CN117750964A - 含有成纤维细胞的肾疾病治疗用医药组合物 - Google Patents

含有成纤维细胞的肾疾病治疗用医药组合物 Download PDF

Info

Publication number
CN117750964A
CN117750964A CN202280052893.7A CN202280052893A CN117750964A CN 117750964 A CN117750964 A CN 117750964A CN 202280052893 A CN202280052893 A CN 202280052893A CN 117750964 A CN117750964 A CN 117750964A
Authority
CN
China
Prior art keywords
fibroblasts
pharmaceutical composition
vcam1
cells
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280052893.7A
Other languages
English (en)
Chinese (zh)
Inventor
岩宫贵纮
本间顺
今村朋美
松冈柚衣美
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lymphatic Orgnex Co ltd
Original Assignee
Metcela Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metcela Inc filed Critical Metcela Inc
Publication of CN117750964A publication Critical patent/CN117750964A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202280052893.7A 2021-09-08 2022-08-23 含有成纤维细胞的肾疾病治疗用医药组合物 Pending CN117750964A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021146130 2021-09-08
JP2021-146130 2021-09-08
PCT/JP2022/031721 WO2023037868A1 (ja) 2021-09-08 2022-08-23 線維芽細胞を含む腎疾患治療用医薬組成物

Publications (1)

Publication Number Publication Date
CN117750964A true CN117750964A (zh) 2024-03-22

Family

ID=85506601

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280052893.7A Pending CN117750964A (zh) 2021-09-08 2022-08-23 含有成纤维细胞的肾疾病治疗用医药组合物

Country Status (7)

Country Link
US (1) US20240316113A1 (https=)
EP (1) EP4349349A4 (https=)
JP (1) JPWO2023037868A1 (https=)
CN (1) CN117750964A (https=)
AU (1) AU2022344667A1 (https=)
CA (1) CA3226199A1 (https=)
WO (1) WO2023037868A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3211113A1 (en) * 2021-03-04 2022-09-09 Metcela Inc. Lymphangiogenesis promoting factor-expressing fibroblast, and pharmaceutical composition containing same
CN119685401A (zh) * 2024-06-03 2025-03-25 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一种改造成纤维细胞的方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102407387B1 (ko) * 2017-02-24 2022-06-10 가부시키가이샤 메토세라 섬유아세포를 포함하고, 심장 질환들의 치료를 위하여 사용될 수 있는 주사용 조성물, 및 치료 용도를 위하여 섬유아세포를 생산하는 방법
CA3110831A1 (en) 2018-08-29 2020-03-05 Metcela Inc. Method for producing fibroblast, and g-csf-positive fibroblast mass
WO2021133790A1 (en) * 2019-12-26 2021-07-01 Figene, Llc Prevention and treatment of kidney failure by administration of fibroblasts and products thereof
CN115210361B (zh) * 2020-03-04 2024-12-10 淋巴奥格尼克斯有限公司 促红细胞生成素产生能力增强的成纤维细胞、制造方法以及医药组合物
CA3211113A1 (en) * 2021-03-04 2022-09-09 Metcela Inc. Lymphangiogenesis promoting factor-expressing fibroblast, and pharmaceutical composition containing same

Also Published As

Publication number Publication date
JPWO2023037868A1 (https=) 2023-03-16
AU2022344667A1 (en) 2024-01-25
WO2023037868A1 (ja) 2023-03-16
EP4349349A4 (en) 2025-05-21
EP4349349A1 (en) 2024-04-10
US20240316113A1 (en) 2024-09-26
CA3226199A1 (en) 2023-03-16

Similar Documents

Publication Publication Date Title
JP5240715B2 (ja) 脂肪組織由来多分化能幹細胞を含有する細胞製剤
JP6129418B2 (ja) ヒト胚性幹細胞から由来した間葉系幹細胞を有効成分として含有する肝繊維化または肝硬変予防及び治療用組成物
CN110494154B (zh) 心肌病、陈旧性心肌梗塞及慢性心力衰竭的治疗剂
KR20170091064A (ko) Ｎｏｄ２의 아고니스트를 처리한 줄기세포 또는 그 배양물을 포함하는 면역질환 또는 염증질환의 예방 또는 치료용 약학조성물
Xiang et al. Direct in vivo application of induced pluripotent stem cells is feasible and can be safe
JP2009535347A (ja) 糖尿病の治療方法
CN117750964A (zh) 含有成纤维细胞的肾疾病治疗用医药组合物
JPWO2004101775A1 (ja) 新規な成体組織由来の幹細胞およびその用途
KR20120052895A (ko) 간 절제를 위한 간 부피 증가용 조성물
KR20210148958A (ko) 치아 주변조직 유래 다분화능 줄기세포를 포함하는 비만 또는 비알코올성 지방간의 예방 또는 치료용 약학적 조성물
US20200078409A1 (en) Method for treatment of infertility, pharmaceutical composition for treatment of infertility and method for producing the same
JP2023001294A (ja) 臓器線維症の予防または治療剤
JP7499853B2 (ja) 誘導万能幹細胞由来間葉幹細胞の前駆細胞に由来するエクソソームを含む腎臓疾患の予防又は治療用組成物
KR102630220B1 (ko) 유도만능줄기세포-유래 중간엽 줄기세포 전구세포로부터 유래된 엑소좀을 포함하는 신장 질환의 예방 또는 치료용 조성물
CN115210361B (zh) 促红细胞生成素产生能力增强的成纤维细胞、制造方法以及医药组合物
KR20200132550A (ko) 편도 유래 중간엽 줄기세포 또는 이의 조정 배지를 포함하는 혈관질환 예방 또는 치료용 조성물
JP7389505B2 (ja) クローナル幹細胞を含む膵炎治療用薬学的組成物
JP7389507B2 (ja) クローナル幹細胞を含む移植片対宿主病の治療用薬学的組成物
KR102526447B1 (ko) 편도 유래 중간엽 줄기세포의 조정 배지를 포함하는 간질환 예방 또는 치료용 조성물
KR101789475B1 (ko) 편도 유래 중간엽 줄기세포 또는 이의 조정 배지를 포함하는 골다공증 예방 또는 치료용 조성물
KR101903964B1 (ko) 간세포의 재생 증대를 위한 중간엽 줄기세포의 제조방법 및 이를 이용한 간 경화 치료용 조성물
KR101776787B1 (ko) 간세포의 재생 증대를 위한 중간엽 줄기세포의 제조방법 및 이를 이용한 간 경화 치료용 조성물
EP4641205A1 (en) Method for selecting stem cells with enhanced cartilage differentiation capability and cell therapy product comprising same
KR20170091882A (ko) 편도 유래 중간엽 줄기세포 또는 이의 조정 배지를 포함하는 골다공증 예방 또는 치료용 조성물
CN110643567A (zh) 细胞培养用培养基组合物的制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20241025

Address after: London

Applicant after: Lymphatic Orgnex Co.,Ltd.

Country or region after: Britain

Address before: Kanagawa Prefecture, Japan

Applicant before: METCELA Inc.

Country or region before: Japan

TA01 Transfer of patent application right