CONC2024/0002715A CO2024002715A CO2024002715A2 CO 2024002715 A2 CO2024002715 A2 CO 2024002715A2 CO 2024002715 A CO2024002715 A CO 2024002715A CO 2024002715 A2 CO2024002715 A2 CO 2024002715A2
- Authority
- CO
- Colombia
- Prior art keywords
- radiprodil
- formulations
- disorders
- treatment
- methods
- Prior art date
Links
- GKGRZLGAQZPEHO-UHFFFAOYSA-N 2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-n-(2-oxo-3h-1,3-benzoxazol-6-yl)acetamide Chemical compound C1=CC(F)=CC=C1CC1CCN(C(=O)C(=O)NC=2C=C3OC(=O)NC3=CC=2)CC1 GKGRZLGAQZPEHO-UHFFFAOYSA-N 0.000 title abstract 2
- 229950005702 radiprodil Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 230000001037 epileptic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente descripción proporciona, en parte, composiciones farmacéuticas que comprenden radiprodil y excipientes farmacéuticamente aceptables y métodos de uso de las mismas en el tratamiento de trastornos tales como trastornos epilépticos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163230331P | 2021-08-06 | 2021-08-06 | |
PCT/US2022/039543 WO2023014956A1 (en) | 2021-08-06 | 2022-08-05 | Formulations of radiprodil |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2024002715A2 true CO2024002715A2 (es) | 2024-05-20 |
Family
ID=83189017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2024/0002715A CO2024002715A2 (es) | 2021-08-06 | 2024-03-04 | Formulaciones de radiprodil |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP4380547A1 (es) |
KR (1) | KR20240052765A (es) |
CN (1) | CN118019521A (es) |
AU (1) | AU2022323381A1 (es) |
CA (1) | CA3228004A1 (es) |
CO (1) | CO2024002715A2 (es) |
IL (1) | IL310652A (es) |
WO (1) | WO2023014956A1 (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ2004233A3 (cs) | 2001-07-24 | 2004-12-15 | Richter Gedeon Vegyészeti Gyár Rt. | Nové amidové sloučeniny karboxylové kyseliny |
US20100010044A1 (en) * | 2008-07-08 | 2010-01-14 | Forest Laboratories Holdings Limited | Novel crystalline form of 2-[4-(4-fluoro-benzyl)-piperidine-1-yl]-2-oxo-n-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide |
AU2009282822A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating CNS disorders |
HUP0900130A3 (en) * | 2009-03-03 | 2012-02-28 | Richter Gedeon Nyrt | Novel crystalline hydrate, amorphous and polymorphic forms of dihydro-benzoxazole-6-yl-acetamide derivative and processes for their preparation |
US8328687B2 (en) | 2010-07-09 | 2012-12-11 | Ford Global Technologies, Llc | Method for controlling an engine that may be automatically stopped |
-
2022
- 2022-08-05 KR KR1020247007585A patent/KR20240052765A/ko unknown
- 2022-08-05 EP EP22764500.9A patent/EP4380547A1/en active Pending
- 2022-08-05 CA CA3228004A patent/CA3228004A1/en active Pending
- 2022-08-05 WO PCT/US2022/039543 patent/WO2023014956A1/en active Application Filing
- 2022-08-05 AU AU2022323381A patent/AU2022323381A1/en active Pending
- 2022-08-05 IL IL310652A patent/IL310652A/en unknown
- 2022-08-05 CN CN202280060141.5A patent/CN118019521A/zh active Pending
-
2024
- 2024-03-04 CO CONC2024/0002715A patent/CO2024002715A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CA3228004A1 (en) | 2023-02-09 |
EP4380547A1 (en) | 2024-06-12 |
WO2023014956A1 (en) | 2023-02-09 |
AU2022323381A1 (en) | 2024-03-21 |
WO2023014956A9 (en) | 2023-12-14 |
IL310652A (en) | 2024-04-01 |
CN118019521A (zh) | 2024-05-10 |
KR20240052765A (ko) | 2024-04-23 |
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